Patient buy-in to social prescribing through link workers as part of person-centred care: a realist evaluation by Stephanie Tierney, Geoffrey Wong, Debra Westlake, Amadea Turk, Steven Markham, Jordan Gorenberg, Joanne Reeve, Caroline Mitchell, Kerryn Husk, Sabi Redwood, Tony Meacock, Catherine Pope, Beccy Baird, Kamal R Mahtani

“…Setting Patients engaging with link workers in seven different parts of England were involved. Methods As part of data collection, we observed link workers interacting with 35 patients. …”
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Investigating the Causal Relationship of C-Reactive Protein with 32 Complex Somatic and Psychiatric Outcomes: A Large-Scale Cross-Consortium Mendelian Randomization Study. by Bram P Prins, Ali Abbasi, Anson Wong, Ahmad Vaez, Ilja Nolte, Nora Franceschini, Philip E Stuart, Javier Guterriez Achury, Vanisha Mistry, Jonathan P Bradfield, Ana M Valdes, Jose Bras, Aleksey Shatunov, PAGE Consortium, International Stroke Genetics Consortium, Systemic Sclerosis consortium, Treat OA consortium, DIAGRAM Consortium, CARDIoGRAMplusC4D Consortium, ALS consortium, International Parkinson’s Disease Genomics Consortium, Autism Spectrum Disorder Working Group of the Psychiatric Genomics Consortium, CKDGen consortium, GERAD1 Consortium, International Consortium for Blood Pressure, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Inflammation Working Group of the CHARGE Consortium, Chen Lu, Buhm Han, Soumya Raychaudhuri, Steve Bevan, Maureen D Mayes, Lam C Tsoi, Evangelos Evangelou, Rajan P Nair, Struan F A Grant, Constantin Polychronakos, Timothy R D Radstake, David A van Heel, Melanie L Dunstan, Nicholas W Wood, Ammar Al-Chalabi, Abbas Dehghan, Hakon Hakonarson, Hugh S Markus, James T Elder, Jo Knight, Dan E Arking, Timothy D Spector, Bobby P C Koeleman, Cornelia M van Duijn, Javier Martin, Andrew P Morris, Rinse K Weersma, Cisca Wijmenga, Patricia B Munroe, John R B Perry, Jennie G Pouget, Yalda Jamshidi, Harold Snieder, Behrooz Z Alizadeh

“…Yet it is inconclusive whether these associations are causal.<h4>Methods and findings</h4>We performed Mendelian randomization (MR) analyses using two genetic risk scores (GRSs) as instrumental variables (IVs). …”
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Design and analysis of spiral plating solution flow and rotating magnetic field device for electroplated diamond wire saw by Wei HUANG, Yanming HE, Jinbao XU, Zhenya SONG, Xiang HUANG, Yumeng SUN, Ximeng YU

“…The basic parameters of the combined device are: the magnet size is φ20 mm × 30 mm, the inner wall diameter × length of the glass tube is φ56 mm × 850 mm, the baseline travel speed is less than or equal to 20 m/min, the bottom diameter of the spiral blade is 5 mm, the blade thickness is 2 mm, and the concentration of diamond abrasive is 1.55 g/L. …”
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Role and mechanism of action of nuclear receptor coactivator 4 in the development of acquired resis-tance to targeted inhibitors in pancreatic cancer with KRAS G12C mutation by CHANG Hao, WANG Ya'nan, LIU Shihai, WANG Jing

