Efficacy of toripalimab in combination with anlotinib in recurrent undifferentiated pleomorphic sarcoma of the sinonasal region: a case report with biomarker analysis by Fang Wu, Junqiao Feng, Hong Wang, Shan Wang, Xiaoguang Cui, Ying Liu, Linli Yan, Kaihong Ye, Rick F. Thorne, Xu Dong Zhang, Ting La

“…Genotyping and immunohistochemistry revealed that the sarcoma cells were rapidly dividing and enriched in vasculature prior to systemic treatment.ConclusionThese findings suggest that the combination of toripalimab and anlotinib may be an effective treatment option for advanced cases of UPS in the sinonasal region.…”
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Induction of tissue resident memory T cells by measles vaccine vector by Heidy Vera-Peralta, Claude Ruffié, Valérie Najburg, Matthias Brione, Chantal Combredet, Phanramphoei Frantz, Jean-Nicolas Tournier, Frédéric Tangy, Marie Mura

“…Measles live attenuated vaccine (MV) induces strong humoral and cellular systemic memory responses allowing the successful control of measles since decades. …”
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Comparative analysis of Opuntia ficus-indica mucilage and gum arabic as wall materials in anthocyanin-rich raspberry pomace microencapsulation for potential food packaging applicat... by NP Mbonambi, F Seke, OA Fawole

“…The encapsulated powders were evaluated for physicochemical, functional, and antimicrobial properties to determine their suitability for food packaging applications. …”
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<em>Voacanga globosa</em> Spirobisindole Alkaloids Exert Antiviral Activity in HIV Latently Infected Cell Lines by Targeting the NF-κB Cascade: In Vitro and In Silico Investigation... by Ma. Sheila M. de Jesus, Allan Patrick G. Macabeo, John Donnie A. Ramos, Von Novi O. de Leon, Kaori Asamitsu, Takashi Okamoto

“…Alkaloids <b>1</b>–<b>3</b> were explored for their inhibitory activity on TNF-α-induced viral replication in two latently HIV-infected cell lines, OM10.1 and J-Lat. …”
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Interaction effects in microbiota-filter media-pharmaceutical in biofilm-based reactors: a case study of anoxic biofilters by Rui Ma, Han Zhao, Ying Zhao, Lili Jin, Hui Huang, Hongqiang Ren

“…The removal of micropollutants, particularly pharmaceuticals, from wastewater remains a significant challenge due to their persistence and complex degradation mechanisms. Biofilm-based systems offer a promising solution due to their high microbial diversity and metabolic versatility. …”
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Evaluating the impact of deep learning approaches on solar and photovoltaic power forecasting: A systematic review by Oussama Khouili, Mohamed Hanine, Mohamed Louzazni, Miguel Angel López Flores, Eduardo García Villena, Imran Ashraf

“…Accurate solar and photovoltaic (PV) power forecasting is essential for optimizing grid integration, managing energy storage, and maximizing the efficiency of solar power systems. Deep learning (DL) models have shown promise in this area due to their ability to learn complex, non-linear relationships within large datasets. …”
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Once a Triple, Not Always a Triple: The Evolution of Hierarchical Triples That Yield Merged Inner Binaries by Cheyanne Shariat, Smadar Naoz, Kareem El-Badry, Antonio C. Rodriguez, Bradley M. S. Hansen, Isabel Angelo, Alexander P. Stephan

“…Our findings indicate that in 26%–54% of wide double white dwarf (DWD) binaries ( s ≳ 100 au), the more massive white dwarf (WD) is a merger product, implying that these DWD binaries were previously triples. Overall, we estimate that 44% ± 14% of observed wide DWDs originated in triple star systems and thereby have rich dynamical histories. …”
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Plant extracellular vesicles: A promising bionic medicine platform for disease treatment and drug delivery by Jichun Yang, Yuhan Wang, Yunqian Fu, Sitong Wang, Yao Luo, Xin Cui, Chenyu Sun, Jianing Ji, Jiaxi Mo, Yang Wang, Yilin Liu, Xinghong Hu, Xiaohui Chen, Yimin Jia, Yang Luo

“…Then, it revealed the therapeutic implications of PEVs as medicines in some common diseases based on their bioactive molecules inside, such as cancer, inflammation, and metabolic disorders. We especially explored the emerging role of PEVs with low immunogenicity and the power for biological barriers crossing as drug delivery systems, underscoring their potential for further industry and clinical applications. …”
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Effect of ultrasonic treatment on the microstructure, antioxidant activities and metabolites of camellia bee pollen by Yanxiang Bi, Shiye Luo, Jiabao Ni, Song Miao, Zhen Ning, Zhihao Zhang, Sijia Xu, Wenli Tian, Wenjun Peng, Xiaoming Fang

“…Further analysis of the purine and nucleotide metabolism pathway indicated that the antioxidant defense systems within camellia bee pollen were activated by ultrasonic treatment, leading to a significant enhancement in its antioxidant capacity. …”
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Response of astrocytes and their interaction with surrounding brain cells after acute ischemia-reperfusion analyzed by single-cell transcriptome sequencing by YongHong Wu, Lei Xie, Jing Sun, Qing Wang, WangXiao Xia, Qiang Cai, XiaoYun Lu, XingChun Gou

