Circulating fibroblast growth factor 21 is associated with blood pressure in the Chinese population: a community-based study by Juanying Zhen, Shuyun Liu, Lin Liu, Xiaodan Zheng, Guoru Zhao, Jianguo Liang, Aimin Xu, Chao Li, Lijie Ren, Jun Wu, Bernard Man Yung Cheung

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An exposomics analysis of 125 biomarkers of exposure to food contaminants and biomarkers of oxidative stress: a randomized cross-over chrononutrition trial of healthy adults by Hayley Kunde, Elina I. Ioannou, Jasmin Chovatiya, Ravikumar Jagani, Pantelis Charisiadis, Manish Arora, Syam S. Andra, Konstantinos C. Makris

“…Associations between contaminants and oxidative stress were further explored using LASSO regression, followed by additional LME, while adjusting for sociodemographics, body mass index and cortisol. …”
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Dynamic brain-heart-gut coupling during sleep: a continuous physiological signal analysis by Guojing Wang, Guojing Wang, Guojing Wang, Hongyun Liu, Hongyun Liu, Shijing Wu, Shijing Wu, Xiaohua Yu, Xiaohua Yu, Weidong Wang, Weidong Wang

“…BackgroundInvestigating brain-heart-gut coupling during sleep is crucial for understanding the coordinated regulatory mechanisms of multiple systems during sleep. Non-invasive continuous physiological signal acquisition techniques have been widely applied in brain-heart dynamic assessment. …”
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Soybean Yield Estimation Using Improved Deep Learning Models With Integrated Multisource and Multitemporal Remote Sensing Data by Jian Li, Junrui Kang, Ji Qi, Jian Lu, Hongkun Fu, Baoqi Liu, Xinglei Lin, Jiawei Zhao, Hengxu Guan, Jing Chang, Zhihan Liu

“…Accurate soybean yield estimation is critically imperative for modern agricultural systems amid escalating global food security pressures, yet conventional methodologies are constrained for large-scale high-frequency monitoring. …”
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Non-adherence to surgical antibiotic prophylaxis guidelines: findings from a mixed-methods study in a developing country by Noha Ali, Ranim Hamouda, Rana Tarek, Menna Abdelhamid, Abdullah Lashin, Rania Hassan, Rania Gamal, Mourad Elfaham, Aya Attia, Ahmed Abdelaleem, Noha Sakna, Amgad Gamal, Sally Aboelenin, Rahma AbdelHafez, Sara Abdelkader, Ashraf Nabhan

“…We aimed to assess adherence to surgical antibiotic prophylaxis guidelines and to explore the factors contributing to non-adherence. …”
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Safety and efficacy of bridging radiation therapy prior to CD19 CAR T for non-Hodgkin lymphoma: a systematic review and meta-analysis by Mohammad Alhomoud, Rahma Ibrahim, Michelle Demetres, Kai Rejeski, Michael Scordo, Roni Shouval, Tobias Tix, Jeremie Martinet, Michelle Foley, Alexandra Gomez-Arteaga, Tsiporah Shore, Paul Pagnini, Mahmoud Aljurf, Monica L. Guzman, Silvia Formenti, Joachim Yahalom, Koen van Besien, Brandon S. Imber, Zhengming Chen, Samuel Yamshon

“…We identified 18 studies encompassed 538 adult NHL patients who received BRT prior to commercial CART19. Random-effect models were applied to explore meta-analysis outcomes. DLBCL was the most common diagnosis (73%), and axicabtagene ciloleucel was the most utilized product (67%). …”
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The Multifactorial Pathogenesis of Endometriosis: A Narrative Review Integrating Hormonal, Immune, and Microbiome Aspects by Zaure Datkhayeva, Ainur Iskakova, Alla Mireeva, Aida Seitaliyeva, Raikhan Skakova, Gulshat Kulniyazova, Aiman Shayakhmetova, Gaukhar Koshkimbayeva, Chapen Sarmuldayeva, Lazzat Nurseitova, Lyailya Koshenova, Gulzhan Imanbekova, Dina Maxutova, Sandugash Yerkenova, Aigerim Shukirbayeva, Ulzhan Pernebekova, Zaure Dushimova, Akerke Amirkhanova

