Targeting copper homeostasis: Akkermansia-derived OMVs co-deliver Atox1 siRNA and elesclomol for cancer therapy by Muhammad Hamza, Shuai Wang, Hao Wu, Jiayi Sun, Yang Du, Chuting Zeng, Yike Liu, Kun Li, Xili Zhu, Huiying Liu, Lin Chen, Motao Zhu

“…Simultaneously, ES facilitated efficient copper influx and mitochondrial transport, leading to Fe–S cluster depletion, increased proteotoxic stress, and robust cuproptosis. …”
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RNF31 induces paclitaxel resistance by sustaining ALYREF cytoplasmic–nuclear shuttling in human triple‐negative breast cancer by Shumei Huang, Dongni Shi, Shuqin Dai, Xingyu Jiang, Rui Wang, Muwen Yang, Boyu Chen, Xuwei Chen, Lingzhi Kong, Lixin He, Pinwei Deng, Xiangfu Chen, Chuyong Lin, Yue Li, Jun Li, Libing Song, Yawei Shi, Weidong Wei

“…In paclitaxel‐sensitive TNBC, ALYREF was trapped in the cytoplasm by paclitaxel, while in paclitaxel‐resistant TNBC, ALYREF was efficiently transported into the nucleus to exert its function, allowing the export of the mRNAs encoding paclitaxel‐resistance‐related factors, including tubulin beta 3 class III (TUBB3), stathmin 1 (STMN1), and microtubule‐associated protein Tau (TAU), ultimately inducing paclitaxel resistance in TNBC. …”
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Proactive Scheduling and Routing of MRP-Based Production with Constrained Resources by Jarosław Wikarek, Paweł Sitek

“…By automating the generation of data from MRP/ERP systems, constructing an optimization model, and exporting the results back to the MRP/ERP structure, this method improves decision-making and competes with expensive Advanced Planning and Scheduling (APS) systems. …”
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Insurance industry and China’s regional economic development by X. Xie

“…The study reveals that life insurance and property insurance are conducive to the steady growth of China’s economy, reduce economic risks, promote the development of investment and exports, and promote economic growth. The development of the insurance industry has realized the collection of funds and supported the development of regional industries, and has improved the efficiency of the use of funds. …”
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Global agricultural trade network characteristics and its influencing factors by Junwen Cao, Qingya Lei

“…Agricultural endowment and governance efficiency play a significant role in a country’s agricultural exports.…”
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A novel energy management strategy for LNG ambient air vaporizer coupled with water-bath heater system by Lemei Ren, Wenling Jiao, Guansan Tian

“…By utilizing these models, the heat transfer capacity of the WH can be adjusted based on the variations in the AAV's heat transfer performance and the flow rate of the exported natural gas (NG). …”
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Logistics business management of provider in Thailand with smart logistics by Natpatsaya Setthachotsombut, Komson Sommanawat, Gritsada Sua-iam

“…The model fits satisfactorily and is therefore appropriate for strategic use in large logistics firms in Thailand engaged in the provision of international logistics services including maritime and air freight, dangerous goods transportation, port services for exports, warehouse renting services, customs clearance, and supply chain management from upstream to downstream. …”
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Good Governance and Seigniorage in a Selected OPEC Countries and Iran by ALI Rashid Shamkhal, Kambiz Paykarjou, beitollah Akbari Moghaddam

“…Methodology This study has employed a panel vector autoregression model to investigate the relationship between good governance and seigniorage among the member countries of the Organization of the Petroleum Exporting Countries (OPEC) during the period of 1995-2020. …”
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Analysis of Crude Oil Market Volatility and Macroeconomic Conditions: Empirical Evidence from Nigeria by Nuhu Musa

“…To hedge against oil price volatility, the paper recommends that the Nigerian government adopt policy measures that would increase energy efficiency and reduce the country's dependency on oil exports through diversification in other related productive sectors such as agriculture and manufacturing.…”
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Effect of Macroeconomic Factors on Economic Growth in Indonesia by Hafidz Zainul Mustofa, Moh. Faizin

