Performance exploration of multi-gene panels of alopecia areata susceptibility and drug-binding targets by Hongye Liu, Yang Li, Ling Ren, Xiaofeng Yang, Shuo Zhang, Hongmei Bi, Hongxia He, Jingyu Ren, Xiaoqing Lang, Shuping Guo

“…ObjectiveThis study aims to identify potential target genes and therapeutic drugs for alopecia areata (AA).MethodsUtilizing training and testing data, we evaluated multi-gene panels derived from commonly upregulated genes in publicly available AA patient datasets. The functions of these genes in biological processes were analyzed to identify special multi-gene panels that may play crucial roles in AA. …”
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Genome-wide identification and characterization of the CCT gene family in Chinese cabbage (Brassica rapa) response to abiotic stress by Haoqi Liu, Zhiyuan Yin, Mengping Qiu, Yan Yang, Ye Xu, Han Wang, Min Yan, Guohua Xu

“…Results In this study, we conducted a genome-wide identification and analysis ofCCT genes in Chinese cabbage. …”
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How topographic factors regulate vegetation vigor in reservoir drawdown zones with different levels of hydrological disturbances? by Xu Zhou, Zhaofei Wen, Shengjun Wu

“…Topography plays a fundamental role in shaping vegetation distribution, community structure, and ecosystem functioning. This influence remains significant in hydrologically complex environments, particularly in reservoir drawdown zones (RDZs). …”
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Pelagic fish camouflage in shallow waters from the humboldt current system through intracellular structures and reflectance mechanisms by Caroline S. Montes, Ricardo F. Soto, Mario I. Sanhueza, Ignacio Sanhueza, Danny Luarte, Sebastián E. Godoy, Sergio N. Torres, Rosario Castillo, Rubén Escribano, Mauricio A. Urbina

“…These Scanning Electron Microscopy (SEM) images were analyzed using the 2D discrete Fourier transform to extract the spatial patterns that govern the light interaction with the guanine crystal structures. …”
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Genome-wide identification and expression profile analysis of TALE superfamily genes under hormone and abiotic stress in maize (Zea may L.) by Peiyan Guan, Dongbo Zhao, Longxue Wei, Peipei Cui, Shicai Zhang

“…These results can lay the foundation for analysis of the functions of ZmTALE genes under ABA and abiotic stresses.…”
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Strength-agility and fine motor are differently associated with non-verbal intelligence in dependency to sex and age in school children: Structural equation modelling multigroup ap... by Martin Musálek, Chipo Malambo, Jan Chrudimský, Jakub Kokštejn, Radka Bačáková, Šárka Vokounová

“…While motor proficiency has been positively linked to various cognitive functions in children, its relationship with nonverbal Intelligence remains an open question. …”
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Genome-wide identification, expression analysis, and response to abiotic stress of the phosphate transporter gene family in cucumber (Cucumis sativus L.) by Kunhao Xie, Mintao Sun, Xiaoqin Wang, Xiaoya Zhou, Qinghua Di, Yang Li, Guoxiu Wu, Yansu Li, Chaoxing He, Shengli Li

“…Conclusion This study conducted a systematic analysis of the CsPHT gene family, which provides a theoretical foundation and candidate genes for subsequent functional characterization and the genetic improvement of abiotic stress tolerance in cucumber.…”
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Integrated genomic and transcriptomic analysis of polydactyly in chickens by Zhiying Huang, Xiaomeng Miao, Diyan Li, Jia Liu, Haolin Chen, Yuan Su, Yuan Su

“…These findings offer clear targets for functional validation and may guide selective breeding for limb traits in poultry.…”
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Insights into the blood, gut, and oral microbiomes in Chinese patients with myocardial infarction: a case-control study by Ikram Khan, Imran Khan, Ping Xie, Yu Xiaohui, Shengnan Lei, Tianzhu Song, Zhiqiang Li, Xiaodong Xie

“…Differential analyses were conducted to find key differential microbiota for MI. …”
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Single-cell technology reveals the crosstalk between tumor cells and immune cells: driving immune signal transduction and inflammation-mediated cardiac dysfunction in the tumor mic... by Wenyang Nie, Wangzheqi Zhang, Zhikai Xiahou, Yuxuan Meng, Yuhang Liu, Jingwen Zhang, Zhen Wang, Yong Wang

“…The cancer model utilizing the MKI67+ TCs subpopulation (MTRS) successfully classified patient survival and linked with immune infiltration patterns and medication responses. Enrichment analysis revealed tumor-promoting and immunological signaling networks. …”
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Patient experience in retinitis pigmentosa and Choroideremia– a concept elicitation study in 17 patients based on qualitative interviews by Elke Rometsch, Per-Olof Thuresson, Noémie Hurst, Eckhart Eule, Isabel Bachmeier, Benoit Blanchard, José-Alain Sahel, Isabelle Audo

“…Despite different underlying genetic pathways, they have many progression patterns in common, first affecting the more peripheral retina and later advancing toward the central retina. …”
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Clinical characteristics of obsessive-compulsive disorder comorbid with obsessive -compulsive personality disorder: subtype implications by Ayse Dondu, Levent Sevincok

