A bayesian network model for neurocognitive disorders digital screening in Chinese population: development and validation study by Yifan Yu, Shuaijie Zhang, Hongkai Li, Fuzhong Xue

“…Gender and the top 30 variables with the highest coefficient of determination () in explaining the variance in NCD status were retained for model construction. Subsequently, the optimal network structure was identified using the Tabu search algorithm guided by Bayesian Information Criterion, with parameters estimated by maximum likelihood estimation. …”
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The Mechanism of Aniline Blue Degradation by Short-Chain Dehydrogenase (<i>SDRz</i>) in <i>Comamonas testosteroni</i> by Chuanzhi Zhang, Yong Huang, Jiaxin He, Lei He, Jinyuan Zhang, Lijing Yu, Elshan Musazade, Edmund Maser, Guangming Xiong, Miao Xu, Liquan Guo

“…Under optimal conditions, the rSDRz achieved a degradation efficiency of 62.17% for aniline blue. …”
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Impact of CYP3A5 1* and 3* single nucleotide variants on tacrolimus pharmacokinetics and graft rejection risk in pediatric kidney transplant patients by Lesly Yanira Xajil-Ramos, Lesly Yanira Xajil-Ramos, Lesly Yanira Xajil-Ramos, Lesly Yanira Xajil-Ramos, Jesús Alonso Gándara-Mireles, Jesús Alonso Gándara-Mireles, Rodrigo José Vargas Rosales, Rodrigo José Vargas Rosales, Rodrigo José Vargas Rosales, Oscar Kevin Sánchez García, Andrea Mariela Ruano Toledo, Amy Kateleen Aldana de la Cruz, Ismael Lares-Asseff, Ismael Lares-Asseff, Leslie Patrón-Romero, Horacio Almanza-Reyes, Randall Lou-Meda

“…Increased drug exposure was associated with a higher incidence of rejection events, whereas CYP3A5 expression correlated with a reduced rate of rejection. These findings underscore the clinical utility of CYP3A5 genotyping for optimizing tacrolimus dosing strategies. …”
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Threshold Effects of Nitrogen Fertilization Rates on Growth and Essential Oil Yield with Component Regulation in <i>Cinnamomum camphora</i> var. <i>linaloolifera</i> by Zhirong Liu, Xinyi Chen, Jiao Zhao, Luyuan Sun, Jian Guo, Yangyang Shao, Jia Liu, Lei Zhong, Haiyan Zhang, Yanbo Wang, Jie Zhang

“…The determination of an optimal nitrogen (N) fertilization rate is critical for the sustainable large-scale cultivation of <i>Cinnamomum camphora</i> var. …”
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A hybrid approach to predicting and classifying dental impaction: integrating regularized regression and XG boost methods by Asok Mathew, Pradeep K. Yadalam, Ahmed Radeideh, Shrouk Hady, Rona Swed, Reyyan Cheema, Majd Mousa AL-Mohammad, Mohammed Alsaegh, SR Shetty

“…Enhancing data quality, refining feature selection, and using advanced modeling techniques are crucial for improving predictive capabilities. The findings can help practitioners optimize treatments and reduce potential complications.…”
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Performance, Agro-Morphological, and Quality Traits of Durum Wheat (<i>Triticum turgidum</i> L. ssp. <i>durum</i> Desf.) Germplasm: A Case Study in Jemâa Shaïm, Morocco by Khadija Manhou, Mona Taghouti, Rachid Moussadek, Houda Elyacoubi, Sahar Bennani, Abdelmjid Zouahri, Ahmed Ghanimi, Hatim Sanad, Majda Oueld Lhaj, Driss Hmouni, Houria Dakak

“…The productivity and resilience of durum wheat have been enhanced through the selection of accessions, optimizing agronomic and quality traits to address environmental challenges. …”
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Development and validation of a novel prognostic model to predict 1-year post-transplant mortality for acute-on-chronic hepatitis B liver failure: a nationwide, multicentre, cohort... by Li Zhuang, Yimou Lin, Yu Jia, Jun Fang, Yujian Zheng, Taishi Fang, Meiching Ong, Aibo Mu, Jiaxing Zhu, Mengchao Wang, Dong Zhao, Feiwen Deng, Qiucheng Lei, Leibo Xu, Zuozhong Yang, Qiang Sun, Wei Qu, Chenwei Xu, Zhijun Zhu, Chuanjiang Li, Hanyu Jiang, Jimin Liu, Xiaoshun He, Shusen Zheng, Zhiyong Guo, Qi Ling