“…Objective To investigate the role and mechanism of action of nuclear receptor coactivator 4 (NCOA4) in acquired resistance to targeted inhibitors in pancreatic cancer with KRAS G12C mutation. Methods Human pancreatic cancer cell lines CFPAC-1, PANC-1, and MIA-PaCa-2 were cultured in vitro. …”
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Development and validation of a risk prediction model for premenopausal breast cancer in 19 cohorts by Kristen D. Brantley, Michael E. Jones, Rulla M. Tamimi, Bernard A. Rosner, Peter Kraft, Hazel B. Nichols, Katie M. O’Brien, Hans-Olov Adami, Amaia Aizpurua, Amy Berrington de González, William J. Blot, Tonje Braaten, Yu Chen, Jessica Clague DeHart, Laure Dossus, Sjoerd Elias, Renée T. Fortner, Montserrat Garcia-Closas, Inger T. Gram, Niclas Håkansson, Susan E. Hankinson, Cari M. Kitahara, Woon-Puay Koh, Martha S. Linet, Robert J. MacInnis, Giovanna Masala, Lene Mellemkjær, Roger L. Milne, David C. Muller, Hannah Lui Park, Kathryn J. Ruddy, Sven Sandin, Xiao-Ou Shu, Sandar Tin Tin, Thérèse Truong, Celine M. Vachon, Lars J. Vatten, Kala Visvanathan, Elisabete Weiderpass, Walter Willett, Alicja Wolk, Jian-Min Yuan, Wei Zheng, Dale P. Sandler, Minouk J. Schoemaker, Anthony J. Swerdlow, A. Heather Eliassen

“…Abstract Background Incidence of premenopausal breast cancer (BC) has risen in recent years, though most existing BC prediction models are not generalizable to young women due to underrepresentation of this age group in model development. Methods Using questionnaire-based data from 19 prospective studies harmonized within the Premenopausal Breast Cancer Collaborative Group (PBCCG), representing 783,830 women, we developed a premenopausal BC risk prediction model. …”
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Gender Influence on Bimekizumab Response in Patients with Psoriasis: Results of a Real-World Multicenter Retrospective Study—IL PSO (Italian Landscape PSOriasis) by Helena Gioacchini, Agnese Rossi, Maria Esposito, Emanuele Vagnozzi, Maria Concetta Fargnoli, Paolo Gisondi, Francesco Bellinato, Chiara Assorgi, Pina Brianti, Santo Raffaele Mercuri, Martina Burlando, Emanuele Cozzani, Giovanna Brunasso, Stefano Caccavale, Anna Balato, Giacomo Caldarola, Clara De Simone, Elena Campione, Alessandro Giunta, Francesco Tonon, Marina Venturini, Carlo Giovanni Carrera, Angelo Valerio Marzano, Andrea Carugno, Paolo Sena, Antonio Costanzo, Alessandra Narcisi, Francesco Cusano, Paolo Dapavo, Pietro Quaglino, Annunziata Dattola, Antonio Giovanni Richetta, Francesca Gaiani, Piergiorgio Malagoli, Matteo Megna, Luca Potestio, Edoardo Mortato, Francesco Loconsole, Francesca Romano, Andrea Faragalli, Rosaria Gesuita, Tommaso Bianchelli, Federico Diotallevi, Diego Orsini, Anna Campanati

“…Notably, no studies have specifically investigated bimekizumab, a humanized, full-length IgG1 monoclonal antibody that acts as a dual inhibitor of interleukin (IL)-17A and IL-17F. Methods This was a cross-sectional, observational, retrospective, multicenter analysis. …”
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Decolonization Projects by Cornelius Ewuoso

“…International Journal of Qualitative Methods, 20, 16094069211014766. [10] Abimbola Seye 2023. …”
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Genomic analysis of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) causing infections in children—a Spanish multicenter study by Silvia García-Cobos, Silvia García-Cobos, Natalia Seco Alberca, Blanca Bravo-Queipo-de-Llano, Verónica Casquero-García, Eva Ramírez de Arellano, Eva Ramírez de Arellano, Cristina Calvo, Cristina Calvo, Guillermo Ruíz-Carrascoso, Guillermo Ruíz-Carrascoso, Iker Falces-Romero, Iker Falces-Romero, Nieves Larrosa Escartín, Nieves Larrosa Escartín, Nieves Larrosa Escartín, Belén Viñado-Perez, Belén Viñado-Perez, Miguel Ángel Martínez-López, Susana Melendo Pérez, Enrique Ruíz de Gopegui, Enrique Ruíz de Gopegui, Santiago Pérez Vázquez, Jaime Carrasco-Colom, Belén Aracil García, Belén Aracil García, María Pérez-Vázquez, María Pérez-Vázquez, Ana Méndez-Echevarría, Ana Méndez-Echevarría, Jesús Oteo Iglesias, Jesús Oteo Iglesias

