Evaluation of the effects of thyroid functions on frailty in geriatric patients using the Edmonton, SOF and FRAIL Scales by Galip Can Uyar, Mustafa Kemal Kılıç

“…Multivariate logistic regression analyses were performed to identify significant associations between thyroid parameters and frailty. Results The median age of participants was 73 years, and 68.2% (n = 150) were women. …”
Get full text

Dynamic Perviousness of Thrombi in Acute Ischemic Stroke Predicts Clinical Outcome after Reperfusion Therapy by Gergely Bertalan, Miklos Krepuska, Daniel Toth, Jawid Madjidyar, Patrick Thurner, Tilman Schubert, Zsolt Kulcsar

“…Thrombus perviousness, measured with pre-interventional computed tomography (CT), is a relatively new imaging biomarker with the potential to estimate clinical outcome in AIS and optimize therapy. However, reported findings on the relationship between thrombus perviousness and clinical parameters in AIS are conflicting. …”
Get full text

Glutathione and Ascorbic Acid Accumulation in Mango Pulp Under Enhanced UV-B Based on Transcriptome by Hassam Tahir, Muhammad Sajjad, Minjie Qian, Muhammad Zeeshan Ul Haq, Ashar Tahir, Muhammad Aamir Farooq, Ling Wei, Shaopu Shi, Kaibing Zhou, Quansheng Yao

“…Transcriptomic analysis revealed 18 differentially expressed genes (DEGs) related to the AsA-GSH cycle, including <i>MiGR</i>, <i>MiGGT1</i>, <i>MiGGT2</i>, <i>MiGPX1</i>, <i>MiGPX2</i>, <i>MiGST1</i>, <i>MiGST2</i>, <i>MiGST3</i>, <i>MiG6PDH1</i>, <i>MiG6PDH2</i>, <i>MiGalLDH</i>, <i>MiAPX1</i>, <i>MiAPX2</i>, <i>MiAAO1</i>, <i>MiAAO2</i>, <i>MiAAO3</i>, <i>MiAAO4</i>, and <i>MiMDHAR</i>, validated through qRT-PCR. The findings suggest that UV-B stress activates a complex regulatory network in mango pulp to optimize ROS detoxification and conserve antioxidants, offering insights for enhancing the resilience of tropical fruit trees to environmental stressors.…”
Get full text

Impact of Ozone Exposure on the Biochemical Composition of Wheat, Broccoli, Alfalfa, and Radish Seeds During Germination by Ilze Bernate, Tatjana Kince, Vitalijs Radenkovs, Karina Juhnevica-Radenkova, Ingmars Cinkmanis, Juris Bruveris, Martins Sabovics

“…The lack of information has led to the initiation of this study, which aims to assess the impact of ozone treatment duration at a concentration of 50 ppm 1 L min⁻¹, ranging from 1 to 5 h, on the biochemical attributes of broccoli (<i>Brassica oleracea</i>), radish (<i>Raphanus sativus</i>), alfalfa (<i>Medicago sativa</i>) seeds, and sprouts, as well as wheat (<i>Triticum aestivum</i>) grains and sprouts. By optimizing O₃ exposure parameters, including duration, this approach has the potential to serve as a valuable tool for enhancing the microbiological and nutritional quality of seeds and cereals. …”
Get full text

Pitfalls in the diagnosis of apparent homozygous mutations: two cases of IL10RA deficiency inflammatory bowel disease and a literature review by Xiu Shi, Ziqing Ye, Lai Qian, Wenhui Hu, Ye Yang, Chunmeng He, Zhiheng Huang, Bingbing Wu, Ying Huang

“…Both patients were followed up, and descriptive analyses were performed to characterise their clinical phenotypes, biochemical parameters, endoscopic findings, and intestinal histopathology. …”
Get full text

The effect of sports specific warm-up on lower and upper extremity visual response time in female athletes by Ramazan Göğebakan, Dede Baştürk, Abdullah Arguz, Yasemin Bayraktar, Nurtekin Erkmen, Selver Say

“…A significant difference was determined in the comparison of lower extremity visual response times of volleyball and football players before warm-up (t = 3.307, p = 0.004) and after warm-up (U = 20.000, p = 0.008). Conclusions. The findings highlight the importance of sport-specific warm-up protocols in preparing athletes for optimal performance. …”
Get full text

