Aggressive Periodontitis: A case report with exome sequencing and functional characterization of identified variant by Waheed Awotoye, Patricia Ayanbadejo, Steven Eliason, Kehinde Umeizudike, Ayodele Ogundana, Dan Su, Tadkamol Krongbaramee, Emmanuel Aladenika, Azeez Alade, Abimbola Oladayo, Abdul-Warith Akinshipo, Tamara Busch, Wasiu Adeyemo, Brad Amendt, Azeez Butali

“…Sequencing analysis of the coding regions of NOD2 was conducted using individuals of African ancestry, to identify the pathogenic protein-altering variants in individuals with AgP using: 1) In Silico tools and clinical variant classification system; 2) IF staining to understand the expression pattern, and 3) In vitro cell based assay to understand the variant protein function. …”
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Drivers of Structural and Functional Resilience Following Extreme Fires in Boreal Forests of Northeast China by Jianyu Yao, Xiaoyang Kong, Lei Fang, Zhaohan Huo, Yanbo Peng, Zile Han, Shilong Ren, Jinyue Chen, Xinfeng Wang, Qiao Wang

“…The spatial asynchrony in resilience patterns between structural and functional parameters highlighted the complex interplay of climatic drivers and ecological processes during post-disturbance recovery. …”
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Detecting the antibacterial activity of green synthesized silver (Ag) nanoparticles functionalized with ampicillin (Amp) by Baghdad Science Journal

“…In the current study, synthesis and characterization of silver nanoparticles (AgNPs) before and after functionalization with ampicillin antibiotic and their application as anti-pathogenic agents towards bacteria were investigated. …”
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FUNCTIONING OF THE CAR PARKING PLACES NEAR HOUSES: FORMULATION OF THE PROBLEM OF THE ROAD CITY NETWORK by I. E. Agureev, D. A. Yurchenko

“…Creating transport models requires knowledge of the traffic flows’ formation and functioning. The paper formulates a goal and poses tasks for the research conducting of the adjoining territories of residential areas in Tula as one of the urban traffic flows’ sources and of the identifying patterns of the parking places near houses’ influence on the road network loading.Materials and methods. …”
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Functional Connectivity Changes in Primary Motor Cortex Subregions of Patients With Obstructive Sleep Apnea by Lifeng Li, Qimeng Shi, Bowen Fang, Yuting Liu, Xiang Liu, Yongqiang Shu, Yingke Deng, Yumeng Liu, Haijun Li, Junjie Zhou, Dechang Peng

“…Future research should explore M1 FC patterns as diagnostic markers and neuromodulation therapies.…”
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Abnormal intrahemispheric and interhemispheric dynamic functional connectivity density in male alcohol use disorder by Bohui Mei, Yarui Wei, Longyao Ma, Qiuying Tao, Jinghan Dang, Jieping Sun, Mengzhe Zhang, Yong Zhang, Jingliang Cheng

“…However, brain activity is highly dynamic.MethodsTo address this, we analyzed the dynamic changes in intrahemispheric and interhemispheric connectivity patterns from 55 AUD patients and 32 healthy controls. …”
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Paradise fish (Macropodus opercularis) as a complementary translational model for emotional and cognitive function by Zoltán K. Varga, Diána Pejtsik, Tímea Csorvási, Éva Mikics, Ádám Miklósi, Máté Varga

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FUNCTIONAL AND METABOLIC FEATURES OF BLOOD PHAGOCYTES AT DIFFERENT FORMS OF TUBERCULAR INFLAMMATORY PROCESS OF LUNGS by O. V. Berdyugina, A. V. Yershova

“…We have revealed a relative decrease in lymphocyte quantities in the patients from tuberculoma which corresponded to increased granulocyte quantities of granulocytes and monocytes in the patients’ blood. The conducted study allowed us to make a conclusion that each clinical form of tuberculosis id characterized by a specific immunological pattern.In the patients with tuberculoma, we have revealed a decrease of phagocytic, functional and metabolic activities of monocytes is noted, along with increased quantities of CD11b+ and CD11c+ adhesion molecules on granulocytes, increased numbers of T-lymphocytes, and decreased amounts of NK-cells. …”
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Research on the Correlation between Balance Function and Core Muscles in Patients With Adolescent Idiopathic Scoliosis by Si-Jia Li, Qing Yue, Qian-Jin Liu, Yan-Hua Liang, Tian-Tian Zhou, Xiao-Song Li, Tian-Yang Feng, Tong Zhang

“…Conclusion These findings suggest distinct postural control patterns in AIS patients, highlighting the importance of targeted interventions to improve balance and core muscle function in this population.…”
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Evaluation of the renal function among sickle cell patients: a cross-sectional study by Talal Qadah, Anwar Refaei

“… This cross-sectional study aimed to explore the implications and effects of hematological and kidney function patterns in individuals with sickle cell disorder (SCD) residing in the Jazan Region of Saudi Arabia. …”
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Clinical phenotype and functional influence of GRIN2A variants in epilepsy‐aphasia syndrome by Lu Zhang, Yiran Duan, Rui Ma, Jiaqi Han, Na Pan, Lehong Gao, Yuping Wang

“…A summary of previously published GRIN2A missense variants was conducted to investigate the genotypic‐phenotypic‐functional correlations. …”
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Altered inter-hemispheric and intra-hemispheric functional connectivity dynamics in male cigarette smokers by Mengzhe Zhang, Huiyu Huang, Xiaoyu Niu, Jinghan Dang, Jieping Sun, Qiuying Tao, Weijian Wang, Shaoqiang Han, Jingliang Cheng, Yong Zhang