“…These had less than or equal to 5 allele differences by core-genome multilocus sequence typing (cgMLST) analysis or 0–6 core single-nucleotide polymorphisms (SNPs) by core-genome SNP-based analysis. …”
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Architecture and the Time of Space by Deborah Hauptman

“…My interest also developed from a general disposition towards others and world founded in principles of human equality and rights with respect to both freedom and responsibility. …”
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Experimental Investigation on the Influence of the Location of Sand Mining on the Local Scour Characteristics of Bridge Piers by WU Wei, CAI Huiyi, WANG Hao, FU Dabao, CHEN Zetong, YAO Jiateng

“…In this paper, two kinds of flow conditions, four kinds of sand pit positions and local scour tests of piers without sand pit structures were carried out, and the characteristics of scour topography and the variation of local turbulent structure of piers under different working conditions were analyzed.MethodsFirstly, the three-dimensional terrain reconstruction is carried out by using Visual SFM open source software, and the Scale Invariant Feature Transformation method is used to identify and extract the terrain feature points, and the feature points are matched. …”
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Association of Birthweight Discordance with Adverse Birth Outcomes Among Live-Born Twins: A Multi-Center Study in China by Shi B, Tan X, Chen Q, Lu D, Ren S, Huang K, Shen W, Chen Z, Liu J, You C, Li G, Jiang H, Rao H, Qiu J, Wei X, Zhang Y, Lin X, Jiang H, Han S, Wang F, Yang X, Wang Y, Lin N, Lin L, Lin X, Cui Q

“…Birthweight discordance (BWD), a critical complication, remains understudied in its epidemiological context, particularly regarding its population-level associations with adverse neonatal outcomes.Methods: This multi-center, retrospective cohort study leveraged data from 21 hospitals across 18 Chinese cities (2018– 2020) to assess BWD and its epidemiological implications. …”
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Effect of the Foliar Application of Copper Nanoparticles on the Growth and Yield of Persian Leek (Allium ampeloprasum subsp. Persicum) under Salinity Stress by F. Shakarami, S. Mousavi-Fard, A. Rezaei Nejad, F. Beiranvand

“…The soil mixture comprised an equal ratio of agricultural soil, cow manure, and sand, maintaining a clay-sand loam texture. …”
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Developing a Randomised Efficacy PREcision medicine Platform trial design for Cavernomas: the CARE PREP study by Rustam Al-Shahi Salman, Kasia Adamczuk, Richard A Parker, Christopher J Weir, Roberto Latini, Helen Kim, David White, Helen Evans, Jana Bergholtz, Cornelia Lee, Carlos Casaus

“…A trial manager supported the Chief Investigator in growing and leading a multidisciplinary international collaboration, including a patient and public involvement advisory group, in a series of meetings to optimise study design, equality, diversity and inclusion. Edinburgh Innovations established connections with commercial partners with candidate drugs. …”
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A Phase I Dose-Escalation Clinical Trial of Bronchoscopic Cryoimmunotherapy in Advanced-Stage NSCLC by Jun-Chieh J. Tsay, MD, MS, Antonio Velez, MD, Destiny Collazo, BS, Isaac Laniado, MD, Jamie Bessich, MD, Vivek Murthy, MD, Andrew DeMaio, MD, Samaan Rafeq, MD, Benjamin Kwok, MD, Fares Darawshy, MD, Ray Pillai, MD, Kendrew Wong, MD, Yonghua Li, MD, PhD, Rosemary Schluger, RN, Alena Lukovnikova, BS, Sofia Roldan, BS, Matt Blaisdell, BS, Fernanda Paz, Kelsey Krolikowski, BS, Katherine Gershner, MD, Yong Liu, PhD, Judy Gong, BA, Sara Borghi, PhD, Fang Zhou, MD, Aristotelis Tsirigos, PhD, Harvey Pass, MD, Leopoldo N. Segal, MD, MS, Daniel H. Sterman, MD

