THE RAILWAY TO THE PACIFIC OCEAN (FOR THE 100-TH ANNIVERSARY OF THE TRANS-SIBERIAN RAILWAY) by V. Persianov, A. Kurbatova, E. Kurbatova

“…It covers the situation on Russia’s railways in the second half of the 19th century and debatable questions related to the selection of railway alignment, its function and financing of construction. …”
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Unveiling migraine subtype heterogeneity and risk loci: integrated genome-wide association study and single-cell transcriptomics discovery by Shuxu Wei, Yan Quan, Xinyi Li, Suiqin Zhong, Ling Xiao, Chao Yang, Ronghuai Shen, Xiaojia Lu, Lingbin He, Youti Zhang, Xianxi Huang

“…But they showed divergent functional architectures in functional genomic annotations, with MA enriched in conserved regulatory elements (e.g., Backgrd_Selection_StatL2_0, enrichment = 1.38, P = 5.47 × 10−6) and MO in vascular pathways (e.g., GERP.NSL2_0, enrichment = 2.12, P = 1.04 × 10−6). …”
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Case Report: Managing Odontoma and Molar-Incisor-Hypomineralization Challenges in Orthodontics [version 3; peer review: 2 approved] by Sohaib Shujaat, Faisal O. Alsharif, Maram A. Alqahtani, May Aleraij, Khalid Albawardi, Nora Alhazmi

“…Subsequently, orthodontic treatment was initiated to correct occlusion and alignment. After successful space management and canine eruption, restorative procedures were carried out to improve the esthetics and function of MIH-affected teeth. …”
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Resistance training as a modulator of inflammation and cognition by Jacqueline Goodrich, Jamie L. Tartar, Jonathan Banks, Francesca Leon, Jose Antonio

“…Research has shown that elevated levels of inflammatory biomarkers such as interleukin-6, C-reactive protein, and cortisol can impair cognitive function, highlighting the need for preventive measures. …”
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'Hypo box' audit to assess its presence, contents compliance and location on the medical wards in accordance to the Joint British Diabetes Societies for Inpatient Care guidelines by Ayley Loh, Elizabeth Humberstone, Jeyasurya Subbarayan, Doom Joy Chen-Unongo, Jeyanthy Rajkanna

“…Staff knowledge of the ‘hypo box’ function, contents and location was lacking. While most staff conducted daily checks, there was still non-compliance. …”
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Evidence supporting a catalytic pentad mechanism for the proteasome and other N-terminal nucleophile enzymes by Darlene Fung, Aida Razi, Michael Pandos, Benjamin Velez, Erignacio Fermin Perez, Lea Adams, Shaun Rawson, Richard M. Walsh, John Hanna

“…Finally, we show that two patient-derived proteasome mutations compromise function of the serine/aspartate unit in yeast, suggesting that defective pentad function may underlie some human proteasomopathies.…”
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Identifying insertion mutations by whole-genome sequencing by Harold E. Smith

“…Insertion mutagenesis via mobile genetic element is a common technique for the analysis of gene function in model organisms. Next-generation sequencing offers an attractive approach for localizing the site of insertion, but alignment-based mapping of mobile genetic elements is challenging. …”
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A Review of Constraint-Handling Techniques for Evolution Strategies by Oliver Kramer

“…Covariance matrix adaptation evolution strategies offer a solution to this alignment problem. Last, metamodeling of the constraint boundary leads to significant savings of constraint function calls and to a speedup by repairing infeasible solutions. …”
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Modeling New Nature of Extraction and State Identification of Vibration Shock Signals From Hydroelectric Generating Units Using LCGSA Optimized RBF Combined With CEEMDAN Sample Ent... by Xiang Li, Yun Zeng, Jing Qian, Boyi Xiao, Neng Fei, Fang Dao, Yidong Zou

“…This paper introduces a novel fault diagnosis approach that leverages a wavelet threshold algorithm for initial signal preprocessing and enhances the Radial Basis Function (RBF) neural network with an optimized Gravitational Search Algorithm (GSA). …”
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Pulse Dispersion in Phased Arrays by Randy L. Haupt, Payam Nayeri

