Screening and analysis of programmed cell death related genes and targeted drugs in sepsis by Juanjuan Song, Kairui Ren, Yi Wang, Dexin Zhang, Lin Sun, Zhiqiang Tang, Lili Zhang, Ying Deng

“…Conclusions Through bioinformatics approaches, this study successfully identified five genes (IRAK3, S100A9, TXN, NFATC2, and GSTO1) associated with programmed cell death in the context of sepsis. This research identified seven candidate drugs for sepsis treatment and established a methodological framework for predicting biomarkers and drug targets that could be applicable to other diseases.…”
Get full text

Developing a bespoke capacity-strengthening program for the clinical pharmacy profession in India by Dr Vrinda Nampoothiri, Mr Muhammed Rashid, Dr Dena Van Den Bergh, Dr Esmita Charani, Dr Mohamed Hisham

“…Our study aims to develop a competency framework and professional development guide for clinical pharmacists in India. …”
Get full text

Effectiveness of wellness program interventions to improve physician wellness: a systematic review by Nikola Kolobaric, Benjamin Milone, Maria Salman, Amos Buh, Nandini Biyani, Gamal Wafy, Stephen G Fung, Mekaylah Scott, Rohan Kiska, Rachel Kang, Kathryn Lee, Sarah Syed, Maya Gibb, Shan Dhaliwal, Daniel Myran, Courtney Maskerine, Pierre Antoine Brown, Ayub Akbari, Gregory L. Hundemer, Peter Tanuseputro, Deena Fremont, Edward Spilg, Manish M. Sood

“…Abstract Background Physician wellness programs are being implemented to offset rises in physician burnout. …”
Get full text

The evolution of Canada's first pediatric hospital program specializing in child sex trafficking by Corry Azzopardi, Romy Cho, Jasmine Eliav, Heather Farina, Cynthia S.-Y. Shih, Jennifer N. Smith, Tanya D. Smith

“…Trauma-informed pediatric health care, embedded in a systems of care framework, can help to improve the health and safety of child sex trafficking victims and survivors. …”
Get full text

Evaluation methods in tuberculosis control programs in resource-limited settings: a scoping review by Ndukong N. Ndi, M. Samje, K. Tabe, Mary A. Suh

“…Objectives This scoping review aimed to: explore the types of evaluation frameworks and methods used, assess implementation level and evaluations, and identify gaps in TB program evaluation across RLSs. …”
Get full text

Paramedic educational programs maintain entry level competency throughout the COVID‐19 pandemic by Shea L. vanden Bergh, Lakeshia T. Logan, Jonathan R. Powell, Christopher B. Gage, Kathryn R. Crawford, Lisa Collard, Michael G. Miller, Ashish R. Panchal

“…These reports contain detailed program components and measures of program success. …”
Get full text

Evaluating Community Violence Intervention Programs: A Scoping Review Synthesizing Methods and Measures by Meron Girma MPH, Julia Schleimer MPH, PhD, Astrid Aveledo MPA, Ayah Mustafa BA, Camerin Rencken MPH, PhD, Carolyn Thurston MA, Deepika Nehra MD, Kris Torset BA, Kristian Jones MA, PhD, Laura Johnson MSW, Lauren Polansky MLS, MPH, Olivia McCollum MPH, Orlando Ames AA, Rachel Ross MPH, Sam Decker MBA, Stephanie Taylor MPA, Tarrell Harrison BAS, Vivian Lyons MPH, PhD, Zaheed Lynch BA, Ali Rowhani-Rahbar MPH, MD, PhD

“…By including process and outcome measures, including community-level units of analysis in addition to the typical individual-level ones, employing asset-based frameworks, and actively involving community voices, future research can more effectively assess the implementation and impacts of CVI programs.…”
Get full text

The potential of programme theory in bridging the evidence into practice gap in implementation science: a worked example of integrating palliative care into heart failure managemen... by Tracey McConnell, Carolyn Blair, Joanne Reid, Geoff Wong

“…In summary, our paper challenges the growing reliance on implementation theories, models and frameworks as the only starting point for research in this field, and we argue that realist programme theory may be equally useful.…”
Get full text

Self-Management Analysis in Chronic Conditions (SMACC) checklist: an international consensus-based tool to develop, compare and evaluate self-management support programmes by Cynthia Engels, Dominique Van de Velde, Ton Satink, Ursula Costa, Daniela Senn, Patricia De Vriendt, Aileen Bergström, Maria Rodriguez-Bailon, Timothy Moreels, Ellen Cruyt, Stijn De Baets, Lore Andries, Magelien Arts-Tielemans, Kyara Boete, Iris Bormans, Hanne Declercq, Sari Dekelver, Virginie Dekyvere, Eva Delooz, Sam Helderweirt, Mike Jarrey, Anneleen Lenaerts, Anneleen Leyman, Kee Hean Lim, Louise Meynen, Freya Schoenmakers, Lise Slembrouck, Emma Van Meensel, Dani Vangenechten, Bram Van Paepeghem

