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1621
Trends and key contributors in peripheral nerve regeneration research: A bibliometric study
Published 2025-06-01“…A bibliometric analysis was conducted to provide a structured overview of research trends, intellectual impact, and evolving themes in peripheral nerve regeneration. …”
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1622
Quantitative study on contribution of dynamic imbibition to oil production during fracturing and huff-n-puff in tight reservoirs
Published 2025-03-01“…Furthermore, the contribution of imbibition and displacement on oil recovery during the dynamic imbibition process showed opposite patterns. The main research conclusions are as follows. …”
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1623
Unraveling the molecular mechanisms of paclitaxel in high-grade serous ovarian cancer through network pharmacology
Published 2025-05-01“…Functional enrichment analysis was conducted using Gene Ontology and the Kyoto Encyclopedia of Genes and Genomes. …”
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1624
RNF213 governs divergent tumor-immune dynamics across human cancers: a prognostic biomarker for immunotherapy stratification
Published 2025-07-01“…Methods Leveraging data from The Cancer Genome Atlas (TCGA) and additional publicly available datasets, we performed a systematic analysis of RNF213 expression patterns, mutation frequencies, and their relationships with clinical outcomes. …”
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1625
Occupational Exposure to Engine Exhausts and Prostate Cancer Risk
Published 2025-07-01“…Results were independent from prostate cancer screening patterns.…”
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1626
Disentangled similarity graph attention heterogeneous biological memory network for predicting disease-associated miRNAs
Published 2024-12-01“…Additionally, various ablation studies were conducted to validate the contributions of different modules within the framework, and’s encoding statuses and memory units of DiGAMN were visualized to explore the utility and functionality of its modules. …”
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1627
Promoting Resilience in Youth through Mindfulness mEditation (PRYME): Study protocol for a randomized controlled trial investigating the effects of mindfulness training as add-on t...
Published 2025-02-01“…Secondary outcomes include measures of self-compassion, rumination, experiential avoidance, and well-being. In addition, (functional) magnetic resonance imaging and computerized cognitive tasks are conducted at baseline and at end of treatment. …”
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1628
Nitrogen addition promotes the coupling of deep soil carbon and nitrogen under different vegetation restoration types in the Chinese Loess Plateau
Published 2025-03-01“…Afforestation should be conducted in a way of natural restoration. This study provides novel insights into the regulatory mechanisms of C and N biogeochemistry and the afforestation patterns of vegetation restoration in arid and semi-arid regions.…”
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1629
Transcriptomics-Based Study of Immune Genes Associated with Subclinical Mastitis in Bactrian Camels
Published 2025-02-01“…Overall, 1722 differentially expressed genes were sequenced in the blood samples of CMT-positive and CMT-negative Bactrian camels, including 1061 upregulated and 661 downregulated genes. After conducting gene ontology functional enrichment, 453 differentially expressed genes were identified. …”
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1630
ELECTROMYOGRAPHY INDICATORS IN DIFFERENT PERIODS OF USING OF THE REMOVABLE DENTURES IN PATIENTS WITH ACRYLATE INTOLERANCE
Published 2020-03-01“…On the 15th day of observation, the electromyographic pattern in patients of group 3 changed and was characterized by a pronounced tendency to normalized indicators of the activity and rest time. …”
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1631
Mortality rates in a cohort of infants attending immunization clinics in Uganda (2017-2019).
Published 2025-01-01“…The outcome of interest was child mortality, and the independent variables were mother's age; infant HIV exposure status; infant sex; family socioeconomic status; marital status; education level; malaria during pregnancy; birth attendee; mother's ART initiation; mode of transport to health facilities; breastfeeding pattern; 4 or more ANC visits; and mother's baseline viral load nonsuppression and place of delivery. …”
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1632
Multi-omics analysis reveals the role of the autophagy-related gene AGT in chemotherapy resistance in colorectal cancer and the therapeutic potential of its inhibitors
Published 2024-11-01“…Through multi-omics analysis, this study explores the expression patterns, functions, and potential role of the autophagy-related gene Angiotensinogen (AGT) in colorectal cancer (CRC), particularly in relation to chemotherapy resistance. …”
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1633
Topologically Optimized Anthropomorphic Prosthetic Limb: Finite Element Analysis and Mechanical Evaluation Using Plantogram-Derived Foot Pressure Data
Published 2025-04-01“…This innovative approach allows the development of tailored prosthetic limbs with optimal replication of the human motion patterns, resulting in improved patient outcomes and higher success rates. …”
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1634
Cross-Tissue Regulatory Network Analyses Reveal Novel Susceptibility Genes and Potential Mechanisms for Endometriosis
Published 2024-10-01“…To further delve into mechanisms, two-sample network MR analyses were conducted. At last, bioinformatics analyses were employed to enhance our understanding of the functional implications and expression patterns of these identified genes. …”
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1635
Differential regulation of calcium-NFAT signaling pathway by Akt isoforms: unraveling effector dynamics and exhaustion of cytotoxic T lymphocytes in tumor microenvironment
Published 2025-03-01“…Given the unique expression patterns and functions of the three Akt isoforms in immune cells, we proposed that Akt isoforms in CTLs may regulate effector functions and T-cell exhaustion distinctly.Methods In this study, we genetically modified tumor/virus-antigen-specific T-cell receptor tg CTLs to ectopically express Akt isoforms via retroviral transduction. …”
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1636
eQTL and multi-omics integration reveal PPIH as a prognostic and immunotherapeutic biomarker
Published 2025-08-01“…A comprehensive series of multi-omics bioinformatics analyses was subsequently conducted to assess the gene’s expression patterns, genomic alterations, prognostic relevance, and associations with the tumor microenvironment (TME) across various cancer types. …”
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1637
Multiomic analysis of the synthetic pathways of secondary metabolites in tobacco leaves at different developmental stages
Published 2025-06-01“…Despite substantial progress, the comprehensive regulatory landscape governing secondary metabolite biosynthesis during N. tabacum leaf development remains largely unclear.MethodsTo better understand the molecular regulatory mechanisms underlying the biosynthesis of secondary metabolites, particularly flavonoids, during N. tabacum leaf development, we conducted a transcriptomic and non-targeted metabolomic sequencing and analysis at three critical developmental stages: vigorous growth stage (T1), topping stage (T2), and harvest stage (T3).ResultsBased on our transcriptomic and metabolomic data, 25 unigenes exhibiting stage-specific expression patterns that were strongly associated with flavonoid accumulation were identified. …”
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1638
Genetic Alterations in War-Related Post-Traumatic Stress Disorder: A Systematic Review
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1639
Dietary supplementation with L-carnitine elevates intracellular carnitine levels and affects gene expression of SLC25A20 and COX4I1, as well as non-mitochondrial respiration of bov...
Published 2025-07-01“…The gene expression of carnitine-acylcarnitine translocase (SLC25A20) in PBMC remained stable in CAR, whereas it was upregulated in CON during the LPS challenge, suggesting an adaptation to increased energy demands in CON. A contrasting pattern was detected for the gene expression of cytochrome c oxidase subunit 4I1 (COX4I1), with stable levels in CON and a downregulation in CAR due to LPS injection. …”
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1640
The Trehalose-6-Phosphate Synthase and Trehalose-6-Phosphate Phosphatase in Cocoa (Theobroma cacao L.): Genome-Wide Identification and Expression Analysis
Published 2025-03-01“…Based on publicly available datasets, expression profiling demonstrated differential expression patterns of TcTPP and TcTPS genes during embryo development and under biotic stress conditions, such as pathogen infection by Phytophthora megakarya. …”
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