“…However, the clinical relevance of this comorbidity remains uncertain, particularly in terms of whether it reflects a distinct OCD subtype characterized by specific onset patterns and symptom dimensions. The present study aimed to examine whether OCD patients with and without comorbid OCPD differ in terms of age and mode of onset, as well as the content of obsessive-compulsive (OC) symptoms. …”
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Mechanistic study of CTHRC1 in promoting Wilms’ tumor progression by regulating M2-type tumor-associated macrophages polarization by Yingquan Zhuo, Xiaoyun Feng, Wenqi Zhang, Jun Du, Xu Sun, Xi Luo, Wei Wang, Hua Jiang, Huajian Gu

“…Single-cell sequencing was employed to analyze expression patterns of CTHRC1 and M2-TAMs markers. CTHRC1 expression and M2-TAM infiltration were validated in WT tissues using RT-qPCR, Western blot, immunohistochemistry, and immunofluorescence. …”
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Meta-analysis of muscle transcriptome data identifies key genes influencing intramuscular fat content in pigs by Yan Wang, Jiahao Wang, Yanhui Zhao, Xihui Sheng, Xiaolong Qi, Lei Zhou, Jianfeng Liu, Chuduan Wang, Jianliang Wu, Yongchun Cao, Kai Xing

“…To identify key genes affecting IMF content, we performed a meta-analysis of the differential expression results from the 10 datasets using MetaVolcanoR. Subsequently, we conducted protein-protein interaction network analysis, Gene Ontology and Kyoto encyclopedia of genes and genomes functional enrichment analysis, and quantitative trait locus (QTL) analysis on the DEGs. …”
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Integrated Cytological, Physiological, and Comparative Transcriptome Profiling Analysis of the Male Sterility Mechanism of ‘Xinli No.7’ <i>Pear</i> (<i>Pyrus</i> sp.) by Hao Li, Xiangyü Li, Yüjia Luo, Quanhui Ma, Zhi Luo, Jiayuan Xuan, Cuiyun Wu, Fenfen Yan

“…Comparative transcriptomics identified 283 co-expressed differentially expressed genes (DEGs). Functional enrichment linked these DEGs to ROS-scavenging pathways: galactose metabolism, ascorbate and aldarate metabolism, arginine and proline metabolism, fatty acid degradation, pyruvate metabolism, and flavonoid biosynthesis. qRT-PCR validated the expression patterns of key DEGs in these pathways. …”
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Row configuration affects plant growth and grain yield of drip-irrigated maize-soybean strip intercropping system by regulating photosynthetic capacity and grain filling process by Hongtai Kou, Zhenqi Liao, Yiyao Liu, Zhenlin Lai, Zhijun Li, Junliang Fan

“…A two-year field experiment (2022 and 2023) was conducted on drip-irrigated maize and soybean in the Hexi Region of China with eight maize-soybean intercropping patterns and two monocropping maize/soybean controls, so as to explore the photosynthesis, fluorescence, chlorophyll formation, dry matter accumulation, nitrogen uptake, grain filling, grain water content, and grain yield of maize-soybean intercropping systems. …”
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The m6A modification of LINC01133 suppresses ER+ breast cancer progression by modulating IGF2BP2 protein stability via a ubiquitination-dependent mechanism by Mai-dong Li, Mai-dong Li, Ben-jie Shan, Lei Wang, Shuang Gao, Li Hao, Hai-yang Yu, Yue-yin Pan, Yue-yin Pan

“…Functionally, LINC01133 inhibited migration and invasion in vitro and metastasis in vivo of ER+ breast cancer cells. …”
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Effectiveness and cost-effectiveness of a structured integrated post-pulmonary embolism follow-up care model (Attend-PE): a rationale and protocol for a multicentre clinical pre-po... by Thomas Kümler, Søren Paaske Johnsen, Anette Arbjerg Højen, Erik Lerkevang Grove, Frederikus A Klok, Bettina Wulff Risør, Stavros Konstantinides, Jan Brink Valentin, Nanna Rolving, Stine Foged Lindegaard

“…Introduction Patients with pulmonary embolism (PE) experience impaired functional ability and reduced quality of life long after discharge from the hospital. …”
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Age-Related Changes in Action Observation EEG Response and Its Effect on BCI Performance by Fukang Zeng, Xingyu Wen, Hongmei Tang, Guiyu Hu, Wensheng Hou, Xin Zhang

“…We employed task discriminant component analysis (TDCA) to decode observed actions and performed comprehensive analyses of prefrontal EEG responses, i.e. approximate entropy (ApEn), sample entropy (SamEn), and rhythm power ratios (RPR), and the whole-brain functional network. Regression analyses were subsequently conducted to analyze the effects on the classification accuracy. …”
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Transcriptomic analysis of mammary gland tissues in lactating and non-lactating dairy goats reveals miRNA-mediated regulation of lactation, involution, and remodeling by Yanan Peng, Xinhua Duan, Linfan Zhang, Yiyi Guo, Jinlin Cao, Weiping Ao, Rong Xuan

“…Differential expression analysis, miRNA clustering, Gene Ontology (GO) annotation, and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment were performed to predict the functions of target genes. A miRNA-mRNA regulatory network associated with mammary gland development was constructed, and functional validation experiments were conducted to confirm key regulatory relationships.ResultsA total of 1,120 miRNAs were identified, including 408 known and 712 newly predicted miRNAs. …”
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