Construction and validation of acetylation-related gene signatures for immune landscape analysis and prognostication risk prediction in luminal breast cancer by Mengdi Zhu, Jinna Lin, Haohan Liu, Jingru Wang, Nianqiu Liu, Yudong Li, Hongna Lai, Qianfeng Shi

“…Mouse model was constructed for in vivo validation of KAT2B and TAF1L function. Results In our study, we utilized the TCGA-BRCA database to conduct a comprehensive analysis of the acetylation regulatory pattern in luminal breast cancer. …”
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Genetic Parameters, Linear Associations, and Genome-Wide Association Study for Endotoxin-Induced Cortisol Response in <i>Holstein heifers</i> by Bruno A. Galindo, Umesh K. Shandilya, Ankita Sharma, Flavio S. Schenkel, Angela Canovas, Bonnie A. Mallard, Niel A. Karrow

“…Lipopolysaccharide (LPS) endotoxin is a well-characterized microbe-associated molecular pattern (MAMP) that forms the outer membrane of both pathogenic and commensal Gram-negative bacteria. …”
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Altered microstate C and D dynamics in high social anxiety: a resting-state EEG study by Huoyin Zhang, Huoyin Zhang, Binyu Peng, Yutong Liu, Yu Xi, Yi Lei, Yi Lei

“…While its neural processing patterns are well-documented, the millisecond-level temporal dynamics of brain functional networks remain poorly understood. …”
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Filling knowledge gaps: A methodological approach for the rapid investigation of species with restricted populations by André Cesar Furlaneto Sampaio, Pablo Melo Hoffmann, Elivelton Marcos Gurski, Ollyver Rech Bizarro, Santiago José Elías Velazco, Marcos Bergmann Carlucci, Marília Borgo, Mayara Monteiro Ferreira, Alessandro Camargo Angelo, Christopher Thomas Blum

“…In the third phase, we analyzed spatial patterns using Morisita’s Index and Ripley’s K function. …”
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Automatic detection of lucky bamboo nodes based on Improved YOLOv7 by Jing Zhang, Jing Zhang, Jing Zhang, Ruoling Deng, Ruoling Deng, Ruoling Deng, Chengzhi Cai, Erpeng Zou, Haitao Liu, Haitao Liu, Mingxin Hou, Xinzhi Chen, Huamin Lin, Zhenye Wei

“…Future work will address limitations in detecting nodes obscured by mottled patterns or severe occlusions by expanding label categories during training.…”
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Inflammation and platelet hyperresponsiveness in coronary artery disease and the influence of Talin-1/αIIbβ3-mediated bidirectional signaling pathway by Shengnan Shi, Jiaming Gao, Yehao Zhang, Min Zhan, Zhanfei Tan, Peili Wang, Jianhua Fu, Jianxun Liu

“…Inflammation markers, platelet aggregation function, and CD62p levels were assessed using flow cytometry. …”
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Distribution, behavior and diet of the Asiatic black bear in human modified landscapes by Hadi Fahimi, Mahmood Soofi, Nahid Ahmadi, Ali T. Qashqaei, Hamidreza Heidari, Haaken Bungum, Bent Rech, Jonas Trepel, Matthias Waltert

“…The broad negative effects of land-use conversion for agriculture on wildlife species are well known, but few studies have evaluated how different land-use types impact spatiotemporal patterns and trophic strategy of large carnivores. …”
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To operate or not to operate? The impact of surgical treatment on quality of life in women with ovarian endometriosis by Emanuela Spagnolo, Emanuela Spagnolo, David Ramiro-Cortijo, David Ramiro-Cortijo, Blanca Díaz Fuentes, María Suarez Vega, Lucía Calvillo-Fernández, Ana López, Ana López, Alicia Hernández, Alicia Hernández

“…OE- S exhibited intermediate health and quality of life patterns between control and DE groups, whereas OE- NS was more similar to DE.ConclusionPsychological well-being and social support are reduced in all endometriosis groups, but surgical treatment in women with ovarian endometriosis preserve vitality, sexual, and occupational functions. …”
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Unveiling the role of coagulation-related genes in acute myeloid leukemia prognosis and immune microenvironment through machine learning by Liyun Ji, Yanxia Yang, Siyue Ma

“…We further identified differentially expressed genes (DEGs) between groups and conducted functional enrichment analyses. Additionally, a prognostic model was constructed using machine learning techniques, and its prognostic ability was validated. …”
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Does wetland degradation impact bird diversity differently across seasons? A case study of Zoige Alpine Wetland ecosystem by Chen Yang, Siheng Chen, Tianpei Guan

“…Our study recorded a total of 106 bird species from 32 families and 14 orders, revealing distinct seasonal patterns in bird community composition and diversity. …”
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Vestibular afferent neurons develop normally in the absence of quantal/glutamatergic input by Katherine Regalado Núñez, Katherine Regalado Núñez, Daniel Bronson, Daniel Bronson, Ryan Chang, Radha Kalluri, Radha Kalluri, Radha Kalluri

