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1761
Genome-wide identification, expression analysis, and response to abiotic stress of the phosphate transporter gene family in cucumber (Cucumis sativus L.)
Published 2025-05-01“…Conclusion This study conducted a systematic analysis of the CsPHT gene family, which provides a theoretical foundation and candidate genes for subsequent functional characterization and the genetic improvement of abiotic stress tolerance in cucumber.…”
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1762
Integrated genomic and transcriptomic analysis of polydactyly in chickens
Published 2025-05-01“…These findings offer clear targets for functional validation and may guide selective breeding for limb traits in poultry.…”
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1763
Insights into the blood, gut, and oral microbiomes in Chinese patients with myocardial infarction: a case-control study
Published 2025-04-01“…Differential analyses were conducted to find key differential microbiota for MI. …”
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1764
Single-cell technology reveals the crosstalk between tumor cells and immune cells: driving immune signal transduction and inflammation-mediated cardiac dysfunction in the tumor mic...
Published 2025-08-01“…Prognostic modeling was conducted using Cox regression and LASSO. Immune infiltration and drug sensitivity were evaluated by CIBERSORT, ESTIMATE, xCell, TIDE, and pRRophetic. …”
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1765
Patient experience in retinitis pigmentosa and Choroideremia– a concept elicitation study in 17 patients based on qualitative interviews
Published 2025-08-01“…Despite different underlying genetic pathways, they have many progression patterns in common, first affecting the more peripheral retina and later advancing toward the central retina. …”
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1766
Clinical characteristics of obsessive-compulsive disorder comorbid with obsessive -compulsive personality disorder: subtype implications
Published 2025-07-01“…Diagnostic assessments were conducted according to the criteria of the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5). …”
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1767
Mechanistic study of CTHRC1 in promoting Wilms’ tumor progression by regulating M2-type tumor-associated macrophages polarization
Published 2025-07-01“…In vitro and in vivo experiments were performed to investigate the biological functions of CTHRC1 in WT and its effects on M2-TAMs polarization. …”
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1768
Genome-wide identification of the regulatory network of mitogen-activated protein kinase signaling cascades gene families in Hevea Brasiliensis
Published 2025-05-01“…Integrating the interaction network and gene expression patterns, 12 potential HbMPK cascade signaling modules including HbMPKKK6/41/79-HbMPKK1-HbMPK9/12/15 and HbMPKKK6/14/21/41/79-HbMPKK9-HbMPK9/15 might involve in NR production and stress responses. …”
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1769
Effect of Chlorhexidine and Benincasa Hispida Pretreatment on Microshear Bond Strength of Universal Adhesive System on Dentin: A Pilot Study
Published 2024-11-01“…Benincasa hispida is a natural plant-based functional food containing minerals and vitamins that help prevent osteoporosis and improve bone health. …”
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1770
Genome-Wide Identification and Expression Analysis of <i>NAC</i> Gene Family Members in Seashore Paspalum Under Salt Stress
Published 2024-12-01“…The transcriptomic analysis investigates the expression patterns of <i>NAC</i> genes in both leaves and roots under varying durations of salt stress. …”
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1771
A novel NFKB1 agonist remodels tumor microenvironment and activates dendritic cells to promote anti-tumor immunity in colorectal cancer
Published 2025-05-01“…We then performed functional validation using a mouse colorectal cancer graft tumor model established with the CT26 cell line characterized by its high content of CSCs. …”
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1772
Dynamics of cerebral blood flow following sertraline treatment in adolescent depression
Published 2025-07-01“…Among the depressed cohort, 25 participants adhered to the treatment protocol and completed MRI scans. Resting-state functional MRI (rs-fMRI) scans were conducted for all participants, with a subsequent scan for the depression group after 8 weeks of sertraline therapy. …”
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1773
Navigating Nepal's health financing system: A road to universal health coverage amid epidemiological and demographic transitions.
Published 2025-01-01“…Policies and content related to the health financing system were reviewed to understand the status, issues and challenges of health financing functions, and UHC . A framework-guided deductive content analysis approach was employed, and findings were interpreted using the three UHC components: service coverage, population coverage, and financial coverage.…”
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1774
Identification and Mechanistic Studies of Key Genes in Thalamic Hemorrhage Pain by Multi-omics
Published 2025-07-01“…Multi-omics analyses yielded distinct profiles of DEGs, single-cell DEGs, DEPs, RF-DEGs, and DEMs, which were functionally annotated through enrichment strategies. …”
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1775
The novel diagnostic markers for systemic lupus erythematosus and periodontal disease
Published 2025-07-01“…Protein-protein interaction (PPI) network analysis was conducted to explore relationships between hub genes. …”
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1776
Exploring the role of ferroptosis in pemphigus: identification of diagnostic markers and regulatory mechanisms
Published 2025-06-01“…This study aims to investigate the expression patterns and potential biological functions of ferroptosis-related genes in pemphigus, as well as their regulatory mechanisms.MethodsTo achieve this, skin samples from five pemphigus patients and five healthy controls were collected from Fujian Medical University Union Hospital. …”
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1777
Assessing the prognostic and therapeutic value of cuproptosis-related genes in colon adenocarcinoma patients
Published 2025-04-01“…Using the Weighted Gene Co-expression Network Analysis (WGCNA) method, we identified the gene module most strongly linked to cuproptosis and conducted functional enrichment analysis to explore the roles of genes within this module in COAD tumorigenesis. …”
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1778
Experiences of discrimination are associated with microbiome and transcriptome alterations in the gut
Published 2024-10-01“…Gene expression analysis revealed distinctive patterns, with significant changes in genes associated with environmental sensing (two-component system) and metabolic pathways. …”
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1779
Identification and Expression Analysis of the Phospholipase D Gene Family in Rice
Published 2024-12-01“…【Objective】Phospholipase D (PLD) plays a crucial role in plant growth, development, and stress response. The study was conducted to explore the PLD gene family members involved in biotic and abiotic stress in rice (Oryza sativa L.) and investigate their biological functions.…”
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1780
Helminth Coinfections Modulate Disease Dynamics and Vaccination Success in the Era of Emerging Infectious Diseases
Published 2025-04-01“…<b>Methods</b>: This systematic review conducted in line with the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020 guidelines synthesizes the current evidence, identifies patterns, and highlights areas needing further research, offering a cohesive understanding of the topic. …”
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