‘Nelfinavir sensitizes a clinically relevant chemo-radioresistant cervical cancer in-vitro model by targeting the AKT-USP15/USP11-HPV16 E6/E7 axis by Reshma Reddy, Vagmi Gaiwak, Jayant Sastri Goda, Tanuja Teni

“…Resistance to standard therapies is a major challenge in managing cervical cancer, often leading to systemic relapse. This study aimed to develop an in-vitro model of chemo-radioresistant cervical cancer that mimics clinical conditions and also explore the therapeutic potential of the repurposed drug nelfinavir, an HIV protease inhibitor. …”
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Unveiling the dynamic effects of major depressive disorder and its rTMS interventions through energy landscape analysis by Chun-Wang Su, Chun-Wang Su, Yurui Tang, Nai-Long Tang, Nai-Long Tang, Nian Liu, Nian Liu, Jing-Wen Li, Shun Qi, Hua-Ning Wang, Zi-Gang Huang, Zi-Gang Huang

“…Future studies should further explore the clinical applications of these markers and the comprehensive dynamical effects of rTMS intervention.…”
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Research and application analysis on the pollution control of tail gas emissions from CO2 capture absorber by Shijian Lu, Changjun Shen, Miaomiao Liu, Juanjuan Zhang, Mengxiang Fang, Feng Wang, Qingfang Li, Chao Li, Jian Zhang

“…This paper summarizes the types and current status of pollutant emissions from chemical absorption systems, and explores the effects of flue gas condensation nucleation occurring in different salt solutions, carbon dioxide concentration in the flue gas, lean liquid loading, liquid-to-gas ratio, flue gas inlet temperature of the absorber tower, and temperature of the lean liquid on pollutant emissions from carbon dioxide chemical absorption systems by means of a small test experiment with a flue gas treatment design capacity of 3.6 Nm3/h. …”
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Electric vehicles and renewable energy for sustainable mobility: Insights from bibliometric, topic modeling, and societal impact analyses by Hira Tahir, Hasan Erteza Gelani, Sami El-Ferik, Muhammad Tayyab, Nima Khosravi

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Importance of the actual plant height in modulating the within-community spectrum of plant form and function by Dong He, En-Rong Yan, En-Rong Yan, Li-Ting Zheng, Yan-Jun Song, Xiao-Dong Yang, Wen-Hui You, J. Hans C. Cornelissen

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Disease Activity, Inflammation Markers, and Quality of Life Are Associated with Muscle Strength in Croatian Rheumatoid Arthritis Patients—A National-Based Study by Mislav Radić, Ivan Vlak, Marijana Vučković, Senka Rendulić Slivar, Mira Kadojić, Doris Stamenković, Dubravka Bobek, Josipa Radić, Andrea Gelemanović, Andrej Belančić, Erim Bešić, Tonko Vlak

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Simulation analysis of stress-strain performance for a lightweight X-ray pulsar detection telescope frame structure by Qingyong Zhou, Qingyong Zhou, Zhiqiang Huang, Bin Xu, Yaohu Lei, Jianguo Lei, Hang Zhao, Chaojing Ye, Likuan Zhu

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Aspartate aminotransferase to alanine aminotransferase ratio and short-term prognosis of patients with type 2 diabetes hospitalized for heart failure by Dan Liu, Li Liu, Nan Li, Yiling Zhou, Hongmei Huang, Jidong He, Heling Yao, Xiangyang Chen, Xiaochi Tang, Miye Wang, Ying Qi, Si Wang, Ye Zhu, Haoming Tian, Zhenmei An, Sheyu Li

“…Baseline AST/ALT ratio was calculated. The primary outcomes were all-cause death within 30 days after discharge, composite cardiac events, major acute kidney injury, and major systemic infection. …”
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Accepting the Legitimacy of Difference: Tools to Support the Decolonisation of Human Research Ethics in Western Health Research by Erin J. Rooney, Melsina Makaza, Rhonda L. Wilson

“…Cultural insensitivity, systemic biases, and a lack of representation of First Nations peoples may also worsen these issues. …”
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Bioconversion of Meat and Fish-Based Former Foodstuffs by Black Soldier Fly Larvae: A Sustainable Pathway for Reducing Food Waste, Enhancing Nutrient Recovery, with a Circular Econ... by Antonio Franco, Valentina Pucciarelli, Seyed Ali Hosseini, Eric Schmitt, Fulvia Bovera, Carmen Scieuzo, Patrizia Falabella

“…In this study, five different former foodstuffs containing meat and/or fish were tested to evaluate their suitability for BSFL rearing. …”
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Effects of Vegetation Restoration Type on Abundant and Scarce Soil Microbial Taxa in a Loess Plateau Mining Area by Yanping Miao, Daren Zhou, Hongchao Zhao, Pengfei Li, Shiqi Sun, Hangxian Lai, Qiao Guo, Jianxuan Shang

