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  1. 1661

    Immune intrinsic escape signature stratifies prognosis, characterizes the tumor immune microenvironment, and identifies tumorigenic PPP1R8 in glioblastoma multiforme patients by Ran Du, Lijun Jing, Denggang Fu

    Published 2025-08-01
    “…TIME analysis was carried out using multiple deconvolution algorithms. Additionally, functional assays including CCK8, cell cycle, and apoptosis assays were conducted on PPP1R8-silenced U251 cells using CRISPR/Cas9 technologyResultsThirty-six IERGs were associated with GBM outcomes, with 20 linked to poor survival and 16 to better outcomes. …”
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  2. 1662

    Retinol and Hydroxyasiaticoside Synergistically Relieve Histamine-Induced Atopic Dermatitis Activity by Repressing TRPV1, L1R1, and CD130 Targets by Qin Liu, Peng Shu, Qingle Song, Zhenhai Huang, Jiyu Weng, Lanyue Zhang, Yuan Wang, Qingqing Liu

    Published 2024-11-01
    “…Quantitative RNA-seq analysis revealed that the gene expression patterns were similar in different concentration groups. …”
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  3. 1663

    ENHANCEMENT OF SENSOR PANEL TACTILE TOUCH INTERFACE by Oleksandr Karpin, Zinovii Liubun, Vasyl Mandziy, Oleh Tereshchuk, Nestor Hotsiy

    Published 2025-03-01
    “…The neural network is designed to learn the patterns and characteristics of the signals, allowing it to accurately classify new, unseen signals. …”
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  4. 1664

    Exploring potential methylation markers for ovarian cancer from cervical scraping samples by Ju-Yin Lien, Lu Ann Hii, Po-Hsuan Su, Lin-Yu Chen, Kuo-Chang Wen, Hung-Cheng Lai, Yu-Chao Wang

    Published 2025-05-01
    “…Furthermore, an over-representation analysis was conducted to explore the functions associated with genes mapped from differentially methylated positions (DMPs) in comparisons between normal and tumor samples, as well as between benign and malignant samples. …”
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  5. 1665

    Decoding per- and polyfluoroalkyl substances (PFAS) in hepatocellular carcinoma: a multi-omics and computational toxicology approach by Yanggang Hong, Deqi Wang, Zeyu Liu, Yuxin Chen, Yi Wang, Jiajun Li

    Published 2025-05-01
    “…These targets were further validated via bulk RNA-seq, single-cell RNA-seq, and spatial transcriptomics, which revealed differential expression patterns across various cell types in the HCC tumor microenvironment. …”
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  6. 1666

    A usability evaluation framework for a mobile application in supporting home-based rehabilitation for stroke patients: A qualitative study by Shih-Ying Chien

    Published 2025-05-01
    “…These outcomes from usability evaluation contribute to a deeper understanding of the usage patterns of mobile healthcare applications and help to identify areas for improvement in the current design, thereby enhancing the potential for the use of the app in home-based long-term care and rehabilitation.…”
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  7. 1667

    Genome-wide identification of PP2A gene family in Camellia sinensis reveals the potential role of CsPP2A-TON2/FASS1 in abiotic stress by Surjit Bhattacharjee, Abhirup Paul, Aradhana Jana, G. Meher Unnati, Deepak R., Ye Miao, Honglin Lu, Guoxin Shen, Neelam Mishra

    Published 2025-05-01
    “…Analysis of cis-elements, gene ontology, and expression patterns of CsPP2A genes under various stresses, combined with prior research on the PP2A gene family in other plants, suggests that the PP2A family plays a role in regulating phytohormone (auxin, salicylic acid, gibberellin, abscisic acid, MeJA) responses during stress in C. sinensis. …”
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  8. 1668

    Study on Enzyme Activity and Metabolomics during Culture of Liquid Spawn of <i>Floccularia luteovirens</i> by Yanqing Ni, Qiuhong Liao, Siyuan Gou, Tongjia Shi, Wensheng Li, Rencai Feng, Zhiqiang Zhao, Xu Zhao

    Published 2024-08-01
    “…By comparing three different culture stages (10 days, 20 days, and 30 days), 299, 291, and 381 metabolites, respectively, showed different accumulation patterns in the comparison groups of 10d vs. 20d, 20d vs. 30d, and 10d vs. 30d. …”
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  9. 1669

    Age modulates, religious coping mediates: the role of attitude to self in cancer patients’ quality of life by Maria-Chidi C. Onyedibe, Runcie C.W. Chidebe, Runcie C.W. Chidebe, Runcie C.W. Chidebe, Barbara L. Andersen, Uzoamaka F. Ugwoke, Lawrence Ejike Ugwu, Lawrence Ejike Ugwu

