Establishment and validation of a population pharmacokinetic model for apatinib in patients with tumors by Li’an Zuo, Jing Ling, Nan Hu, Rong Chen

“…Conclusion Our study successfully established a PPK model for apatinib in oncology patients, revealing that liver function status and co-administered drug types significantly impacted apatinib CL/F. This finding underscored the potential necessity for dose adjustments to optimize efficacy, particularly in patients undergoing different chemotherapy regimens involving apatinib.…”
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Simulation of the Operation of a Borehole Groundwater Intake with an Annular Prefabricated Conduit by V. V. Veremenyuk, V. V. Ivashechkin, V. I. Krytskaya

“…The absence of algorithms for calculating the ring prefabricated conduit with non-fixed flow rates at the well connection points complicates the hydraulic calculation, and, hence, finding the optimal water intake option. The article presents an algorithm for the hydraulic calculation of a water intake with a single-ring prefabricated conduit, which is based on the equation for the equality of pressure losses when water moves from the point of separation of two flows to the prefabricated unit along various paths and the continuity equation. …”
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Constructing multilayer PPI networks based on homologous proteins and integrating multiple PageRank to identify essential proteins by He Zhao, Huan Xu, Tao Wang, Guixia Liu

“…The MLPR model uses multiple PageRank methods to comprehensively consider homologous relationships across species and designs three key parameters to find the optimal combination that balances random walks within layers, global jumps, interlayer biases, and interspecies homologous relationships. …”
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Prevailing insights into anastomotic angles of surgically created arteriovenous fistulas: a literature review by Xinyang Li, Chong Liu, Haidi Hu

“…The anastomotic angles chosen for AVF creation are usually ones that surgeons find easiest to manually control. At present, many sources have confirmed that variations in anastomotic angle culminate in differing geometric parameters of perianastomotic blood vessels, thus affecting the AVF maturation process. …”
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Decoration of carbohydrate nanocomposite with silver nanoparticles for highly efficient adsorption of methylene blue and antimicrobial against human pathogens by Ahmed K. Saleh, Rasha Jame, Fatimah A. Alotaibi, Mahmoud A. Abdelaziz, Noha Omer

“…The formed nanocomposite might find applications in industrial and biomedical fields.…”
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Effect of Charcoal on the Quality of Vermicompost Produced With Water Hyacinth and Cow Manure by Solomon Girmay Berhe, Ali Seid, Berhanu Abraha Tsegay, Shinjiro Sato, Getahun Yemata Lule

“…However, in most of the results, there was no significant difference between T1 and T2. This finding suggests that the use of T2 (5.00%) charcoal addition enhances vermicompost quality to optimal maturity and stability.…”
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Development of Tracer Gas Method to Improve Indoor Air Quality: A Study on Ventilation Performance in Apartment Buildings in South Korea by Soo Man Lee, Sang Yoon Lee, Gil Tae Kim, Byung Chang Kwag

“…Therefore, this study reviews various standards, finding that these standards can be categorized into those evaluating the mechanical performance of ventilators and those assessing indoor ventilation performance. …”
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Performance of Sentiment Classification on Tweets of Clothing Brands by Muhammad Shafiq Jalani, Hu Ng, Timothy Tzen Vun Yap, Vik Tor Goh

“…Hyperparameter tuning was implemented by GridSearchCV to find the best parameters of classification models in order to optimize the best results.  …”
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ANALYSIS OF HEART RATE VARIABILITY IN PATIENTS WITH PERSISTENT ATRIAL FIBRILLATION by M. I. Fushtey, O. V. Soloviov, E. V. Sid’

“…The analysis of HRV allows you to make a more precise choice of drug and find it more optimal dose. Given the lack of uniform standards of HRV in patients with coronary artery disease should be analyzed the dynamics of these parameters during treatment compared with baseline data. …”
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Formation and stability of gold nanoparticles in colloids prepared by citrate method by N. V. Vityuk, A. M. Eremenko, N. M. Rusinchuk, V. Z. Lozovski, M. M. Lokshyn, V. S. Lysenko, Iu. P. Mukha

“…Comparative analyses of UV-vis spectra with DLS data by number, volume and intensity basis allowed to trace the changes in Au NPs colloid, find optimal experimental conditions and predict prolonged stability of colloids. …”
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Multiparametric Study of Water–Gas Shift and Hydrogen Separation Performance in Membrane Reactors Fed with Biomass-Derived Syngas by Nadia Cerone, Luca Contuzzi, Giuseppe Domenico Zito, Carmine Florio, Laura Fabbiano, Francesco Zimbardi

