Complete sequencing of the mitochondrial genome of tea plant Camellia sinensis cv. ‘Baihaozao’: multichromosomal structure, phylogenetic relationships, and adaptive evolutionary an... by Zhiyin Chen, Zhiyin Chen, Zhiyin Chen, Zhiyin Chen, Zixu Wang, Zixu Wang, Zixu Wang, Zixu Wang, Wei Zhou, Wei Zhou, Wei Zhou, Wei Zhou, Sijie Liu, Sijie Liu, Sijie Liu, Sijie Liu, Yuxin Xiao, Yuxin Xiao, Yuxin Xiao, Yuxin Xiao, Yihui Gong, Yihui Gong, Yihui Gong, Yihui Gong

“…RNA editing sites were predicted to evaluate editing patterns. Codon usage bias analysis was conducted to identify high-frequency codons. …”
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De Novo Synthesis of Anticholinergic Hyoscyamine and Scopolamine in <i>Nicotiana benthamiana</i> Based on Elucidating Tropane Alkaloid Biosynthetic Pathway of <i>Anisodus luridus</... by Mengling Wen, Junlan Zeng, Fei Qiu, Fangyuan Zhang, Zhihua Liao

“…Its high yield of hyoscyamine makes <i>A. luridus</i> a valuable plant source for commercially producing TAs. In this study, we conduct homologous gene research across transcriptome data of different tissues together with functionally tested sequences in <i>Atropa belladonna</i> as a reference and identify 13 candidate genes for TAs biosynthesis in <i>A. luridus</i>. …”
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Design and Experimentation of a Height-Adjustable Management Platform for Pineapple Fields by Sili Zhou, Fengguang He, Ganran Deng, Ye Dai, Xilin Wang, Bin Yan, Pinlan Chen, Zehua Liu, Bin Li, Dexuan Pan

“…To address the challenges of inadequate adaptability, insufficient power, high ground clearance, and limited functionality in existing pineapple field machinery, this study proposes a height-adjustable pineapple field management platform based on previously established cultivation patterns and agronomic requirements. …”
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The impact of Alzheimer's disease on cortical complexity and its underlying biological mechanisms by Leian Chen, Xiao Zhou, Yanan Qiao, Yu Wang, Zhi Zhou, Shuhong Jia, Yu Sun, Dantao Peng

“…In addition, transcription–neuroimaging association analyses, as well as Mendelian randomization of AD and cortical thickness data, were conducted to investigate the genetic mechanisms and biological functions of AD. …”
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Prevalence of poststroke fatigue and its relationship with clinical characteristics among community-dwelling stroke survivors: A cross-sectional survey by Akhila Jagadish, Manikandan Natarajan, Vasudeva Guddattu, John M. Solomon

“…Telephonic consent was obtained, and an interview was conducted to obtain the scores for fatigue, daytime sleepiness, depression, functional mobility, and disability. …”
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Roaming the Seas—Assessing Marine Invertebrate Biodiversity Along Salinity Gradients With Zooplankton and eDNA Metabarcoding by Alica Ohnesorge, Uwe John, Lucie Kuczynski, Stefan Neuhaus, Kingsly Chuo Beng, Bernd Krock, Silke Laakmann

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Evaluation of Rural Housing Structural Transformations Based on the Rural Livelihood; Case Study : Riab Village in Khorasan Razavi Province by Abasalt Askari Rabori, Shahab Abbaszadeh, Ali Asghar Abroon

“…The villages of the country have not been functioning with their full capacity for several years due to various reasons. …”
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Identifying Psychosocial, Self-Management, and Health Profiles Among Women With Chronic Pain Who Have Experienced Intimate Partner Violence and Those Who Have Not: Protocol for a 2... by Ainara Nardi-Rodríguez, Sónia Bernardes, María Ángeles Pastor-Mira, Sofía López-Roig, Lidia Pamies-Aubalat, Andrés Sánchez-Prada, Victoria A Ferrer-Pérez, Ignacio Rodríguez-Rodríguez, Purificación Heras-González

“…ResultsAs of May 2025, we had contacted relevant associations to present the project and begin recruiting voluntary participants. We have conducted the pilot study to assure the adequacy of the questionnaire and usability or technical functionality of the web-based platform. …”
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WFDC3 identified as a prognostic and immune biomarker in pancreatic cancer by Bohan Liu, Xuqing Shi, Tianqi Liu, Huanwen Wu, Zhiyong Liang

“…To address this, we conducted an initial investigation using comprehensive bioinformatic analyses to evaluate WFDCs expression patterns across multiple tumor types, with a focus on PAAD. …”
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Genome-wide characterization and expression analysis of the JRL gene family in response to hormones and abiotic stress in tomato (Solanum lycopersicum L.) by Hui Li, Hongling Hu, Lina Cao, Yue Zhuo, Liting Wang, Hui Ma, Ming Zhong

“…Our results lay the foundation for further studies on the biological functions of tomato JRL genes.…”
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Determining Groundwater Recharge from Stream Flow with Seasonal Recession Method by Ichwana -, Zulkifli Nasution, Sumono -

