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Smoking-Associated Changes in Gene Expression in Coronary Artery Disease Patients Using Matched Samples
Published 2024-12-01“…However, the effects of smoking on gene expression in the blood of CAD subjects in Hungary have not been extensively studied. This study aimed to identify differentially expressed genes (DEGs) associated with smoking in CAD subjects. …”
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Reversible downregulation of HLA class I in adenoid cystic carcinoma
Published 2025-04-01“…Based on results from these studies, we treated freshly resected ACCs with interferon-γ or a stimulator of the interferon genes (STING) agonist in vitro. …”
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The influence of metformin treatment on the circulating proteomeResearch in context
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Combination therapy with expanded natural killer cells and atezolizumab exerts potent antitumor immunity in small cell lung cancer
Published 2025-03-01“…Abstract Despite an initial response to platinum-based chemotherapy, most patients with extensive stage of small cell lung cancer (SCLC) have a poor prognosis due to recurrence. …”
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Discordance in genotypic and phenotypic drug susceptibility results: time to reconsider critical concentration of rifampicin
Published 2025-03-01“…The emergence of multidrug-resistant and extensively drug-resistant TB forms poses a challenge to the TB control programs. …”
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High-grade serous ovarian cancer development and anti-PD-1 resistance is driven by IRE1α activity in neutrophils
Published 2024-12-01“…Here, we report that primary HGSO tumors program neutrophils to inhibit T cell anti-tumor function by activating the endoplasmic reticulum (ER) stress sensor IRE1α. …”
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System of Magnetic-Pulse Unit Parameters Automated Control for Plant Treatment in Gardening
Published 2018-03-01“…A flowchart describing the system operation algorithm and a program code of calculating the required displacement of the actuator rod in a Sublime Text were worked out. …”
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Investigating the effects of closed kinetic chain exercises on joint position sense, functionality, range of motion, and pain in individuals with distal radius fracture: a randomiz...
Published 2025-05-01“…Both groups participated in a six-week rehabilitation program after cast removal. Outcome measures included Visual Analog Scale for activity-related pain (VAS-Activity), active ROM (flexion/extension), Disabilities of the Arm, Shoulder, and Hand (DASH) questionnaire, and joint position sense (JPS). …”
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Damoctocog Alfa Pegol, a PEGylated B-domain Deleted Recombinant Extended Half-life Factor VIII for the Treatment of Hemophilia A: A Product Review
Published 2024-08-01“…Damoctocog alfa pegol was generally well tolerated and none of the patients in any of the clinical trials, including the PROTECT VIII clinical program, HEM-POWR, or ongoing single-center studies, developed FVIII inhibitors. …”
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Severely reduced physical performance is already present at the time of admission for stem cell transplantation
Published 2024-06-01“…The study aims to evaluate the fitness status before allo-HSCT and identify correlations between fitness, quality of life and fatigue, clinical data, and previous exercise sessions.Methods Paediatric patients with cancer ≥4 years old, treated with allo-HSCT, were recruited for the ANIMAL trial ('Effects of a low vs. moderate intense exercise program on immune recovery during paediatric allo-HSCT…”
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Barriers and facilitators to maternal healthcare in East Africa: a systematic review and qualitative synthesis of perspectives from women, their families, healthcare providers, and...
Published 2025-02-01“…Key facilitators identified included improved healthcare understanding and women's self-efficacy at the individual level, family support and positive social influences at the interpersonal level, high-quality services, reliable transportation, compassionate care, and health education at the health facility level, community initiatives, gender equality, and maternity waiting homes at the community level, as well as free maternity services and health extension programs at the policy level. Conclusion The synthesis identified key barriers and facilitators to the maternal healthcare in East African countries, ranging from individual to policy levels. …”
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Prodrug-based combinational nanomedicine remodels lipid metabolism for reinforced ferroptosis and immune activation
Published 2025-05-01“…Ferroptosis is a form of programmed cell death characterized by overwhelmed lipid oxidation, and it has emerged as a promising strategy for cancer therapy. …”
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Teleconsultation for infectious disease management in pediatric intensive care
Published 2025-03-01“…Discussion: This study documented a significant reduction in the use of antibiotics expressed as DOT/100 patient-days, suggesting that multidisciplinary teleconsultations were valuable in PICU patient infection disease management and appropriate use of antimicrobials.This preliminary analysis did not show a statistically significant reduction in the proportion of patients treated with at least one antibiotic in the two periods; the extension of the study period and a larger sample size could better investigate this issue. …”
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Catechin-capped silver-doped titanium dioxide nanoparticle enhanced photocatalytic toxic dye degradation
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BMI Association With Treatment Outcomes in Head and Neck Cancer Patients Receiving Immunotherapy: A Comprehensive Review and Meta‐Analysis
Published 2025-02-01“…Aims To investigate the effect of BMI on the survival outcomes of HNC patients treated with immunotherapy. Methods PubMed, Web of Science, and Google Scholar databases were searched extensively for records published until January 2024. …”
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