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1721
Genomic and Transcriptomic Analysis to Explore the Biological Characteristics of <i>Cyclocybe chaxingu</i>
Published 2025-04-01“…Transcriptomic analysis revealed distinct gene expression patterns in mycelia, stipe, and cap, reflecting their functional specialization. …”
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1722
Effect of Chlorhexidine and Benincasa Hispida Pretreatment on Microshear Bond Strength of Universal Adhesive System on Dentin: A Pilot Study
Published 2024-11-01“…The MSBS to dentin was evaluated using a universal testing machine. The failure patterns were analysed using a stereomicroscope at 10x magnification. …”
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1723
Arthroscopic all-inside ACL reconstruction with anterolateral tendon fixation: a prospective cohort study on restoring rotational stability in high-grade tibial shift
Published 2025-07-01“…Early outcomes demonstrate promising functional recovery and objective stability at short-term follow-up, suggesting that this technique may offer biomechanical benefits for managing severe instability patterns. …”
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1724
New biomarkers of Kawasaki disease identified by gingival crevicular fluid proteomics
Published 2025-05-01“…DEPs were identified and subjected to functional enrichment analysis using KEGG and GO. Protein–protein interaction (PPI) analysis was conducted for all detected DEPs. …”
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1725
Constitutive model of metal rubber material considering plastic accumulation behavior
Published 2025-01-01“…Due to the complex and varied interlocking patterns of internal metallic helical coils during cold compression molding, residual stresses typically exist after forming. …”
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1726
Impact assessment of differential chlormequat chloride exposure on soil fungal community dynamics
Published 2025-07-01“…The significant shifts observed in key functional guilds, particularly the decline in pathogens and proliferation of saprophytes, highlight the impact of CC application on soil fungal ecological functions.…”
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1727
Genome-Wide Identification and Expression Analysis of <i>NAC</i> Gene Family Members in Seashore Paspalum Under Salt Stress
Published 2024-12-01“…The transcriptomic analysis investigates the expression patterns of <i>NAC</i> genes in both leaves and roots under varying durations of salt stress. …”
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1728
A novel NFKB1 agonist remodels tumor microenvironment and activates dendritic cells to promote anti-tumor immunity in colorectal cancer
Published 2025-05-01“…An in vitro co-culture system was applied to establish that the damage-associated molecular patterns (DAMPs) released by the tumor cells are accountable for the activation of dendritic cells (DCs). …”
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1729
Dynamics of cerebral blood flow following sertraline treatment in adolescent depression
Published 2025-07-01“…Among the depressed cohort, 25 participants adhered to the treatment protocol and completed MRI scans. Resting-state functional MRI (rs-fMRI) scans were conducted for all participants, with a subsequent scan for the depression group after 8 weeks of sertraline therapy. …”
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1730
Navigating Nepal's health financing system: A road to universal health coverage amid epidemiological and demographic transitions.
Published 2025-01-01“…Policies and content related to the health financing system were reviewed to understand the status, issues and challenges of health financing functions, and UHC . A framework-guided deductive content analysis approach was employed, and findings were interpreted using the three UHC components: service coverage, population coverage, and financial coverage.…”
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1731
Identification and Mechanistic Studies of Key Genes in Thalamic Hemorrhage Pain by Multi-omics
Published 2025-07-01“…Intercellular communication networks and lineage progression patterns of these cells were systematically characterized, alongside spatial and temporal expression profiles of key genes. …”
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1732
The novel diagnostic markers for systemic lupus erythematosus and periodontal disease
Published 2025-07-01“…Protein-protein interaction (PPI) network analysis was conducted to explore relationships between hub genes. …”
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1733
Identification of DNA Methylation Differences in Pituitary Tissues of Sichuan White Geese Using Whole-Genome Bisulfite Sequencing (WGBS)
Published 2025-02-01“…Integrated GO and KEGG enrichment analysis conducted to explore the role of regulatory networks of epigenetic modification on egg-laying traits in Sichuan White geese identified multiple metabolic pathways associated with egg-laying traits (promoting egg transport, ovulation, and yolk protein synthesis and secretion), thus providing a basis for subsequent functional verification.…”
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1734
SMYD2 epigenetically activates BMP4/SMAD1/5/8/ID3 axis to enhance cancer stem cell properties and drive sorafenib resistance in hepatocellular carcinoma
Published 2025-09-01“…To investigate the biological functions of SMYD2, we conducted a series of functional assays in vitro and in vivo. …”
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1735
NAP1L5 in acute myeloid leukemia: a prognostic biomarker and potential therapeutic target
Published 2025-07-01“…To elucidate the functional role of NAP1L5, we conducted Gene Set Enrichment Analysis (GSEA) and Gene Ontology (GO) analysis, which revealed its involvement in specific signaling pathways and biological processes. …”
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1736
The Role of Values and Emotions in Accepting Fake Political News in the Post-Truth Era
Published 2024-12-01“…The interview data were analyzed using Discursive Psychology, focusing on the linguistic patterns and discourse structures in the participants' responses. …”
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1737
The Jojosi Dongas: An interdisciplinary project to study the evolution of human behaviour and landscapes in open-air contexts
Published 2024-05-01“…The remains left behind at such sites allow for unique archaeological insights into the spatial patterning of prehistoric behaviour. The Stone Age record in southern Africa remains best-known from sheltered sites. …”
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1738
Identification and validation of efferocytosis-related biomarkers for the diagnosis of metabolic dysfunction-associated steatohepatitis based on bioinformatics analysis and machine...
Published 2024-10-01“…Thus, we aimed to identify and validate efferocytosis linked signatures for detection of MASH.MethodsWe retrieved gene expression patterns of MASH from the GEO database and then focused on assessing the differential expression of efferocytosis-related genes (EFRGs) between MASH and control groups. …”
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1739
In-vitro transcriptomic profiling of indigenous Gaddi vis-à-vis exotic Labrador dogs: insights from systems biology
Published 2025-06-01“…Gaddi dogs had unique miRNAs (miR-551 and miR-1249) associated with tumor suppression and inflammation.DiscussionThe study highlights distinct immunological profiles between Labrador and Gaddi dogs, with no shared genes responding to TLR-ligand stimulation. The functional enrichment of miRNA targets demonstrated consistent regulatory patterns at both the mRNA and miRNA levels. …”
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1740
Opportunities for immunocorrection aiming for reduction of morbidity in the areas with adverse occupational and environmental conditions
Published 2021-01-01“…The patients with a detected decrease in cellular immunity received immunotropic drugs based on alpha-glutamyl-tryptophan (Thymogen nasal spray dosed (Thymogen, 62 persons), or combined encapsuleted Cytovir-3 drug (Cytovir, 31 cases). 14 days after finishing the course, a second immunological study was conducted. Following the immunotropic therapies, the subjects showed an increase in relative content of CD3+, CD4+, and CD8+ subpopulations, normalization of functional oxygen-dependent metabolism of polymorphonuclear neutrophil granulocyte system in the NBT test, as well as harmonization of the content of serum immunoglobulin contents. …”
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