Optimizing Haploidentical Hematopoietic Stem Cell Transplantation: Enhancing Outcomes in Hematologic Malignancies in Resource-Limited Settings by Owattanapanich W, Karoopongse E, Kittivorapart J, Meeudompong U, Sathapanapitagkit N, Kungwankiattichai S, Vittayawacharin P, Jianthanakanon J, Donsakul N, Bundhit R, Kongsomchit C, Poonmee N, Luangtrakool P, Warindpong T, Chamsai S, Bintaprasit W, Atakulreka S, Kunacheewa C

“…Over the first year, eight patients with blood cancers, including acute leukemia and lymphoma, received this treatment. A specialized method was applied to reduce complications and improve success rates. …”
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Analysis of Factors Affecting Quality of Life (QoL) in Middle-Aged Stroke Patients (Under 65 Years Old) in the Rehabilitation Phase: Multivariate Regression Analysis by Lumbantobing VBM, Priastomo M, Kosasih CE, Rhamelani P, Anggadiredja K, Adnyana IK

“…Valentina Belinda M Lumbantobing,1,2,* Mukti Priastomo,1 Cecep Eli Kosasih,3 Putri Rhamelani,4 Kusnandar Anggadiredja,1 I Ketut Adnyana1,* 1Department of Pharmacology and Clinical Pharmacy, School of Pharmacy, Institut Teknologi Bandung, Bandung, West Java, Indonesia; 2Department of Fundamental Nursing, Faculty of Nursing, Universitas Padjadjaran, Bandung, West Java, Indonesia; 3Department of Critical Nursing, Faculty of Nursing, Universitas Padjadjaran, Bandung, West Java, Indonesia; 4Faculty of Nursing, Universitas Padjadjaran, Sumedang, West Java, Indonesia*These authors contributed equally to this workCorrespondence: Valentina Belinda M Lumbantobing, Department of Pharmacology and Clinical Pharmacy, School of Pharmacy, Institut Teknologi Bandung, Bandung, West Java, Indonesia, Email valentina@unpad.ac.id I Ketut Adnyana, Department of Pharmacology and Clinical Pharmacy, School of Pharmacy, Institut Teknologi Bandung, Bandung, West Java, Indonesia, Email ketut@itb.ac.idPurpose: This study analyzed factors influencing the quality of life (QoL) in stroke patients during the rehabilitation phase so that rehabilitation professionals, caregivers, and stroke patients can pay attention to all aspects that contribute significantly to a better QoL and can design appropriate interventions to improve patient welfare and support a more significant recovery process.Patients and Methods: A non-experimental quantitative approach with a cross-sectional design was conducted with 76 adult stroke patients in the rehabilitation phase. …”
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Targeted Delivery of Exosome-Derived miRNA-185-5p Inhibitor via Liposomes Alleviates Apoptosis and Cuproptosis in Dilated Cardiomyopathy by Xu S, Zeng Y, Tan X, Zhang G, Xu A, Fan H, Yu F, Qin Z, Song Y, Jiang Y, Wang X, Zhang D, Nong Y, Lian D, Tang J, Zhou Y

“…This study explores a novel treatment strategy involving the delivery of exosome-derived miRNA-185-5p inhibitors encapsulated in liposomes, aiming to target cardiac tissue and alleviate myocardial apoptosis and cuproptosis in DCM.Methods: The miRNA-185-5p inhibitor, identified in our previous study and extracted from exosomes, was encapsulated in liposomes functionalized with a cardiac-targeting peptide. …”
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Silencing NEDD4L Effectively Inhibits the Malignant Behaviors of Hepatocellular Carcinoma by Dai J, Zhu T, Wan J, Liu R, Song Y, Zhang D, Wang X, Zhang H, Li W, Lin J, Zhu X, Liu Y

“…However, research focusing on its involvement in hepatocellular carcinoma (HCC) remains relatively scarce.Methods: This investigation examined NEDD4L’s expression, survival implications, and regulatory mechanisms of NEDD4L in HCC using RNA-seq and microarray data across multiple databases. …”
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Association Between Fractional Exhaled Nitric Oxide (FeNO) and Cognitive Function in Patients with Obstructive Sleep Apnea by Zhu Q, Huang L, Zhu L, Zhang X, Ji H, Niu D, Ji W, Ma Q, Chen R, Shi H, Wang Y, Xu L

“…This study aimed to investigate the association between fractional exhaled nitric oxide (FeNO), a non-invasive marker of airway inflammation, and memory performance in patients with OSA.Methods: A total of 102 participants were enrolled: 62 with moderate or severe OSA (apnea-hypopnea index, AHI≥ 15) and 40 with snoring or mild OSA (AHI < 15). …”
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Transhumanism and New Challenges in Political Theories by Matin Anjomrooz, Mohammad Khezri

