HMOVG: An Interactive Computer Program Based on the Huckel Molecular Orbital Model and Making an Extensive Use of Graphic Facilities by Michel Roch, Jean-Jacques Combremont, Jacques Weber

“… HMOVG (Hückel Molecular Orbital Vector General) is basically a Hückel Molecular Orbital (HMO) program making an extensive use of interactive graphic facilities provided by a calligraphic display system. …”
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Relapsed Chronic Lymphocytic Leukaemia with Concomitant Extensive Chronic Graft versus Host Disease after Allogeneic Haematopoietic Stem Cell Transplantation Successfully Treated w... by Ching Soon Teoh, Ai Sim Goh

“…The relapsed CLL was treated successfully with oral venetoclax accessible via a compassionate drug program. …”
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Cost of the national malaria control program and cost-effectiveness of indoor residual spraying and insecticide-treated bed net interventions in two districts of Madagascar by Voahirana Tantely Annick Andrianantoandro, Martine Audibert, Thomas Kesteman, Léonora Ravolanjarasoa, Milijaona Randrianarivelojosia, Christophe Rogier

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Retrospective cohort study assessing clinical outcomes of patients with extensive-stage small cell lung cancer treated with and without consolidative thoracic radiotherapy at the P... by Geoffrey Liu, Vijithan Sugumar, Frances Shepherd, Andrea Bezjak, Xiang Ye, Penelope A Bradbury, Natasha B Leighl, Andrew Hope, Adrian G Sacher, Rohan Salunkhe, Hadee Lone, Luna Zhan, Alexander Sun, John Cho, Srinivas Raman, Meredith Giuliani, Benjamin Lok

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A decade of antimicrobial resistance trends in Pseudomonas aeruginosa: insights from a tertiary care hospital in Saudi Arabia (2013–2022) by Yahya Shabi, Abdullah Algarni, Ali Al bshabshe, Tarik Alazraqi, Glenn Patriquin, Abdulah OS Bawazeer, Safia Abdullah Mohammed, Sara Habbash, Ali Somily, Abdulah J. Alqahtani, Saeed M. S. Alhamhhum

“…Carbapenem resistance was observed in 40% of isolates; 37.5% were multidrug-resistant (MDR), 5.3% were extensively drug-resistant (XDR), and 3.5% met the criteria for difficult-to-treat resistance (DTR).ConclusionThis study provides an overview of PA resistance pattern trends in Saudi Arabia and emphasizes the importance of establishing an antimicrobial stewardship program.…”
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Extensive cervical lesion and treatment outcomes in women with HIV/HPV co-infection by Rosie Mngqibisa, Huichao Chen, Catherine Godfrey, Motshedisi Sebitloane, Unoda Chakalisa, Sharlaa Badal-Faesen, Gaerolwe Masheto, Frank Taulo, Wadzanai Samaneka, Jennifer Tiu, Cynthia Firnhaber, Timothy Wilkin, the AIDS Clinical Trials Group A5282 Study Team

“…This has implications for cervical cancer programs as these lesions can only be optimally treated with surgical therapies such as loop electroexcision procedures, and the capacity for this procedure should be increased to maximise cervical cancer prevention outcomes.…”
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Addition of thoracic radiotherapy to a PD-L1 inhibitor plus chemotherapy regimen delays brain metastasis onset in extensive-stage small cell lung cancer patients without baseline b... by Baiyang Huang, Senyuan Liu, Kaiyue Wang, Jiarui Zhao, Min Li, Xingpeng Wang, Weiqing Wang, Xiaohan Wang, Jinming Yu, Xue Meng, Guoxin Cai

“…Among these patients, 137 (63.4%) received first-line ICIs combined with chemotherapy (ChT), including 32 patients treated with anti-programmed death 1 antibody (αPD-1) and 105 patients treated with anti-programmed death-ligand 1 antibody (αPD-L1), and 79 patients (36.6%) received first-line ChT alone. …”
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Complete remission of a high-risk, locally advanced cervical cancer with para-aortic lymph node metastases treated with first-line tislelizumab plus bevacizumab combined with chemo... by Juan Lang, Juan Lang, Qianqian Liu, Rong Ji, Miao Qiu, Siben Wang, Qingmeng Liu, Dapeng Li, Ping Chen, Zhongkui Xiong, Zhongkui Xiong

