Genomic features, antimicrobial resistance and pathogenicity assessment of Escherichia coli serotype O177:H51 strain JS01 isolated from a diseased chicken by Lunbin Xia, Guanglei Wang, Naidong Chen, Deliang Qiao, Jianwen Cao, Shaoshuai Bi

“…Further analyses were conducted to characterize its antimicrobial resistance (AMR) phenotype and pathogenicity. …”
Get full text

Sorghum-peanut intercropping under salt stress mediates rhizosphere microbial community shaping in sorghum by affecting soil sugar metabolism pathways by Xia Shao, Chunmei Yang, Yuxuan Chen, Chang Liu, Chunjuan Liu, Xiaolong Shi, Yufei Zhou

“…These correlations indicate that sorghum intercropped with peanuts can promote the enrichment of microbial taxa under salt stress, thereby enhancing soil metabolic functions and stress tolerance by optimizing the rhizosphere microbial community. …”
Get full text

Expression characteristics, molecular mechanisms, and clinical significance of DICER1 in breast cancer by Xi Zhang, Long Yu, Cuizhi Geng

“…Weighted gene co-expression network analysis (WGCNA) was used to identify gene modules associated with the breast cancer phenotype, and gene set enrichment analysis (GSEA) was performed to explore their biological functions. Cellular experiments were conducted to verify the effects of DICER1 on the proliferation, migration, and invasion of breast cancer cells. …”
Get full text

Health-related quality of life, physical and mental capacity at one year follow up of COVID-19 ICU patients: A prospective cohort study by Anders Ersson, Henrik Överengen Reuterborg, Anestis Divanoglou, Richard Levi, Lotti Orwelius

“…Secondary outcome parameters were clinimetric results for physical, mental, and cognitive functions at 6 months after intensive care stay. Results Data from 41 patients were analyzed. …”
Get full text

Examining the effects of femoral anteversion and passive hip rotation on ACL injury and knee biomechanics: a systematic review and meta‐analysis by Jennifer A. Hogg, Justin P. Waxman, Sandra J. Shultz

“…Included studies were submitted to Downs & Black Quality Assessment Tool. Meta‐analyses were conducted for comparisons including at least two studies. …”
Get full text

Multi-omics network toxicology reveals the role of benzo[a]pyrene in ovarian cancer: Integrating gut microbiota dynamics and Mendelian randomization by Jinfa Huang, Qian Yang, Lingling Zeng, Kaixian Deng

“…Protein-protein interaction networks and functional enrichment analyses were conducted utilizing Cytoscape, while molecular docking (CB-Dock 2) confirmed a strong binding affinity between BaP and core targets (e.g., HSP90AA1: −11.7; AHR: −10.0). …”
Get full text

Biomarker Investigation Using Multiple Brain Measures from MRI Through Explainable Artificial Intelligence in Alzheimer’s Disease Classification by Davide Coluzzi, Valentina Bordin, Massimo W. Rivolta, Igor Fortel, Liang Zhan, Alex Leow, Giuseppe Baselli

“…This work compares a novel DL model using structural connectivity (namely, BC-GCN-SE adapted from functional connectivity tasks) with an established model using structural magnetic resonance imaging (MRI) scans (namely, ResNet18). …”
Get full text

Effects of DCM Leaf Extract of Gnidia glauca (Fresen) on Locomotor Activity, Anxiety, and Exploration-Like Behaviors in High-Fat Diet-Induced Obese Rats by Wycliffe Makori Arika, Cromwell Mwiti Kibiti, Joan Murugi Njagi, Mathew Piero Ngugi

“…Obesity is the main component of metabolic syndromes involving distinct etiologies that target different underlying behavioral and physiological functions within the brain structures and neuronal circuits. …”
Get full text

Correlation Between Peripheral Blood Immune Cell Distribution and Disease Severity and Prognosis in Multiple Sclerosis Patients by Liu PJ, Yuan P, Liu SP

“…Pen-Ju Liu, Peng Yuan, Shui-Ping Liu Department of Neurology, Beijing Anzhen Hospital, Capital Medical University, Beijing, 100029, People’s Republic of ChinaCorrespondence: Pen-Ju Liu, Department of Neurology, Beijing Anzhen Hospital, Capital Medical University, No. 2 Anzhen Road,Chaoyang District, Beijing, 100029, People’s Republic of China, Tel +86-13521678687, Email lpjhq@163.comObjective: This study aimed to examine the relationship between peripheral blood immune cell distribution patterns and both disease severity and prognosis in patients with multiple sclerosis (MS).Methods: We conducted a retrospective analysis of clinical data from MS patients admitted to the Neurology Department of our Hospital between March 2020 and April 2024. …”
Get full text

Genome-Wide Identification and Cold Stress Response Mechanism of Barley Di19 Gene Family by Wenbo Chai, Chao Yuan, Shufen Li, Hanyuan Xu, Qing Zhu, Hongtao Li, Wei Ji, Jun Wang

