Predicting carotid atherosclerosis in latent autoimmune diabetes in adult patients using machine learning models: a retrospective study by Xiaoqin Chen, Zhitong Li, Xiaoying Fan, Yuanyuan Yan, Shiwei Liu

“…Patients with LADA are at an elevated risk of developing cardiovascular diseases, including carotid atherosclerosis. …”
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Topology-aware pathway analysis of spatial transcriptomics by Siras Hakobyan, Maria Schmidt, Hans Binder, Arsen Arakelyan

“…To support interactive exploration of results, we developed the PSF Spatial Browser, an R Shiny application for visualizing pathway activities, gene expression patterns, and deregulated pathway networks.…”
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A Handheld IoT Vis/NIR Spectroscopic System to Assess the Soluble Solids Content of Wine Grapes by Xu Zhang, Ziquan Qin, Ruijie Zhao, Zhuojun Xie, Xuebing Bai

“…This article integrated the AS7265X sensor to develop a low-cost handheld IoT multispectral detection device, which can collect 18 variables in the wavelength range of 410–940 nm. …”
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Identification of Biomarkers Co-Associated with Lactylation and Acetylation in Systemic Lupus Erythematosus by Zhanyan Gao, Yang Feng, Chenghui Zheng, Fei Li, Zhan Sun, Mengmeng Xiang, Junrong Zhu, Mingyu Chu, Jinhua Xu, Jun Liang

“…LASSO regression, support vector machine recursive feature elimination (SVM-RFE), and ROC curve analysis were used to identify hub genes. …”
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Design Optimization of Valve Assemblies in Downhole Rod Pumps to Enhance Operational Reliability in Oil Production by Seitzhan Zaurbekov, Kadyrzhan Zaurbekov, Doszhan Balgayev, Galina Boiko, Ertis Aksholakov, Roman V. Klyuev, Nikita V. Martyushev

“…To mitigate this issue, a novel valve assembly design was developed featuring a flow turbulizer positioned beneath the valve seat. …”
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Two-stage strategic optimal planning of distributed generators and energy storage systems considering demand response program and network reconfiguration by Saleh Ba-swaimi, Renuga Verayiah, Vigna K. Ramachandaramurthy, Ahmad K. ALAhmad, Sanjeevikumar Padmanaban

“…Moreover, the established model, featuring a wind-DG/PV-DG/BESS/DRP/NR configuration, achieves significant improvements in all objective functions, including a 31.14% reduction in total system cost, a 61.67% decrease in power loss, and a 58.11% improvement in voltage deviation, compared to the base case.…”
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Interpretable machine learning-guided single-cell mapping deciphers multi-lineage pancreatic dysregulation in type 2 diabetes by Xueqin Xie, Changchun Wu, Yuhe Yang, Wei Su, Fuying Dao, Jian Huang, Zheng Shi, Hao Lyu, Hao Lin

“…Novel tools included PanSubPred (two-stage feature selection/XGBoost classifier) for multi-lineage annotation and PSC-Stat (XGBoost/Gini optimization) for stellate cell activation analysis. …”
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RUBIES: JWST/NIRSpec Confirmation of an Infrared-luminous, Broad-line Little Red Dot with an Ionized Outflow by Bingjie Wang, Anna de Graaff, Rebecca L. Davies, Jenny E. Greene, Joel Leja, Gabriel B. Brammer, Andy D. Goulding, Tim B. Miller, Katherine A. Suess, Andrea Weibel, Christina C. Williams, Rachel Bezanson, Leindert A. Boogaard, Nikko J. Cleri, Michaela Hirschmann, Harley Katz, Ivo Labbé, Michael V. Maseda, Jorryt Matthee, Ian McConachie, Rohan P. Naidu, Pascal A. Oesch, Hans-Walter Rix, David J. Setton, Katherine E. Whitaker