“…Herein, we present a case of a newly diagnosed high-risk, locally advanced cervical cancer patient with PALN metastases and low PD-L1 expression, treated with a combination of tislelizumab, bevacizumab, and a platinum-containing chemotherapy regimen followed by radiotherapy with maintenance therapy, resulting in a notable extension of progression-free survival.…”
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Second-line drug resistance among multidrug-resistant tuberculosis patients in Ethiopia: A laboratory-based surveillance by Getu Diriba, Ayinalem Alemu, Bazezew Yenew, Betselot Zerihun Ayano, Michael Hailu, Bedo Buta, Amanuel Wondimu, Zigba Tefera, Abyot Meaza, Getachew Seid, Muluwork Getahun, Biniyam Dagne, Hilina Mollalign, Yeshiwork Abebaw, Melak Getu, Mengistu Tadesse, Tegegn Belhu, Ephrem Alemu, Minilik Demissie, Ashenafi Erresso, Getachew Aga, Andargachew Kumsa, Taye Letta, Saro Abdella, Shewki Moga, Mesay Hailu Dangisso, Getachew Tollera, Gemechu Tadesse

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Treatment outcomes of extensively drug-resistant tuberculosis in Europe: a retrospective cohort studyResearch in context by Yousra Kherabi, Ole Skouvig Pedersen, Christoph Lange, François Bénézit, Dumitru Chesov, Luigi Ruffo Codecasa, Andrii Dudnyk, Nana Kiria, Olha Konstantynovska, Dhiba Marigot-Outtandy, Traian-Constantin Panciu, Corentin Poignon, Sirje Sasi, Dagmar Schaub, Varvara Solodovnikova, Laima Vasiliauskaitè, Lusine Yeghiazaryan, Gunar Günther, Lorenzo Guglielmetti, Alexandra Aubry, Anca Vasiliu, Andrii Dudnyk, Anne Marie McLaughlin, Christoph Lange, Corentin Poignon, Dagmar Schaub, Daniela Cirillo, Daria Podlekareva, Dhiba Marigot-Outtandy, Dumitru Chesov, Edita Davidavičienė, François Bénézit, Giovanni Fumagalli, Giuliana Troia, Gunar Günther, Ilaria Motta, Jerker Jonsson, Jérôme Robert, Johannes Eimer, Laima Vasiliauskaitè, Liga Kuska, Lorenzo Guglielmetti, Luigi Ruffo Codecasa, Lusine Yeghiazaryan, Marcin Skowroński, Margaret Fitzgibbon, Mathieu Revest, Nana Kiria, Nicolas Veziris, Ole Skouvig Pedersen, Olha Konstantynovska, Onya Opota, Piret Viiklepp, Roxana Coriu, Simone Tunesi, Sirje Sasi, Sten Skogmar, Stephanie Bjerrum, Tamar Togonidze, Traian-Constantin Panciu, Troels Lillebaek, Valérie Pourcher, Varvara Solodovnikova, Vivian Bui Le, Yousra Kherabi

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The management of post-traumatic elbow extension deficit in the subacute phase: A case report series of four patients by Germaine Sim, Jennifer Fleming, Celeste Glasgow

“…All participants received 6 weekly therapy sessions which included a standardized home exercise program. Orthotic1-2 received additional extension orthoses which were remoulded each week according to progress. …”
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Comprehensive analysis of extensive drug-resistant Salmonella Typhi in Gujarat region, India: genomic findings and prospective alternative therapy by Sadanand Dangari Akshay, Heli Upadhyaya, Nitin Shukla, Rohit Bhattacharjee, Sunilkumar Das, Urmi Vyas, Priyank Chavda, Nimesh Patel, Dixsha Jamkhandi, Pritesh Sabara, Neeta Khandelwal, Sumeeta Soni, Kamlesh Upadhyaya, Jayesh Katira, Geeti Maheshwari, Madhvi Joshi, Devarshi Gajjar, Chaitanya Joshi

