Age-linked DNA methylation and gene expression patterns in parameningeal head and neck alveolar rhabdomyosarcoma reveal CDK9 as a promising therapeutic target by Sara Patrizi, Silvia Vallese, Sabina Barresi, Matteo Cassandri, Isabella Giovannoni, Lucia Pedace, Luana Abballe, Flavia Vinciarelli, Celeste Antonacci, Alessandra Stracuzzi, Barbara Mancini, Ida Russo, Angela Di Giannatale, Rossella Rota, Rita Alaggio, Franco Locatelli, Giuseppe Maria Milano, Evelina Miele

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Detection of Myocardial Deformation Patterns and Prognostic Value of Routine Echocardiographic Parameters in Patients with Cardiac Sarcoidosis Versus Extracardiac Sarcoidosis: Syst... by Hritvik Jain, Maryam Shahzad, Muhammad Usman, Anil KC, Jagjot Singh, Jyoti Jain, Ramez M. Odat, Aman Goyal, Faizan Ahmed, Raheel Ahmed

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Morphologic Pattern Differences in Reconstructive Tissue Repair of Bone Defects Mediated by Bioactive Ceramics and Hydrogels: A Microscopic Follow-Up Evaluation of Re-Ossification by Róbert Boda, Viktória Hegedűs, Sándor Manó, Andrea Keczánné-Üveges, Balázs Dezső, Csaba Hegedűs

“…Although publications have documented the osteo-inductive effects of various bioactive materials on tissue sections, the associated morphologic patterns of tissue remodeling pathways at the cellular level have not been detailed. …”
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The effect of using red algae powder on growth indices, some serum and mucus indices, and mucus protein patterns in common carp (Cyprinus carpio) fry by Fatemeh Abdollahnejad, Seyed Hossein Hoseinifar, Hamed Paknejad, Abdolmajid Hajimoradlou, Mohamdreza Imanpuor

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PDGFRα promoter polymorphisms and expression patterns influence risk of development of imatinib-induced thrombocytopenia in chronic myeloid leukemia: A study from India by Sameer Ahmad Guru, Rashid Mir, Musadiq Bhat, Imtiyaz Najar, Mariyam Zuberi, Mamta Sumi, Mirza Masroor, Naresh Gupta, Alpana Saxena

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Deep Learning-Based Dzongkha Handwritten Digit Classification by Yonten Jamtsho, Pema Yangden, Sonam Wangmo, Nima Dema

“…With the advancement in deep learning technology, many machine learning algorithms were developed to tackle the problem of pattern recognition. The purpose of conducting the research is to create the first-ever Dzongkha handwritten digit dataset and develop a model to classify the digit. …”
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Functional Tests\' Sensitivity and Specificity for Return to Sport After ACL Reconstruction: A Scoping Review by Parisa Sedaghati, Mohammad Ghafoori, Ali Parvaneh Sarand

“…Methods: This scoping review conducted an extensive survey of functional tests to assess the ability to RTS after ACL injuries. …”
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Experimental investigation of gas seepage characteristics in coal seams under gas-water-stress function by Zunguo Zhang, Chao Tang, Yi Chen, Yongqiang Chen, Honghu Zhang, Yifu Zhang

“…The relationship between permeability and effective stress can be modeled using either a quadratic or logarithmic function. On the other hand, the connection between permeability and moisture content, can be represented by a quadratic or exponential function. …”
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The Spatial‐Temporal Alternative Splicing Profile Reveals the Functional Diversity of FXR1 Isoforms in Myogenesis by Wei Wang, Xinhao Fan, Weiwei Liu, Yuxin Huang, Shuhong Zhao, Yalan Yang, Zhonglin Tang

“…Collectively, these findings provide a comprehensive resource for AS studies in skeletal muscle development, underscoring the diverse functions and regulatory mechanisms governing distinct Fxr1 isoforms in myogenesis.…”
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Human congenital cataract mutation in MYH9 alters F-actin organization and cell functions by Hao Yuan, Zhen-Yu Wang, Jia-Rui Yang, Chen Huang, Liang Zhu, Xue-Min Li

“…Cell counting kit-8 (CCK8), wound-healing and double staining flow cytometry assays were performed to evaluate the proliferation, migration and apoptosis function of transfected cells, respectively. Transmission electron microscope was conducted to observe the alteration of organelle structure. …”
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Functional Identification Reveals That TaTGA16-2D Promotes Drought and Heat Tolerance by Jingna Ru, Jiamin Hao, Xiaoqian Ji, Bingqing Hao, Jiale Yang, Hongtao Wang, Baoquan Quan, Pengyan Guo, Jiping Zhao, Chao Wang, Huawei Shi, Zhaoshi Xu

