The Impact of Gut Microbiota on Chronic Obstructive Pulmonary Disease: A Dual-Sample Mendelian Randomization Study by Niu N, Zhao J, Li H, Miao Y, Chen F, Liu J, Cao L, Ji T, Gao F, Xie S, Zhang Y

“…Hence, we conducted a dual-sample Mendelian randomization study to elucidate the impact of gut microbiota on COPD.Methods: We utilized single-nucleotide polymorphisms (SNPs) as instrumental variables, and the Inverse Variance Weighted (IVW) method for primary analysis. …”
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Prognostic Significance of Elevated Platelet Count (>200 x 10^9 per L) in BCLC Stages B and C of Hepatocellular Carcinoma: A Retrospective Multicenter Analysis by Munker S, Rodriguez I, Bernhart K, Ben Khaled N, Findik M, Siegmund LK, Ye L, Reiter FP, Roessler D, Nasseh D, Balcar L, Pomej K, Scheiner B, Weiss C, Pinter M, Seidensticker M, Mayerle J, Philipp AB, De Toni EN

“…However, recent evidence suggests that elevated platelet count may also predict worse outcomes in advanced stages, suggesting a stage-dependent prognostic impact.Aim: This study evaluated the prognostic role of platelet counts across BCLC stages, adjusted for portal hypertension, to improve individualized patient management.Methods: In this retrospective, multicenter study, platelet count of 1112 patients with HCC in different tumor stages was analyzed. …”
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Acupuncture as adjunctive therapy for acute cerebral infarction: a randomized clinical trial by Jiang-Peng Cao, Jiang-Peng Cao, Jiang-Peng Cao, Xin-Yue Du, Xiao-Xi Liu, Xiao-Xi Liu, Meng-Han Li, Meng-Han Li, Man Zhang, Sheng-Xuan Guo, Sheng-Xuan Guo, Qiu-Han Cai, Qiu-Han Cai, Jia-Xin Zhang, Jia-Xin Zhang, Jia-Xin Zhang, Shan-Shan Sun, Shan-Shan Sun, Shan-Shan Sun, Jia-Wei Han, Lin-Ling Chen, Na Zheng, Lan-Yu Jia, Gui-Ping Li, Gui-Ping Li, Yuan-Hao Du, Yuan-Hao Du

“…We aimed to investigate the efficacy and safety of acupuncture as adjunctive therapy to improve neurological function in patients with ACI.MethodsThe multicenter, sham-controlled, patient- and assessor-blinded randomized controlled trial was conducted in 4 tertiary hospitals in China from January to September 2024. …”
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Can Synthetic Data Allow for Smaller Sample Sizes in Chronic Urticaria Research? by Annika Gutsche, Pascale Salameh, Samad S. Jahandideh, Mehran Roodsaz, Serkan Kutan, Ali Salehzadeh‐Yazdi, Emek Kocatürk, Stamatios Gregoriou, Simon F. Thomsen, Kanokvalai Kulthanan, Papapit Tuchinda, Joachim Dissemond, Alicja Kasperska‐Zajac, Magdalena Zajac, Mateusz Zamłyński, Martijn vanDoorn, Claudio A. S. Parisi, Jonny G. Peter, Cascia Day, Cathryn McDougall, Michael Makris, Daria Fomina, Elena Kovalkova, Nikolai Streliaev, Gerelma Andrenova, Marina Lebedkina, Maryam Khoskhkui, Mehraneh M. Aliabadi, Andrea Bauer, Lea Kiefer, Melba Muñoz, Karsten Weller, Pavel Kolkhir, Martin Metz

“…Smaller subgroups of the data were equally replicated and followed the same distribution as RWD. …”
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Improving health-promoting workplaces through interdisciplinary approaches. The example of WISEWORK-C, a cluster of five work and health projects within Horizon-Europe by Deborah De Moortel, Michelle C Turner, Ella Arensman, Alex Binh Vinh Duc Nguyen, Víctor Gonzalez

“…The project is a collaboration between five countries (Austria, Belgium, Greece, the UK, and Sweden) and entails a cross-national mixed-methods intervention study with an embedded process and impact evaluation. …”
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Pathway Of Low Anterior Resection syndrome (LARS) relief after Surgery (POLARiS): protocol for an international, open-label, multi-arm, phase 3 randomised superiority trial within... by Deborah D Stocken, Charles H Knowles, Jared Torkington, David Jayne, Julie Hepburn, Laura Knight, Neil Corrigan, Julie Cornish, Katie Gordon, Ashley Douglas, Kate Wilson, Megan Dale, Julie Croft, Christina Lloydwin, Alexandra Harriet Coxon-Meggy, Judith White, Alun Meggy, Aaron Quyn, Emily Farrow, Kheng-Seong Ng, Hannah Mather, Huey Yi Chong, Betty Tan, Ralph Powell, Andrea Warwick

