Triglyceride-independent associations between circulating levels of apolipoprotein C-III and biomarkers of inflammation by Dídac Llop, Pere Rehues, Silvia Paredes, Montse Guardiola, Josefa Girona, Roser Rosales, Yaiza Esteban, Lluís Masana, Daiana Ibarretxe, Joan-Carles Vallvé, Josep Ribalta

“…Correlation and multivariate linear regression analyses were conducted. Results ApoCIII levels were significantly and positively associated with Glyc-A, Glyc-B, and Glyc-F levels across all cohorts. …”
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Age-Onset-Related Particularities of Pediatric MS—Understanding the Spectrum: A Tertiary Center Experience by Alice Denisa Dică, Dana Craiu, Florentina Ionela Linca, Magdalena Budișteanu, Catrinel Iliescu, Carmen Sandu, Cristina Pomeran, Diana Bârcă, Niculina Butoianu, Carmen Burloiu, Ioana Minciu, Ina Ofelia Focșa, Dana Surlică, Oana Tarța-Arsene, Cristina Cazacu, Andreea Badea, Alexandru Stefan Niculae, Daniela Adriana Ion

“…Intermediate-onset patients presented overlapping features of both early and late-onset MS and had the highest proportion of fully preserved motor function (EDSS 0) at the end of follow-up. MRI findings revealed more extensive and confluent lesions in younger patients, particularly in the first two years after onset. …”
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Molecular characteristics and cancer immunity of LRP1B and its relationship with the Hedgehog signaling pathway in colorectal cancer by Yuan Liu, Yuan Liu, Yang Zhong, Yang Zhong, Yaodong Sang, Yaodong Sang, Siqiang Zhu, Siqiang Zhu, Kang Xu, Kang Xu, Xingyu Zhu, Xingyu Zhu, Xiaoling Cui, Xiaoling Cui, Xinyu Liu, Xinyu Liu, Xiaohan Wang, Xiaohan Wang, Hao Chen, Changqing Jing, Changqing Jing, Wei Chong, Wei Chong, Leping Li, Leping Li

“…Cellular and molecular experiments were conducted to validate our findings.ResultsOur analysis implicated LRP1B as a tumor suppressor gene. …”
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Cloning and expression profile of an ubiquitin-conjugating enzyme-like gene OsCROC-1A in rice (Oryza sativa L.) by WANG Ya, LIU Jianping, XU Mengyun, JI Weijie, TU Jumin, ZHANG Xiaobo

“…Real-time quantitative PCR was conducted to analyze the spatial expression pattern of OsCROC-1A as well as the changes of its expression level under abiotic stresses. …”
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Population prevalence and correlates of prolonged and shortened QTc intervals in a nationwide survey of adults in China: a report from Chinese arrhythmia epidemiology cross-section... by Li-Guo Tan, Li-Guo Tan, Jing-Xuan Liu, Fei Guo, Jing Lin, Ran Xiong, Hao Fu, Hao-Ming You, Liu He, Shi-Jun Xia, Xin Du, Jian-Zeng Dong

“…This study aimed to elucidate the distribution of the QT interval (QTc) patterns in Chinese adults and the risk factors associated with a prolonged QTc interval and shortened QTc interval.MethodsThis study was based on data from the Chinese Arrhythmia Epidemiology Cross-Sectional Study conducted in seven provinces of China between 2014 and 2016. …”
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Using five exposure metrics to explore the association between ambient PM2.5 and the hospital admissions for COPD in Tianshui city, China by Deshun Li, Jiyuan Dong, Xiaoju Liu, Juan Shu, Lisha Zhu, Hairong Bao

“…Stratified analyses were conducted to examine the effect modifications of gender, age, and season. …”
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Transcriptomic profiling and bioinformatic insights into myocardial injury following aneurysmal subarachnoid hemorrhage by Zuoli Wu, Zuoli Wu, Wenbo He, Weihao Ye, Shang Xu, Shengwei Wei, Baozi Huang, Pingping Li, Yanyan Tang, Chao Qin, Ying Liu, Ziming Ye

