Expression characteristics, molecular mechanisms, and clinical significance of DICER1 in breast cancer by Xi Zhang, Long Yu, Cuizhi Geng

“…Weighted gene co-expression network analysis (WGCNA) was used to identify gene modules associated with the breast cancer phenotype, and gene set enrichment analysis (GSEA) was performed to explore their biological functions. Cellular experiments were conducted to verify the effects of DICER1 on the proliferation, migration, and invasion of breast cancer cells. …”
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Health-related quality of life, physical and mental capacity at one year follow up of COVID-19 ICU patients: A prospective cohort study by Anders Ersson, Henrik Överengen Reuterborg, Anestis Divanoglou, Richard Levi, Lotti Orwelius

“…Secondary outcome parameters were clinimetric results for physical, mental, and cognitive functions at 6 months after intensive care stay. Results Data from 41 patients were analyzed. …”
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Examining the effects of femoral anteversion and passive hip rotation on ACL injury and knee biomechanics: a systematic review and meta‐analysis by Jennifer A. Hogg, Justin P. Waxman, Sandra J. Shultz

“…Included studies were submitted to Downs & Black Quality Assessment Tool. Meta‐analyses were conducted for comparisons including at least two studies. …”
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Multi-omics network toxicology reveals the role of benzo[a]pyrene in ovarian cancer: Integrating gut microbiota dynamics and Mendelian randomization by Jinfa Huang, Qian Yang, Lingling Zeng, Kaixian Deng

“…Protein-protein interaction networks and functional enrichment analyses were conducted utilizing Cytoscape, while molecular docking (CB-Dock 2) confirmed a strong binding affinity between BaP and core targets (e.g., HSP90AA1: −11.7; AHR: −10.0). …”
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Biomarker Investigation Using Multiple Brain Measures from MRI Through Explainable Artificial Intelligence in Alzheimer’s Disease Classification by Davide Coluzzi, Valentina Bordin, Massimo W. Rivolta, Igor Fortel, Liang Zhan, Alex Leow, Giuseppe Baselli

“…Then, differences in explainability patterns between the two models were assessed to explore the insights offered by each piece of data (i.e., MRI vs. connectivity). …”
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Effects of DCM Leaf Extract of Gnidia glauca (Fresen) on Locomotor Activity, Anxiety, and Exploration-Like Behaviors in High-Fat Diet-Induced Obese Rats by Wycliffe Makori Arika, Cromwell Mwiti Kibiti, Joan Murugi Njagi, Mathew Piero Ngugi

“…Obesity is the main component of metabolic syndromes involving distinct etiologies that target different underlying behavioral and physiological functions within the brain structures and neuronal circuits. …”
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Correlation Between Peripheral Blood Immune Cell Distribution and Disease Severity and Prognosis in Multiple Sclerosis Patients by Liu PJ, Yuan P, Liu SP

“…Pen-Ju Liu, Peng Yuan, Shui-Ping Liu Department of Neurology, Beijing Anzhen Hospital, Capital Medical University, Beijing, 100029, People’s Republic of ChinaCorrespondence: Pen-Ju Liu, Department of Neurology, Beijing Anzhen Hospital, Capital Medical University, No. 2 Anzhen Road,Chaoyang District, Beijing, 100029, People’s Republic of China, Tel +86-13521678687, Email lpjhq@163.comObjective: This study aimed to examine the relationship between peripheral blood immune cell distribution patterns and both disease severity and prognosis in patients with multiple sclerosis (MS).Methods: We conducted a retrospective analysis of clinical data from MS patients admitted to the Neurology Department of our Hospital between March 2020 and April 2024. …”
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Genome-Wide Identification and Cold Stress Response Mechanism of Barley Di19 Gene Family by Wenbo Chai, Chao Yuan, Shufen Li, Hanyuan Xu, Qing Zhu, Hongtao Li, Wei Ji, Jun Wang

“…However, little is known about their roles in barley (<i>Hordeum vulgare</i>), particularly in cold stress adaptation. This study aimed to conduct a comprehensive genome-wide analysis of the barley genome to identify Di19 gene family members and examine their expression patterns under cold stress, providing theoretical support for stress-resistant barley breeding. …”
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The relationship between immune cell infiltration and necroptosis gene expression in sepsis: an analysis using single-cell transcriptomic data by Shouyi Wang

“…Differentially expressed genes (DEGs) were identified using the limma package, and functional enrichment analysis was performed using the clusterProfiler package for Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways. …”
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Developing generalized model representations of thermal shock for local non-equilibrium heat transfer processes by E. M. Kartashov

“…The purpose of such studies is to determine basic flux patterns of complex processes occurring especially under conditions of powerful energy impacts in various technological operations. …”
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Facilitators, barriers, and recommendations for mobile health applications among Chinese older populations: a scoping review by Wilson Kin Chung Leung, Connie Yim Ching Yau, Simon Ching Lam