“…Participants entering the RCT will be randomised between OCM, TAI or SNM, all with equal allocation ratios.Cohort and RCT participants will be followed up for a 24-month period, completing a series of questionnaires measuring LARS symptoms and QoL, as well as clinical review for those in the RCT. …”
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The Activity of Influenza Viruses during 2017-2018 Season in Russia and Countries of the Northern Hemisphere: Conflict by the B-virus Vaccine Component by D. K. Lvov, E. I. Burtseva, E. A. Mukasheva, L. V. Kolobukhina, S. V. Trushakova, N. V. Breslav, E. L. Feodoritova, L. N. Merkulova, K. G. Krasnoslobotsev, E. O. Morozova, I. T. Fedyakina, A. V. Aristova, R. V. Vartanian, L. B. Kisteneva, A. G. Prilipov, S. V. Alkhovsky, A. G. Rosatkevich, I. S. Kruzhkova, A. L. Belyaev, E. V. Axselrod, M. V. Bazarova, S. V. Smetanina

“…The epidemic season had its own peculiarities: delayed and long-term activity of three influenza viruses, the share participation of which was almost equal, with some dominance of the influenza A(H1N1)pdm09 virus by the end of the season. …”
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First-phase ejection fraction is associated with myocardial fibrosis in the pressure overloaded heart by Shukun He, Shukun He, Jingrong Jiang, Jingrong Jiang, Yanting Zhang, Yanting Zhang, Tianshu Liu, Tianshu Liu, Wenhui Deng, Wenhui Deng, Yuji Xie, Yuji Xie, Wenqu Li, Wenqu Li, Yuting Tan, Yuting Tan, Lingyun Fang, Lingyun Fang, Jing Zhang, Jing Zhang, Lin He, Lin He, Qiaofeng Jin, Qiaofeng Jin, Yuman Li, Yuman Li, Li Zhang, Li Zhang, Phil Chowienczyk, Mingxing Xie, Mingxing Xie, Haotian Gu, Jing Wang, Jing Wang

“…Rats in the sham and MTAC groups were equally divided into different time points for examination, respectively. …”
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Serum taurine affects lung cancer progression by regulating tumor immune escape mediated by the immune microenvironment by Tu-Liang Liang, Hu-Dan Pan, Pei-Yu Yan, Jia-Ning Mi, Xiao-Cui Liu, Wei-Qian Bao, Li-Rong Lian, Cui-Fen Zhang, Ying Chen, Jing-Rong Wang, Ying Xie, Hua Zhou, Xiao-Jun Yao, Pawlec Graham, Elaine Lai-Han Leung, Liang Liu, Run-Ze Li

“…Results: Low doses of taurine, as well as taurine-infused beverages at equivalent doses, significantly enhanced lung tumor growth. Equally intriguing is that the promoting effect of taurine on lung cancer progression wanes as the dosage increases. …”
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One-Year Evaluation of Paliperidone Palmitate 6-Monthly: Satisfaction and Perceived Effectiveness Among Patients, Relatives, and Clinicians by Manchado Perero S, Rodríguez Lorente A, García-Pérez A, Isidro García G, Forcen-Muñoz LA, Ovejero S, Sáez Povedano R, González-Galdámez AL, Iturralde LM, Bonilla MR, Fuentes-Pérez P, Ovejas-Catalán C, Suárez-Pinilla P, Fernandez Abascal Puente B, Omaña Colmenares M, Campos-Navarro MP, Baca-García E, Fernández AL, Benavente-López S, Platero AR, Navalón MB, Sánchez-Alonso S, Vázquez-Bourgon J, Pappa S, García-Carmona JA

“…Therefore, we aimed to evaluate the perspectives, including the perceived effectiveness and satisfaction of patients, their relatives and mental health professionals on the twice-yearly treatment with PP6M in usual clinical practice.Methods: The cohort of patients derived from the P2Y study. …”
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Studying and Comparing the Soil Characteristics of Gullies (Case Study: Chabar and Sistan Region) by Mansour Jahantigh, Marzieh Tabe

“…The amount of t for pH in the areas equals to 3.642. There is no statistically significantdifferenceamong the means in level 0.05 (p>0.05). …”
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Solving the K-subset summation problem based on twice quantum searching by YE Tianyu, WU Heng, GAN Zhigang

“…Simulation experimental results turn out that the proposed method achieves an accuracy of no less than 89%, which is higher than that of existing methods.…”
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The effects of surgeon handedness on the efficacy and safety of proximal femoral nail antirotation fixation for intertrochanteric femur fractures in elderly patients: A single Cent... by Xiao-Feng Liu, Xiao-Feng Liu, Xiao-Feng Liu, Xiao-Feng Liu, Yong-Qiang Zheng, Yong-Qiang Zheng, Liang Lin, Liang Lin, Zhen-Yu Lin, Zhen-Yu Lin, Hong-Peng Zhang, Hong-Peng Zhang, Xiao-Peng Huang, Xiao-Peng Huang, Ze-Feng Wang, Ze-Feng Wang, Yang-Zhen Fang, Yang-Zhen Fang, Wen-Ming Zhang, Wen-Ming Zhang, Wen-Ming Zhang, Wen-Ming Zhang, Xin-Yu Fang, Xin-Yu Fang, Xin-Yu Fang, Xin-Yu Fang, Jin-Shan Zhang, Jin-Shan Zhang