“…The functional connections of whole-brain were decomposed into inter-hemispheric and intra-hemispheric connections. …”
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Mapping Genetic Associations With Functional Brain Area Alterations in Schizophrenia and Implications for Cortical Development by Jun‐Ding Zhu, Chih‐Yun Chung, Shu‐Fei Lin, Shih‐Jen Tsai, Albert C. Yang, Pei‐Shan Hou

“…T1‐weighted MRI scans were processed to assess GM volume changes, and the cerebral cortex was parcellated into BAs for detailed analysis. GWAS was conducted to identify schizophrenia‐associated genetic variants, followed by functional mapping, single‐cell RNA sequencing analysis of developing human cortical cells, and in situ hybridization analysis in the developing mouse neocortex. …”
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The effect of ambient temperature on thyroid function parameters: a daily level panel study by Tao Wang, Hailin Ma, Zhaoqing Jin, Ting Yang, Zhiqiang Zhao, Aerdake Wulalibieke, Qishan Wang, Yu Cao, Shenghong Yang

“…Objective We sought to examine non-linear and lagged patterns in how extremely low ambient temperature is associated with thyroid function parameters. …”
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The contrasted impacts of grasshoppers on soil microbial activities in function of primary production and herbivore diet by Ibanez, Sébastien, Foulquier, Arnaud, Brun, Charles, Colace, Marie-Pascale, Piton, Gabin, Bernard, Lionel, Gallet, Christiane, Clément, Jean-Christophe

“…This highlights the multidimensional feature of the impacts of herbivory on ecosystem functioning, both in space and time. …”
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Bridging the gap: enhancing blood regulatory functions in African contexts through comparative analysis by Washington T. Samukange, Washington T. Samukange, Washington T. Samukange, Verena Kluempers, Chancelar Kafere, Kristina Heinrich, Joanna Atemnkeng, Alireza Khadem Broojerdi, Florence Tirane, Edwin Nkansah, Shani Maboko, Linda Nhukarume, Khamusi Mutoti, Noel Aineplan, Helga Gardasdottir, Helga Gardasdottir, Helga Gardasdottir, Aukje K. Mantel-Teeuwisse, Jens Reinhardt

“…The comparison of group averages for the ML3-designated NRAs against the non-designated NRAs revealed a higher score 91% (range: 71%−100%) for ML3-designated NRAs as opposed to a lower score of 71% (range: 49%−100%) for the non-designated NRAs for the registration and marketing authorization function. This pattern, however, was not observed for the comparison of group averages for the approval of blood, blood components, and plasma for fractionation or processes function where the ML3-designated NRAs scored 47% (range 19%−72%) against 46% (range 23%−88%) for the non-ML3-designated NRAs.ConclusionMost of the NRAs excelled in implementing sub-indicators for the registration and marketing authorization (of plasma-derived medicines) function. …”
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Early functional changes in lewy body dementia: roles of dynamics, locus coeruleus, and compensation by Kristína Mitterová, Eva Výtvarová, Anežka Kovářová, Martin Lamoš, Jan Fousek, Irena Rektorová

“…Abstract Dementia with Lewy bodies (DLB) is marked by multidomain cognitive impairments, with fluctuations in cognition and alertness being among the most common clinical features. Disruptions in functional connectivity are thought to underlie these fluctuations, but it remains unclear whether such patterns are already present at prodromal stages. …”
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Global research trajectories in gut microbiota and functional constipation: a bibliometric and visualization study by Shun Seng Ong, Lianjie Xu, Ching Wei Ang, Xiaoyue Deng, Hai Lu, Hai Lu, Tianshu Xu, Tianshu Xu

“…BackgroundFunctional constipation (FC) negatively impacts quality of life and is associated with gut microbiota (GM) imbalances. …”
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Dietary supplement use in high-intensity functional training (HIFT) athletes by competition level by Jack Livingston, Sofea Smith, Kworweinski Lafontant, Claudia Gonzalez, Michelle Da Silva Barbera, Linh Nguyen, Susan Kampiyil, Jeffrey R. Stout, David H. Fukuda

“…While a multitude of DS may be beneficial for HIFT athletes, yet usage patterns unclear.Methods Forty-nine HIFT athletes (24 women, 25 men; Age = 37.8 ± 10.5 years; BMI = 25.7 ± 3.7 kg/m2) completed a supervised Qualtrics cross-sectional survey. …”
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Functional connectivity in distributed cortical networks associated with semantic processing in healthy older adults by Kailey G. Langer, Kailey G. Langer, Alexandria G. O’Neal, Alexandria G. O’Neal, Amanda Garcia, Alexa Chen, Eric C. Porges, Eric C. Porges, John B. Williamson, John B. Williamson, John B. Williamson, Adam J. Woods, Adam J. Woods, Ronald A. Cohen, Ronald A. Cohen

“…Building upon our previous findings that delineate task-relevant semantic network activation, this study investigates connectivity patterns in additional higher-order cortical networks during a semantic association task in cognitively healthy older adults.MethodsA total of 33 older adults (61% women, 94% White, aged 70.03 ± 11.28, 16.36 ± 2.62 years of education) completed task-based functional MRI involving semantic (abstract and concrete) and phonemic (rhyming) decisions. …”
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