“…Additionally, we identify a narrow blueshifted He i λ 1.083 μ m absorption feature in NIRSpec/G395M spectra, signaling an ionized outflow with kinetic energy up to ∼1% the luminosity of the AGN. …”
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Identity in turmoil: Investigating the morally injurious dimensions of minority stress by Andrew A. Nicholson, Sandhya Narikuzhy, Jakub Wolf, Mina Pichtikova, Magdalena Siegel, James Mirabelli, Taylor Hatchard, Niki Hosseini-Kamkar, Ella Bawagan, Sophia L. Roth, Christina Mutschler, Ruth A. Lanius, Fardous Hosseiny, Kristen Eckstrand, Brigitte Lueger-Schuster

“…Background: Sexual and gender minorities (SGMs) are at an increased risk for developing mental health disorders due to their socially stigmatized identities. …”
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Regional Brain Aging Disparity Index: Region-Specific Brain Aging State Index for Neurodegenerative Diseases and Chronic Disease Specificity by Yutong Wu, Shen Sun, Chen Zhang, Xiangge Ma, Xinyu Zhu, Yanxue Li, Lan Lin, Zhenrong Fu

“…To address this, we innovatively developed a computational framework featuring efficient Shapley value approximation through a novel multi-stage computational strategy that significantly reduces complexity, thereby enabling an interpretable analysis of deep learning models. …”
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Enhancing the strength and toughness of WTaTiVN+Taμm heterogeneous alloys via nano Ti–V–N precipitation phase adjustment by Yifei Hu, Ang Xu, Jilong Liu, Ruoqi Wang, Jinping Suo

“…This alloy featured dispersed nano Ti–V–N precipitates that formed coherent interfaces, which enhanced strength and toughness through heterogeneous structures and dispersed nanoprecipitates. …”
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International Alliance of Urolithiasis (IAU) consensus on miniaturized percutaneous nephrolithotomy by Guo-Hua Zeng, Wen Zhong, Giorgio Mazzon, Wei Zhu, Sven Lahme, Sanjay Khadgi, Janak Desai, Madhu Agrawal, David Schulsinger, Mantu Gupta, Emanuele Montanari, Juan Manuel Lopez Martinez, Shabir Almousawi, Vincent Emanuel F. Malonzo, Seshadri Sriprasad, Chu Ann Chai, Vimoshan Arumuham, Stefania Ferretti, Wissam Kamal, Ke-Wei Xu, Fan Cheng, Xiao-Feng Gao, Ji-Wen Cheng, Bhaskar Somani, Mordechai Duvdevani, Kah Ann Git, Christian Seitz, Norberto Bernardo, Tarek Ahmed Amin Ibrahim, Albert Aquino, Takahiro Yasui, Cristian Fiori, Thomas Knoll, Athanasios Papatsoris, Nariman Gadzhiev, Ulanbek Zhanbyrbekuly, Oriol Angerri, Hugo Lopez Ramos, Iliya Saltirov, Mohamad Moussa, Guido Giusti, Fabio Vicentini, Edgar Beltran Suarez, Margaret Pearle, Glenn M. Preminger, Qing-Hui Wu, Otas Durutovic, Khurshid Ghani, Marcus Maroccolo, Marianne Brehmer, Palle J. Osther, Marek Zawadzki, Azimdjon Tursunkulov, Monolov Nurbek Kytaibekovich, Abdusamad Abdukakhorovich Abuvohidov, Cesar Antonio Recalde Lara, Zamari Noori, Stefano Paolo Zanetti, Sunil Shrestha, Jean de la Rosette, John Denstedt, Zhang-Qun Ye, Kemal Sarica, Simon Choong

“…Abstract Over the past three decades, there has been increasing interest in miniaturized percutaneous nephrolithotomy (mPCNL) techniques featuring smaller tracts as they offer potential solutions to mitigate complications associated with standard PCNL (sPCNL). …”
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Integration of single-cell RNA and bulk RNA sequencing revealed malignant ductal cell heterogeneity and prognosis signatures in pancreatic cancer by Haiyang Du, Haiyang Du, Gao Si, Jiqing Si, Xuejie Song, Xuejie Song, Fuchun Si, Fuchun Si