“…While RNA plays a critical role in pathophysiological processes, its expression patterns and functions in myocardial injury after aSAH (aSAH-MI) remain poorly understood.ObjectiveTo construct the RNA expression profile of aSAH-MI patients, explore their biological functions, and establish a gene expression regulatory network for aSAH-MI. …”
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Combined effects of acidification and warming on soil denitrification and microbial community by Peiyuan Xu, Peiyuan Xu, Mengke Gao, Mengke Gao, Yuchen Li, Yuchen Li, Jun Ye, Jianqiang Su, Jianqiang Su, Hu Li, Hu Li

“…In light of the challenges posed by contemporary global warming and soil acidification, the respective effects of pH and temperature on soil microbiome and functions have been explored. However, the combined influence of acidification and warming on soil denitrification and active microbial communities are still unclear. …”
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The Efficacy and Brain Network Mechanism of Acupuncture for Knee Osteoarthritis: A Study Protocol for Randomized Controlled Neuroimaging Trial by Sun YY, Wang ML, Zhao RH, Hao MY, Song S, Zhou Y, Zhang N

“…Forty healthy subjects will be recruited for observation, with a single MRI scan conducted only at baseline (− 1– 0 week). The primary efficacy indicator will be the change in NRS score after four weeks of treatment, with secondary outcomes including WOMAC, STAI, and safety assessments. fMRI observations will employ independent component analysis, brain network construction, and functional connectivity, complemented by Pearson correlation analysis to explore the relationship between brain responses and clinical improvements.Conclusion: This study will initially uncover how acupuncture intervention for chronic KOA pain centrally regulates and exerts therapeutic effects through the modulation of abnormal brain network functional connectivity patterns, with a demonstrated long-term effect.Ethics and Dissemination: This study has been approved by the ethics committee of Shandong University of Traditional Chinese Medicine Affiliated Hospital ((2024) Lunshen No. (028) - KY).Clinical Trial Registration: This study has been approved by registered in the Chinese Clinical Trial Registry (ChiCTR2400083695).Keywords: acupuncture, knee osteoarthritis, neuroimaging, RCT, protocol…”
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Single-cell transcriptomic dynamics of scallop heart reveals the heterogeneous response to heat stress by Danyang Wang, Na Liu, Xiangfu Kong, Xinghai Zhu, Yangfan Wang, Jingjie Hu, Zhenmin Bao

“…Conclusions Our study investigated the heterogeneous response of the scallop heart to high temperatures, revealing distinct response patterns between VMs and AMs. We further identified a key gene, AiPLRP2-like, which exhibits unique cellular localization patterns compared to its mammalian counterpart and may play a pivotal role in regulating cardiac thermotolerance in organisms with open circulatory systems. …”
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Single-cell sequencing reveals cell heterogeneity and aberrantly activated pathways associated with microvascular invasion in hepatocellular carcinoma by Jianwei Cui, Fanyi Zeng, Ming Tang, Ming Tang, Shiwu Yin, Shiwu Yin

“…Additionally, MARCKSL1 is linked to tumour resistance to multiple anticancer drugs.DiscussionThis study sheds light on the molecular characteristics and functional heterogeneity of MVI-associated malignant cell subpopulations. …”
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Biochemical and Transcriptomic Analysis Reveals Low Temperature-Driven Oxidative Stress in Pupal <i>Apis mellifera</i> Neural System by Xiangjie Zhu, Mingjie Cao, Chenyang Li, Chenyu Zhu, Han Li, Yuanmingyue Tian, Jiaqi Shang, Jiaqi Sun, Bingfeng Zhou, Xianda Wu, Shujing Zhou, Xinjian Xu