“…In round 2, 3 of the 4 remaining items reached consensus, 1 last item was retained based on highly recurring feedback.Conclusions The SMACC checklist was considered a valid and comprehensive tool to aid the development, evaluation and comparison of self-management support programmes. It was acknowledged as a useful instrument to supplement existing frameworks and was seen as feasible to implement in both research and clinical settings. …”
Get full text

Effectiveness-implementation hybrid type 2 trial evaluating two psychoeducational programmes for severe hypoglycaemia in type 1 diabetes: implementation study protocol by Nick Sevdalis, Tayana Soukup, Ioannis Bakolis, Stephanie A Amiel, Emma Lauretta Smith, Louise Hull, Andy Healey, PWD Group

“…While both programmes are aimed at reducing hypoglycaemia, SH and IAH, it is the former that integrates behavioural change techniques.The aim of the current (implementation) study is to evaluate delivery of both HARPdoc and BGAT and explore associations between implementation outcomes and trial endpoints; as well as to develop an evidence-based implementation blueprint to guide implementation, sustainment and scale-up of the effective programmes.Methods and analysis Guided by the implementation science tools, frameworks, methods and principles, the current study was designed through a series of focus groups (n=11) with the key intervention stakeholders (n=28)—including (1) individuals with lived experience of T1D, IAH and a pilot version of the HARPdoc (n=6) and (2) diabetes healthcare professionals (n=22). …”
Get full text

A C-Based Framework for Low-Cost Real-Time Embedded Systems by Ivan Cibrario Bertolotti

“…This paper presents a framework that enables programmers to deploy embedded real-time firmware of Internet of Things (IoT) devices more conveniently than using plain C/C++-language programming, by abstracting away from low-level details and the ad hoc management of multiple, diverse network technologies. …”
Get full text

Regulating antimicrobial resistance in the environment: analysis of Thailand legal framework and areas for reinforcement by Angkana Lekagul, Saowapa Khotchalai, Wanwisa Kaewkhankhaeng, Mary Gordoncillo, Fuangfa Utrarachkij, Viroj Tangcharoensathien

Get full text

An FPGA-Based Quantum Computing Emulation Framework Based on Serial-Parallel Architecture by Y. H. Lee, M. Khalil-Hani, M. N. Marsono

“…The proposed work contributes to the formulation of a proof-of-concept baseline FPGA emulation framework with optimization on datapath designs that can be extended to emulate practical large-scale quantum circuits.…”
Get full text

Pelatihan Media Pembelajaran Assemblr Edu Berbasis Augmented Reality Terintegrasi Framework by Oktaviana Nirmala Purba, Sri Rahmah Dewi Saragih, Dicky Apdillah

“…Program Kemitraan Masyarakat (PKM) dilakukan peneliti di SMP Swasta Triyadikayasa. …”
Get full text

A rationale and framework for sharing mindfulness in trauma-dense communities in South Africa by Simon Whitesman

Get full text

Green Port Industry to Support the Offshore Wind Sector: A Proposal Framework by Monalisa Godeiro, Mario González, Dylan Jones, Negar Akbari, Gabriela Nascimento, David Melo, Rafael Vasconcelos, Andressa Santiso, Luana Nogueira, Mariana Almeida, José Toledo

Get full text

Cationic covalent organic framework for the fluorescent sensing and cooperative adsorption of perfluorooctanoic acid by Asmaa Jrad, Gobinda Das, Nour Alkhatib, Thirumurugan Prakasam, Farah Benyettou, Sabu Varghese, Felipe Gándara, Mark Olson, Serdal Kirmizialtin, Ali Trabolsi

Get full text

A Discrete-Event Based Power Management System Framework for AC Microgrids by Paolo C. Erazo Huera, Thamiris B. de Paula, João M. T. do Amaral, Thiago M. Tuxi, Gustavo S. Viana, Emanuel L. van Emmerik, Robson F. S. Dias

Get full text

AlleleSeq: analysis of allele‐specific expression and binding in a network framework by Joel Rozowsky, Alexej Abyzov, Jing Wang, Pedro Alves, Debasish Raha, Arif Harmanci, Jing Leng, Robert Bjornson, Yong Kong, Naoki Kitabayashi, Nitin Bhardwaj, Mark Rubin, Michael Snyder, Mark Gerstein

Get full text

PyBrook—A Python framework for processing and visualising real-time data by Michał Rokita, Mateusz Modrzejewski, Przemysław Rokita

“…In this paper, we present PyBrook - an original real-time cloud computing framework for the Internet of Things. PyBrook enables users to define complex data processing models declaratively, using the Python programming language. …”
Get full text