Comprehensive analysis of IRF8-related genes and immune characteristics in lupus nephritis by Zhibin Yu, Chenghui Zheng, Yilun Wang

“…BackgroundThere are currently no reliable diagnostic biomarkers or treatments for lupus nephritis (LN), a complication of systemic lupus erythematosus. Objective: We aimed to explore gene networks and potential biomarkers for LN by analyzing the GSE32591 and GSE113342 datasets from the Gene Expression Omnibus database, focusing on IRF8 and IRF8-related genes.MethodsWe used differential expression analysis, functional enrichment, protein-protein interaction (PPI) network construction, and the CIBERSORT algorithm for immune infiltration assessment. …”
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Cognitive processing of Chinese verbal irony: the role of reverse adjacency relations in reaction time and accuracy by Mian Huang, Zijian Li, Yu Zheng, Caini Yang

“…Additionally, this study suggests un explored factors influencing irony comprehension in terms of a speed-accuracy tradeoff by a moderate positive correlation (r = 0.4, p < 0.001) between RT and accuracy cross all conditions and advances cognitive pragmatics by integrating relational hierarchies into irony theories and offers implications for cross-cultural communication, language pedagogy, and NLP systems.…”
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Neutrophil-Percentage-to-Albumin Ratio as a Predictor of Coronary Artery Ectasia: A Comparative Analysis with Inflammatory Biomarkers by Mehdi Karasu, Şeyda Şahin

“…The neutrophil-percentage-to-albumin ratio (NPAR) has emerged as a novel marker of systemic inflammation and may serve as a useful tool in the evaluation of CAE. …”
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Geographical accessibility of emergency neonatal care services in Ethiopia: analysis using the 2016 Ethiopian Emergency Obstetric and Neonatal Care Survey by Andrew Hayen, Getiye Dejenu Kibret, Daniel Demant

“…Measuring the physical accessibility of health services contributes to understanding the performance of health systems, thereby enabling evidence-based health planning and policies. …”
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Facilitators and barriers to anemia prevention in the urban government childcare program for infants and young children in Peru by Carla Tarazona-Meza, Rosario M. Bartolini, Karina Romero, Rebecca Pradeilles, Cecilia Goya, Emily K. Rousham, Paula L. Griffiths, Hilary M. Creed-Kanashiro

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Approximate Bayesian Computation for a Dual-Failure-Modes Models and Its Application to Failure Times Data by Mustapha Muhammad, Badamasi Abba, Jinsen Xiao

“…Extensive simulation studies were conducted to evaluate the performance of ABC-Gibbs on TMWC. …”
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The role of a structured community health worker network in achieving malaria elimination goals in the Dominican Republic: An impact evaluation amid COVID-19 disruptions. by Nicole Michelén Ströfer, Natalia Tejada Bueno, María Yinet Santos Félix, Jose Luis Cruz Raposo, Justin T Lana, Valérian Turbé, Harriet G Napier, Justin M Cohen

“…The study highlights the impact of COVID-19 disruptions on CHWs' performance and explores the network's ability to bounce back from health systems' shocks. …”
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Carboxylated Mesoporous Carbon Nanoparticles as Bicalutamide Carriers with Improved Biopharmaceutical and Chemo-Photothermal Characteristics by Teodora Popova, Borislav Tzankov, Marta Slavkova, Yordan Yordanov, Denitsa Stefanova, Virginia Tzankova, Diana Tzankova, Ivanka Spassova, Daniela Kovacheva, Christina Voycheva

“…However, its poor water solubility, low oral bioavailability, and nonspecific systemic exposure limit its application. To overcome these obstacles, our study explored the potential of non-carboxylated and carboxylated mesoporous carbon nanoparticles (MCN) as advanced drug carriers for bicalutamide (MCN/B and MCN-COOH/B). …”
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Opportunities for Laboratory Testing to Inform Antimicrobial Use for Bovine Respiratory Disease: Application of Information Quality Value Stream Maps in Commercial Feedlots by Simon J. G. Otto, Colleen M. Pollock, Jo-Anne Relf-Eckstein, Lianne McLeod, Cheryl L. Waldner

“…Our objectives were to (1) explore the implementation of information quality value stream mapping as a continuous improvement tool to inform decisions for bovine respiratory disease (BRD) management and AMS and (2) apply the information quality dimensions to identified Kaizen opportunities for the integration of laboratory data into BRD management systems to assess the appropriateness of BRD treatment plans in western Canadian feedlot production. …”
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A dimensional approach to psychosis: identifying cognition, depression, and thought disorder factors in a clinical sample by Mikkel Schöttner Sieler, Philippe Golay, Sandra Vieira, Luis Alameda, Philippe Conus, Paul Klauser, Raoul Jenni, Jagruti Patel, Thomas A. W. Bolton, Patric Hagmann