“…Overall, this study provides valuable insights into the evolution and functional roles of <i>TaTGAs</i> and identifies <i>TaTGA16-2D</i> as a promising candidate to enhance abiotic stress tolerance in wheat via molecular breeding.…”
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Fractal phototherapy: impact on the structure and function of the retina of rabbits with modelled retinal pigment epithelium atrophy by D. V. Fadeev, N. V. Neroeva, M. V. Zueva, I. V. Tsapenko, V. I. Kotelin, T. A. Pavlenko, O. V. Beznos, T. D. Okhotsimskaya, P. A. Ilyukhin, Yu. S. Timofeev

“…A positive effect of FF on the functional activity of retinal ganglion cells (RGC) may suggest that prescribing a course of FF lasting up to 1 month (20 sessions) in diseases accompanied by a pathology of RGC is advisable, whereas for patients with a pathology of the macular region, such as AMD, an effective improvement in the activity of photoreceptors and bipolar cells could probably be achieved through a 1-week course of FF, conducted under the control of electroretinography.…”
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Prevalence of Palatally Displaced Canines and Their Association with Dental and Skeletal Anomalies: A Retrospective Study by Alicia Martínez-González, María Elena Montes-Díaz, Nuria Esther Gallardo-López, Pedro Colino-Gallardo, Laura Criado-Pérez, Alfonso Alvarado-Lorenzo

“…Maxillary canines have a vital importance in the dental arches, both esthetically and functionally. They are the second most frequently impacted teeth, with palatal impaction being the most common. …”
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Empirical assessment of functional somatic disorder (FSD): frequency, applicability, and diagnostic refinement in a population-based sample by Abigail Smakowski, Judith Rosmalen, Bernd Löwe, Christopher Burton, Anne Toussaint

“…In response, the international research network EURONET-SOMA has proposed a diagnostic classification for persistent and troublesome symptoms entitled “functional somatic disorder (FSD)”. Focusing on symptom patterns across organ systems, the FSD approach aims to enhance diagnosis, treatment, and healthcare access for patients. …”
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Emotional responses to auditory hierarchical structures is shaped by bodily sensations and listeners’ sensory traits by Maiko Minatoya, Tatsuya Daikoku, Yasuo Kuniyoshi

“…However, for some individuals, these auditory-induced emotions can become distressing enough to interfere with daily functioning. Despite the prevalence of these experiences, the mechanisms underlying auditory-induced emotional responses remain only partially understood. …”
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Human Metabolism of Sirolimus Revisited by Baharak Davari, Touraj Shokati, Alexandra M. Ward, Vu Nguyen, Jost Klawitter, Jelena Klawitter, Uwe Christians

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Genome-Wide Identification and Expression Analysis of the <i>Shaker</i> K⁺ Channel Gene Family in Cassava (<i>Manihot esculenta</i> Crantz) Under Potassium Stress by Xianhai Xie, Chenyu Lin, Feilong Yu, Haozheng Li, Jin Xiao, Mingjuan Zheng, Wenquan Wang, Xin Guo

“…Tissue-specific expression pattern analysis showed that <i>MeGORK</i> and <i>MeAKT1.2</i> were expressed in all tissues. …”
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Study on the relationship between topological characteristics of vegetation ecospatial network and sand fixation function in the Mongolian Plateau

“…These findings can provide insights into optimizing vegetation patterns and enhancing sand fixation function. © 2025 The Authors…”
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Autonomic correlates of osteopathic manipulative treatment on facial functional mapping: an innovative approach based on thermal imaging by Francesco Cerritelli, David Perpetuini, Jordan Keys, Arcangelo Merla, Daniela Cardone

“…The comparative analysis of thermal maps and SCA results represents a significant advancement in our understanding of the physiological mechanisms underlying OMT’s effects on autonomic functions. By elucidating specific patterns of temperature change, correlation intensity and specific clusters, this research provides valuable insights for optimizing clinical practice and refining theoretical models of manual therapy.…”
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Structural and functional imaging studies in chronic cannabis users: a systematic review of adolescent and adult findings. by Albert Batalla, Sagnik Bhattacharyya, Murat Yücel, Paolo Fusar-Poli, Jose Alexandre Crippa, Santiago Nogué, Marta Torrens, Jesús Pujol, Magí Farré, Rocio Martin-Santos

“…<h4>Background</h4>The growing concern about cannabis use, the most commonly used illicit drug worldwide, has led to a significant increase in the number of human studies using neuroimaging techniques to determine the effect of cannabis on brain structure and function. We conducted a systematic review to assess the evidence of the impact of chronic cannabis use on brain structure and function in adults and adolescents.…”
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