“…Policy implications include improving FDI efficiency, maintaining currency stability, controlling inflation, setting appropriate interest rate policies, and diversifying exports to support economic growth.…”
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Understanding the Adoption of Halal Logistics through Critical Success Factors and Stakeholder Objectives by Abid Haleem, Mohd Imran Khan, Shahbaz Khan

“…As a starting point, from the existing literature, we adopt a structural model of CSFs to implement Halal Logistics. After that, this paper identifies and validates these CSFs with the support of extensive literature-based reviews, senior managers of Halal exporting organisations, Halal accrediting bodies, and professionals working in logistics and the cold chain. …”
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The impact of temperature and precipitation on wheat production in Türkiye by Aslıhan Atabek Demirhan, Saide Simin Bayraktar

“…Given its significant contribution to employment, exports and national income, agricultural production-climate change relation is considerably crucial for the Turkish economy. …”
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A Comparison of Segmentation Methods for Semantic OctoMap Generation by Marcin Czajka, Maciej Krupka, Daria Kubacka, Michał Remigiusz Janiszewski, Dominik Belter

“…Instead of computationally demanding 3D segmentation of point clouds, we propose efficient segmentation on RGB images and projection of the corresponding LIDAR measurements on the semantic OctoMap. …”
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Beaufort Gyre Liquid Freshwater Content Change Under Greenhouse Warming From an Eddy‐Resolving Climate Simulation by Xuan Shan, Michael Spall, Shantong Sun, Lixin Wu

“…However, traditional climate models cannot resolve oceanic and atmospheric eddies that are critical to the LFWC variations. …”
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Development of Regional Innovation Potential under the Influence of the Oil and Gas Industry by I. L. Beilin

“…The objective of the study is to assess the formation problems and disclose the innovative potential of the regional oil and gas industry as a set of scientific and technological achievements and investment climate of the oil and gas region in the conditions of transformation of the global energy balance, technological and financial independence, sanctions restrictions on oil and gas exports. The result of the study is the development of an equilibrium cyclic model of the system of priority conditions and optimal results of formation and disclosure of the innovation potential of regional development under the influence of the industrial determinant of the budget-forming oil and gas industry and aimed at maintaining the economic resilience of the region.…”
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HOW DO THE MACROECONOMIC DETERMINANTS UNDERPIN THE CAPITAL MARKET DEVELOPMENT IN NORTH MACEDONIA? by Tatjana SPASESKA, Ilija HRISTOSKI

“…Hence, a developed capital market enables efficient financial resource allocation by channeling domestic savings to those that need capital, which in turn leads to increased investment directed towards innovation and supports sustainable growth. …”

Machine learning-based approach for reduction of energy consumption in hybrid energy storage electric vehicle by T. Paulraj, Yeddula Pedda Obulesu

“…A comprehensive model is developed and tested in Simscape to confirm the real-time applicability of this data-driven control strategy for electric vehicles.…”
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Introduction by Verena Balz

“…When decentralisation and regional governance became issues in Dutch planning, regional design became expected to perform not only in discussion on spatial matters, but in political and organisational realms too. When efficiency became a major aspiration of Dutch spatial planning, the use of regional design in planning decision-making gained an efficiency rationale as well. …”
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Antitumor effects of a novel chromosome region maintenance 1 (CRM1) inhibitor on non-small cell lung cancer cells in vitro and in mouse tumor xenografts. by Shuai Wang, Xiaohong Han, Jianfei Wang, Jiarui Yao, Yuankai Shi

“…This study assessed the therapeutic efficiency of the novel CRM1 inhibitor KPT-185 on non-small cell lung cancer (NSCLC).…”
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Healthcare leadership practice and associated factors among primary healthcare managers in East Gojam Zone, Northwest Ethiopia: a mixed method study by Endalew Minwuye Andargie, Wubshet D. Negash, Abebe Kassa Geto, Asmamaw Atnafu

“…Abstract Background Leadership plays a critical role in the delivery of person centered, safe, efficient, and effective healthcare services globally. …”
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