Reevaluating Backup Monitor Chamber Tolerances for Stereotactic Body Radiotherapy Treatments using Volumetric-modulated Arc Therapy by Yong Sang, Jun Dang, Jianan Wu, Enzhuo Quan

“…Reducing the tolerance to 1.0% decreased the number of errors, but high-MU arcs still triggered errors. At a 0.5% tolerance, errors persisted in high-MU cases such as multi-target lung cancer. …”
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Efficacy and safety of olanzapine for treatment of patients with bipolar depression: Chinese subpopulation analysis of a double-blind, randomized, placebo-controlled study by Wang G, Cheng Y, Wang J, Wu SH, Xue HB

“…Similar proportions of patients treated with olanzapine (75.0%) and placebo (72.9%) completed the double-blind phase. …”
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Addressing the dynamic nature of reference data: a new nucleotide database for robust metagenomic classification by Jose Manuel Martí, Car Reen Kok, James B. Thissen, Nisha J. Mulakken, Aram Avila-Herrera, Crystal J. Jaing, Jonathan E. Allen, Nicholas A. Be

“…This new resource demonstrably reduces errors and improves the reliability of microbial identification across diverse taxonomic groups. …”
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Rethinking phenylalanine levels in phenylketonuria for optimal neurocognitive development beyond childhood by Beatriz Câmara, Cristina Florindo, Cláudia Bandeira de Lima, Nélia Correia, Inês Fernandes, Manuela Batista, Ana Gaspar, Patrícia Janeiro, Patrícia Janeiro

“…IntroductionPhenylketonuria (PKU) is an inborn error of phenylalanine (Phe) metabolism that disrupts neurotransmitter balance. …”
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Pneumorrhachis with spontaneous pneumomediastinum in pediatric patients: An 11-year retrospective study in Southern Taiwan by Yu-Tang Chang, Chieh-Ni Kao, Yu-Ling Huang, Hung-Hsing Chiang, Jui-Ying Lee, Hsien-Pin Li, Po-Chih Chang, Shah-Hwa Chou, Yu-Wei Liu

“…On multivariable regression analysis, the SPM plus PR group exhibited more predisposing factors than did the SPM group (coefficient: 0.514, standard error: 0.136, p < 0.001). All patients were successfully treated without morbidity and mortality. …”
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Empirical modeling of the percent depth dose for megavoltage photon beams. by Xiao-Jun Li, Yan-Cheng Ye, Yan-Shan Zhang, Jia-Ming Wu

“…The parameter μ can be treated as attenuation coefficient in tail function and decreases when photon energy increased. …”
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Building radiomics models based on ACR TI-RADS combining clinical features for discriminating benign and malignant thyroid nodules by Xingxing Chen, Xingxing Chen, Lili Zhang, Bin Chen, Jiajia Lu

“…The calibration curve demonstrated that the mean absolute error in the training group was just 0.020 and in the test cohort was 0.033. …”
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Effectiveness and safety of direct oral anticoagulants in patients with atrial fibrillation and chronic kidney disease: a systematic review and meta-analysis of clinical trials by E. M. Mezhonov, Z. M. Safiullina, Y. A. Vyalkina, S. V. Shalaev

“…The results showed that in patients with stage C4-C5 chronic kidney disease treated with direct oral anticoagulants, ischemic stroke/systemic embolism was 26% less likely to develop compared with warfarin (HR=0.74, 95% CI 0.57–0 .95, p=0.02). …”
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Validity and reliability of the Manchester Oxford Foot Questionnaire (MOXFQ) in one-year postoperative ankle fracture patients—a validation study by Michael Quan Nguyen, Marjolein Memelink Iversen, Knut Harboe, Ingvild Dalen, Aksel Paulsen

“…The domains had good internal consistency (McDonald’s omega 0.80 to 0.95) and test-retest reliability (ICC 0.80 to 0.92). The standard errors of measurements for the three domains were between 6.5 and 7.5, and 5.5 for the MOXFQ-Index (scale 0 to 100). …”
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Feasibility study of automatic radiotherapy treatment planning for cervical cancer using a large language model by Shuoyang Wei, Ankang Hu, Yongguang Liang, Jingru Yang, Lang Yu, Wenbo Li, Bo Yang, Jie Qiu

“…Abstract Background Radiotherapy treatment planning traditionally involves complex and time-consuming processes, often relying on trial-and-error methods. The emergence of artificial intelligence, particularly Large Language Models (LLMs), surpassing human capabilities and existing algorithms in various domains, presents an opportunity to automate and enhance this optimization process. …”
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Drying kinetics and mathematical modeling of coconut meat slices: Insight into pretreatment and drying synergic effect by Daniel Kwabena Fordjour, Frederick Sarpong, James Owusu-Kwarteng, Evans Frimpong Boateng

“…Drying-kinetics models were validated using determination coefficient (R2) and root mean square error (RMSE). The Asymptotic model satisfactorily suited the samples' drying data goodness fitting based on R2 ≥0.90−0.99 and low RMSE ≤0.01−0.12 compared to other models for both drying methods. …”
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Development of hybrid stacking machine learning for evaluating parameters affecting refrigerated shrimp coated with chitosan-loaded Salvia officinalis nanoemulsions by Mehran Sayadi, Elahe Abedi, Najmeh Oliyaei, Maryam Mousavifard

