Self-adaptive fuzzing optimization method based on distribution divergence by XU Hang, JI Jiangan, MA Zheyu, ZHANG Chao

“…The experimental results show that on the benchmark FuzzBench, the code coverage speed and overall coverage achieved by the prototype are significantly better than those of the baseline fuzzer AFL++ and HavocMAB, and better results are achieved on most benchmarks compared to CmpLog. …”
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Advancing early detection of organ damage and cardiovascular risk prevention: the Suzhou cardiometabolic health study protocol - exploring the role of oral microbiome and metabolic... by Mengmeng Zhu, Mengmeng Zhu, Yiwen Li, Wenting Wang, Longkun Liu, Wenwu Liu, Jiayu Yu, Qian Xu, Jing Cui, Yanfei Liu, Keji Chen, Yue Liu, Yue Liu

“…The study will be conducted in Suzhou City, Jiangsu Province, China, planning to include 5000-6000 eligible subjects, with inclusion criteria of age ≥18 years, excluding individuals with a history of CVD and other serious diseases. Baseline assessment includes demographic information, lifestyle (including dietary patterns), medical history, physical examination, and collection of tongue coating microbiota samples. …”
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Fault and Severity Diagnosis Using Deep Learning for Self-Organizing Networks With Imbalanced and Small Datasets by Hsin-Chang Tsai, Ming-Chun Lee, Chao-Hao Hsu

“…Results show that our approaches can effectively diagnose the faults and their severity and outperform the baseline approaches under imbalanced and small datasets.…”
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Neuromuscular and structural tendon adaptations after 6 weeks of either concentric or eccentric exercise in individuals with non-insertional Achilles tendinopathy: protocol for a r... by Deborah Falla, Eduardo Martinez-Valdes, Ignacio Contreras-Hernandez

“…Additionally, we want to compare these variables at baseline between individuals with NIAT and asymptomatic controls.Methods and analysis A total of 26 individuals with chronic (>3 months) NIAT and 13 healthy controls will participate in the study. …”
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The population structure and habitat use of resident of Mandarin Duck (Aix galericulata) in Wu River (Southwest China) by Canshi Hu

“…This information will contribute to provide baseline knowledge on the resident population of Mandarin ducks, and enhance understanding of the causes and consequences of breeding partial migration.…”
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Study on the correlation between carotid plaque calcification types and acute ischemic stroke by Tianyu Chu, Zhongping Guo, Yonggang Zhang, Ying Liu, Yan Gu

“…This could provide new insights into the clinical evaluation and treatment of ischemic stroke.MethodsThis study obtained information on patients undergoing head and neck CTA examinations at the First People's Hospital of Lianyungang between September 2022 and August 2023 to investigate the clinical differences in baseline data between the acute ischemic stroke and control groups. …”
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Evaluation of the Results of Patients Who Were Treated with Laparoscopic Simple Tunnel Hysterosacropexy Method to Prevent Uterine Prolapse: A New Approach by Erdal Seker, Evindar Elci

“…There were not any complications during the intraoperative period and postoperative follow-ups. During the first six-month follow-up, there were not any recurrence of prolapse. …”
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Enhancing foster care relationships through attachment-based intervention: the safe families study protocol, a randomized controlled trial of the circle of security parenting progr... by Mathieu Pereira, Lauriane Sedes, Emilie Gadéa, Rebecca Shankland

“…Discussion This study is the first to evaluate the COS-P program for foster carers in France. …”
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Methods to address functional unblinding of raters in CNS trials by Steven D. Targum, William P. Horan, Vicki G. Davis, Alan Breier, Stephen K. Brannan

“…Remote ratings closely replicated 575 available “paired” site-based PANSS total scores at baseline and endpoint (intraclass correlation coefficient = 0.88 and 0.93, respectively). …”
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Impact of a Novel Insulin Management Service on Non-insulin Pharmaceutical Expenses by John E. Schneider, Anjani Parikh, Ivana Stojanovic

“…A prospective cost analysis was conducted using data from enrolled patients who completed the first 90 days of follow up. **Results:** Of the 192 patients who completed the 90-day study period, 54 (28.13%) were prescribed one or more expensive medications at baseline, but 45 (83.33%) of those patients were eligible for medication discontinuation after 90 days. …”
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Screening for coronary artery disease among cancer survivors: rationale and design of the REDEEM-CAD study by Cheng Hwee Soh, Joel Smith, Shristy Shrestha, Mark Nolan, Joshua Wong, Nitesh Nerlekar, Thomas H. Marwick