“…RT-qPCR validation was conducted on 11 core enriched genes in pathways identified via GSEA, and all these genes exhibited a downregulated expression pattern, confirming the inhibition of glutathione metabolism and peroxisome function under low-temperature stress. …”
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Ocean alkalinity enhancement approaches and the predictability of runaway precipitation processes: results of an experimental study to determine critical alkalinity ranges for safe... by N. Suitner, G. Faucher, C. Lim, J. Schneider, C. A. Moras, U. Riebesell, J. Hartmann

“…The experiments lasted for 20–25 <span class="inline-formula">d</span> to monitor the temporal development of carbonate chemistry parameters after alkalinity addition and the subsequent triggered carbonate precipitation process. Identified uniform patterns before and during the triggered runaway process can be described by empirical functional relationships. …”
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On some problems of analysis and assessment of the influence of the human factor on the safety of technical systems by D. I. Lobach

“…The purpose of the theoretical research of the article is to formulate and describe cases in which it is possible to conduct correlation and other types of analysis for some situations to quantify the impact of the human factor on safety of technical systems using plausible patterns and statistical distributions, to consider some problems and reliability issues that arise in the course of solving such problems.Method. …”
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Análise da utilização de coleções digitais: o caso do Museu Nacional de Machado de Castro by Ana Rita Costa

“…The aim was to identify the users of the MNMC digital collection, their motivations and usage patterns, including the evaluation of their satisfaction regarding available content and functionalities, and identify areas of improvement. …”
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Genome-wide identification and integrated analysis of the WNK kinase gene family and expression analysis of PgWNK genes under methyl jasmonate treatment in Panax ginseng by Kexin Zhang, Aimin Wang, Lin Shi, Jiaqing Liu, Yu Zhang, Yang Jiang, Meiping Zhang, Yi Wang, Mingzhu Zhao, Kangyu Wang

“…However, there are no reports on the effects of WNK in ginseng under methyl jasmonate (MeJA) treatment. In this study, we conducted a detailed screening, identification, and systematic research on the WNK gene family in ginseng, including phylogenetic relationships, gene structure, chromosomal distribution, GO functional classification, cis-regulatory elements, co-expression network analysis, and gene expression pattern analysis. …”
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Human Action Recognition Based on The Skeletal Pairwise Dissimilarity by E.E. Surkov, O.S. Seredin, A.V. Kopylov

“…The main idea of the paper is to apply the principles of featureless pattern recognition to human activity recognition problem. …”
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Comprehensive profiling of the gut microbiota in patients with chronic obstructive pulmonary disease of varying severity. by Yu-Chi Chiu, Shih-Wei Lee, Chi-Wei Liu, Rebecca Chou-Jui Lin, Yung-Chia Huang, Tzuo-Yun Lan, Lawrence Shih-Hsin Wu

“…However, the abundance of a Bacteroides was associated with blood eosinophils and lung function. This study suggests that no distinctive gut microbiota pattern is associated with the severity of COPD. …”
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Quinoa–Peanut Relay Intercropping Promotes Peanut Productivity Through the Temporal Optimization of Soil Physicochemical Properties and Microbial Community Composition in Saline So... by Xiaoyan Liang, Rao Fu, Jiajia Li, Yinyu Gu, Kuihua Yi, Meng Li, Chuanjie Chen, Haiyang Zhang, Junlin Li, Lan Ma, Yanjing Song, Xiangyu Wang, Jialei Zhang, Shubo Wan, Hongxia Zhang

“…The quinoa–peanut relay intercrop pattern (IP) is a promising planting system that utilizes the biological advantages of quinoa to improve soil ecological functions and productivity. …”
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Comprehensive multi-omics characterization of different cuts of Dezhou donkey meat by Yu Tian, Wei Zhang, Chenxi Gao, Han Wang, Junjie Wang, Shunfeng Cheng, Shuer Zhang, Min Zhang, Jianjun Li, Yujiang Sun, Wei Shen, Shuqin Liu

“…This study presents an in-depth analysis of meat quality traits and gene expression patterns across various donkey meat cuts, highlighting the key functional genes involved. …”
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