“…In this first-in-human phase I clinical trial, we investigated the safety and feasibility of bronchoscopic cryoimmunotherapy (BCI) delivered during standard-of-care bronchoscopy and explored associated systemic immune responses. Methods: Subjects with known or suspected advanced-stage NSCLC were recruited. …”
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The ATLAS/NOA-29 study protocol: a phase III randomized controlled trial of anterior temporal lobectomy versus gross-total resection in newly-diagnosed temporal lobe glioblastoma by Matthias Schneider, Anna-Laura Potthoff, Yahya Ahmadipour, Valeri Borger, Hans Clusmann, Stephanie E. Combs, Marcus Czabanka, Lasse Dührsen, Nima Etminan, Thomas M. Freiman, Ruediger Gerlach, Florian Gessler, Frank A. Giordano, Eleni Gkika, Roland Goldbrunner, Erdem Güresir, Hussam Hamou, Peter Hau, Sebastian Ille, Max Jägersberg, Naureen Keric, Maryam Khaleghi-Ghadiri, Ralph König, Jürgen Konczalla, Harald Krenzlin, Sandro Krieg, Aaron Lawson McLean, Julian P. Layer, Jens Lehmberg, Vesna Malinova, Bernhard Meyer, Hanno S. Meyer, Dorothea Miller, Oliver Müller, Christian Musahl, Barbara E. F. Pregler, Ali Rashidi, Florian Ringel, Constantin Roder, Karl Rössler, Veit Rohde, I. Erol Sandalcioglu, Niklas Schäfer, Christina Schaub, Nils Ole Schmidt, Gerrit A. Schubert, Clemens Seidel, Corinna Seliger, Christian Senft, Julia Shawarba, Joachim Steinbach, Veit Stöcklein, Walter Stummer, Ulrich Sure, Ghazaleh Tabatabai, Marcos Tatagiba, Niklas Thon, Marco Timmer, Johannes Wach, Arthur Wagner, Christian Rainer Wirtz, Katharina Zeiler, Thomas Zeyen, Patrick Schuss, Rainer Surges, Christine Fuhrmann, Daniel Paech, Matthias Schmid, Yvonne Borck, Torsten Pietsch, Rafael Struck, Alexander Radbruch, Christoph Helmstaedter, Robert Németh, Ulrich Herrlinger, Hartmut Vatter

“…Discussion The ATLAS/NOA-29 trial aims to determine whether ATL provides superior outcomes at equal patients’ Qol compared to GTR in anterior temporal lobe glioblastoma, potentially establishing ATL as the surgical approach of choice for isolated temporal glioblastoma and redefining the standard of care for this patient population. …”
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Search for the in-situ production of $$^{77}$$ 77 Ge in the GERDA neutrinoless double-beta decay experiment by M. Agostini, A. Alexander, G. Araujo, A. M. Bakalyarov, M. Balata, I. Barabanov, L. Baudis, C. Bauer, S. Belogurov, A. Bettini, L. Bezrukov, V. Biancacci, E. Bossio, V. Bothe, R. Brugnera, A. Caldwell, S. Calgaro, C. Cattadori, A. Chernogorov, P.-J. Chiu, T. Comellato, V. D’Andrea, E. V. Demidova, N. Di Marco, E. Doroshkevich, M. Fomina, A. Gangapshev, A. Garfagnini, C. Gooch, P. Grabmayr, V. Gurentsov, K. Gusev, J. Hakenmüller, S. Hemmer, W. Hofmann, J. Huang, M. Hult, L. V. Inzhechik, J. Janicskó Csáthy, J. Jochum, M. Junker, V. Kazalov, Y. Kermaïdic, H. Khushbakht, T. Kihm, K. Kilgus, I. V. Kirpichnikov, A. Klimenko, K. T. Knöpfle, O. Kochetov, V. N. Kornoukhov, P. Krause, V. V. Kuzminov, M. Laubenstein, M. Lindner, I. Lippi, A. Lubashevskiy, B. Lubsandorzhiev, G. Lutter, C. Macolino, B. Majorovits, W. Maneschg, G. Marshall, M. Misiaszek, M. Morella, Y. Müller, I. Nemchenok, M. Neuberger, L. Pandola, K. Pelczar, L. Pertoldi, P. Piseri, A. Pullia, C. Ransom, L. Rauscher, M. Redchuk, S. Riboldi, N. Rumyantseva, C. Sada, S. Sailer, F. Salamida, S. Schönert, J. Schreiner, A.-K. Schütz, O. Schulz, M. Schwarz, B. Schwingenheuer, O. Selivanenko, E. Shevchik, M. Shirchenko, L. Shtembari, H. Simgen, A. Smolnikov, D. Stukov, S. Sullivan, A. A. Vasenko, A. Veresnikova, C. Vignoli, K. von Sturm, T. Wester, C. Wiesinger, M. Wojcik, E. Yanovich, B. Zatschler, I. Zhitnikov, S. V. Zhukov, D. Zinatulina, A. Zschocke, K. Zuber, G. Zuzel, GERDA collaboration