“…Secondary endpoint includes the absolute change in total coronary plaque volume over 24 months among those imaged at baseline and follow-up. Summary The REDEEM-CAD study will be the first study to systematically evaluate risk of CAD in cancer survivors, and subsequent responsiveness to coronary risk reduction. …”
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Real-World Assessment of Weight Change in People with HIV-1 After Initiating Integrase Strand Transfer Inhibitors or Protease Inhibitors by Yen-Wen Chen, Helene Hardy, Christopher D. Pericone, Wing Chow

“…Adult PLWH who initiated INSTI- or PI-based regimens between March 1, 2016 and June 30, 2018 (index date was the first INSTI or PI prescription in this period) with ≥12-month baseline and follow-up periods, ≥1 weight measure during each period, and no prior antiretroviral use were included. …”
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PIVKA-II as a surrogate biomarker for therapeutic response in Non-AFP-secreting hepatocellular carcinoma by San-Chi Chen, Hsiang-Ling Ho, Chien-An Liu, Yi‑Ping Hung, Nai-Jung Chiang, Ming‑Huang Chen, Yee Chao, Muh-Hwa Yang

“…Methods Patients with unresectable HCC undergoing systemic therapy were enrolled. Baseline imaging and PIVKA-II levels were recorded. …”
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Patient-reported Outcomes and Muscle Strength after a Physiotherapy-led Exercise and Support Brace Intervention in Patients with Acute Injury of the Posterior Cruciate Ligament: A... by Randi Gram Rasmussen, Julie Sandell Jacobsen, Birgitte Blaabjerg, Torsten Grønbæk Nielsen, Lene Lindberg Miller, Martin Lind

“… # Results The IKDC-SKF score improved 28 (95%CI 24-33) IKDC points from baseline to two-year follow-up. Isometric knee flexion strength of the injured knee increased 0.18 (95%CI 0.11-0.25) Nm/kg from 16 weeks after diagnosis to one-year follow-up, corresponding to an increase of 16%. …”
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Economic Burden of HIV in a Commercially Insured Population in the United States by Cindy Y. Chen, Prina Donga, Alicia K. Campbell, Babafemi Taiwo

“…Descriptive analyses were conducted to assess baseline demographics and clinical characteristics, and all-cause and HIV-related HRU and costs per patient per month (PPPM) during follow-up. …”
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Long-term cardiac MRI follow up of MANTICORE (Multidisciplinary Approach to Novel Therapies in Cardio-Oncology REsearch) by Dina Labib, Mark Haykowsky, Emer Sonnex, John R. Mackey, Richard B. Thompson, D. Ian Paterson, Edith Pituskin

“…We posit that the presence of HER2 overexpressing breast cancer influenced hypertrophic changes to cardiac geometry observed at baseline and one year, which resolved after completing HER2-blocking treatment. …”
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Clinical, immune and genetic risk factors of malaria-associated acute kidney injury in Zambian children: A study protocol. by Chisambo Mwaba, Sody Munsaka, David Mwakazanga, David Rutagwerae, Owen Ngalamika, Suzanna Mwanza, Mignon McCulloch, Evans Mpabalwani

“…Serum creatinine is collected on Day 1 within 24 hours of admission, on Day 3 and then again on discharge or day 7, whichever comes sooner. Baseline biomarker concentrations will be determined using the Luminex multiplex Elisa system or high-sensitivity ELISA. …”
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Functional MRI-guided microsurgery of intracranial arteriovenous malformations: study protocol for a randomised controlled trial by Shuo Wang, Yuanli Zhao, Jun Wu, Bing Zhao, Yong Cao

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BuDDI: Bulk Deconvolution with Domain Invariance to predict cell-type-specific perturbations from bulk. by Natalie R Davidson, Fan Zhang, Casey S Greene

“…We evaluated BuDDI's performance on simulated and real data with experimental designs of increasing complexity. We first validated that BuDDI could learn domain invariant latent spaces on data with matched samples across each source of variability. …”
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Development of an mPBPK machine learning framework for early target pharmacology assessment of biotherapeutics by Krutika Patidar, Nikhil Pillai, Saroj Dhakal, Lindsay B. Avery, Panteleimon D. Mavroudis

“….), and virtual target candidates with varying characteristics (baseline expression, half-life, etc.) to unravel rules for antibody drug candidate selection that achieve favorable drug-target interaction, which is defined by target occupancy (TO) percentage. …”
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