“…Recent evidence suggests that the gut microbiota significantly influence immune responses, estrogen metabolism, and systemic inflammation, potentially contributing to EM progression. …”
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Vaporized hydrogen peroxide sterilization of powered air-purifying respirators: Efficacy and safety assessment by Yeerzati Tuluhongtayi, Wenjun He, Kun Cai, Weifang Han, Sheng Zhang, Jun Liu, Wenwen Lei, Zongxing Zhang, Jiancheng Qi, Guizhen Wu

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YAP/Nrf2 suppresses ferroptosis to alleviate acute lung injury induced by intestinal ischemia/reperfusion by Lu Tang, Chengjie Yang, Yanhua Peng, Mudi Liu, Na Wei, Xin Fan, Bo Yang, Jing Jia, Ye Chen, Jianguo Feng, Jun Zhou

“…However, whether YAP is involved in regulating II/R-induced ALI remains to be further explored. This study aimed to investigate the regulatory role of YAP in ALI and ferroptosis caused by II/R, and to explore whether YAP exerts anti-ferroptosis and anti-inflammatory effects by promoting nuclear factor erythroid 2-related factor 2 (Nrf2) nuclear entry and upregulating Nrf2 expression. …”
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Significance of the gut tract in the therapeutic mechanisms of polydopamine for acute cerebral infarction: neuro-immune interaction through the gut-brain axis by Feng-Hua Xu, Feng-Hua Xu, Xiao Sun, Jun Zhu, Ling-Yang Kong, Yuan Chang, Ning Li, Wen-Xiang Hui, Cong-Peng Zhang, Yi-Ming Cheng, Yi-Ming Cheng, Wen-Xin Han, Zhi-Min Tian, Yan-Ning Qiao, Dong-feng Chen, Lei Liu, Lei Liu, Da-Yun Feng, Jing Han

“…Additionally, the activation of astrocytes in the hippocampal region and neuronal apoptosis were observed in ACI mice. Importantly, our study is the first to provide evidence demonstrating that PDA effectively suppresses the neuroimmune interactions of the gut-brain axis and significantly improves intestinal epithelial barrier integrity.ConclusionWe hope that our discoveries will serve as a foundation for further explorations of the therapeutic mechanisms of PDA in ACI, particularly in elucidating the protective roles of gut microbiota and intestinal barrier function, as well as in the development of more targeted clinical interventions for ACI.…”
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Mixtures of entomopathogenic nematodes provided successful suppression of Bactrocera tau by stimulated dispersal, aggregation, and invasion by Jingqi Liu, Weiwen Li, Congli Wang, Hua Liang, Zhuannan Chu, Guiping Wang, Linhong Jin, Wenxiu Guo, Yi Yu

“…Laboratory bioassays identified Steinernema carpocapsae (Sc) and Heterorhabditis indica (Hi), that were highly virulent to B. tau larvae, achieving up to 100 % mortality at 25 infective juveniles (IJs) /larva. …”
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Machine Learning for the Photonic Evaluation of Cranial and Extracranial Sites in Healthy Individuals and in Patients with Multiple Sclerosis by Antonio Currà, Riccardo Gasbarrone, Davide Gattabria, Nicola Luigi Bragazzi, Giuseppe Bonifazi, Silvia Serranti, Paolo Missori, Francesco Fattapposta, Carlotta Manfredi, Andrea Maffucci, Luca Puce, Lucio Marinelli, Carlo Trompetto

“…This approach allowed us to explore novel biomarkers of neural and systemic impairment in MS, paving the way for potential clinical applications of SWIR spectroscopy in disease monitoring and management. …”
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Factors explaining failure to suppress viral load in pregnant women living with HIV in Mbandaka, Equateur Province (Democratic Republic of Congo) by Jean Claude Efoloko Likulu, Jules Moti Kangite, Freddy Adu Adikaka, Tonton Manga Bosako, Patrick Bongbanga Mundembe, Guillain Boboko Bikoko, Richard Bikopo Betoko, Monizi Mawunu, Jean-Paul Koto-Te-Nyiwa Ngbolua, Félicien Kandolo Tshimungu, Jean Pierre Moyene Elongi

