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  1. 1761

    Genome-wide identification, expression analysis, and response to abiotic stress of the phosphate transporter gene family in cucumber (Cucumis sativus L.) by Kunhao Xie, Mintao Sun, Xiaoqin Wang, Xiaoya Zhou, Qinghua Di, Yang Li, Guoxiu Wu, Yansu Li, Chaoxing He, Shengli Li

    Published 2025-05-01
    “…Conclusion This study conducted a systematic analysis of the CsPHT gene family, which provides a theoretical foundation and candidate genes for subsequent functional characterization and the genetic improvement of abiotic stress tolerance in cucumber.…”
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  2. 1762

    Integrated genomic and transcriptomic analysis of polydactyly in chickens by Zhiying Huang, Xiaomeng Miao, Diyan Li, Jia Liu, Haolin Chen, Yuan Su, Yuan Su

    Published 2025-05-01
    “…These findings offer clear targets for functional validation and may guide selective breeding for limb traits in poultry.…”
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  3. 1763
  4. 1764

    Single-cell technology reveals the crosstalk between tumor cells and immune cells: driving immune signal transduction and inflammation-mediated cardiac dysfunction in the tumor mic... by Wenyang Nie, Wangzheqi Zhang, Zhikai Xiahou, Yuxuan Meng, Yuhang Liu, Jingwen Zhang, Zhen Wang, Yong Wang

    Published 2025-08-01
    “…Prognostic modeling was conducted using Cox regression and LASSO. Immune infiltration and drug sensitivity were evaluated by CIBERSORT, ESTIMATE, xCell, TIDE, and pRRophetic. …”
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  5. 1765

    Patient experience in retinitis pigmentosa and Choroideremia– a concept elicitation study in 17 patients based on qualitative interviews by Elke Rometsch, Per-Olof Thuresson, Noémie Hurst, Eckhart Eule, Isabel Bachmeier, Benoit Blanchard, José-Alain Sahel, Isabelle Audo

    Published 2025-08-01
    “…Despite different underlying genetic pathways, they have many progression patterns in common, first affecting the more peripheral retina and later advancing toward the central retina. …”
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    Article
  6. 1766

    Clinical characteristics of obsessive-compulsive disorder comorbid with obsessive -compulsive personality disorder: subtype implications by Ayse Dondu, Levent Sevincok

    Published 2025-07-01
    “…Diagnostic assessments were conducted according to the criteria of the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5). …”
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  7. 1767

    Mechanistic study of CTHRC1 in promoting Wilms’ tumor progression by regulating M2-type tumor-associated macrophages polarization by Yingquan Zhuo, Xiaoyun Feng, Wenqi Zhang, Jun Du, Xu Sun, Xi Luo, Wei Wang, Hua Jiang, Huajian Gu

    Published 2025-07-01
    “…In vitro and in vivo experiments were performed to investigate the biological functions of CTHRC1 in WT and its effects on M2-TAMs polarization. …”
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    Article
  8. 1768

    Genome-wide identification of the regulatory network of mitogen-activated protein kinase signaling cascades gene families in Hevea Brasiliensis by Xiaojuan Huang, Manman Sun, Xiaoyu Du, Lin Quan, Jinquan Chao, Xiaomin Deng, Hongze Liao

    Published 2025-05-01
    “…Integrating the interaction network and gene expression patterns, 12 potential HbMPK cascade signaling modules including HbMPKKK6/41/79-HbMPKK1-HbMPK9/12/15 and HbMPKKK6/14/21/41/79-HbMPKK9-HbMPK9/15 might involve in NR production and stress responses. …”
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    Article
  9. 1769

    Effect of Chlorhexidine and Benincasa Hispida Pretreatment on Microshear Bond Strength of Universal Adhesive System on Dentin: A Pilot Study by Girija S Sajjan, Manda Sri Swathi, P Arun Bhupathi, Madhu Varma Kanumuri, Rajulapati Kalyan Satish, Rama Krishna Alla, Tippireddy Srija, Ch Uma Shalini

    Published 2024-11-01
    “…Benincasa hispida is a natural plant-based functional food containing minerals and vitamins that help prevent osteoporosis and improve bone health. …”
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  10. 1770

    Genome-Wide Identification and Expression Analysis of <i>NAC</i> Gene Family Members in Seashore Paspalum Under Salt Stress by Xuanyang Wu, Xiaochen Hu, Qinyan Bao, Qi Sun, Pan Yu, Junxiang Qi, Zixuan Zhang, Chunrong Luo, Yuzhu Wang, Wenjie Lu, Xueli Wu

    Published 2024-12-01
    “…The transcriptomic analysis investigates the expression patterns of <i>NAC</i> genes in both leaves and roots under varying durations of salt stress. …”
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  11. 1771

    A novel NFKB1 agonist remodels tumor microenvironment and activates dendritic cells to promote anti-tumor immunity in colorectal cancer by Ying Chen, Qiaoming Li, Zixiang Wang, Ling V. Sun, Steven X. Hou