“…New digital signal processing methods were employed to select and analyze pile-up signals. …”
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Calculating Permutation Entropy without Permutations by Alexander K. Vidybida

“…The characteristic features of this method are as follows: it preserves information about equal values, if any, in the embedding vectors; it is exempt from combinatorics; and it delivers the same entropy value as does the permutation method, provided the embedding vectors do not have equal components. …”
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The Correlation of Non-alcoholic Fatty Liver Disease with Visceral Fat Area and Thyroid Nodules in Patients with Type 2 Diabetes Mellitus by ZENG Jialing, MENG Yan, DENG Tingting, LI Jinhua, ZHAO Ping

“…VFA predicts NAFLD in T2DM patients with the optimal cut-off value of 88.4 cm2, which is equal in females and 99.45 cm2 in males.…”
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脑静脉窦血栓形成患者动态脑血流自动调节受损：基于TCD和默读刺激的评估 Impaired Dynamic Cerebral Autoregulation in Patients with Cerebral Venous Sinus Thrombosis: Evaluation Using Transcranial Doppler and Silent Re... by 陈松伟1，2，3*，陈虹秀1，2，3*，段建钢4，崔柳平1，2，3，刘然1，2，3，邢英琦1，2，3（*第一作者） (CHEN Songwei1,2,3*, CHEN Hongxiu1,2,3*, DUAN Jiangang4, CUI Liuping1,2,3, LIU Ran1,2,3, XING Yingqi1,2,3 (*contributed equally) )

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ALBI Grade Enables Risk Stratification for Bleeding Events and Refines Prognostic Prediction in Advanced HCC Following Atezolizumab and Bevacizumab by Stefanini B, Fulgenzi CAM, Scheiner B, Korolewicz J, Cheon J, Nishida N, Ang C, Marron TU, Wu YL, Saeed A, Wietharn B, Rimassa L, Pirozzi A, Cammarota A, Pressiani T, Pinter M, Balcar L, Huang YH, Mehan A, Phen S, Vivaldi C, Salani F, Masi G, Bettinger D, Vogel A, Schönlein M, von Felden J, Schulze K, Wege H, Samson A, Galle PR, Kudo M, Manfredi GF, Celsa C, Awosika N, Cortellini A, Singal AG, Sharma R, Chon HJ, Tovoli F, Piscaglia F, Pinato DJ, D'Alessio A

“…Overall survival (OS) stratified by ALBI was estimated using the Kaplan-Meier method and the predictive value for the 6-months OS landmark with ROC curves.Results: Of the 368 patients included in the analysis, 163 (44.3%), 192 (52.2%) and 13 (3.5%) had ALBI 1, ALBI 2, and ALBI 3, respectively. …”
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