DFT analysis of the [3 + 2] heterocyclization reaction of ((1,2,4-triazole(1,3,4-oxadiazole)-3(2)-yl)methyl)thiopyrimidines by Yu. V. Karpenko

“…The application of solvent models (PCM) allowed for more realistic simulation of reaction conditions. The study’s findings provide a deeper understanding of chemical transformations in heterocyclic systems and can be utilized to optimize synthetic methods in medicine, agrochemistry, and materials science. …”
Get full text

Risk Factors of Aseptic Loosening After Total Hip Arthroplasty With Collum Femoris Preserving Stem: A Long‐Term Follow‐Up Study by Yongbo Ma, Yansong Liu, Zeming Liu, Jiangqi Chang, Mengnan Li, Tao Wu

“…Conversely, higher BMD, improved cortical index, and favorable CFR were protective against loosening. These findings underscore the need for careful preoperative assessment and precise intraoperative positioning to optimize long‐term implant stability.…”
Get full text

Bromocriptine for Idiopathic Intracranial Hypertension: A Retrospective Multicenter Cohort Study by Morsy MM, Azzam AY, Mirdad MT, Abadi AM, Alqahtani SAM, Abukhadijah HJ, Elamin O, Morsy MD, Altschul DJ

“…Future randomized controlled trials are needed to confirm these findings and explore optimal dosing strategies.Keywords: idiopathic intracranial hypertension, pseudotumor cerebri, intracranial pressure, bromocriptine, dopamine…”
Get full text

Development of a novel risk score for diagnosing urinary tract infections: Integrating Sysmex UF-5000i urine fluorescence flow cytometry with urinalysis. by Vo Anh Vinh Trang, Thien Tan Tri Tai Truyen, Minh Thuan Nguyen, Huu Phong Mai, Tri Cuong Phan, Son Hoang Phan, Han My Le Nguyen, Huong-Dung Thi Nguyen, Nguyen Hai Dang Le, Man Nhi Tu, Vo Thanh Vi Huynh, Hoang Tram Anh Nguyen, Dac Bao Han Ho, Ngoc Thuy Uyen Tran, Nguyen Ha Uyen Tran, Bich-Nhat Thi Le, Duc Tuan Doan, Huu Doan Pham, Truong Bao Phan, Phu Phat Pham, Tuan Vinh Nguyen, Phuc Cam Hoang Nguyen

“…Despite being the diagnostic "gold standard," urine culture is limited by slow results and a high rate of false negative findings, leading to treatment delays, higher costs, and overuse of empirical antibiotics. …”
Get full text

Comparación de las variaciones de la composición corporal entre judokas y luchadores hidratados Vs deshidratados (Comparison of body composition variations between hydrated and deh... by Bibiana Calvo Rico, Luis Fernandes Monteiro, Susana Aznar Laín, José Manuel García García

“…Statistical analysis was performed using Kolmogorov-Smirnov and student t tests, which analyze mean differences. The findings and conclusions of the study showed a higher number of dehydrated athletes than those in optimal values of hydration during the pre-competitive period. …”
Get full text

Estimating Spatiotemporal Dynamics of Carbon Storage in <i>Roinia pseudoacacia</i> Plantations in the Caijiachuan Watershed Using Sample Plots and Uncrewed Aerial Vehicle-Borne Las... by Yawei Hu, Ruoxiu Sun, Miaomiao He, Jiongchang Zhao, Yang Li, Shengze Huang, Jianjun Zhang

“…At the sample plot scale, optimal parameters for individual tree segmentation (ITS) based on the canopy height model (CHM) were determined, and segmentation accuracy was validated. …”
Get full text

Cardiometabolic risk assessment by anthropometric and biochemical indices in mexican population by Luz Quirino-Vela, Miguel Mayoral-Chavez, Yobana Pérez-Cervera, Yobana Pérez-Cervera, Osiris Ildefonso-García, Elizabeth Cruz-Altamirano, Monserrat Ruiz-García, Juan Alpuche

“…Sex-based analyses revealed that optimal cut-off values varied, with most indices maintaining a consistent discriminatory capacity across sexes.ConclusionsNon-conventional anthropometric indices, particularly those incorporating metabolic and anthropometric parameters, outperform traditional BMI-based assessments for CMR stratification in Mexican adults. …”
Get full text