“…Interpretation: The HALT model showed superior predictive ability over eight current models and may help for LT candidate selection and optimal organ allocation. Though the findings need to be verified in prospective studies and among different patient populations. …”
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Antioxidant System Activity in Roots and Shoots of Bean Cultivars in Response to Seed Treatment with Auxin as a Potential Model of Interaction with Endophytic Bacteria by Svetlana Garipova, Viktoriia Matyunina, Aelita Chistoedova, Oksana Markova, Alsu Lubyanova, Oksana Lastochkina, Ekaterina Pedash, Azamat Avalbaev, Lyudmila Pusenkova

“…(bean): Ufimskaya, Elsa, and Zolotistaya. The findings showed dose-dependent and cultivar-specific responses of 7-day-old bean seedlings to exogenous IAA. …”
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Evaluation of a fermented palm kernel meal as a prebiotic for enhancing immune response in Indonesian red claw crayfish (Cherax quadricarinatus) by Diki Danar Tri Winanti, Hilma Nahwa Firdausi, Maulid Wahid Yusup, Putu Cinthia Delis, Agus Setyawan, Yeni Elisdiana, Hilma Putri Fidyandini, Muhammad Kholiqul Amiin, Ari Widodo

“…PO and SOD activities significantly increased on days 5 and 14, respectively, with optimal responses at the highest dietary FPKM inclusion. …”
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Vaccination with inactivated SARS-CoV-2 vaccine TURKOVAC induces durable humoral and cellular immune responses up to 8 months by Seçil Yılmaz, Ahmet Eken, Ahmet Eken, Zafer Sezer, Zafer Sezer, Burcu Şen Bağcı, Serife Erdem, Medine Doğan Sarıkaya, Busra Kaplan, Busra Kaplan, Ahmet Inal, Ahmet Inal, Adnan Bayram, Gamze Kalın Unuvar, Gokmen Zararsız, Serra İlayda Yerlitas, Nuri Cakir, Shaikh Terkis Islam Pavel, Muhammet Ali Uygut, Hazel Yetiskin, Ates Kara, Aykut Ozdarendeli, Aykut Ozdarendeli

“…Additionally, the impact of two versus three doses of vaccination on these parameters was analyzed.MethodsVolunteers (n = 80) received two or three doses of TURKOVAC. …”
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Melatonin Alleviates Photosynthetic Injury in Tomato Seedlings Subjected to Salt Stress via OJIP Chlorophyll Fluorescence Kinetics by Xianjun Chen, Xiaofeng Liu, Yundan Cong, Yao Jiang, Jianwei Zhang, Qin Yang, Huiying Liu

“…Conversely, the injection of exogenous p-CPA exacerbated salt stress-related damage to the photosystem of tomato seedlings and diminished the beneficial effects of MT. The findings suggest that exogenous MT mitigates salt stress-induced photoinhibition by (1) modulating endogenous MT concentrations, (2) augmenting PSII reaction center functionality, (3) safeguarding the oxygen-evolving complex (OEC), (4) reinstating PSI redox potential, (5) facilitating photosynthetic electron transport, and (6) optimizing energy absorption and dissipation. …”
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Comparison of Automated Point-of-Care Gram Stainer (PoCGS^®) and Manual Staining by Goh Ohji, Kenichiro Ohnuma, Kei Furui Ebisawa, Mari Kusuki, Shunkichi Ikegaki, Hiroaki Ozaki, Reiichi Ariizumi, Masakazu Nakajima, Makoto Taketani

“…Future developments will focus on optimizing staining parameters and expanding its application to other clinical sample types, ensuring robustness and broader usability in diverse healthcare settings.…”
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Effects of virtual reality-based interventions on cognitive function, emotional state, and quality of life in patients with mild cognitive impairment: a meta-analysis by Xiaohan Li, Yuting Zhang, Lifeng Tang, Lifeng Tang, Lin Ye, Min Tang