“…Abstract Traditional classification systems based on broad nosological categories do not adequately capture the high heterogeneity of mental illness. …”
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Integration of holistic education concepts in higher education to building mental health-friendly campuses: Case study from Indonesia by Minsih Minsih, Megan Lawton, Endah Sudarmilah, Fitri Puji Rahmawati, Imam Mujahid, Anggun Yunita Sari

“…Integrating holistic education into curricula and support systems is crucial for improving academic performance and social engagement. …”
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Natural compounds targeting inflammation and oxidative stress in intestinal ischemia-reperfusion injury: a comprehensive review by Balaji Venkataraman, Aya A. Touny, Shamanth Neralagundi Harihar gowdru, Bhoomendra A. Bhongade, Rajesh B. Patil, Shreesh Ojha, Mauro Pessia, Sandeep B. Subramanya

“…The data were categorized according to phytochemical classes, mechanisms of action, and therapeutic outcomes. …”
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Investigating hydrocarbon potential utilizing isopach maps in the paleo-environment of the external Fars region, Zagros fold-thrust belt by Mina Farzaneh, Zahra Maleki, Mehran Arian, Mohammad Ali Ganjavian, Pooria Kianoush

“…Advanced methodologies— including isopach maps and basin modeling—were employed to examine the spatial distribution of source rocks, reservoir rocks, and cap rocks around the Nezamabad Fault. …”
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Formulation optimization, in vitro and in vivo evaluation of niosomal nanocarriers for enhanced topical delivery of cetirizine by Mohammed F. Aldawsari, El-Sayed Khafagy, Ehssan H. Moglad, Amr Selim Abu Lila

“…Niosomes are surfactant-based nanovesicular systems that have promising applications in both topical and transdermal drug delivery. …”
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Human paradox research and practice by Aysin Pasamehmetoglu

“…<strong>Green Human Resource Management (GHRM) and Sustainability: A Mini Review</strong><strong></strong> Kevser Bahar Meriç Atakan explored core HR functions, such as recruitment, training, performance appraisal, and reward systems, which are being restructured to align with green principles. …”
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Using machine learning models to plan HIV services: Emerging opportunities in design, implementation and evaluation by T Dzinamarira, E Mbunge, I Chingombe, D F Cuadros, E Moyo, I Chitungo, G Murewanhema, B Muchemwa, G Rwibasira, O Mugurungi, G Musuka, H Herrera

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Plant-Based Sunscreen Emulgel: UV Boosting Effect of Bilberry and Green Tea NaDES Extracts by Milica Martinović, Ivana Nešić, Dragica Bojović, Ana Žugić, Slavica Blagojević, Stevan Blagojević, Vanja M. Tadić

“…This study explored the incorporation of these NaDES extracts into various carrier systems: hydrogels, emulsions, and emulgels stabilized with hydroxyethyl cellulose or xanthan gum. …”
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Translational studies on pancreatic cancer and gastric cancer: a methodology in PhD thesis by Mathilde Resell, Gunnar Qvigstad, Timothy C. Wang, Anne S. Quante, África González-Fernández, África González-Fernández, Helge Waldum, Duan Chen, Chun-Mei Zhao

“…Patient and Public Involvement (PPI) was explored to align research priorities with patients’ needs. …”
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The Therapeutic Efficacy and Molecular Mechanisms of <i>Artemisia argyi</i> Essential Oil in Treating Feline Herpesvirus Infection via Nasal Drops by Tian Wan, Jinze Li, Jiayi Liu, Yingxin Chen, Yihao Guo, Xianjie Deng, Xingyao Li, Jiachen Bi, Chongchong Hu, Jianyu Chang, Kai Fan

“…FeHV-1, the causative agent of feline viral rhinotracheitis (FVR), leads to severe respiratory and systemic complications in cats. In this study, 35 cats were divided into blank, FeHV-1 infection, and AAEO treatment groups (high, medium, and low doses). …”
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Genetic regulation and variation of fetal plasma metabolome in the context of sex, paternal breeds and variable fetal weight by Siriluck Ponsuksili, Eduard Murani, Beate Fuchs, Christina E. Galuska, Henry Reyer, Muhammad Arsalan Iqbal, Shuaichen Li, Michael Oster, Klaus Wimmers

“…Additionally, metabolite associations with sex, fetal weight and sire’s breed were explored, revealing significant associations for 354 metabolites. …”
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