“…The Gujarat State Biotechnology Mission, Government of Gujarat, India, has funded the “Network Program on Antimicrobial Resistance, Superbugs, and One Health” to track antibiotic resistance patterns in the Gujarat region. …”
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Hereditary Painful Callosities Treated with L5 and S1 Pulsed Radiofrequency, Case Report by Moustafa Moustafa, Kenneth Kuan Boon Keat, Hari Gopal

“…We followed a holistic approach by enrolling him in the pain management program and Left L5 and S1 Pulsed Radiofrequency treatment at left L5 and S1 DRGs. …”
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Urine Periostin Level and Renal Function in Malignancy Patients Treated with High-Dose Cisplatine by Harry Yusuf, Andhika Rachman, M Bonar Marbun, Hamzah Shatri, Putri Aliya Ahadini

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Factors impacting commercial carrot seed germination rates in hot water treated seed lots by Gina A. Greenway, Jeremiah Dung

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Antecedent viral immunization and efficacy of immune checkpoint blockade: an extensive serum antibody profile to predict outcomes in non-small cell lung cancer by Francois-Xavier Danlos, Aurélien Marabelle, Tyler Hulett, Fabrice Barlesi, Benjamin Besse, David Planchard, Nathalie Chaput-Gras, Mihaela Aldea, Filippo G Dall’Olio, Paul-Henry Cournède, Quentin Blampey, Wael Salem Zrafi, Matthieu Roulleaux-Dugage, Gabriel Roman, Charles Naltet, Daniel Gautheret

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Abstract 247: Visual versus Computer Software Assessment of Perfusion in Anterior Circulation Stroke Treated with Mechanical Thrombectomy by Igor Rigler, Tina Gspan, Senta Frol, Janja Pretnar Oblak

“…As this method is simple and easy to use, it can be performed in almost any CT unit, even without a software program for CTP analysis or advanced subspecialized knowledge in neuroradiology.…”
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Thapsigargin triggers a non-apoptotic, caspase-independent programmed cell death in basophilic leukaemia cells by Philip Steiner, Korollus Melek, Ancuela Andosch, Lena Wiesbauer, Anna Madlmayr, Michelle Duggan, Hubert H. Kerschbaum, Susanna Zierler

“…These autosis-like features were also observed in TG-treated murine macrophages and human mast cells, suggesting a conserved mechanism across cell types. …”
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The Age-Dependent Increase of Metabolic Syndrome Requires More Extensive and Aggressive Non-Pharmacological and Pharmacological Interventions: A Cross-Sectional Study in an Italian... by Antonello E. Rigamonti, Sabrina Cicolini, Sofia Tamini, Diana Caroli, Silvano G. Cella, Alessandro Sartorio

“…At least in an Italian context of obese females, the age-dependent worsening of glycaemia and BP exerts a fundamental pathophysiological role in the progressive increase of metabolic syndrome with advancing age, which appears to be not adequately treated in a large part of obese subjects. The results of the present study might be useful for public health decision-makers for programming future more extensive and aggressive non-pharmacological and pharmacological interventions in the obese population.…”
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First‐line serplulimab plus chemotherapy in extensive‐stage small‐cell lung cancer: Updated results and biomarker analysis from the ASTRUM‐005 randomized clinical trial by Ying Cheng, Shuang Zhang, Liang Han, Lin Wu, Jun Chen, Peiyan Zhao, Hongmei Sun, Guilan Wen, Yinghua Ji, Anastasia Zimina, Jianhua Shi, Zhijie Pan, Jinsheng Shi, Xicheng Wang, Yuansong Bai, Tamar Melkadze, Yueyin Pan, Xuhong Min, Maksym Viguro, Xingya Li, Yanqiu Zhao, Junquan Yang, Tamta Makharadze, Ekaterine Arkania, Haoyu Yu, Jing Li, Fang Yang, Xinyi Yang, Chen Ling, Qingyu Wang, Yongqiang Shan, Jun Zhu, the ASTRUM‐005 Study Group

“…Abstract Background The ASTRUM‐005 study previously demonstrated a significant overall survival (OS) benefit with serplulimab (a programmed death 1 inhibitor) plus chemotherapy versus chemotherapy alone in previously untreated extensive‐stage small‐cell lung cancer (ES‐SCLC). …”
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