Cheminformatics approaches to predict the bioactivity and to discover the pharmacophoric traits crucial to block NF-κB by Rahul D. Jawarkar, Suraj N. Mali, Rahul G. Ingle, Sami A. Al-Hussain, Aamal A. Al-Mutairi, Prashant Deshmukh, Magdi E.A. Zaki

“…Thus, the current study found unique pharmacophoric properties that may assist in optimizing lead/hit compounds for anti-IKKβ activity.…”
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Characterization of birefringent Bragg gratings waveguides inscribed with the Femtoprint device by M.Tunon de Lara, L.Amez Droz, K. Chah, P. Lambert, C. Collette, C. Caucheteur

“…This analysis reveals important findings about the actual implemented refractive index modulation. …”
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Mechanical and thermal properties of structural lightweight bamboo fiber-reinforced insulating mortar by Yunyun Tong, Wei Zhang, Mengya Li, Tien Tung Ngo, Qiannan Wang, Wei Zeng, Benyue Li

“…Bamboo fiber-reinforced mortar (BFRM) was evaluated for its microstructural, mechanical, and thermal properties. Key parameters, including fiber content, cement-to-sand (C/S) ratio, and aggregate type and size, were analyzed to optimize the formulation. …”
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Nutritional and bioactive profiles of daylily (Hemerocallis citrina) across flowering stages: A framework for strategic harvest timing by Yuwen Mu, Shenghai Hu, Chunmei Li, Jing Sun, Bei Fan, Fengzhong Wang

“…These findings provide a framework for strategic harvesting: initial flowering maximizes antioxidant properties, full bloom optimizes nutritional content, and final flowering enhances specific flavor compounds, enabling evidence-based decisions to maximize both nutritional value and economic potential.…”
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Synthesis of diatomite/Fe3O4/Teff straw activated carbon composite adsorbent for Cr(VI) removal from wastewater by Sintayehu Shewatatek, Girma Gonfa, Sintayehu Mekuria, Belete Tessema, Gulmira Kezembayeva, Kalyan Sundar Ghosh, Muhammad Mushtaq, Mohammad Hadi Diyanatizadeh, Kaan Isinkaralar, Ahmad Hosseini-Bandegharaei

“…Response surface methodology (RSM) with central composite design (CCD) was exploited to optimize adsorption parameters, including pH, adsorbent dose, initial Cr(VI) concentration, and adsorption time. …”
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Isokinetic Knee Strength as a Predictor of Performance in Elite Ski Mountaineering Sprint Athletes by Burak Kural, Esin Çağla Çağlar, Mine Akkuş Uçar, Uğur Özer, Burcu Yentürk, Hüseyin Çayır, Nuri Muhammet Çelik, Erkan Çimen, Gökhan Arıkan, Levent Ceylan

“…Moreover, identifying and addressing bilateral strength asymmetries may support injury prevention strategies in elite ski mountaineering athletes. These findings provide scientific support for designing training programs targeting explosive hamstring strength, bilateral symmetry, and injury risk reduction, essential for optimizing performance in the 2026 Winter Olympics sprint discipline.…”
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A Difference Wavelet Feature Index for Estimating Aerial N Uptake of Winter Wheat from In Situ Hyperspectral Remote Sensing by Bin-Bin Guo, Wen-Hui Wang, Chao Ma, Jun Zhang, Fei Yin, Wei Feng

“…The findings revealed that CWT exhibited the highest efficacy among all the spectral transform methods, followed by FDR, with <italic>R</italic>² values of 0.777 for WF(4,770) and 0.764 for FDR₇₄₈. …”
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Effects of off-line auricular transcutaneous vagus nerve stimulation (taVNS) on a short-term memory task: a pilot study by Francesco Fisicaro, Francesco Fisicaro, Klizia Cortese, Rita Bella, Manuela Pennisi, Giuseppe Lanza, Giuseppe Lanza, Kaoru Yuasa, Yoshikazu Ugawa, Yasuo Terao

“…Although further studies are needed to better clarify the optimal stimulation parameters, findings from this study could support the use of taVNS as a safe neuromodulation technique to improve cognitive function.…”
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Association of Prenatal Maternal Fever and Neonatal Umbilical Artery Blood-Gas Analysis: Evidence from a Tertiary Center at China by Lijie Lu, Xiuhong Wang, Yunsheng Liao, Lizhen Hu, Tingsong Weng

“…Understanding the influence of prenatal fever on delivery outcomes is crucial for optimizing maternal and neonatal health.…”
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Cascaded lattice Boltzmann simulation of Newtonian and non-Newtonian mixture nanofluids with variable thermophysical properties in a cavity with vertical heat radiator by Md. Mamun Molla, Amzad Hossain, Md. Mahadul Islam

“…For the Bingham fluid, the rate of heat transfer increases 7% from Ra=105 to Ra=106 while ϕ=2% and Bn=0.3. The findings can be applied to optimize automotive radiator systems, which are crucial for maintaining engine temperature.…”
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Foliar Application of Melatonin Improves Photosynthesis and Secondary Metabolism in <i>Chenopodium quinoa</i> Willd. Seedlings Under High-Temperature Stress by Meiqing Li, Jinyang Li, Deke Xing, Yanyou Wu

