Effect of an intensive non-invasive program including spinal decompression on MRI-assessed structural changes in cervical disc herniation by Vincenzo Di Modica, Giuseppe J. Sciarrone

“…The aim of the present case series study is to present the results of an intensive non-invasive treatment program primarily based on non-surgical spinal decompression (NSSD) therapy, evaluated using objective MRI image processing methods. …”
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Human neural stem cells directly programmed from peripheral blood show functional integration into the adult mouse brain by Lea Jessica Berg, Chung Ku Lee, Hideaki Matsumura, Anke Leinhaas, Rachel Konang, Ali H. Shaib, Pedro Royero, Julia Schlee, Chao Sheng, Heinz Beck, Martin Karl Schwarz, Nils Brose, Jeong Seop Rhee, Oliver Brüstle

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Understanding the determinants of treated bed net use in Ethiopia: A machine learning classification approach using PMA Ethiopia 2023 survey data. by Abraham Keffale Mengistu

“…<h4>Introduction</h4>Malaria remains a significant public health challenge in Ethiopia, with over 7.3 million cases and 1,157 deaths reported between January 1 and October 20, 2024. Despite extensive distribution campaigns, 35% of insecticide-treated nets (ITNs) remain underutilized, hindering malaria control efforts. …”
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Case Report: Combination of focal vibration therapy and botulinum toxin injections to treat equinus gait in a child with unilateral spastic cerebral palsy by Christophe Boulay, Christophe Boulay, Christophe Boulay, Jacques-Olivier Coq, Morgan Sangeux, Morgan Sangeux, Guillaume Authier, Guillaume Authier, Alexis Ulian, Alexis Ulian, Maud Pradines, Maud Pradines, Marjolaine Baude, Marjolaine Baude, Béatrice Desnous, Jean-Luc Jouve, Jean-Luc Jouve, Bernard Parratte, Emilie Peltier, Sébastien Pesenti, Jean-Michel Gracies, Jean-Michel Gracies

“…In children with spastic cerebral palsy (CP), FVT has also been suggested to reduce spasticity, increase torque production and improve gait function, but evidence is limited.MethodsWe report the case of a child with unilateral spastic CP (USCP) and equinus gait (GFMCS II level) with (i) ankle dorsiflexor paresis, (ii) ankle plantar flexor overactivity, especially in gastrosoleus complex and peroneus longus, (iii) spastic myopathy, affecting gastrosoleus complex in particular, and (iv) calf pain seemingly related to muscle overactivity. The child was treated with a two-month program of alternating dorsiflexor and plantar flexor focal vibration therapy (FVT) and botulinum neurotoxin A (BoNT-A) injections into plantar flexors, alongside conventional physiotherapy.Results and discussionClinical evaluations during the two-month program showed (i) improved walking speed (ii) decreased ankle dorsiflexor paresis and ankle plantar flexor overactivity, especially spastic co-contraction and spasticity, (iii) improved passive extensibility in plantar flexors, and (iv) reduced pain. …”
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An Integrated Strategy to Treat and Control Acid Mine Drainage from Waste Rock and Underground Workings at the Former Franklin Mine in Nova Scotia, Canada: Field Performance Monito... by Christopher Power

“…Site reclamation was completed in 2010 and involved the following: (1) excavation of the dispersed waste rock (117,000 m²) and backfilling with clean soil; (2) consolidation of the excavated waste rock into a covered, compact waste rock pile (WRP) (25,000 m²); and (3) construction of a passive treatment system for the discharging underground mine water. An extensive field sampling program was conducted between 2011 and 2018 to monitor a range of meteorological, cover material, waste rock, groundwater, and surface water quality parameters. …”
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Effect of Anti-Programmed Cell Death-1 Antibody on Middle Ear Mucosal Immune Response to Intranasal Administration of <i>Haemophilus influenzae</i> Outer Membrane Protein by Kazuhiro Yoshinaga, Takashi Hirano, Shingo Umemoto, Yoshinori Kadowaki, Takayuki Matsunaga, Masashi Suzuki

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Comparing the Effects of Mulligan Straight Leg Raising Exercise and Post-Facilitation Stretching Exercises on Hamstring Flexibility in Physiotherapy Students: A Randomized Controll... by Doaa Amin, Amr Abdel-Aziem, Reham Diab, Sameh Ahmed, Amira Abd-Elmonem, Amira El-Gendy, Marwa Eid, Efrem Kentiba, Mohamed ElMeligie

“…Conclusion ‘Muscle energy technique’ appears to be more effective than Mulligan straight leg raise in improving hamstring flexibility, suggesting its potential as a preferred method in physiotherapy for treating hamstring tightness. Further research is needed to explore the long-term effects of Muscle energy technique and the potential benefits of a maintenance program.…”
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Quantifying Plasmodium falciparum infections clustering within households to inform household-based intervention strategies for malaria control programs: An observational study and... by Gillian Stresman, Charlie Whittaker, Hannah C Slater, Teun Bousema, Jackie Cook