    Published 2025-05-01
    “…We then performed functional validation using a mouse colorectal cancer graft tumor model established with the CT26 cell line characterized by its high content of CSCs. …”
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  12. 1772

    Dynamics of cerebral blood flow following sertraline treatment in adolescent depression by Wenyu Ren, Wenyu Ren, Xiao Liu, Zhiwei Zhang, Xiaoqin Zhang, Wei Wu, Xingyu Wang, Zhihui Yu, Chuan Liu, Renqiang Yu

    Published 2025-07-01
    “…Among the depressed cohort, 25 participants adhered to the treatment protocol and completed MRI scans. Resting-state functional MRI (rs-fMRI) scans were conducted for all participants, with a subsequent scan for the depression group after 8 weeks of sertraline therapy. …”
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  13. 1773

    Navigating Nepal's health financing system: A road to universal health coverage amid epidemiological and demographic transitions. by Resham B Khatri, Pratik Khanal, Dipendra Singh Thakuri, Prabesh Ghimire, Mihajlo Jakovljevic

    Published 2025-01-01
    “…Policies and content related to the health financing system were reviewed to understand the status, issues and challenges of health financing functions, and UHC . A framework-guided deductive content analysis approach was employed, and findings were interpreted using the three UHC components: service coverage, population coverage, and financial coverage.…”
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  14. 1774

    Identification and Mechanistic Studies of Key Genes in Thalamic Hemorrhage Pain by Multi-omics by Chen Yang, Ju Gao, Yaqun Li, Yinggang Xiao, Tianfeng Huang

    Published 2025-07-01
    “…Multi-omics analyses yielded distinct profiles of DEGs, single-cell DEGs, DEPs, RF-DEGs, and DEMs, which were functionally annotated through enrichment strategies. …”
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  15. 1775

    The novel diagnostic markers for systemic lupus erythematosus and periodontal disease by Xuedi Cheng, Jinfeng Zhang, Jiali Hou, Xiaocui Han, Bin Han, Jun Zhou, Zhongjun Wang, Junzheng Wang

    Published 2025-07-01
    “…Protein-protein interaction (PPI) network analysis was conducted to explore relationships between hub genes. …”
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  16. 1776

    Exploring the role of ferroptosis in pemphigus: identification of diagnostic markers and regulatory mechanisms by Jing Mao, Jianping Lan, Zheyu Zhuang, Ying Chen, Ying Chen, Yushan Ou, Xinhong Su, Xueting Zeng, Fuchen Huang, Zequn Tong, Xiaoqing Lv, Xiaoqing Lv, Xiaoqing Lv, Hui Ke, Zhenlan Wu, Ying Zou, Bo Cheng, Bo Cheng, Bo Cheng, Chao Ji, Chao Ji, Chao Ji, Ting Gong

    Published 2025-06-01
    “…This study aims to investigate the expression patterns and potential biological functions of ferroptosis-related genes in pemphigus, as well as their regulatory mechanisms.MethodsTo achieve this, skin samples from five pemphigus patients and five healthy controls were collected from Fujian Medical University Union Hospital. …”
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  17. 1777

    Assessing the prognostic and therapeutic value of cuproptosis-related genes in colon adenocarcinoma patients by Zhanhui Ye, Yixian Song, Mengqing Zhu, Fuying Zheng, Wenjie Qin, Wenjie Qin, Xue Li, Pei Wang, Zihua Li, Kequan Chen, Aimin Li

    Published 2025-04-01
    “…Using the Weighted Gene Co-expression Network Analysis (WGCNA) method, we identified the gene module most strongly linked to cuproptosis and conducted functional enrichment analysis to explore the roles of genes within this module in COAD tumorigenesis. …”
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  18. 1778
  19. 1779

    Identification and Expression Analysis of the Phospholipase D Gene Family in Rice by Huasheng CAO, Tang LI, Liang XIONG, Fujun WANG, Shuguang LI, Haiyong GU, Gao HE, Shihu LIANG, Wenyong LUO

    Published 2024-12-01
    “…【Objective】Phospholipase D (PLD) plays a crucial role in plant growth, development, and stress response. The study was conducted to explore the PLD gene family members involved in biotic and abiotic stress in rice (Oryza sativa L.) and investigate their biological functions.…”
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  20. 1780

    Helminth Coinfections Modulate Disease Dynamics and Vaccination Success in the Era of Emerging Infectious Diseases by Brice Armel Nembot Fogang, Linda Batsa Debrah, Michael Owusu, George Agyei, Julia Meyer, Jonathan Mawutor Gmanyami, Manuel Ritter, Kathrin Arndts, Derrick Adu Mensah, Tomabu Adjobimey, Achim Hörauf, Alexander Yaw Debrah

    Published 2025-04-01
    “…<b>Methods</b>: This systematic review conducted in line with the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020 guidelines synthesizes the current evidence, identifies patterns, and highlights areas needing further research, offering a cohesive understanding of the topic. …”
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