“…Recommended interface designs were categorized into various aspects of functional impairments (vision, manual dexterity, and cognition) of elderly users. …”
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A megbékélés józsefi paradigmája by Sarolta PÜSÖK

“…The biblical stories carry timeless messages, behavioral patterns, archetypes which are worth analyzing so that evil cannot be repeated, to stop transmitting bad schemes and empower the functional ones through biblical examples. …”
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Multi-Domain Environmental Quality of Indoor Mixed-Use Open Spaces and Insights into Healthy Living—A Quarantine Hotel Case Study by Han Wang, Wenjian Pan

“…Many hotels adopt mixed-use and open room spatial layouts, integrating diverse daily functions into a single tiny space, fostering flexible utilization and micro-scale space sharing; however, these also introduce potential health risks. …”
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Bibliometric and visualization analysis of temporomandibular joint osteoarthritis from 2004 to 2024 by Chi Xu, Chi Xu, Chi Xu, Chongqing Yu, Chongqing Yu, Chongqing Yu, Tao Wang, Tao Wang, Tao Wang, Xiang Gao, Xiang Gao, Xiang Gao

“…BackgroundTemporomandibular joint osteoarthritis (TMJOA) is a severe condition affecting the temporomandibular joint, impairing essential oral functions such as chewing, speaking, and swallowing. …”
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Evolutionary insights and expression dynamics of the glutathione peroxidase (GPX) gene family in water lily (Nymphaea colorata) in response to multiple abiotic stresses by Wasi Ullah Khan, Latif Ullah Khan, Noor Muhammad Khan, Wang Wenquan, Fei Chen

“…The glutathione peroxidase (GPX) family in plants contains various isoenzymes, each with distinct subcellular localizations, tissue-specific expression patterns, and responses to environmental stress. In current study, we conducted genome-wide bioinformatics analyses of the GPX gene family in Nymphaea colorata, identifying five putative NcGPX genes dispersed across five of the fourteen chromosomes. …”
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Characterization and prognostic of CD8 + TIM3 + CD101 + T cells in glioblastoma multiforme by Hong-Liang Wang, Sai Li, Chun-Chun Ma, Xiang-Hu Zheng, Hao-Yuan Wu, Chen-Xi Chang, Zhi-Hao Yang, Jia-Wei Wang, Fa-Ming Pan, Bing Zhao

“…DEGs were identified, and cell trajectories were constructed using Seurat, Monocle 2, and CellChat packages. Functional enrichment analysis was conducted with clusterProfiler, and a prognostic model was developed. …”
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The effect of dual inflammation on the acute phase clinical outcomes of schizophrenia patients with comorbid COVID-19 by Jiahui Zhu, Jiamin Shao, Peng Wang, Yuan Liu, Gangming Cheng, Qi Zhou, Zhuoran Li, Jiayi Li, Mingqia Wang, Zhuokai Zhang, Xuan Dong, Chuan Shi

“…Then clinical symptoms, cognitive performance, and functional assessments were conducted at recruitment. …”
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Identification and validation of efferocytosis-related biomarkers for the diagnosis of metabolic dysfunction-associated steatohepatitis based on bioinformatics analysis and machine... by Chenghui Cao, Chenghui Cao, Wenwu Liu, Xin Guo, Shuwei Weng, Yang Chen, Yonghong Luo, Shuai Wang, Botao Zhu, Botao Zhu, Yuxuan Liu, Yuxuan Liu, Daoquan Peng

“…This analysis was followed by a series of in-depth investigations, including protein–protein interaction (PPI), correlation analysis, and functional enrichment analysis, to uncover the molecular interactions and pathways at play. …”
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Prediction of generalized anxiety disorder treatment outcomes with neurobehavioral responses to approach-avoidance conflict: a randomized clinical trial by Hannah Berg, Timothy J. McDermott, Rayus Kuplicki, Hung-Wen Yeh, Wesley K. Thompson, Ryan Smith, Elisabeth Akeman, Namik Kirlic, Ashley Clausen, Mallory Cannon, Evan White, Christopher R. Martell, Kate B. Wolitzky-Taylor, Michelle G. Craske, James L. Abelson, Martin P. Paulus, Robin L. Aupperle

“…Participants completed an AAC task during functional magnetic resonance imaging pre-treatment. …”
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Deep-Learning-Based Land Cover Mapping in Franciacorta Wine Growing Area by Girma Tariku, Isabella Ghiglieno, Andres Sanchez Morchio, Luca Facciano, Celine Birolleau, Anna Simonetto, Ivan Serina, Gianni Gilioli

“…Land cover mapping is essential to understanding global land-use patterns and studying biodiversity composition and the functioning of eco-systems. …”
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