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1561
An FPGA-Based SiNW-FET Biosensing System for Real-Time Viral Detection: Hardware Amplification and 1D CNN for Adaptive Noise Reduction
Published 2025-01-01“…Notably, the findings presented in this work are based exclusively on comprehensive simulations using COMSOL and MATLAB, as no physical prototypes or biomarker detection experiments were conducted. The SiNW-FET biosensor, functionalized with antibodies specific to viral antigens, detects impedance shifts caused by antibody–antigen interactions, providing a highly sensitive platform for viral detection. …”
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1562
Deep learning-guided structural analysis of a novel bacteriophage KPP105 against multidrug-resistant Klebsiella pneumoniae
Published 2025-01-01“…Structure-based functional analysis provided comprehensive insights into cell wall degradation with various peptidoglycan fragments. …”
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1563
Systematic review of the use and challenges of electronic health records in physiotherapy practice
Published 2025-07-01“…Objective To synthesise current evidence on physiotherapists’ use of electronic health records (EHRs), with a focus on the determinants of adoption, implementation processes and associated implementation outcomes.Design A systematic review employing a narrative synthesis approach.Data sources PubMed, Cochrane, Scopus and Web of Science, covering all records from the inception of each database to 10 May 2024.Eligibility criteria Studies conducted in physiotherapy clinical settings and using the International Classification of Functioning, Disability and Health (ICF).Data extraction and synthesis Two authors independently screened articles and assessed methodological quality. …”
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1564
Consumption of only wild foods induces large scale, partially persistent alterations to the gut microbiome
Published 2025-05-01“…Samples were profiled by 16S rRNA sequencing, and oligotyping and network analysis were conducted to assess microbial co-occurrence patterns. …”
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1565
Exploring Work Engagement and Cynicism in Industry: A Preliminary Investigation in a Central Italian Engineering Company
Published 2025-04-01“…The results emphasize the need to expand the sample and to conduct comparative analyses across different teams within the company better understand engagement patterns and inform targeted interventions. …”
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1566
De Novo Synthesis of Anticholinergic Hyoscyamine and Scopolamine in <i>Nicotiana benthamiana</i> Based on Elucidating Tropane Alkaloid Biosynthetic Pathway of <i>Anisodus luridus</...
Published 2024-10-01“…Its high yield of hyoscyamine makes <i>A. luridus</i> a valuable plant source for commercially producing TAs. In this study, we conduct homologous gene research across transcriptome data of different tissues together with functionally tested sequences in <i>Atropa belladonna</i> as a reference and identify 13 candidate genes for TAs biosynthesis in <i>A. luridus</i>. …”
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1567
SMARCB1 orchestrates cellular plasticity and oncogenic pathways in typical and chondroid chordomas
Published 2025-06-01“…This study examined 42 chordoma samples (26 typical, 16 chondroid) for SMARCB1 genetic alterations, expression patterns, and associated pathways. SMARCB1 knockdown experiments were conducted in chordoma cell lines, followed by comprehensive transcriptome analysis. …”
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1568
Design and Experimentation of a Height-Adjustable Management Platform for Pineapple Fields
Published 2025-06-01“…To address the challenges of inadequate adaptability, insufficient power, high ground clearance, and limited functionality in existing pineapple field machinery, this study proposes a height-adjustable pineapple field management platform based on previously established cultivation patterns and agronomic requirements. …”
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1569
The impact of phthalates on asthma and chronic obstructive pulmonary disease: a comprehensive analysis based on network toxicology and molecular docking
Published 2025-03-01“…By integrating information from multiple databases, we identified key target genes linked to these compounds and conducted functional enrichment analyses to elucidate their roles in pathological processes.ResultsOur results demonstrate that these phthalates affect the pathogenesis of asthma and COPD by modulating various target genes, including PTGS2, MMP9, and CASP3, which are involved in essential biological pathways such as apoptosis and immune response. …”
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1570
Traditional Agroforestry Models Based on Local Knowledge in the Mount Mutis-Timau Highlands,Timor Island, Indonesia
Published 2025-02-01“…Data were collected through a series of systematic stages, including indepth interviews with respondents who were heads of households and community leaders, direct observation of the land, and literature studies related to agroforestry patterns. A descriptive analysis using a qualitative approach was conducted to obtain important information regarding the actual conditions observed. …”
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1571
Genome-Wide Identification of the GRAS Transcription Factor Family in <i>Medicago ruthenica</i> and Expression Analysis Under Drought Stress
Published 2025-01-01“…Overall, this study analyzed the phylogenetic relationships, conserved domains, <i>cis</i>-regulatory elements and expression patterns of the <i>GRAS</i> gene family in <i>M. ruthenica</i>, filling the gap in the identification of the <i>MrGRAS</i> gene family and laying the foundation for functional analysis of the <i>MrGRAS</i> gene family.…”
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1572
Local haplotyping reveals insights into the genetic control of flowering time variation in wild and domesticated soybean
Published 2024-12-01“…These findings support future functional validation of haplotype‐based alleles for marker‐assisted breeding and genomic selection to enhance latitude adaptability of soybean without compromising yield.…”
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1573
XPO1 serves as a prognostic marker involving AKT/MAPK/TGFBR1 pathway in OSCC
Published 2024-08-01“…Survival analysis was conducted to evaluate the impact of XPO1 on prognosis. …”
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1574
Placental Vimentin Expression in Preeclampsia and Gestational Diabetes Mellitus
Published 2024-04-01“…CONCLUSION: Vimentin expression patterns in placental tissue sections reveal nuanced regulatory mechanisms, emphasizing the need for further exploration into the functional roles of vimentin in placental physiology and pathology. …”
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1575
The impact of Alzheimer's disease on cortical complexity and its underlying biological mechanisms
Published 2025-06-01“…In addition, transcription–neuroimaging association analyses, as well as Mendelian randomization of AD and cortical thickness data, were conducted to investigate the genetic mechanisms and biological functions of AD. …”
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1576
Recursive Class Connectivity Classification (R3C) Applied to Binary Image Segmentation for Improved Infant Fingerprint Enhancement
Published 2025-01-01“…A qualitative analysis further demonstrates that R3C reconnects fragmented ridge patterns, improving the visual quality of segmentation. …”
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1577
Site-specific immunoglobulin G N-glycosylation is associated with gastric cancer progression
Published 2025-02-01“…Analysis of key glycogenes revealed differential expression patterns, implicating a functional role for IgG N-glycosylation in GC. …”
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1578
Linguistic Representation of Women in Balochi Proverbial Discourse: A Feminist Critical Discourse Analysis
Published 2024-09-01“…By analyzing the discursive practices embedded in Balochi proverbs, this research elucidates the ways in which language functions as a medium for reinforcing asymmetrical power relations. …”
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1579
The development of the Polish version of the Compassionate Engagement and Action Scales.
Published 2025-01-01“…For compassion motivation stimulus sensitivity focuses on the processing of indicators of suffering, distress and need, called engagement. The response functions switch attention and processing to what is likely to be helpful in alleviating suffering, distress and need, called action. …”
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1580
Optimizing HVAC energy efficiency in low-energy buildings: a comparative analysis of reinforcement learning control strategies under Tehran climate conditions
Published 2025-01-01“…Model B consisted of a deep convolutional network architecture with 256 neurons in each hidden layer, employing rectified linear units as activation functions and the Adam optimizer at a learning rate of 0.001. …”
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