Bioprinting of GelMA-Based Hydrogels to Aid in Creation of Biomimetic 3D Models for Glioblastoma by Kaitlyn Ann Rose Schroyer, Kylie Marie Schmitz, Gunjeeta Raheja, Bin Su, Justin D. Lathia, Liqun Ning

“…Biocompatibility testing was performed via live/dead and AlamarBlue analyses using GBM cells (both commercial cell lines and patient-derived cell lines) encapsulated in the constructs, along with immunohistochemistry staining to understand how ECM properties altered the functions of GBM cells. …”
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Development of a human colorectal carcinoma cell-based platform for studying inducible nitric oxide synthase expression and nitric oxide signaling dynamics by Xi Chen, Elizabeth A. Grimm, Yong Qin

“…Treatment with selective iNOS inhibitors significantly reduced nitrite accumulation, confirming the functional activity of iNOS and the model’s applicability for pharmacologic evaluation of NO-modulatory compounds.DiscussionOur findings establish the DLD-1 cell line as a reproducible and well-controlled in vitro system for studying inducible iNOS expression and downstream NO/RNS signaling in human epithelial cancer cells. …”
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Interferon-induced factor 16 is essential in metastatic melanoma to maintain STING levels and the immune responses upon IFN-γ response pathway activation by Yoshinori Hayashi, Yuta Kobayashi, Qiang Yu, Dave Hoon, Matias A Bustos

“…The link between IFI16 and STING signaling pathway on IFN-γ stimulation and the connection to ICIs response remains not completely understood.Methods Deconvolution analyses were performed using the TCGA-SKCM, GSE91061, and PRJEB23709 public RNA sequencing (RNA-seq) data sets that contained RNA-seq for patients with MM. Functional assays combined with cytokine arrays were performed using MM cell lines to validate in silico data. …”
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Towards Parkinson’s Disease Detection Through Analysis of Everyday Handwriting by Jeferson David Gallo-Aristizabal, Daniel Escobar-Grisales, Cristian David Ríos-Urrego, Jesús Francisco Vargas-Bonilla, Adolfo M. García, Juan Rafael Orozco-Arroyave

“…Features extracted from time-dependent signals are represented following two strategies, one based on statistical functionals and the other one based on creating Gaussian Mixture Models (GMMs). …”
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ISGylation and E3 ubiquitin ligases: an Atlantic salmon genetic perspective by Unni Grimholt, Hilde Sindre, Arvind Y. M. Sundaram, Arvind Y. M. Sundaram

“…Our results highlight the need for functional studies to clarify the roles of these candidates.…”
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Enhancing rapid nitrogen freezer performance for Litchi fruit: a Taguchi-based approach to reduce cracking, time, and nitrogen consumption by Mohamed Anwer Abdeen, Zeyong Zheng, Xiaojin Cheng, Baiqing Yu, Chongyang Han, Yong Cao, Wenquan Huang, Ali Salem, Alaa Awny, Weibin Wu

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Bibliographic Cluster Analysis and Qualitative Research of Male Consumer Trend Groups in Hungary by Kata FÖLDI, Róbert Sándor SZŰCS, Katalin VARGÁNÉ CSOBÁN

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Decolonizing Knowledge and Academic Practices through collaborative methodology: Reflections on Collaborative filmmaking with Indigenous Students in the Peruvian Amazon by Jorge Ruiz Zevallos

“…Thus, underscoring that research and knowledge production should incorporate local knowledge from the Global South to continue its adaptable line (Finck Carrales, 2021).…”
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New American unilateralism by Đurković Miša

“…Having that in mind, it seems possible to predict that the strategy of the next president will probably go along the same lines and unilateralism will keep on being practiced as long as the world functions according to the unipolar model, with US as a global hegemon.…”
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Territorial barriers in urban environments: Conceptualisation of the term and assessment methodology (case study of the central area of Perm) by Volkov, Stanislav Andreevich, Merkushev, Sergey A., Tarantin, Mikhail Romanovich

“…Problematic segments are characteristic of zones with changing functions. Conclusions. The proposed methodology allowed for a more objective characterisation of boundary types, clarification of their functional features, and the development of recommendations for altering specific boundary segments. …”
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Donkey whey proteins ameliorate dextran sulfate sodium-induced ulcerative colitis in mice by downregulating the S100A8-TRAF6-NF-κB axis-mediated inflammatory response by Mohan Li, Qilong Li, Rayhnigul Abdlla, Jiali Chen, Xiqing Yue, Siew Young Quek