“…Shrubland vegetation enhanced soil nutrient retention and carbon stabilization, whereas the mixed grass–shrub systems promoted niche partitioning among rare taxa. …”
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Metastasis of Squamous Cell Carcinoma of the Larynx to the Right Adrenal Gland—A Case Report by Eliza Działach, Michał Simlot, Karolina Osowiecka, Elżbieta Nowara, Jarosław Markowski, Mateusz Grajek

“…Diagnostic imaging and histopathological examination were complemented by biochemical evaluations to assess hormonal activity. …”
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A validation study of three early warning scores in early identification of gastric cancer patients with deteriorating condition after gastrectomy by Xinli Shi, Huijuan Jie, Naifa Li, Qiongshan Liu, Yue Wang, Changquan Wu, Wenwen Jiang, Bolin Zhang, Shurong Lai, Honglu Xu

“…The discriminating ability (receiver operating characteristic curves), calibration (goodness-of-fit test) and net benefit (clinical decision curves) of the three EWS (NEWS, SEWS, MEWS) were explored to compare their early warning performance for patients at risk of post-operative deterioration. …”
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Prediction of heart failure risk factors from retinal optical imaging via explainable machine learning by Sona M. Al Younis, Samit Kumar Ghosh, Hina Raja, Feryal A. Alskafi, Siamak Yousefi, Siamak Yousefi, Ahsan H. Khandoker

“…Our analysis revealed that retinal thickness metrics, particularly ISOS-RPE and macular thickness in various regions, were significantly reduced in heart failure patients. …”
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英國、臺灣、馬來西亞戶外冒險教育發展之 比較分析 A Comparative Analysis on Outdoor Adventure Education Development in England, Taiwan, and Malaysia by 李晟瑋 Cheng-Wei Li, 葉優寧 Evelyn Yeap Ewe Lin

“…This cross-cultural study explored the development and interpretation of OAE in academic systems of three countries, namely England, Taiwan, and Malaysia. …”
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Psychological and cultural correlates of illness conception and menopausal symptoms: a cross-sectional and longitudinal comparative study of Mosuo, Yi, and Han women by Limin Gao, Limin Gao, Jinyi Wang, Ying Zhang, Xudong Zhao, Xudong Zhao, Haojie Fu, Haojie Fu

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CAG-targeted brain-permeable therapy tested in biallelic humanized polyQ mouse models by Magdalena Surdyka, Żaneta Kalinowska-Pośka, Anna Niewiadomska-Cimicka, Ewelina Jesion, Agnieszka Fiszer, Elisabeth Singer-Mikosch, Lorraine Fievet, Lukasz Przybyl, Nicholas S. Caron, Michael R. Hayden, Huu Phuc Nguyen, Yvon Trottier, Maciej Figiel

“…In polyglutamine (polyQ) diseases, including Huntington disease (HD) and spinocerebellar ataxia type 3 (SCA3), targeting the mutant CAG tract in mRNA could be a therapeutic strategy for lowering pathogenic protein. We explored the viability of this therapeutic strategy in vivo at the level of the reagent design, toxicity, systemic delivery, brain regions transduction, silencing efficiency, and allele preference. …”
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A patient self-report disability identifier within health service electronic medical records: evaluation of patient, carer and clinician acceptability by Joanne Rowe, Alexandra Devine, Nicole Merrick, Marie Huska, Kristen Morris, Kath Feely, Ahuva Segal, Louise Mogg, Jenni Medland, Rebecca Jamwal, Alison Smith, Maricar Gleich, Jeremiah Munakabayo, Christine Imms

“…Methods The Disability Identifier questions were integrated into Electronic Medical Record systems across the five health services in March 2023, with the evaluation period spanning the first nine months of implementation (1st March–30th November 2023). …”
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The potential therapeutic approaches targeting gut health in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS): a narrative review by Chou-Yi Hsu, Irfan Ahmad, Rana Warid Maya, Mayada Ahmed Abass, Jitendra Gupta, Abhayveer Singh, Kamal Kant Joshi, J. Premkumar, Samir Sahoo, Mohsen Khosravi

“…Results The study found notable changes in the gut microbiota diversity and composition in ME/CFS patients, contributing to systemic inflammation and worsening cognitive and physical impairments. …”
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REGIONAL ADAPTATION TO CLIMATE CHANGE: PLANNING CHALLENGES AND THE APPROACH OF THE SAKHA REPUBLIC (YAKUTIA) by Nikita I. Tananaev, Tuyara N. Gavrilyeva, Nadezhda A. Krasilnikova, Zhanna F. Poselskaya, Irina V. Samsonova, Evgeny S. Kolganov

“…Priority is given to initiatives that yield rapid results at minimal cost—such as establishing monitoring and response systems, involving municipalities and industries through subsidies in climate action efforts, and implementing scientific and educational policies. …”