“…Subgroup analyses were stratified by VR parameters (immersion level, duration, session, and frequency) and demographic factors (geographic region, education level, and male proportion). …”
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CRO-INSIGHT: Utilization of Implantable Cardioverter Defibrillators in Non-ischemic and Ischemic Cardiomyopathy in a Single Croatian Tertiary Hospital Centre by Mislav Puljevic, Eugen Ciglenecki, Vedran Pasara, Ivan Prepolec, Mia Dubravcic Dosen, Pero Hrabac, Ana-Marija Brekalo, Martina Lovric Bencic, Miroslav Krpan, Richard Matasic, Borka Pezo-Nikolic, Davor Puljevic, Davor Milicic, Vedran Velagic

“…Further research is needed to refine clinical guidelines and optimize patient selection for ICD therapy.…”
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Upgrading Biocrude Derived from Municipal Sludge Hydrothermal Liquefaction Catalyzed by ZSM-5 by Xinyuan ZHU, Yue ZHANG, Botian HAO, Gaocheng CHEN, Donghai XU

“…Future research should focus on optimizing reaction parameters and evaluating long-term catalyst stability to facilitate industrial adoption.…”
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Impact of Preoperative Prism Adaptation Test and Patch Test Measurements on Surgery in Concomitant Horizontal Strabismus: A Prospective Interventional Study by Rahul Singh, Disha Chaudhary, Charu Sagar, Vandana Kohli

“…By providing a more accurate assessment of deviation angles, the PAT reduces the risk of undercorrection and overcorrection compared to conventional preoperative measurements. These findings highlight the importance of incorporating PAT into preoperative evaluations to achieve optimal postoperative alignment and minimise residual deviations. …”
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Elevated mepolizumab levels in patients with severe asthma responsive to 1 year’s mepolizumab treatment by Takayasu Nishimaki, MD, Hitoshi Sasano, MD, PhD, Sonoko Harada, PhD, Tomohito Takeshige, MD, PhD, Yuuki Sandhu, MD, PhD, Yuki Tanabe, MD, Kei Matsuno, MD, PhD, Tetsutaro Nagaoka, MD, PhD, Jun Ito, MD, PhD, Ryo Atsuta, MD, PhD, Mayu Ohuchi, PhD, Shigehiro Yagishita, MD, PhD, Akinobu Hamada, PhD, Kazuhisa Takahashi, MD, PhD, Norihiro Harada, MD, PhD

“…Further research is needed to validate these findings and optimize treatment strategies for patients with severe asthma.…”
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Visible Light Photo-Fenton with Hybrid Activated Carbon and Metal Ferrites for Efficient Treatment of Methyl Orange (Azo Dye) by Malak Hamieh, Nabil Tabaja, Khaled Chawraba, Zeinab Hamie, Mohammad Hammoud, Sami Tlais, Tayssir Hamieh, Joumana Toufaily

“…The leaching of Cr in the solution was very low—0.1 ppm—which is below the detection limit. These findings underscore the potential of the synthesized FeCr-SBA-15/AC hybrid as a cost-effective, environmentally friendly, and highly efficient photo-Fenton catalyst for treating wastewater contaminated by industrial effluents.…”
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Comparative efficacy of Pirfenidone and Meloxicam on early radiotherapy-induced anal sphincter dysfunction in rats by Dragoș Viorel Scripcariu, Cezar Cătălin Caratașu, Mitică Ciorpac, Teodora Alexa-Stratulat, Andrei Szilagyi, Cristian Răzvan Buga, Bogdan Ionuţ Dobrovăț, Bogdan Ionuţ Dobrovăț, Lucian Eva, Andrei Daniel Timofte, Ludmila Lozneanu, Irina-Draga Căruntu, Radu Iliescu, Bogdan Ionel Tamba

“…Further research is needed to elucidate the underlying molecular mechanisms and optimize antifibrotic and myoprotective interventions for clinical application in cancer survivors.…”
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Leaching risk of sulfadiazine in soil: Regulatory role of low-molecular-weight organic acids associated with root exudates by Fuxiang Zhang, Jiaxuan Hong, Qiang Fu, Hongliang Jia, Yi-Fan Li, Yongzhen Ding, Xiaoyan Wang, Song Cui, Guorui Liu

“…This discrepancy suggests that dynamic factors such as pH buffering and competitive adsorption should be integrated into predictive models to better reflect real-world field conditions. These findings contribute to deeper understanding of pollutant transfer mechanisms within the soil-water system and offer actionable insights for mitigating antibiotic diffusion risks in farmland through optimized organic amendment strategies and pH regulation. …”
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