Effect of Volumetric Energy Density on the Evolution of the Microstructure and the Degradation Behavior of 3D-Printed Fe-Mn-C Alloys from Water-Atomized Powders by Quang Nguyen Cao, Abdelhakim Cherqaoui, Carlos Henrique Michelin Beraldo, Carlo Paternoster, Simon Gélinas, Carl Blais, Paolo Mengucci, Diego Mantovani

“…Energy-dispersive spectroscopy and Fourier transform infrared spectroscopy analyses identified manganese carbonate as the primary degradation product, with calcium phosphate forming as a secondary product. These findings provide a significant understanding of the relationship between printing parameters, microstructure, and degradation behavior, which are essential for optimizing the performance of Fe-Mn-C alloys in biodegradable material applications.…”
Get full text

A semi-analytical model for flow regime diagnosis in multi-fractured horizontal wells within deep coalbed methane reservoirs by Chang-qing Liu, Zhao-biao Yang, He-qing Chen, Guo-xiao Zhou, Yu-hui Liang, Jun-yu Gu, Yu-qiang Wang, Cun-lei Li, Ben-ju Lu, Shuai-long Feng, Jia-nan Wang

“…These findings offer valuable insights into the gas flow mechanisms of deep coal reservoirs and provide guidance for optimizing multi-fractured horizontal well management strategies.…”
Get full text

Laminectomy and fusion better maintains horizontal gaze than laminoplasty in cervical spondylotic myelopathy by Bradley T. Hammoor, MD, MS, Lara L. Cohen, MD, MPH, Grace X. Xiong, MD, Harry M. Lightsey, MD, Matthew Lindsey, MD, Harold A. Fogel, MD, Daniel G. Tobert, MD, Stuart H. Hershman, MD

“…Postoperatively, LF showed significantly more optimally aligned patients (90.0%) versus LP (57.8%) (p<.01). …”
Get full text

Anisotropic flexible stress sensors based on Loofah/CN/MWCNTs by 刘璐, 贾晓丽, 黄书童, 张景龙, 李守宝, 柯燎亮

“…An orthogonal experiment was designed to determine the optimal parameters for CN concentration, MWCNTs concentration, and dipping times. …”
Get full text

Amphotericin B tissue penetration and pharmacokinetics in healthy and Candida albicans-infected rats: insights from microdialysis and population modeling by Valdeene Vieira Santos, Valdeene Vieira Santos, Laiz Campos Pereira, Laiz Campos Pereira, Jackeline Marley Santos de Araújo, Jackeline Marley Santos de Araújo, Matheus Antônio da Hora Borges, Matheus Antônio da Hora Borges, Carolina Magalhães Brandão, Luisa Oliveira Santos, Luisa Oliveira Santos, Cristiane Flora Villarreal, Francine Johansson Azeredo

“…IntroductionThis study evaluated the relationship between total plasma and free kidney concentrations of amphotericin B (AmB) in healthy and C. albicans-infected Wistar rats using microdialysis and has the potential to significantly impact future research in this field and promote the development of antifungal drugs. The findings of this study, which show that plasma levels are a good predictor for AmB kidney concentrations and can be used to optimize its dosing regimen, underscore the importance of this research.MethodsMicrodialysis probe recovery rates were determined by dialysis and retrodialysis in vitro, as well as by retrodialysis in vivo. …”
Get full text

Development and application of a curcumin-cinnamon essential oil nanoemulsion agent against mycobacteria by Zhihui Lei, Zhihui Lei, Zhihui Lei, Yixuan Ren, Jinyao Wang, Haisu Shi, Hu Lin, Hong Chen, Lijun Bi, Lijun Bi, Yutang Wang, Hongtai Zhang, Hongtai Zhang, Hongtai Zhang

“…In this study, a curcumin-cinnamon essential oil (Cur-CEO) nanoemulsion was developed with optimized preparation parameters, including a 10% CEO volume fraction, 7.5 minutes of ultrasonic treatment, and 350 W ultrasound power, yielding a particle size of 101.14 nm. …”
Get full text

Right ventricular mechanical support as a bridge to lung transplantation: A literature review of current practices by Michaela Orlitová, Bert Demeulenaere, Dieter Van Beersel, Dirk E. Van Raemdonck, Robin Vos, Laurens J. Ceulemans, Steffen Rex, Laurent Godinas, Tom Verbelen, Arne P. Neyrinck

“…Based on our findings, bridging strategies currently lack guidance. …”
Get full text