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1661
Immune intrinsic escape signature stratifies prognosis, characterizes the tumor immune microenvironment, and identifies tumorigenic PPP1R8 in glioblastoma multiforme patients
Published 2025-08-01“…TIME analysis was carried out using multiple deconvolution algorithms. Additionally, functional assays including CCK8, cell cycle, and apoptosis assays were conducted on PPP1R8-silenced U251 cells using CRISPR/Cas9 technologyResultsThirty-six IERGs were associated with GBM outcomes, with 20 linked to poor survival and 16 to better outcomes. …”
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1662
Retinol and Hydroxyasiaticoside Synergistically Relieve Histamine-Induced Atopic Dermatitis Activity by Repressing TRPV1, L1R1, and CD130 Targets
Published 2024-11-01“…Quantitative RNA-seq analysis revealed that the gene expression patterns were similar in different concentration groups. …”
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1663
ENHANCEMENT OF SENSOR PANEL TACTILE TOUCH INTERFACE
Published 2025-03-01“…The neural network is designed to learn the patterns and characteristics of the signals, allowing it to accurately classify new, unseen signals. …”
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1664
Exploring potential methylation markers for ovarian cancer from cervical scraping samples
Published 2025-05-01“…Furthermore, an over-representation analysis was conducted to explore the functions associated with genes mapped from differentially methylated positions (DMPs) in comparisons between normal and tumor samples, as well as between benign and malignant samples. …”
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1665
Decoding per- and polyfluoroalkyl substances (PFAS) in hepatocellular carcinoma: a multi-omics and computational toxicology approach
Published 2025-05-01“…These targets were further validated via bulk RNA-seq, single-cell RNA-seq, and spatial transcriptomics, which revealed differential expression patterns across various cell types in the HCC tumor microenvironment. …”
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1666
A usability evaluation framework for a mobile application in supporting home-based rehabilitation for stroke patients: A qualitative study
Published 2025-05-01“…These outcomes from usability evaluation contribute to a deeper understanding of the usage patterns of mobile healthcare applications and help to identify areas for improvement in the current design, thereby enhancing the potential for the use of the app in home-based long-term care and rehabilitation.…”
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1667
Genome-wide identification of PP2A gene family in Camellia sinensis reveals the potential role of CsPP2A-TON2/FASS1 in abiotic stress
Published 2025-05-01“…Analysis of cis-elements, gene ontology, and expression patterns of CsPP2A genes under various stresses, combined with prior research on the PP2A gene family in other plants, suggests that the PP2A family plays a role in regulating phytohormone (auxin, salicylic acid, gibberellin, abscisic acid, MeJA) responses during stress in C. sinensis. …”
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1668
Study on Enzyme Activity and Metabolomics during Culture of Liquid Spawn of <i>Floccularia luteovirens</i>
Published 2024-08-01“…By comparing three different culture stages (10 days, 20 days, and 30 days), 299, 291, and 381 metabolites, respectively, showed different accumulation patterns in the comparison groups of 10d vs. 20d, 20d vs. 30d, and 10d vs. 30d. …”
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1669
Age modulates, religious coping mediates: the role of attitude to self in cancer patients’ quality of life
Published 2025-02-01“…Mediation and moderation analyses were conducted using SPSS (Version 29) and SmartPLS (Version 4).ResultsNegative generalization (β = −0.25, p < 0.001) and self-criticism (β = −0.19, p < 0.001) reduced physical well-being, while high standards positively influenced emotional well-being (β = 0.27, p < 0.001) but negatively impacted functional well-being (β = −0.13, p < 0.01). …”
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1670
Unraveling the laser decal transfer-based printing of ZnO ceramic towards FEP-ZnO-based Piezo-Tribo hybrid nanogenerators
Published 2025-03-01“…The selectively transferred nanoparticles in various patterns are further grown using a hydrothermal technique. …”
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1671
Exploration of RNA-binding proteins identified RPS27 as a potential regulator associated with Kaposi’s sarcoma development
Published 2025-02-01“…Cellular experiments were conducted for dysregulated RPS27 to explore its functions. …”
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1672
Genome-wide and transcriptome analysis of PdWRKY transcription factors in date palm (Phoenix dactylifera) revealing insights into heat and drought stress tolerance
Published 2025-07-01“…Looking at the extensive importance of WRKY transcription factors (TFs) in plant growth, development and defense responses to various biotic and abiotic stresses, we conducted a study to identify and functionally annotate the WRKY TFs of P. dactylifera, with a particular focus on their involvement in drought and heat stress. …”
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1673
Recursive Class Connectivity Classification (R3C) Applied to Binary Image Segmentation for Improved Infant Fingerprint Enhancement
Published 2025-01-01“…A qualitative analysis further demonstrates that R3C reconnects fragmented ridge patterns, improving the visual quality of segmentation. …”
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1674
Toll-like receptor 3 activation enhances antitumor immune response in lung adenocarcinoma through NF-κB signaling pathway
Published 2025-05-01“…BackgroundToll-like receptor 3 (TLR3) is a pattern recognition receptor known to play a crucial role in the immune response to cancer. …”
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1675
Anticancer activity of RM-3-22: a TAZQ-based hydroxamic acid derivative targeting NSCLC in vitro and in vivo
Published 2025-06-01“…Different in silico studies were also conducted to check the clinical relevance and expression pattern of the RM-3-22-induced gene. …”
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1676
FACTORS ASSOCIATED WITH ANXIETY AND DEPRESSION SPECTRUM DISORDERS IN BEHCHET’S DISEASE
Published 2018-07-01“…Sleep disorders, asthenic syndrome, and CI are significant in the pattern of ADSDs.…”
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1677
Genome-wide identification of fasciclin-like arabinogalactan proteins (FLAs) in melon and the role of CmFLA8 in glucose accumulation in fruit
Published 2025-01-01“…The RNA-seq and qRT-PCR assays showed that CmFLA10 exhibited specific expression patterns in male flowers, while CmFLA12 was highly expressed in the root tissue. …”
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1678
Molecular cloning of TPM3 gene in qinchuan cattle and its effect on myoblast proliferation and differentiation
Published 2024-12-01“…Notably, a noticeable increase in TPM3 expression was observed in the longissimus dorsi muscle and myocardium of calves and adult cattle. Expression patterns varied during different stages of myoblast differentiation. …”
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1679
Proteomic Analysis of Retinas in a Rat Model of High-Fat Diet-Induced Type 2 Diabetes: Implications of Interventional Targets for Nonproliferative Diabetic Retinopathy
Published 2025-04-01“…The expression patterns of selected differentially expressed proteins (DEPs) were validated in rat retinas via Western blotting and in aqueous humor from NPDR patients via slot blotting.Results: After the 12-w HFD and STZ injection, the rats presented typical symptoms of T2DM. …”
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1680
Identification and evaluation of metabolic mRNAs and key miRNAs in colorectal cancer liver metastasis
Published 2025-07-01“…We screened the featured genes using a machine-learning technique, followed by an evaluation of their diagnostic potential for CRC liver metastasis. Additionally, we conducted a functional enrichment analysis and constructed a network of miRNA-targeted mRNAs. …”
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