“…However, little is known about their roles in barley (<i>Hordeum vulgare</i>), particularly in cold stress adaptation. This study aimed to conduct a comprehensive genome-wide analysis of the barley genome to identify Di19 gene family members and examine their expression patterns under cold stress, providing theoretical support for stress-resistant barley breeding. …”
Get full text

The relationship between immune cell infiltration and necroptosis gene expression in sepsis: an analysis using single-cell transcriptomic data by Shouyi Wang

“…Differentially expressed genes (DEGs) were identified using the limma package, and functional enrichment analysis was performed using the clusterProfiler package for Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways. …”
Get full text

Developing generalized model representations of thermal shock for local non-equilibrium heat transfer processes by E. M. Kartashov

“…The purpose of such studies is to determine basic flux patterns of complex processes occurring especially under conditions of powerful energy impacts in various technological operations. …”
Get full text

Facilitators, barriers, and recommendations for mobile health applications among Chinese older populations: a scoping review by Wilson Kin Chung Leung, Connie Yim Ching Yau, Simon Ching Lam

“…Recommended interface designs were categorized into various aspects of functional impairments (vision, manual dexterity, and cognition) of elderly users. …”
Get full text

A megbékélés józsefi paradigmája by Sarolta PÜSÖK

“…The biblical stories carry timeless messages, behavioral patterns, archetypes which are worth analyzing so that evil cannot be repeated, to stop transmitting bad schemes and empower the functional ones through biblical examples. …”
Get full text

Multi-Domain Environmental Quality of Indoor Mixed-Use Open Spaces and Insights into Healthy Living—A Quarantine Hotel Case Study by Han Wang, Wenjian Pan

“…Many hotels adopt mixed-use and open room spatial layouts, integrating diverse daily functions into a single tiny space, fostering flexible utilization and micro-scale space sharing; however, these also introduce potential health risks. …”
Get full text

Study on the Influencing Factors of Grouting Anchorage for Self-Drilling Bolts in Sandy Pebble Strata by Xiaojuan Gao, Mingchong Zhao, Chaosheng Wang, Xianglin Chen, Yugang Zhang

“…The results demonstrate that: fine particle content exerts the most significant impact on anchoring performance, with higher content reducing peak pullout resistance; the grout diffusion radius exhibits a positive correlation with grouting pressure but a negative correlation with drilling speed and grout viscosity, with viscosity having the strongest influence, followed by pressure and speed; the diffusion pattern follows a gradually decreasing trend along the drilling direction, while the radius increases at a diminishing rate with elevated pressure; when viscosity ranges from 83.3 to 833.3 mPa·s, the diffusion radius decreases by 72%; and multivariate regression analysis indicates a power function relationship between the diffusion radius and these three parameters.…”
Get full text

A Decision-Making Model for Autonomous Vehicles Considering Pedestrian&#x2019;s Time Pressure Based on Game Theory and Reinforcement Learning by Qing-Feng Lin, Heng-Yu Xue, Yang Lyu, Qing-Kun Li, Ju-Shang Ou

“…Then, leveraging game theory, we established a pedestrian crossing decision-making model considering pedestrian heterogeneity evoked by time pressure (TP). A reward function was developed to enhance driving performance by combining safety, efficiency, and comfort. …”
Get full text

Association of Korean Medicine and polypharmacy with fall risk and mortality in older adults with stroke by Ye-Seul Lee, Bo-Hyoung Jang, Jin Pyeong Jeon, Han-Gyul Lee, Seungwon Kwon, Woo-Sang Jung

“…Sensitivity analyses of the unmatched cohort, alternative outcome definitions, and interactions yielded consistent patterns.ConclusionIn older adults with stroke and polypharmacy, KM may improve functional recovery and mobility, potentially increasing falls if balance training is inadequate, yet simultaneously confer survival advantages—perhaps through neuro-immune or systemic effects—irrespective of medication load. …”
Get full text

Regulatory role of MicroRNA164 in heat and salinity stress responses via candidate target genes during seed germination in petunia by Tao Jiang, Keila Rodriguez, Sameena Ejaz Tanwir, Fangchen Liu, Fida Hussain, Jaideep Chandranshu Cherukula, Heqiang Huo

“…Phylogenetic analysis revealed nine distinct clades, indicating both conserved and divergent functions of NAC proteins. Expression analysis of miR164-targeted NAC genes showed tissue- and stress-specific patterns. …”
Get full text

SURGICAL TREATMENT OF CHEST INJURIES WITH COMBINED TRAUMA AND POLYTRAUMA: A COMPARATIVE ANALYSIS OF THE STRUCTURE AND COMPONENTS OF THE THORACIC INTERVENTION PHASE (MESSAGE ONE) by Serhii I. Panasenko, Serhii O. Guriev, Volodymyr V. Nehoduiko, Nizar R. Kerbazh

“…Rib osteosynthesis was conducted in 17 (4.2%) patients with "favorable" prognosis. …”
Get full text