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421
Immune-evasive beta cells in type 1 diabetes: innovations in genetic engineering, biomaterials, and computational modeling
Published 2025-08-01“…Type 1 diabetes (T1D) is characterized by the autoimmune destruction of pancreatic beta cells, resulting in lifelong insulin therapy that falls short of a true cure. Beta cell replacement therapies hold immense potential to restore natural insulin production, but they face significant hurdles such as immune rejection, limited donor availability, and long-term graft survival. …”
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422
Evaluation of Environmental Effects of Applied Pesticides on Canola (Brassica napus L.), Sugar Beet (Beta vulgaris L.), and Potato (Solanum tuberosum L.) Fields in Ali Abad Katool...
Published 2025-03-01“…This study investigated the environmental effects of pesticides used in canola, sugar beet, and potato fields in Aliabad Katool County (Golestan province), during 2021-2022.Materials and MethodsFor this purpose, 21 canola fields, six potato fields, and five sugar beet fields were randomly selected and information related to pesticide spraying, field area, crop rotation, and crop yield with continuous monitoring, face-to-face interviews, and completed questionnaires was collected from farmers. …”
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423
The geriatric 5Ms, artificial intelligence, and Hannah Arendt’s critique: ethical reflections within contemporary gerontology
Published 2025-06-01“…The regulation of these technologies should prioritize equity, personalized care, and professional autonomy, ensuring that technological innovation reinforces — rather than replaces — patient-centered medical practice.…”
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424
A Multi-Category Defect Detection Model for Rail Fastener Based on Optimized YOLOv8n
Published 2025-06-01“…Currently, object detection-based rail fastener defect detection methods still face challenges such as limited detection categories, insufficient accuracy, and high computational complexity. …”
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425
STUDENTS' PROFICIENCY IN IDENTIFYING PRONOUNS IN ENGLISH SENTENCES: A STUDY OF SMA SWASTA CERDAS BANGSA
Published 2024-12-01“…Pronouns play a vital role in sentence structure by replacing nouns to avoid redundancy, yet their correct usage poses challenges for learners. …”
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426
A method for estimating the remaining life of power transformers considering loading, hotspot temperature, and oil assessment
Published 2024-12-01“… Power transformers face significant aging issues, which threatens their reliability and service life. …”
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427
Talent Management Pattern Finding with a Succession Approach Using the Met-asynthesis Method
Published 2025-03-01“…Technology and data-related job positions, such as data scientists and quantitative analysts, are among the most in demand, which means that large banks, for example, will face new competition for talent (Whysall et al, 2019). …”
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428
The Validity of Cryptocurrency Transactions and the Analysis of Associated Disputes
Published 2025-03-01“…Cryptocurrency is one of the modern tools that aims to replace money and is sometimes traded among citizens as a commodity or a means of debt payment. …”
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429
Predicting the spatial demand for public charging stations for EVs using multi-source big data: an example from jinan city, china
Published 2025-02-01“…However, public charging stations (PCS) face with problems such as insufficient quantity and unreasonable distribution. …”
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430
Performance and Formation Mechanism of Trainee Teachers' Teaching Anxiety: Based on Spinoza's Theory of Affection
Published 2024-11-01“…Therefore, the trainee teachers should enrich themselves, especially with the fulfillment of concepts that trainee teachers should face up to the inevitability of anxiety, replacing simple imagination with the knowledge of necessity; analyze the generationof anxiety, substituting fuzzy cognition with clear idea; lock the transformation node of anxiety, transcending the single perspective with multiple thinking; formulate the guiding creed of anxiety, turning the imagination sequenceinto rational order; seek the absolute restraint of anxiety, pursuing the ultimate love of education.…”
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431
Comparison of the patency rates of catheter placement via the right external jugular vein route versus the right brachiocephalic vein route in patients experiencing tunneled-cuffed...
Published 2025-12-01“…There was no statistically significant difference in the patency rates at both 1 and 2 years (p = 0.55, p = 0.71).Conclusion In the face of patients experiencing TCC loss, the practice of replacing dialysis catheters via the right EJV and right BCV routes emerges as a safe and efficacious alternative strategy. …”
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432
Redressing labor factor mismatch in Chinese resource-based cities: Does digital economy matter?
Published 2025-06-01“…Growth and mature cities, particularly regenerative cities, face greater mismatch due to accelerated labor force iteration and resource misallocation. …”
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433
Improving Patient Experience by Understanding Barriers and Incentives to Telehealth Adoption Among Physicians at a Large Academic Medical Center
Published 2025-01-01“…Physicians in PM&R and ophthalmology face additional barriers to acquiring physical exam data, leading them to use telehealth as a supplement to, rather than as a replacement for, core functions of patient care. …”
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434
Study on real-time warning system of blind path for the visually impaired based on improved deep residual shrinkage network
Published 2025-04-01“…Abstract Visually impaired individuals often face various obstacles when navigating blind roads, such as road disconnections, obstructions, and more complex road emergencies, which can leave them in difficult situations. …”
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435
Corrosion measurement of thermally sprayed carbide coatings on stainless steel pipes
Published 2024-10-01“…The petrochemical industries face a formidable challenge from corrosion, which leads to high maintenance costs and lost production. …”
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436
Cas9 endonuclease: a molecular tool for in vitro cloning and CRISPR edit detection
Published 2025-04-01“…Large genetic engineering constructs often face limitations in DNA element addition or replacement due to lack of unique endonuclease recognition sites. …”
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437
A Predictive Maintenance System for Reverse Supply Chain Operations
Published 2022-01-01“…<i>Background:</i> Reverse supply chains of machinery and equipment face significant challenges, and overcoming them is critical for effective customer service and sustainable operation. …”
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438
An algorithm for cardiac disease detection based on the magnetic resonance imaging
Published 2025-02-01“…Abstract In experiments to detect heart disease on cardiac magnetic resonance imaging (MRI) medical images, existing object detection models face several challenges including low accuracy and unreliable detection results. …”
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439
Study on the performance of cement stabilized limestone tailings blending macadam in pavement base
Published 2025-06-01“…Limestone tailings, a significant solid waste generated during cement manufacturing, face challenges of low recycling efficiency and limited engineering application, representing an underutilized resource. …”
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440
Fully convolutional video prediction network for complex scenarios
Published 2024-07-01“…Traditional predictive models, often used in simpler settings, face issues like high latency and computational demands, especially in complex real-world environments. …”
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