Unveiling the tissue-specific landscape of nuclear-encoded mitochondrial genes involved in amino acid  metabolism in buffalo by E. M. Sadeesh, Madhuri S. Lahamge

“…Abstract Mitochondria play a pivotal role in energy production, metabolism, and cellular signaling, serving as key regulators of cellular functions, including differentiation and tissue-specific adaptation. …”
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Identification and validation of hub m7G-related genes and infiltrating immune cells in osteoarthritis based on integrated computational and bioinformatics analysis by Zhenhui Huo, Chongyi Fan, Kehan Li, Chenyue Xu, Yingzhen Niu, Fei Wang

“…Immune cell infiltration was analyzed using the CIBERSORT algorithm, and unsupervised clustering analysis was conducted to examine immune infiltration patterns. …”
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Dietary supplementation with L-carnitine elevates intracellular carnitine levels and affects gene expression of SLC25A20 and COX4I1, as well as non-mitochondrial respiration of bov... by Leonie Seemann, Susanne Kersten, Susanne Bühler, Fabian Billenkamp, Ulrich Meyer, Christian Visscher, Korinna Huber, Erika Most, Klaus Eder, Sven Dänicke, Jana Frahm

“…The same applied for PBMC mitochondrial functionality and metabolic activity as assessed by ex vivo approaches, whereas non-mitochondrial respiration rate was significantly affected by L-carnitine supplementation over time. …”
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Age-related changes in brain signal variability in autism spectrum disorder by Priyanka Sigar, Nicholas Kathrein, Elijah Gragas, Lauren Kupis, Lucina Q. Uddin, Jason S. Nomi

“…Conclusion These findings highlight age-related atypical BSV patterns in ASD and their association with repetitive behaviors, contributing to the growing literature on understanding alterations in functional brain maturation in ASD.…”
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Clinical Outcomes in Non Valvular Atrial Fibrillation Patients Receiving Oral Anticoagulation Therapy using CHA2DS2-VASc and HAS-BLED Scores: A Cohort Study from Western Gujarat, I... by Sohilkhan Riyazkhan Pathan, Bharat M Gajjar, Sunilkumar Karna, Kushal Pujara

“…The Cochrane-Armitage trend test evaluated anticoagulant use patterns. A p-value <0.05 was considered statistically significant. …”
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Photosynthetic response of Solidago gigantea Aition and Calamagrostis epigejos L. (Roth) to complex environmental stress on heavy metal contaminated sites by Wojciech Bąba, Agnieszka Kompała-Bąba, Edyta Sierka, Wojciech Bierza

“…Abstract Studies of in situ plant response and adaptation to complex environmental stresses, are crucial for understanding the mechanisms of formation and functioning of ecosystems of anthropogenically transformed habitats. …”
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The revival of the electrocardiogram in the stress imaging era: what European Society of Cardiology 2024 guidelines say (and don’t say) by Emma Cerracchio, Ettore Campagnano, Bruno Villari, Quirino Ciampi

“…An ECG continuously monitors the heart’s electrical signals, capturing data on heart rate, rhythm, and electrical conduction patterns. The value of the ECG in this context lies in its ability to detect ischemic changes, which occur when there is insufficient blood flow to the heart muscle due to narrowed or blocked coronary arteries, but also for coronary vasospasm or coronary microvascular disease. …”
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The Impact of Paragliding on Human Health - Literature Review by Maksymilian Wiśniowski, Klaudia Kulig, Kacper Buczek, Michal Popiel, Kamil Dziekoński, Ada Wiśniowska, Aneta Redner, Julia Głowacz, Dominik Stanibuła, Patrycja Zwierzchlewska, Kamila Smala

“…Research materials and methods: A systematic review was conducted using PubMed, ResearchGate, and Google Scholar. …”
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Single-Nucleus RNA Sequencing Reveals Muscle-Region-Specific Differences in Fibro-Adipogenic Progenitors Driving Intramuscular Fat Accumulation by Shuji Ueda, Chiaki Kitamura, Yuka Tateoka, Akinori Kanai, Yutaka Suzuki, Itsuko Fukuda, Yasuhito Shirai

“…Results: Distinct gene expression patterns were observed among the different muscles. …”
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YWHAG promotes bladder cancer metastasis by regulating TMOD3 to activate ERK1/2 and JNK phosphorylation in the MAPK pathway by Tai Tian, Shiming He, Han Hao, Bao Guan, Yanqing Gong, Jian Fan, Zhenpeng Zhu, Wenzhi Gao, Yucai Wu, Ninghan Feng, Aixiang Wang, Yuexian Guo, Xuesong Li

“…The functional role of YWHAG in bladder cancer progression was examined through a series of in vitro and in vivo experiments. …”
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Toll-like receptor 3 activation enhances antitumor immune response in lung adenocarcinoma through NF-κB signaling pathway by Ang Li, Ang Li, Ang Li, Man Luo, Xiyao Liu, Hongjiao Wu, Hongjiao Wu, Hongjiao Wu, Xiaoguang Liu, Zhi Zhang, Xuemei Zhang, Xuemei Zhang, Xuemei Zhang