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Optimizing fuel break management for core habitat protection against wildfires in the northern Great Basin by Dung Nguyen, Yu Wei, Erin J. Belval, Jesse D. Young, Christopher D. O'Connor, Christopher J. Dunn, David E. Calkin

“…Here, we develop a mixed integer programming model for managing a network of linear fuel breaks to minimize wildfire impacts on the sagebrush (Artemisia spp.) core habitats in the northern Great Basin. …”
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Pembrolizumab-induced donor duodenum perforation after remote simultaneous pancreas-kidney transplant: a case report and literature review by Kasra Shirini, Cinthia Drachenberg, Raphael P. H. Meier

“…The patient’s BCC had been treated with sonidegib for 6 years, and he had been off of immunosuppression for 8 years. …”
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Multi-omics characterization of oncosis in spinal cord injury by Zhipeng Jiang, Youwei Guo, Zihan Wang, Jinhao Ouyang, Hailong Huang, Haoxuan Huang, Tianqian Shen, Lei Wang, Wen Yin, Xingjun Jiang, Caiping Ren

“…Spinal cord injury (SCI) initiates a cascade of complex secondary damage processes, prominently involving programmed cell death (PCD). Although apoptosis and necroptosis have been extensively characterized, the role of oncosis in SCI remains inadequately understood. …”
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Strategies for the Remediation of Micro- and Nanoplastics from Contaminated Food and Water: Advancements and Challenges by Manikant Tripathi, Pankaj Singh, Sukriti Pathak, Ramaswamy Manimekalai, Diksha Garg, Kavya Dashora

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Opportunities for rhinovirus-targeted RNA therapeutics: A narrative review by Camille Esneau, Nathan E Bryant, Sebastian L Johnston, Nathan W Bartlett

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Computational analysis of zoanthamine alkaloids from Zoanthus sp. as potential DKK1 and GSK-3β inhibitors for osteoporosis therapy via Wnt signaling by Ngoc-Thac Pham, Huong-Giang Le, Bo-Rong Peng, Lo-Yun Chen, Mohamed El-Shazly, Jui-Hsin Su, Mei-Hsien Lee, Kuei-Hung Lai

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Structural probing of off-target G protein-coupled receptor activities within a series of adenosine/adenine congeners. by Silvia Paoletta, Dilip K Tosh, Daniela Salvemini, Kenneth A Jacobson

“…Because of the considerable interest of using AR ligands for treating diseases of the CNS, we used the Psychoactive Drug Screening Program (PDSP) for probing promiscuity of these adenosine/adenine congeners at 41 diverse receptors, channels and a transporter. …”
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Comprehensive dialectical behavior therapy for adolescents in a juvenile correctional treatment center: a pilot evaluation by Johanna B. Folk, Phillip Yang, Anne Thomas, Jayme Lyon, Jaisal Patel, Clara Yoon, Barbara Robles-Ramamurthy, Barbara Robles-Ramamurthy, Barbara Robles-Ramamurthy

“…As part of a facility-designed program evaluation, youth completed a battery of empirically validated assessments of mental health and emotion regulation prior to and following completion of the program.ResultsResults show that comprehensive DBT-A is feasible to implement in a juvenile correctional treatment center and overall, youth improved from pre- to post-treatment in mental health symptoms and emotion regulation, with small to medium effect sizes.ConclusionThese findings build upon a growing literature showing dialectical behavior therapy is a promising intervention for treating emotion dysregulation and mental health conditions and can be successfully implemented in juvenile forensic settings.…”
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Obesity in childhood - literature review and educational recommendations by Aleksandra Kiełczewska, Grzegorz Szcześniak, Anna Kiełczewska

“…State of knowledge Treating childhood obesity requires following a personalized weight loss program, as well as adopting healthy eating habits and lifestyle practices. …”
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Kidney cancer PDOXs reveal patient‐specific pro‐malignant effects of antiangiogenics and its molecular traits by Lidia Moserle, Roser Pons, Mar Martínez‐Lozano, Gabriela A Jiménez‐Valerio, August Vidal, Cristina Suárez, Enrique Trilla, José Jiménez, Inés de Torres, Joan Carles, Jordi Senserrich, Susana Aguilar, Luis Palomero, Alberto Amadori, Oriol Casanovas

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Biological Activities of <i>Mikania glomerata</i> and <i>Mikania laevigata</i>: A Scoping Review and Evidence Gap Mapping by Thaís Pelegrin Garcia, Daniela Gorski, Alexandre de Fátima Cobre, Raul Edison Luna Lazo, Gustavo Bertol, Luana Mota Ferreira, Roberto Pontarolo

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A sustainable approach to helminth eggs concentrations removal in sewage sludge from biological wastewater treatment: A Brazilian case study by Guilherme Sgobbi Zagui, Lisandro Simão, Danielma Silva Maia, Brisa Maria Fregonesi, Karina Aparecida Abreu Tonani, Marília Vasconcellos Agnesini, Cristina Filomena Pereira Rosa Paschoalato, Susana Inés Segura-Muñoz

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