“…Obvious reductions in gas exchange parameters and metabolites including flavonoid, anthocyanin, and PPO were observed both in the BQ cultivar and the WQ cultivar. …”
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Nitrogen management strategies for boosting growth and yield in Indian mustard (Brassica juncea) by SHITAL KUMAR, RAMANJIT KAUR, TEEKAM SINGH, ANCHAL DASS, R N SAHOO, RAJEEV RANJAN, SUNIL KUMAR

“…This treatment also recorded the highest yield attributes, including the number of siliquae/plant (541.3), seeds/siliqua (13.9), and seed yield (2742 kg/ha), underscoring the efficiency of drone-mediated nitrogen application. These findings highlight the potential of optimized nitrogen management and drone technology in enhancing oilseed production while promoting environmentally sustainable agriculture. …”
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In Vitro Fertilization and Dichorionic-Diamniotic Twin Pregnancies in Nulliparous Women: A Retrospective Cohort Study Comparing Pregnancy Outcomes Between Advanced and Younger Mate... by He MP, Jian WQ, Yuan CL, He SM, He MR, Yan J, Huang JC, Zhao KS

“…Targeted prenatal surveillance for twin growth trajectories and intraoperative hemorrhage management may optimize outcomes in AMA populations. These findings support tailored clinical protocols for this high-risk demographic.Keywords: in vitro fertilization (IVF), dichorionic-diamniotic twin pregnancy (DCDA), advanced maternal age, nulliparous women…”
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A biomechanical investigation of three fixation methods for unilateral denis type II sacral fractures using finite element analysis by Peishuai Zhao, Renjie Li, Jiaqiang Chen, Yongsheng Wang, Jianzhong Guan, Min Wu

“…Notably, BS2AI-ISS achieves this stability without compromising lumbar motion and irrespective of sacral morphologic variations. These findings suggest that BS2AI-ISS may serve as an effective alternative for managing unilateral Denis type II sacral fractures.…”
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A decade-long analysis of 98 chronic myeloid leukemia patients: Laboratory data and clinical progress at a single center by Nabihah Mohd Shakri, Razan Hayati Zulkeflee, Mohd Nazri Hassan, Sinari Salleh, Nur Aini Shakirah Ahmad Shuyuti, Marini Ramli, Azlan Husin, Abu Dzarr Abdullah

“…The e13a2 transcript was linked to higher tumor burden and a higher rate of blastic transformation, suggesting potential prognostic significance. These findings underscore the importance of baseline molecular profiling for optimizing disease management.…”
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Innovative use of indigenous dadih probiotics to enhance feed intake, digestibility, growth performance, and health in heat-stressed Sapera goats by Nurzainah Ginting, Edhy Mirwandhono, Nurjama’yah Br. Ketaren, Yuan-Yu Lin

“…Supplementation with 4 cc dadih optimized performance without disrupting hematological homeostasis, while 8 cc effectively suppressed gut pathogens. …”
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Muscone Ameliorates High-Altitude Hypoxia Gastrointestinal Stress via Modulation of Lactobacillus Murinus and Mitochondrial Metabolism by Zeng J, Yin X, Pang Y, Zhang J, Xie C, Chen S, Zhang L, Li X, Pan Y, An J

“…Transcriptomic analysis and RT-qPCR findings suggest that these effects may be linked to the mitochondrial metabolic pathway.Conclusion: Muscone may alleviate acute high-altitude gastrointestinal stress by enhancing the abundance of Lactobacillus murinus within the intestinal tract. …”
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Reduction of Enteric Pathogens in Bottled Water Using Residual Ozone by William Ryan Schwaner, Sanjay Kumar, Harshavardhan Thippareddi

“…While residual ozone effectively achieves microbial safety benchmarks, elevated TDS and nonneutral pH significantly impair efficacy. These findings underscore the necessity of monitoring water quality parameters to optimize ozone disinfection in bottled water facilities, ensuring consistent compliance with food safety standards.…”
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Laboratory Leaching Tests to Investigate Mobilisation and Recovery of Metals from Geothermal Reservoirs by Máté Osvald, Andrew D. Kilpatrick, Christopher A. Rochelle, János Szanyi, Tamás Medgyes, Balázs Kóbor

“…In this way, the coproduction of energy and metals would be possible and could be optimized according to market demands in the future. …”
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Effect of idebenone supplementation in a semen extender on boar spermatozoa quality during liquid storage by Rehardus Ricco Pantecostoma, Jatesada Jiwakanon, Saksiri Sirisathien

“…In Experiment 2, 78 nM IDB was selected for its optimal effects and further tested (n = 12) for acrosome integrity (fluorescein isothiocyanate-conjugated peanut agglutinin), capacitation status (chlortetracycline staining), LPO (thiobarbituric acid reactive substances), and kinematic parameters. …”
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