“…Strengthening adherence counselling, promoting early ART initiation, and enhancing social support systems—particularly through marital or community frameworks—are crucial for reducing MTCT. …”
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Cultural keystone species as a tool for biocultural stewardship. A global review by Giulia Mattalia, Alex McAlvay, Irene Teixidor‐Toneu, Jessica Lukawiecki, Faisal Moola, Zemede Asfaw, Rodrigo Cámara‐Leret, Sandra Díaz, F. Merlin Franco, Benjamin S. Halpern, Casey O'Hara, Delphine Renard, Yadav Uprety, Jeffrey Wall, Noelia Zafra‐Calvo, Victoria Reyes‐García

“…This work examines the current use of the term CKS to reconcile a definition and explore its practical applications for biocultural stewardship. …”
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The Capabilities of Optical and C-Band Radar Satellite Data to Detect and Understand Faba Bean Phenology over a 6-Year Period by Frédéric Baup, Rémy Fieuzal, Clément Battista, Herivanona Ramiakatrarivony, Louis Tournier, Serigne-Fallou Diarra, Serge Riazanoff, Frédéric Frappart

“…Future applications could extend this methodology to other crops and explore alternative radar systems for improved monitoring (such as TerraSAR-X, Cosmos-SkyMed, ALOS-2/PALSAR, NISAR, ROSE-L…).…”
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Acute changes in functional connectivity associated with first osteopathic manual treatment in chronic low back pain spatially overlap with opioid receptor expression by Federica Tomaiuolo, Francesco Cerritelli, Carlo Sestieri, Jordan Keys, Teresa Paolucci, Stefano L. Sensi, Antonio Ferretti, Stefano Delli Pizzi

“…Methods: We combined a data-driven approach with a seed-based connectivity analysis to examine the pattern of whole-brain rs-FC in a cohort of thirty cLBP patients before and after a first acute session of OMT (N = 16) or a sham treatment (N = 14). Correlation analyses were performed to explore the relationship between the resulting rs-FC maps and receptor density/gene expression maps derived from in vivo brain atlases, focusing on the opioid and cannabinoid systems. …”
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RTA 408 attenuates TBHP-Induced apoptosis in nucleus pulposus cells via Nrf2/ARE and NF-κB signaling pathways: in vitro and in vivo evidence for mitigating rats’ intervertebral dis... by Weibin Chen, Defang Li, Lihan Chen, Jichang Fei, Mengxuan Bian, Qingmin Zeng, Zengxin Jiang, Jingping Wu

“…These findings support further clinical exploration of RTA 408 as a novel Nrf2-targeted therapy for IDD.…”
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Effects of physical activity and resilience on emotional and behavioral problems in Chinese adolescent: a chained mediation model by YiJie Shi, Wei Zhao, Mariusz Lipowski

“…While parenting styles and physical activity (PA) independently influence adolescent psychological outcomes, their synergistic effects through psychological resilience remain inadequately explored, particularly regarding cultural nuances in Chinese parenting practices (e.g., dual interpretations of overprotection) and chained mediation pathways (parenting → PA → resilience → EBPs).ObjectiveThis study examined the chained mediating roles of physical activity and psychological resilience in the relationship between multidimensional parenting styles (emotional warmth, rejection, overprotection) and EBPs among Chinese adolescents, testing pathways informed by family systems theory and bioecological frameworks.Participants and settingA sample of 503 adolescents (51.09% male; SD = 1.41) was recruited through three-stage cluster sampling across Zhuhai, Guangdong, China. …”
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DEVELOPING YOUTH RESILIENCE IN CONDITIONS OF SOCIAL INSTABILITY AND WAR by Vira Syniakova, Yuliia Bokhonkova, Mykyta Minin

“…Particularly effective were the modules focused on emo- tional literacy, adaptive coping mechanisms, and community-based support. …”
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Key ultrasound predictors in the prenatal assessment of congenital pulmonary airway malformation: a single-center experience by Isabella Fabietti, Alice Novak, Alice Novak, Laura Valfrè, Chiara Vassallo, Domenico Umberto De Rose, Milena Viggiano, Andrea Conforti, Chiara Iacusso, Marco Bonito, Pietro Bagolan, Pietro Bagolan, Leonardo Caforio

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