    Published 2025-02-01
    “…Mediation and moderation analyses were conducted using SPSS (Version 29) and SmartPLS (Version 4).ResultsNegative generalization (β = −0.25, p &lt; 0.001) and self-criticism (β = −0.19, p &lt; 0.001) reduced physical well-being, while high standards positively influenced emotional well-being (β = 0.27, p &lt; 0.001) but negatively impacted functional well-being (β = −0.13, p &lt; 0.01). …”
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  10. 1670

    Unraveling the laser decal transfer-based printing of ZnO ceramic towards FEP-ZnO-based Piezo-Tribo hybrid nanogenerators by Arpit Kumar Singh, Anshu Sahu, Palani Iyamperumal Anand

    Published 2025-03-01
    “…The selectively transferred nanoparticles in various patterns are further grown using a hydrothermal technique. …”
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  11. 1671
  12. 1672

    Genome-wide and transcriptome analysis of PdWRKY transcription factors in date palm (Phoenix dactylifera) revealing insights into heat and drought stress tolerance by Ibrahim Khan, Lubna, Saqib Bilal, Ashraf M. M. Abdelbacki, Sang-Mo Kang, Ahmed AL-Harrasi, Sajjad Asaf, In-Jung Lee

    Published 2025-07-01
    “…Looking at the extensive importance of WRKY transcription factors (TFs) in plant growth, development and defense responses to various biotic and abiotic stresses, we conducted a study to identify and functionally annotate the WRKY TFs of P. dactylifera, with a particular focus on their involvement in drought and heat stress. …”
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  13. 1673
  14. 1674

    Toll-like receptor 3 activation enhances antitumor immune response in lung adenocarcinoma through NF-κB signaling pathway by Ang Li, Ang Li, Ang Li, Man Luo, Xiyao Liu, Hongjiao Wu, Hongjiao Wu, Hongjiao Wu, Xiaoguang Liu, Zhi Zhang, Xuemei Zhang, Xuemei Zhang, Xuemei Zhang

    Published 2025-05-01
    “…BackgroundToll-like receptor 3 (TLR3) is a pattern recognition receptor known to play a crucial role in the immune response to cancer. …”
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  15. 1675
  16. 1676
  17. 1677

    Genome-wide identification of fasciclin-like arabinogalactan proteins (FLAs) in melon and the role of CmFLA8 in glucose accumulation in fruit by Suying Wen, Ruijie Huang, Muyao Gao, Jiayin Li, Yixuan Zhou, Rundi Sun, Zhilong Bie, Jintao Cheng

    Published 2025-01-01
    “…The RNA-seq and qRT-PCR assays showed that CmFLA10 exhibited specific expression patterns in male flowers, while CmFLA12 was highly expressed in the root tissue. …”
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  18. 1678

    Molecular cloning of TPM3 gene in qinchuan cattle and its effect on myoblast proliferation and differentiation by Juntao Guo, Jianfang Wang, Ke Zhang, Zhimei Yang, Bingzhi Li, Yueting Pan, Hengwei Yu, Shengchen Yu, Sayed Haidar Abbas Raza, Belete Kuraz Abebea, Linsen Zan

    Published 2024-12-01
    “…Notably, a noticeable increase in TPM3 expression was observed in the longissimus dorsi muscle and myocardium of calves and adult cattle. Expression patterns varied during different stages of myoblast differentiation. …”
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  19. 1679

    Proteomic Analysis of Retinas in a Rat Model of High-Fat Diet-Induced Type 2 Diabetes: Implications of Interventional Targets for Nonproliferative Diabetic Retinopathy by Pang X, Bai S, Feng Z, Zhang Y, Hu B, Zhang Y

    Published 2025-04-01
    “…The expression patterns of selected differentially expressed proteins (DEPs) were validated in rat retinas via Western blotting and in aqueous humor from NPDR patients via slot blotting.Results: After the 12-w HFD and STZ injection, the rats presented typical symptoms of T2DM. …”
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  20. 1680

    Identification and evaluation of metabolic mRNAs and key miRNAs in colorectal cancer liver metastasis by Guanxuan Chen, Shiwen Wang, Meng Zhang, Wenna Shi, Ruoyu Wang, Wanqi Zhu

    Published 2025-07-01
    “…We screened the featured genes using a machine-learning technique, followed by an evaluation of their diagnostic potential for CRC liver metastasis. Additionally, we conducted a functional enrichment analysis and constructed a network of miRNA-targeted mRNAs. …”
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