“…The rig consists of two Pd-Ag membrane permeator units and two Pd-Ag membrane reactor units for the water–gas shift (WGS) reaction, enabling a detailed and comprehensive analysis of its performance. The aim was to find the optimal conditions to maximize hydrogen production by WGS and its separation in a pure stream by varying the temperature, pressure, and steam-to-CO ratio (S/CO). …”
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Antithrombotic therapy for a case report of acute myocardial infarction after laparoscopic radical cystectomy by Zilong Wang, Zilong Wang, Zilong Wang, Zilong Wang, Huisheng Yuan, Junhao Chu, Shishuai Duan, Zhihui Zhang, Changze Song, Muwen Wang

“…Therefore, the necessity and optimal strategy for anticoagulation therapy in patients with acute myocardial infarction following radical cystectomy remains a subject of ongoing debate. …”
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The role of biomarkers of acute kidney injury in predicting functional outcomes of surgical treatment of patients with localized kidney cancer by I. O. Dementev, K. M. Nyushko, O. B. Karyakin, V. S. Chaikov, A. V. Troyanov, I. N. Zaborskii, E. O. Shchukina

“…An active study of this problem made it possible to find specific biomarkers that give the possibility to predict and diagnose acute renal injury in the early stages, to optimize the treatment strategy, to reduce the incidence of postoperative complications, and to shorten the period of postoperative rehabilitation. …”
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Biogas slurry topdressing enhances the comprehensive benefits of maize: New perspectives on grain filling process, yield, and endogenous microbiome by Xiaoyang Liang, Haitao Wang, Chuanjuan Wang, Junjie Qin, Xuefeng Qiu, Yongxing Wen, Jiandong Wang, Xurong Mei

“…Finding new approaches to enhance the comprehensive effects of maize has been the persistent pursuit of scientific researchers. …”
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Clinical and immunologic abnormalities in COVID-19 by A. K. Karibova, S. S. Akhmedkhanov, M. T. Kudae, H. M. Malaev

“…The results suggest that COVID-19 can provoke the development of immunological abnormalities that may subsequently lead to the development of an autoimmune diseases (AID). The optimal approach to prevention and early detection of AID in patients with coronavirus infection caused by SARS-CoV-2 is to monitor laboratory parameters – leukocyte count and CRP level. …”
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Features of the High Blood Pressure Daily Monitoring Indices in Patients with Different Degree of Systemic Lupus Erythematosus Activity by Abrahamovych U.

“…The detected regularities of BPDM help to optimize the treatment of arterial hypertension in patients with SLE.…”
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Individualization of tDCS intensity according to corticospinal excitability does not improve stimulation efficacy over the primary motor cortex by Etienne Sallard, Jaimie Lee Rohrbach, Catherine Brandner, Nicolas Place, Jérôme Barral

“…This calls for further investigations to find the optimal tDCS setting to reduce the inconsistency in the results and obtain reproducible effects.…”
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Reducing process time of PV module lamination by using double-side heating system by Sraisth, Mansour Djamel Eddine, Öz Aksel Kaan, Gebhardt Paul, Klaus Daniel, Wellens Christine

“…Non-optimized encapsulation parameters, set during the lamination process, can be a cause of multiple failure modes for PV modules in the field. …”
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BEHAVIOR OF RARE-EARTH METALS IN HYDROMETALLURGICAL PROCESSING OF PYROCHLOR-MONAZITE-GOETHITE ORES by N. A. Permyakova, E. I. Lysakova, S. I. Anufrieva, E. G. Likhnikevich

“…The article is dedicated to finding out the specific features of the behavior of rare-earth metals in hydrometallurgical processing of pyrochlore-monazite-goetite ores of the Chuktukonsky ore field is shown in the work. …”
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Development of an Algorithm for Clustering Cardiac ECG Signals with Post-Correction for Long-Term ECG Monitoring by I. A. Kondratyeva, A. S. Krasichkov, O. A. Stancheva, E. Mbazumutima, F. Shikema, E. M.

“…The presence of a small number of reference cardiac signal complexes, obtained through ECG processing using the proposed algorithm, allows physicians to optimize the process of ECG analysis. The as- obtained information serves as a basis for assessing dynamic changes in the shape and other parameters of cardiac signals for both a particular patient and groups of patients. …”
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