“…Sub-questions focus on the impact of transhuman technologies on notions of sovereignty, democracy, human rights, and national identity.Methods: This research employs an analytical-descriptive method, with a focus on content analysis of philosophical and political texts. …”
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Hs-CRP, Diabetic Status, and Adverse Events Among Patients Receiving Statin Therapy Following PCI—A Prospective Registry-Based Study by Chen X, Wang HY, Sun W, Lin Z, Qiao Z, Bian X, Yin D, Feng L, Zhu C, Song W, Wang H, Jia L, Dong Q, Dou K

“…This study aims to evaluate the impact of T2DM on the relationship between residual inflammatory risk, as assessed by a simple, economical, and easily measurable biomarker—high-sensitivity C-reactive protein (hs-CRP)—and clinical outcomes in statin-treated coronary heart disease (CHD) patients with drug-eluting stent (DES) implantation.Patients and Methods: 8,628 individuals with CHD treated with statins and DES implantation at Fuwai Hospital were included. …”
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Invasive Vagus Nerve Stimulation Activates Microglia α7nAChR to Reduce Striatal Neuroinflammation in Mouse Model of Parkinson's Disease and Its Mechanism by GENG Yao, WANG Ruiyu, ZHU Zhuang, SHEN Ying, ZHANG Kezhong

“…After a 1-week recovery period post-surgery, the PD model was induced by subcutaneous injection of MPTP saline solution (20 mg/kg) combined with intraperitoneal injection of probenecid (250 mg/kg) in the MPTP, VNS and Sham groups. The equal volume of normal saline was injected in the control group using the same method twice a week for 5 weeks. …”
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Development and Validation of a Diagnostic Model for Stanford Type B Aortic Dissection Based on Proteomic Profiling by Zhao Z, Chen T, Liu Q, Hu J, Ling T, Tong Y, Han Y, Zhu Z, Duan J, Jin Y, Fu D, Wang Y, Pan C, Keyoumu R, Sun L, Li W, Gao X, Shi Y, Dou H, Liu Z

“…This study focused on developing a model to improve the diagnosis in a population.Patients and Methods: Serum biomarkers were investigated in 88 participants using proteomic profiling combined with machine learning. …”
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TACE Combined with Lenvatinib-PD-1 Versus TACE Monotherapy as Conversion Therapy Before Liver Resection in Unresectable Hepatocellular Carcinoma: A Retrospective, Propensity Score... by Lu C, Liu R, Zhang Y, Luo J, Luo C, Jiang Z, Huang M, Qiu C, Chen J

“…Our aim was to compare the clinical benefits of TACE combined with Lenvatinib-PD-1 inhibitor versus TACE monotherapy as conversion therapy for patients with uHCC who subsequently underwent liver resection (LR).Materials and Methods: This retrospective study included 213 uHCC patients who underwent LR after receiving either TACE combined with Lenvatinib plus PD-1 inhibitor (combination group, n=109) or TACE monotherapy (monotherapy group, n=104). …”
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Propolis-Based Nanostructured Lipid Carrier of α-Mangostin for Promoting Diabetic Wound Healing in Alloxan-Induced Mice by Suhandi C, Wilar G, Mohammed AFA, Mahmoud SA, Muchtaridi M, Shamsuddin S, Safuan S, Lesmana R, Hasan N, Zulhendri F, Wathoni N

“…In vitro release studies were conducted using a dialysis bag method and analyzed using kinetic models. Cytotoxicity was assessed using the WST-8 assay on NIH-3T3 fibroblast cells. …”
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Investigation of Population Changes and Determination of the Bean Pod Borer Helicoverpa armigera (Lepidoptera:Noctuidae) Peak in Bean Phaseolus vulgaris Linnaeus Fields by Pheromon... by Sedighe Ashtari

“…Traps were placed at a height equal to the tallest part of the plant using wooden stakes. …”
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Co-Production of KPC-2 and NDM-5 in a Carbapenem-Resistant Klebsiella Pneumoniae Clinical Isolate: Genetic Insights and Risks by Xia Y, Zhou P, Gao H, Wu X, Zhou Y, Han W, Wan C, Wu Q, Ding J, Yu F

“…Understanding the genetic drivers of resistance and transmission is critical.Methods:  A multidrug-resistant CRKP strain, KP3T58, co-harboring blaKPC-2 and blaNDM-5, was isolated from an ICU patient. …”
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Effect of Remimazolam versus Propofol on Hemodynamics in Elderly Hypertensive Patients Undergoing Gastroenteroscopy: A Multicenter, Randomized Controlled Clinical Trial by Gu Q, Zeng D, Lin D, Zou J, Sun J, Wang H, Chen S, Zhang H, Xu B, Liu W, Shu J