“…Phased array antennas cause pulse dispersion when receiving or transmitting wideband signals, because phase shifting the signals does not align the pulse envelopes from the elements. This paper presents two forms of pulse dispersion that occur in a phased array antenna. …”
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Intentions in reconstructive plastic surgery among post-bariatric patients in Brazil’s public health service by Priscila Chiarello de Souza Pinto Abdalla, Juan Carlos Montano Pedroso, Rafael Cauê Katayama, Sarhan Sydney Saad, Gabriel de Almeida Arruda Felix, Marília Baeninger, Alfredo Gragnani

“…Targeted counseling may help align expectations and enhance post-bariatric care for patients.…”
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Interactive effects of temperature, cadmium, and hypoxia on rainbow trout (Oncorhynchus mykiss) liver mitochondrial bioenergetics by John O. Onukwufor, Collins Kamunde

“…Fish in their natural environments possess elaborate mechanisms that regulate physiological function to mitigate the adverse effects of multiple environmental stressors such as temperature, metals, and hypoxia. …”
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Understanding the Role of Organic Hole Transport Layers on Pinhole Blocking and Performance Improvement in Sb2Se3 Solar Cells by Thomas P. Shalvey, Christopher H. Don, Leon Bowen, Tim D. Veal, Jonathan D. Major

“…A Schottky barrier at the Au‐Sb2Se3 contact despite the deep work function of gold implies Fermi level pinning due to a defective interface, which each of the organic HTMs are equally capable of alleviating.…”
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Characterization of the deleted in autism 1 protein family: implications for studying cognitive disorders. by Azhari Aziz, Sean P Harrop, Naomi E Bishop

“…Evidence for remarkable DIA1L gene expansion was found in B. floridae. Amino acid alignments of DIA1 family gene products revealed a potential Golgi-retention motif and a number of conserved motifs with unknown function. …”
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A Study of Hypothyroidism in Chronic Kidney Disease (CKD) Patients by Sudharsanan V, Prabhu Shankar S, Viknesh V

“…Correlation analysis revealed a negative association between estimated glomerular filtration rate (eGFR) and TSH (r = -0.147, p = 0.023), suggesting declining kidney function aligns with thyroid dysfunction. Conclusion: This study highlights a notable correlation between CKD progression and the occurrence of hypothyroidism, particularly subclinical hypothyroidism. …”
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Technology-Dependent Rehabilitation Involving Action Observation and Movement Imagery for Adults with Stroke: Can It Work? Feasibility of Self-Led Therapy for Upper Limb Rehabilita... by Sheree A. McCormick, Christopher Ireland, Abebaw M. Yohannes, Paul S. Holmes

“…The data suggest a definitive trial is feasible, additional strategies to improve recruitment should be considered. Outcome measures aligned with the residual motor function of participants are required.…”
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Elucidating the role of KLRD1 in coronary atherosclerosis: harnessing bioinformatics and machine learning to advance understanding by Huan Liang, Xiao Liang, Man Zheng, Shoudong Wang

“…KLRD1 is a gene that encodes a protein involved in the immune system, specifically in the function of natural killer (NK) cells. Methods KLRD1 was identified as a focal point through an integrative analysis of DEGs across multiple datasets (GSE43292 and GSE9820) from the GEO database, aligned with immune-related gene sets from the ImmPort database. …”
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Individual muscle strengths in rehabilitation outcomes of distal radius fracture by Lunjian Li, Xuanchi Liu, Lihai Zhang

“…Based on the scaling function, the corresponding personalized musculoskeletal models can simulate grip forces that align well with experiment observations. …”
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Status assessment and management strategy of a large bridge based on massive real time data by Feng Zhou, Zhihao Cui

“…Additionally, the frequency response function, unit pulse response function, and covariance-related functions are utilized to derive the modal parameters of the structure during dynamic load testing. …”
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Effect of the Pes Planus on Vertical Jump Height and Lower Extremity Muscle Activation in Gymnasts by Tamer Çankaya, Nurcan Contarlı

“…Especially, lower extremity alignment can affect successful performance in gymnasts (6). …”
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