“…In addition, DWPs significantly decreased NF-κB and CD86 levels more than BWPs or the negative control in both LPS-stimulated human peripheral blood mononuclear cells or cell lines. These findings indicate that DWPs comprise a promising anti-colitis functional food, and this work has established a foundation for future research on these compounds.…”
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Network analyses identify liver‐specific targets for treating liver diseases by Sunjae Lee, Cheng Zhang, Zhengtao Liu, Martina Klevstig, Bani Mukhopadhyay, Mattias Bergentall, Resat Cinar, Marcus Ståhlman, Natasha Sikanic, Joshua K Park, Sumit Deshmukh, Azadeh M Harzandi, Tim Kuijpers, Morten Grøtli, Simon J Elsässer, Brian D Piening, Michael Snyder, Ulf Smith, Jens Nielsen, Fredrik Bäckhed, George Kunos, Mathias Uhlen, Jan Boren, Adil Mardinoglu

“…Experiments in human cancer cell lines, mouse liver samples, and primary human hepatocytes validated our predictions by demonstrating functional relationships between these liver genes, and showing that their inhibition decreases cell growth and liver fat content. …”
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ASSESSING SUSTAINABILITY OF SOCIAL AND ECONOMIC DEVELOPMENT OF THE REGION BASED ON INTEGRAL APPROACH by Natalia Yu. Sorokina

“…The article puts forward an approach to assessing sustainability of regional development through using methodology of the integral approach, which implies a joint use of morphological, dynamic and functional research approaches. The author advances an economic and mathematic model of the process of sustainable social and economic development of the region and a system of figures that can trace the impact of legal, organizational, economic and social factors on sustainability of the regional development. …”
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L’expérience touristique à l’ère numérique by Eric OLMEDO, Maxime FERAILLE, Dafinah AHMED HILMI, Eelco WATZEMA, Giles GILLISON, Jignesh JITENDRA JAMNADAS, Mas Ayu PUTERI ABDUL KADIR, Alicia ARRIBAS

“…A quantitative survey with 348 respondents, combined with qualitative data gathered from 11 experts, enabled us to anchor functionalities of the future application conceptually. …”
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Role of Imaging in Cardiomyopathies by Vincenzo Castiglione, Alberto Aimo, Giancarlo Todiere, Andrea Barison, Iacopo Fabiani, Giorgia Panichella, Dario Genovesi, Lucrezia Bonino, Alberto Clemente, Filippo Cademartiri, Alberto Giannoni, Claudio Passino, Michele Emdin, Giuseppe Vergaro

“…Findings from imaging techniques should always be integrated with data from the clinical, electrocardiographic, biomarker, genetic and functional evaluation to pursue an individualised approach to patients with cardiomyopathy.…”
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Scenariusz filmowy i jego odmiany: Studium przedmiotu. by Marek Hendrykowski

“…In his study, Marek Hendrykowski examines the meaning and functions of all crucial terms connected with film script and screenplay, among them: concept, log line, story, synopsis, treatment, draft, first draft, storyboard, director’s draft, final script and shooting script. …”
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Diagnosis and therapy of obsessive-compulsive spectrum disorders in general medical and neurological practice by D. S. Petelin, A. N. Gamirova, O. Yu. Sorokina, D. V. Troshina, S. A. Semin, M. Sh. Boltueva, B. A. Volel

“…This review discusses the prevalence of obsessive-compulsive spectrum disorders, their negative impact on the level of functioning of patients, comorbidity with other mental disorders, diagnosis and differential diagnosis. …”
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Synthesis of Bioactive Three-dimensional Silicon-oxide Nanofibrous Structures on the Silicon Substrate for Bionic Devices’ Fabrication by Candace Colpitts, Amirkianoosh Kiani

“…Bionic devices are implants that replace biological functions that have been lost due to damaged or lost tissue. …”
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Problems of prescribing nonsteroidal anti-inflammatory drugs for reproductive-aged women with ankylosing spondylitis by O. A. Krichevskaya, T. V. Dubinina, A. E. Karateev

“…Nonsteroidal anti-inflammatory drugs (NSAIDs) are the first-line medications for ankylosing spondylitis (AS); their action is associated with blockade of the enzyme cyclooxygenase 2 and with a mediated decrease in the synthesis of prostaglandins (PGs). …”
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Making It Trustable: Acoustic-Based Signcryption Mutual Authentication for Multiwearable Devices by Shuhua Zhu, Xiaojie Li, Chunsheng Zhu, Lei Shu, Wei Sun

“…In order to provide secure communication, mutually trusted authentication becomes the first line of protection to guard our personal information. …”
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