“…BackgroundToll-like receptor 3 (TLR3) is a pattern recognition receptor known to play a crucial role in the immune response to cancer. …”
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Anticancer activity of RM-3-22: a TAZQ-based hydroxamic acid derivative targeting NSCLC in vitro and in vivo by Essha Chatterjee, Essha Chatterjee, Ram Sharma, Biswajit Dey, Biswajit Dey, Hoshiyar Singh, Aliva Naik, Anjesh Khan, Santanu Basak, Ankush Bansode, Ritika Sachdeva, Anamika Sharma, Rahul Kumar, Pradeep Naik, Pankaj Kumar Singh, Kunal Nepali, Santosh Kumar Guru

“…Different in silico studies were also conducted to check the clinical relevance and expression pattern of the RM-3-22-induced gene. …”
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Effectiveness of Cognitive Behavioral Therapy in Managing Painful Temporomandibular Joint Disorders -A Systematic Review of Randomized Clinical Studies by Ravleen Nagi, Vikranth Ravipati, Radhika Thakkar, Maryam Altuhafy, Shehla F. Hashmi, Junad Khan

“…One study reported that CBT might enhance function recovery in myofascial pain patients with limited opening and posture correction.Conclusion The study analysis suggested CBT may reduce damaging thought patterns and cognitive difficulties and be used with the standard treatment of TMDs. …”
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FACTORS ASSOCIATED WITH ANXIETY AND DEPRESSION SPECTRUM DISORDERS IN BEHCHET’S DISEASE by P. S. Ovcharov, T. A. Lisitsyna, D. Yu. Veltishchev, O. F. Seravina, O. B. Kovalevskaya, S. I. Glukhova, Z. S. Alekberova, E. L. Nasonov

“…Sleep disorders, asthenic syndrome, and CI are significant in the pattern of ADSDs.…”
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Pan-cancer analysis reveals dual roles of HES6 in cancer immunity and prognosis by Ying Sun, Peiru Liu, Dongyang Lv, Defu Yang, Shiyu Qiao, Jing Liu, Ying Yan, Wenping Wang

“…Abstract A comprehensive pan-cancer analysis of HES6 was conducted to investigate the differential expression patterns, clinical implications, and prognostic significance of HES6 across multiple cancer types, while also aiming to elucidate the underlying biological mechanisms of HES6 in oncogenesis. …”
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Harnessing the diversity of a lettuce wild relative to identify anthocyanin-related genes transcriptionally responsive to drought stress by Inés Medina-Lozano, Inés Medina-Lozano, Jérôme Grimplet, Jérôme Grimplet, Aurora Díaz, Aurora Díaz

“…A transcriptomic study in the variety ‘Romired’ and the wild relative Lactuca homblei was conducted to understand the increase in anthocyanins (only significant in L. homblei) in response to drought previously observed. …”
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Bivariate Frequency Analysis of Extreme Sea Level with Rainfall and Temperature in New York City by Ali Razmi, Emad Mahjoobi, Heydar Ali Mardani-Fard, Zahra Zahmatkesh

“…Climate change negatively impacts hydrologic patterns, affecting rainfall, temperature extremes, and sea level rise. …”
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Prognostic Potential of AKR1B1 in triple-negative breast cancer by Xiong Jing, Liao Xinghua, Liu Yimeng, Wang Jincheng, Fu Yufeng, Jiang Shu, Guo Hongshan

“…This research conducts a thorough bioinformatics examination to explore the possible function of Aldose Reductase (AKR1B1) in Triple - Negative Breast Cancer (TNBC). …”
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Genome-Wide Identification of the <i>GS3</i> Gene Family and the Influence of Natural Variations in <i>BnGS3-3</i> on Salt and Cold Stress Tolerance in <i>Brassica napus</i> by Ting Jin, Xiaoshuai Hao, Zhen Huang, Xingguo Zhang, Shimeng Li, Ying Yang, Weihua Long

“…In this study, we employed bioinformatics tools to systematically investigate the basic physicochemical properties, phylogenetic relationships, distribution, gene structure, cis-regulatory elements, and expansion patterns of the <i>GS3</i> gene family in <i>Brassica napus</i>. …”
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The Cosmic Evolution and Spatial Distribution of Multiphase Gas Associated with QSOs by Zeyu Chen, Enci Wang, Hu Zou, Haoran Yu, Zhicheng He, Huiyuan Wang, Yang Gao, Cheqiu Lyu, Cheng Jia, Chengyu Ma, Weiyu Ding, Runyu Zhu, Xu Kong

“…We also find that W _FeII / W _MgII increases toward lower redshifts, which can be attributed to evolving star formation histories and/or changes in initial mass function for galaxies. By leveraging multiple absorption tracers, we conduct the first comprehensive investigation of diffuse, multiphase gas from the circumgalactic medium to cosmological scales, offering new insights into baryon cycles and the transport of metals throughout cosmic time.…”
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