“…We acquired astrocyte subclusters’ transcriptional characteristics involved in diversified functions. To explore what stimulus signals cause astrocyte heterogeneity, we present a blueprint for cellular communication between astrocyte subclusters and other surrounding brain cells 12 h after ischemia-reperfusion, and identified 9 genes which are potential and promising for being therapeutic targets and 6 genes were specific to astrocyte subcluster 2 that tend to resist ischemia-reperfusion injury. …”
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Cellular therapies in rheumatic and musculoskeletal diseases by Pedro Franco-Fuquen, Juana Figueroa-Aguirre, David A. Martínez, Eider F. Moreno-Cortes, Juan E. Garcia-Robledo, Fabio Vargas-Cely, Daniela A. Castro-Martínez, Mustafa Almaini, Januario E. Castro

“…These diseases, which include autoimmune disorders such as multiple sclerosis, rheumatoid arthritis, and systemic lupus erythematosus, are marked by the presence of autoreactive B cells that play a critical role in their pathogenesis. …”
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DNA/BSA Binding Affinity and Cytotoxicity of Dinuclear Palladium(II) Complexes with Amino Acids as Ligands by Stefan Jakovljevic, Petar Canovic, Marko Spasic, Marija Zivkovic, Milan Zaric, Radica Zivkovic Zaric, Andjela Franich, Snezana Rajkovic, Zeljko Todorovic, Nenad Relic, Milos Zivic, Nikola Mirkovic

“…UV-Vis and fluorescence spectroscopy were used to investigate the complexes’ interactions with calf thymus DNA (CT-DNA) and bovine serum albumin. …”
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Ocular manifestations in pediatric tumor suppressor gene mutations: a case series and literature review of RB1, NF1, NF2, VHL, and TSC by Aoxiang Wang, Chanyuan Wang, Wen Li, Jing Qiao, Yulin Luo, Yu Tian

“…Abstract Background This study explores ocular manifestations in children with mutations in key tumor suppressor genes (RB1, NF1, NF2, VHL, TSC1/2), which are linked to common pediatric hereditary cancer syndromes. …”
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Sustainable geothermal yield through effective reinjection: reservoir engineering case study of the Dezhou sandstone geothermal reservoir, North Shandong Plain, China by Tingting Zheng, Gudni Axelsson, Fengxin Kang, Jichu Zhao, Pingping Zhang, Tong Bai, Xunchang Yang, Qundao Zhou, Youchun Luo

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Oral and periodontal assessment at the first trimester of pregnancy: The PERISCOPE longitudinal study by Charlotte Thomas, Inessa Timofeeva, Elyes Bouchoucha, Thibault Canceill, Camille Champion, Marion Groussolles, Catherine Arnaud, Christophe Vayssière, Cathy Nabet, Sara Laurencin‐Dalicieux

“…Interestingly these women were more often primiparous, still active professionally and had had a recent oral examination. …”
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Small Farmers’ Agricultural Practices and Adaptation Strategies to Perceived Soil Changes in the Lagoon of Venice, Italy by Tiziana Floridia, Julia Prakofjewa, Luigi Conte, Giulia Mattalia, Raivo Kalle, Renata Sõukand

“…This empirical research aimed to explore farmers’ agricultural practices, perceptions of soil changes, and how they adapt to them. …”
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Integrating National Oral Health Programme and National Tobacco Control Programme in India: a concept for policy coherence by Mithun Pai, Shweta Yellapurkar, Swapna Sarit, Kalyana C. Pentapati, Badekkila Ramachandra Avinash, Ramya Shenoy

“…At least 8.71 million fatalities were attributed to tobacco use, according to recent estimates from the Global Burden of Disease. …”
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New insights into the environmental photochemistry of common-use antibiotics in ice and in water: A comparison of kinetics and influencing factors by Linke Ge, Siyuan Wang, Crispin Halsall, Xuanyan Li, Dongxiao Bai, Shengkai Cao, Peng Zhang

“…These results are of particular relevance for those regions that experience seasonal ice cover in fresh water and coastal marine systems.…”
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Towards Green and Climate-Resilient Urbanization in Rajshahi City: Urban Growth Meets Climate Action in Northern Bangladesh by Md. Shafiul ALAM, Md. Abdullah AL MAMUN, Md. Ashikur RAHMAN, Rumana SULTANA, Md. SALAUDDIN, Naimur RAHMAN, Mst. Rebeka SULTANA, Mostofa Tarequl AHSAN

“…Many studies illustrate that unplanned and spontaneous urbanization is emerging without sufficient planning, posing grave risks to urban infrastructures, including water systems and biodiversity. This paper explores strategies for attaining green and climate-resilient urbanization in Northern Bangladesh by examining the relationship between urban expansion and climate action in Rajshahi city. …”
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PD-1/PD-L1 inhibitors related adverse events: A bibliometric analysis from 2014 to 2024 by Qingya Song, Zongliang Yu, Wenping Lu, Zhili Zhuo, Lei Chang, Heting Mei, Yongjia Cui, Dongni Zhang

“…Future research directions were also explored. The USA ranked first in publication count and total citations. …”
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