“…The results showed that the trend pattern of the stream hydrograph could be explained using the exponential function where the dots lowest discharge that is the end of the recession (y) than any period of time on stream hydrograph semi logarithmic (x). …”
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Bioinformatic Insights and XGBoost Identify Shared Genetics in Chronic Obstructive Pulmonary Disease and Type 2 Diabetes by Qianqian Ji, Yaxian Meng, Xiaojie Han, Chao Yi, Xiaoliang Chen, Yiqiang Zhan

“…A multifaceted bioinformatics approach, encompassing the limma R package, unified matrix analysis, and weighted gene co‐expression network analysis (WGCNA), was deployed to identify differentially expressed genes (DEGs) and hub genes. Functional enrichment and protein–protein interaction (PPI) analyses were conducted, followed by cross‐species validation in Mus musculus models. …”
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<i>Mycobacterium Ulcerans</i> Ulcer: Current Trends in Antimicrobial Management and Reconstructive Surgical Strategies by Bryan Lim, Omar Shadid, Jennifer Novo, Yi Mon, Ishith Seth, Gianluca Marcaccini, Roberto Cuomo, Daniel P. O’Brien, Warren M. Rozen

“…<b>Methods</b>: A comprehensive literature search from 1901 to 2025 was conducted across major databases to explore antimicrobial and reconstructive surgical strategies for <i>Mycobacterium ulcerans</i>. …”
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Identification and Characterization of the OCT4 Upstream Regulatory Region in Sus scrofa by Seung-Hun Kim, Kwang-Hwan Choi, Dong-Kyung Lee, Mingyun Lee, Jae Yeon Hwang, Chang-Kyu Lee

“…However, the OCT4 promoter and four regulatory regions, including distal and proximal enhancer elements, had high similarity. Next, a functional analysis of the porcine OCT4 promoter region was conducted. …”
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Repetitive transcranial magnetic stimulation ameliorates chronic pain behavior and modulates the brain transcriptome in a mouse model of chronic constriction injury by Tianying Li, Guanwen Lin, Tao Zhang, Yani Guo, Yongjin He, Jing Luan, Jin Wang, Dan Lyu, Yiqi Weng, Xin Jin

“…Transcriptomic analysis revealed that CCI induced dysregulation of 66 genes, while rTMS partially normalized gene expression patterns. Functional enrichment analysis indicated significant involvement of pathways related to inflammatory responses, transporter activity, and ion channel regulation. …”
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Integrated multi-omics analysis identifies TPX2 as a potential prognostic and immunological biomarker in hepatocellular carcinoma by Hui Peng, Yong-peng Wei, Xin-bo Liu, Yu Wang, Jian-yong Yuan

“…Methods: We conducted an integrated multi-omics analysis using transcriptomic (TCGA, GTEx, GEO), proteomic (CPTAC), and pharmacogenomic (GDSC, PRISM, CTRP) datasets to assess TPX2 expression patterns in HCC. …”
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Challenges and opportunities for data integration to improve estimation of migratory connectivity by Jeffrey A. Hostetler, Emily B. Cohen, Christen M. Bossu, Amy L. Scarpignato, Kristen Ruegg, Andrea Contina, Clark S. Rushing, Michael T. Hallworth

“…Integration of the diverse measures of migratory movements can help elucidate migratory connectivity patterns with methodology that accounts for differences in sampling design, directionality, effort, precision and bias inherent to each data type. …”
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Atypical early neural responses to native and non-native language in infants at high likelihood for developing autism by Lauren Wagner, Megan Banchik, Tawny Tsang, Nana J. Okada, Rebecca Altshuler, Nicole McDonald, Susan Y. Bookheimer, Shafali S. Jeste, Shulamite Green, Mirella Dapretto

“…Methods In this study, we used functional magnetic resonance imaging (fMRI) to examine differences in language processing in 9-month-old infants at high (HL) and typical (TL) familial likelihood for ASD. …”
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DHCR24 overexpression is involved in lipid metabolic reprogramming to drive cervical cancer malignant progression and is associated with immune microenvironment by Lin Cheng, Yuance Xu, Zhuo Li, Danting Sun, Yan Xu, Junqi He, Yulong Chen, Qin Yao

“…A prognostic nomogram incorporating tumor stage and DHCR24 expression levels was developed to predict clinical outcomes in patients. Functional studies using SiHa cell lines were conducted to elucidate the oncogenic properties of DHCR24. …”
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An Experimental Dynamic Investigation of the Influence of Melatonin, Serotonin and Tryptophan on the Stability of the DNA Structure by Cristina Manuela Drăgoi, Anca Zanfirescu, Ion-Bogdan Dumitrescu, Anca Ungurianu, Denisa Marilena Margină, Alina-Crenguţa Nicolae

“…Tryptophan, an essential amino acid, serves as a vital structural element in proteins and a precursor for bioactive compounds like serotonin and melatonin, which impact various physiological functions. Methods: Experimental studies have been conducted to reveal the interaction mechanisms of these endogenous indole derivatives with calf thymus DNA (ct-DNA). …”
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