“…The chemical results showed that the pH of all groups increased during storage, and the pH of the control group reached 11.14 ± 0.13, while it was 8.67±0.91 for the Ch-NEO-3 treated group. Moreover, PV and TBARS values of Ch-NEO-1 (14.51±0.02 meq O2 /kg lipid and 0.59± 0.01 mg MDA/kg) and Ch-NEO-3 (14.32±0.04 and 0.56± 0.01 mg MDA/kg) treated groups were significantly lower than those of control (1.41± 0.09 mg MDA/kg) after 12 days (p < 0.05). …”
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Fabrication of CuSn functionally gradient electrode and its application in EDM for processing micro-groove by Bin Xu, Weitong Liu, Shutian Zhang, Likuan Zhu, Qingyong Zhou, Xiaoyu Wu

“…This mathematical mode was used to predict the cross-sectional profiles of the micro-grooves fabricated by EDM of CuSn-FG electrodes heat-treated at different temperatures. Analyzing the prediction results and the experimental results, we found that the relative error of the mathematical model was less than 5 %, indicating the accuracy of the mathematical model.…”
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Physiologically Based Pharmacokinetic Model of Tyrosine Kinase Inhibitors to Predict Target Site Penetration, with PET‐Guided Verification by Suzanne van derGaag, Tamara Jordens, Maqsood Yaqub, Robbin Grijseels, Daan W. vanValkengoed, Evelien N. deLangen, Ruben van denBroek, Victor L. J. L. Thijssen, Adrianus J. deLangen, Mathilde C. M. Kouwenhoven, Idris Bahce, Bart A. Westerman, N. Harry Hendrikse, Imke H. Bartelink

“…ABSTRACT Osimertinib, a tyrosine kinase inhibitor (TKI), treats non‐small cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) mutations. …”
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Potential Efficacy of Midazolam as Second-Line Treatment for Terminal Dyspnea in Patients with Cancer: Secondary Analysis of a Multicenter Prospective Cohort Study by Satoru Miwa, Masanori Mori, Takashi Yamaguchi, Kozue Suzuki, Yoshinobu Matsuda, Ryo Matsunuma, Hiroaki Watanabe, Tomoo Ikari, Yoshihisa Matsumoto, Kengo Imai, Naosuke Yokomichi, Toshihiro Yamauchi, Soichiro Okamoto, Satoshi Inoue, Akira Inoue, Tatsuya Morita, Eriko Satomi

“…Results: Of the 108 patients enrolled in the main study, 19 exhibited persistent dyspnea despite opioid titration. Four patients were treated with low-dose midazolam, and 15 were treated with further opioid titration. …”
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Neutrophil-lymphocyte ratio: A novel outcome prognosticator following traumatic brain injury: A retrospective analysis by Siddharth Srinivasan, Ajay Hegde, Veeradithya Ballal, Sarah Johnson, Rajesh Nair, Bharat Raju, Yasaswi Kanneganti, Udgam Baxi, Susanth Subramanian, Raghavendra Nayak, Ashwin Pai, Girish Menon

“…Methods: Single-centre, retrospective study on 478 TBI patients treated between January 2019 to January 2022. Patients with moderate to severe traumatic brain injury admitted within 24 h of injury were included. …”
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Clinical validation of using a commercial synthetic-computed tomography solution for brain MRI-only radiotherapy treatment planning by Lamyaa Aljaafari, Richard Speight, David L. Buckley, David Bird, Bashar Al-Qaisieh

“…The OAR mean dose differences were less than 0.3 % for all OARs. 4 of 93 patients (4.3 %) showed gross dosimetric errors of greater than ± 2 %. 3/4 were caused by sCT error. …”
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Sensitive liquid biopsy monitoring correlates with outcome in the prospective international GPOH-DCOG high-risk neuroblastoma RT-qPCR validation study by Lieke M. J. van Zogchel, Boris Decarolis, Esther M. van Wezel, Lily Zappeij‐Kannegieter, Nina U. Gelineau, Roswitha Schumacher‐Kuckelkorn, Thorsten Simon, Frank Berthold, Max M. van Noesel, Marta Fiocco, C. Ellen van der Schoot, Barbara Hero, Janine Stutterheim, Godelieve A. M. Tytgat

“…Any post-induction RT-qPCR positivity correlated with poor EFS and OS, with a HR of 2.10 [1.27-3.49] and 1.76 [1.01-3.08] and 5-years EFS of 26.6% [standard error 5.2%] versus 60.4% [6.7] and OS of 43.8% [5.9] versus 65.7% [6.6] for RT-qPCR-positive patients versus RT-qPCR-negative patients. …”
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Smartphone screen time reduction improves mental health: a randomized controlled trial by Christoph Pieh, Elke Humer, Andreas Hoenigl, Julia Schwab, Doris Mayerhofer, Rachel Dale, Katja Haider

“…Significant group differences (p ≤ .05) were found post-intervention (t1) for depressive symptoms (Mean Difference (MD) = 2.11, Standard Error (SE) = 0.63, 95% Confidence Interval (CI) [0.87, 3.36]), sleep quality (MD = 2.59, SE = 0.97, 95% CI [0.66, 4.51]), well-being (MD = -1.54, SE = 0.68, 95% CI [.-2.89, -0.18]), and stress (MD = 6.91, SE = 3.48, 95% CI [0.01, 13.81]). …”
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Assessing the direct and spillover protective effectiveness of Wolbachia-mediated introgression to combat dengueResearch in context by Jo Yi Chow, Somya Bansal, Borame S.L. Dickens, Pei Ma, Ary Hoffmann, Yoon Ling Cheong, Nazni Wasi Ahmad, Jue Tao Lim

“…SCs were compared to directly/spillover-treated sites to estimate the impact of Wolbachia-introgression on dengue incidence across each site, calendar year and intervention time. …”
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