“…Patch-clamp recordings showed that biophysical diversity of vestibular ganglion neurons in the Vglut3-ko mice is comparable to that found in wild-type controls, with a similar range firing patterns at both immature and juvenile ages. However, our results suggest a subtle biophysical alteration to the largest ganglion cells (putative somata of central zone afferents); those in the knockout had smaller net conductance and were more excitable than those in the wild type.DiscussionThus, unlike in the auditory nerve, glutamatergic signaling is unnecessary for producing biophysical diversity in vestibular ganglion neurons. …”
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Alteration in motor control in patients with low back pain and myotonic syndrome of lumbar osteochondrosis by V.A. Kolesnichenko, H.H. Holka, I.V. Hresko, V.V. Burlaka, V.V. Vesnin, B.P. Vvedensky, D.B. Vvedensky

“…The majority of studies associate low back pain with limitation of motor function of the spine and muscle control of the lumbar-pelvic area, however, in a number of reports such a connection was not found. …”
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Targeting Cancer with Paris’ Arrow: An Updated Perspective on Targeting Wnt Receptor Frizzled 7 by Kieran Hodson, Hector M. Arredondo, William E. Humphrey, Dustin J. Flanagan, Elizabeth Vincan, Karl Willert, Helen B. Pearson, Toby J. Phesse

“…Additionally, we present new figures generated by our group using the publicly available Pan-Cancer Atlas RNAseq datasets, highlighting FZD7 expression patterns in patient samples. This integrated approach aims to provide updated insights into the function of FZD7 during cancer and its growing status as an attractive target for therapy. …”
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Assessment of the attractiveness of a region for coffee production: the case of Karo Regency by Syahbudin Hasibuan, Zulkarnain Lubis, Sri Ariani Safitri, Zahraturrahmi Zahraturrahmi, Marizha Nurcahyani

“…Polyculture planting patterns can diversify farmers’ income while improving the supply chain, creating a fairer distribution of profits, and supporting Karo as a leading coffee centre in North Sumatra.…”
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Transcriptome-wide identification and systematic analysis of the Retrotransposon genes and their roles in ginsenoside biosynthesis in Panax ginseng by Chaofan Wang, Ruicen Liu, Dinghui Wang, Li Li, Yue Jiang, Yanfang Wang, Kangyu Wang, Mingzhu Zhao, Yi Wang, Meiping Zhang

“…Results 1,301 Retrotransposon genes were identified in ginseng transcriptome using bioinformatics methods, and a systematic analysis was conducted on their gene structures, phylogenetic relationships, and expression patterns. …”
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Deep Learning–Based Chronic Obstructive Pulmonary Disease Exacerbation Prediction Using Flow-Volume and Volume-Time Curve Imaging: Retrospective Cohort Study by Eun-Tae Jeon, Heemoon Park, Jung-Kyu Lee, Eun Young Heo, Chang Hoon Lee, Deog Kyeom Kim, Dong Hyun Kim, Hyun Woo Lee

“…Acute exacerbations (AE) of COPD (AE-COPD) are key determinants of disease progression; yet, existing predictive models relying mainly on spirometric measurements, such as forced expiratory volume in 1 second, reflect only a fraction of the physiological information embedded in respiratory function tests. Recent advances in artificial intelligence (AI) have enabled more sophisticated analyses of full spirometric curves, including flow-volume loops and volume-time curves, facilitating the identification of complex patterns associated with increased exacerbation risk. …”
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Multi‐omics profiling identifies TNFRSF18 as a novel marker of exhausted CD8⁺ T cells and reveals tumour‐immune dynamics in colorectal cancer by Tengfei Jia, Yingxi Guo, Xin meng Cheng, Zeyang Zhou, Xiaojiang Xu, Hebin Liu, Xiaodong Yang

“…T cell exhaustion markers, immune clonality, gene expression profiles, and the spatial distribution of both tumour cells and immune cells were systematically profiled. Functional enrichment and intercellular communication analyses were conducted. …”
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The Cosmic Evolution and Spatial Distribution of Multiphase Gas Associated with QSOs by Zeyu Chen, Enci Wang, Hu Zou, Haoran Yu, Zhicheng He, Huiyuan Wang, Yang Gao, Cheqiu Lyu, Cheng Jia, Chengyu Ma, Weiyu Ding, Runyu Zhu, Xu Kong

“…We also find that W _FeII / W _MgII increases toward lower redshifts, which can be attributed to evolving star formation histories and/or changes in initial mass function for galaxies. By leveraging multiple absorption tracers, we conduct the first comprehensive investigation of diffuse, multiphase gas from the circumgalactic medium to cosmological scales, offering new insights into baryon cycles and the transport of metals throughout cosmic time.…”
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Pathohistological properties and histomorphometric characteristics of cancellous bone tissue in iliobiopsies of patients with osteogenesis imperfecta by V. V. Grigorovsky, A. M. Zyma

“…In OI-patients trabecular bone tissue had the complex pattern formed by basophylic cemental lines which outlined interstitial microstructures of lamellar and woven kind. …”
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STAU1 exhibits oncogenic characteristics and modulates alternative splicing and gene expression in lung adenocarcinoma cells by Ling Zhang, Zhen Peng, Wei Ding, Haixia Wu, Rong Guo, Dewei Li, Ling Niu, Xuemei Wei

“…However, its specific functions and molecular mechanisms in lung adenocarcinoma (LUAD) remain underexplored. …”
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