“…Equal numbers of left and right PFNA fixation were performed by four surgeons, two right-handed and two left-handed. …”
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A comparative analysis of clinical outcomes in hematological patients afflicted with bacteremia attributable to carbapenem-resistant Klebsiella pneumoniae versus Escherichia coli by Jiali Wang, Jiali Wang, Jia Liu, Qingsong Lin, Qingsong Lin, Fengkui Zhang, Fengkui Zhang, Yizhou Zheng, Yizhou Zheng, Zhijian Xiao, Zhijian Xiao, Jianxiang Wang, Jianxiang Wang, Aiming Pang, Aiming Pang, Yi He, Yi He, Erlie Jiang, Erlie Jiang, Sizhou Feng, Sizhou Feng, Mingzhe Han, Mingzhe Han, Weihua Zhai, Weihua Zhai

“…Nevertheless, there is a paucity of studies that have undertaken a comparative analysis of clinical outcomes in patients afflicted with CRKP and EC.MethodsThis study was conducted with the aim of identifying the microbiological and clinical characteristics of hematological patients suffering from bacteremia caused by CRKP and CREC.ResultsThe cohort included 90 patients with equal proportions of CRKP BSI and CREC BSI from 2017 to 2022. …”
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Exploring the predictive value of serum lipids for short‐term prognosis in patients with acute‐on‐chronic liver failure by Yunfeng Fu, Kaini Wu, Sicheng Yang, Yuanping Fan, Jianhao Qiu, Qi Zhu, Yating Pan, Xiaqin Chen, Sihai Chen, Xiaodong Zhou

“…A comparison of NRI calculated using the cutoff values assigned by equal assignment revealed that the addition of HDL‐C improved the predictive ability of the MELD score by 4.6% (NRI = 0.0460, p = 0.036). …”
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Pomalidomide in relapsed and refractory multiple myeloma: multicenter retrospective study by V. G. Potapenko, E. V. Baumert, A. A. Bobrova, R. V. Vashchenkov, N. V. Dorofeeva, K. D. Kaplanov, E. V. Karyagina, A. N. Levanov, A. S. Luchinin, S. I. Moiseev, A. V. Novitskii, A. S. Nizamutdinova, О. V. Pirogova, S. A. Povzun, М. V. Platonov, V. V. Porunova, D. А. Ptashnikov, V. V. Ryabchikova, S. Ya. Simeniv, I. А. Skorokhod, Е. А. Ukrainchenko, D. А. Chaginskaya, T. V. Shelekhova, M. N. Shirokova, A. A. Shutylev, N. V. Medvedeva

“…To evaluate efficacy, safety and optimal course of the therapy with pomalidomide in routine practice in patients with double refractory multiple myeloma.Materials and methods. Overall, 71 patients with double refractory multiple myeloma were included in the retrospective analysis. …”
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Win Ratio in Biomedical Science: A Bibliometric Analysis by Zhenyu Li, MSc, Aliya Izumi, HBSc, Dominique Vervoort, MD, MPH, CPH, MBA, Anika Ranadive, HBSc, Subodh Verma, MD, Stephen E. Fremes, MD, MSc

“…Background: The win ratio (WR), introduced in 2012, has emerged as a method to analyze hierarchical composite outcomes by prioritizing clinically significant events, unlike traditional composite time-to-event analyses, which treat events equally. …”
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The effect of language typology on the students’ writing skills: A case of the undergraduate students of Arabic language and literature at Arak University by Tahereh Khanabadi, Isa Motaghizadeh, Hayat Ameri, hadi nazarimonazam

“…Dabir Moghadam et al. (2021), focusing on the typological components of word order, identified similarities and differences between Persian and Arabic for the purpose of teaching Persian grammar to the Arabic-speaking learners of Persian.   Materials and methods This study is a quasi-experimental research employing a descriptive-analytical method. …”
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Mir-218-5p from Extracellular Vesicles of Endometrium in Patients with Recurrent Implantation Failure Impairs Pre-Implantation Embryo Development by Cai L, Lv M, Wei J, Liu C, Li Y, Liao Z, Li T, Zhang H, Xi L, Sui C

“…Our findings revealed that miR-218-5p disrupted mouse embryo development, and this effect could be reversed by engineered extracellular vesicles (E-EVs) containing anti-miR-218-5p.Methods: The percentage of blastocyst development and hatching rates, embryo morphology, and the total cell number were measured. …”
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Muqarada sukuk as an Investment Tool in Endowment Funds and the Possibility of its Application in Iraq an Analytical Study by Ardawan Mustafa Ismael, Abdulrrahman Ibrahim Ubaeed

“…Among the contemporary methods for investing endowments are Muqarada instruments, as they are an Islamic alternative to investment bonds in usurious banks, and the first to be used by the Jordan Islamic Bank in the eighties of the last century, and they represent common shares in the speculative capital, which is of equal value, and has a prospectus that contains all the information required by Sharia, such as knowledge of the capital and distribution of profits, and it is tradable in the stock market if it mostly represents assets and benefits. …”
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