“…Non-negative matrix factorization (NMF) identified stage-associated gene modules, which were integrated with TCGA bulk-RNA data and machine-learning feature selection to pinpoint candidate prognostic genes. …”
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The role of T-helper and T regulatory cells in driving neutrophilic and eosinophilic inflammation in bronchiectasis by Evangelia Fouka, Evangelia Fouka, Evangelia Fouka, Anders Lindén, Anders Lindén, Anders Lindén, Apostolos Bossios, Apostolos Bossios, Apostolos Bossios

“…Neutrophilic inflammation is a key pathogenic feature, as indicated by enhanced neutrophil-derived proteases and formation of neutrophil extracellular traps (NETs), associated with poor prognosis. …”
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Denervation of rectus capitis posterior minor as neglected factor in Chiari malformation type I revealed by double blinded prospective study by Yunsen He, Qinjiang Huang, Mingbin Bao, Mengjun Zhang, Xiaolin Hou, Ping Liu, Ye Tao, Hongliang Li, Kun Li, Li Liu, Lili Guo, Hao Wang, Zhou Zhang, Bo Wu

“…The disruption of cerebrospinal fluid (CSF) dynamics at the craniocervical junction (CCJ) is a key pathophysiological feature. The rectus capitis posterior minor (RCPmi), innervated by the C1 nerve root’s posterior branch, significantly facilitates CSF flow at the CCJ, correlating closely with occipital headaches. …”
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Improving Malaria diagnosis through interpretable customized CNNs architectures by Md. Faysal Ahamed, Md Nahiduzzaman, Golam Mahmud, Fariya Bintay Shafi, Mohamed Arselene Ayari, Amith Khandakar, M. Abdullah-Al-Wadud, S. M. Riazul Islam

“…This study highlights the importance of utilizing cutting-edge technologies to develop robust and effective diagnostic tools for malaria prevention.…”
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Text-Guided Synthesis in Medical Multimedia Retrieval: A Framework for Enhanced Colonoscopy Image Classification and Segmentation by Ojonugwa Oluwafemi Ejiga Peter, Opeyemi Taiwo Adeniran, Adetokunbo MacGregor John-Otumu, Fahmi Khalifa, Md Mahmudur Rahman

“…Then, five segmentation models (U-Net, Pyramid Scene Parsing Network (PSNet), Feature Pyramid Network (FPN), Link Network (LinkNet), and Multi-scale Attention Network (MANet)) were adopted. …”
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Multidisciplinary Contributions and Research Trends in eHealth Scholarship (2000-2024): Bibliometric Analysis by Lana V Ivanitskaya, Dimitrios Zikos, Elina Erzikova

“…ObjectiveThis study aims to offer a big picture of research developments and multidisciplinary contributions to eHealth that shaped this field up to 2024. …”
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Post-TACE ALBI-Score Trajectory in Intermediate and Advanced Hepatocellular Carcinoma: Prognostic Implications and Influencing Factors Analysis by Li J, Feng T, Cui C, Wang H, Su T, Jin L, Zhao X, Xiao W

“…A CatBoost-based clinical prediction model was developed to identify factors influencing ALBI-score trajectories, with Shapley Additive Explanations (SHAP) values providing feature importance interpretation.Results: Among 501 patients, three ALBI-score trajectories were identified: improve, stable, and decline. …”
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Pembangunan Aplikasi Virtual Reality Tur Perumahan Pada Balimbingan Permai Regency (PT. Karya Propertindo Utama) by Komang Candra Brata, Reinhard Jonathan Silalahi, Adam Hendra Brata

“…Based on these problems, an interactive virtual reality-based tour application for Balimbingan Permai housing was developed. The main feature of the proposed app is to manage and display all types and details of the house unit catalog in Virtual Reality so that it can be used as an alternative solution for prospective buyers who cannot conduct direct site surveys due to limited time and distance issue. …”
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