“…Qian Gu,1,2,* Deling Zeng,3,* Dayong Lin,4,* Jiang Zou,5,* Jiaxin Sun,1 Huaiming Wang,1 Shiwei Chen,2 Hongwei Zhang,1 Bo Xu,1 Wusong Liu,6 Jinjun Shu1 1Department of Anesthesiology, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, People’s Republic of China; 2Department of Anesthesiology, Xichang People’s Hospital, Xichang, People’s Republic of China; 3Health Management Center, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, People’s Republic of China; 4Department of Anesthesiology, Sichuan Provincial People’s Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, People’s Republic of China; 5Department of Anesthesiology, Sichuan Women’s and Children’s Hospital/Women’s and Children’s Hospital, Chengdu Medical College, Chengdu, People’s Republic of China; 6Department of Endoscopy Center, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jinjun Shu, Department of Anesthesiology, Sichuan Cancer Hospital, No. 55, Section 4, South Renmin Road, Chengdu, 610041, People’s Republic of China, Email shujinjun@scszlyy.org.cn Wusong Liu, Department of Endoscopy Center, Sichuan Cancer Hospital, No. 55, Section 4, South Renmin Road, Chengdu, 610041, People’s Republic of China, Email liuwusong@scszlyy.org.cnPurpose: This study aimed to compare the effects of remimazolam and propofol on hemodynamics in elderly hypertensive patients undergoing gastroenteroscopy.Methods: In this multicenter, single-blind, randomized clinical trial, 220 hypertensive patients (65– 75 years) scheduled for gastroenteroscopy were randomly assigned to receive either remimazolam (group R, n=110; 0.3 mg/kg induction followed by 0.2– 1 mg/kg/h maintenance) or propofol (group P, n=110; 1.5 mg/kg induction followed by 2– 6 mg/kg/h maintenance), both combined with 0.1 μg/kg sufentanil. …”
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Analysis of the Regulatory Effects of lncRNAs on Kidney Tissue in Ascites Susceptible Broiler by Kasra Ahmadian, Mohammadreza Nassiry, Karim Hasanpur, Ali Javadmanesh

“…Total RNA extraction was done individually using trizol (YTzol) solution, and then an equal amount of RNA from four tissue samples was combined and then cDNA was prepared from 4 ascites tissue samples and 4 healthy tissue samples. …”
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Modelling of circumferential surface topography of grinding wheel with random distribution of circular truncated cone abrasive grains by Xiaodong CHEN, Dexiang WANG, Feng GUO, Xinming LI, Jingliang JIANG

“…Then, a collision detection method is used to check whether there is interference between the abrasive grains, that is, the distance between the centers of the small circular surfaces of any two adjacent truncated cone abrasive grains should be greater than or equal to the sum of the radii of the large circular surfaces of the two abrasive grains. …”
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Associations Among Obstructive Sleep Apnea, Thyroid Function and Morphology Changes by Xie Y, Zhang H, Cao Z, Zhou Y, Lu C, Yin L, Zhu S, Su Y, Niu X, Ma L, Yuan Y, Zhang Y, Wang Z, Liu H, Ren X, Shi Y

“…Yushan Xie,1,2,* Hongli Zhang,3,* Zine Cao,1,* Yanuo Zhou,1,2 Chendi Lu,1,2 Libo Yin,4 Simin Zhu,1,2 Yonglong Su,1,2 Xiaoxin Niu,1,2 Lina Ma,1,2 Yuqi Yuan,1,2 Yitong Zhang,1,2 Zitong Wang,1,2 Haiqin Liu,1,2 Xiaoyong Ren,1,2 Yewen Shi1,2 1Department of Otorhinolaryngology—Head and Neck Surgery, The Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an, People’s Republic of China; 2Shaanxi Provincial Key Laboratory for Precision Diagnosis and Treatment of Otorhinolaryngology, Xi’an, People’s Republic of China; 3Department of Ultrasound, The Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an, People’s Republic of China; 4Otolaryngology Head and Neck Surgery Department, Xi’an Central Hospital, Xi’an, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xiaoyong Ren, The Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an, People’s Republic of China, Email renxiaoyong@sina.vip.com Yewen Shi, The Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an, People’s Republic of China, Email shiyewen59@outlook.comPurpose: This study unveils the complex interplay among obstructive sleep apnea (OSA), thyroid function, and morphological changes.Methods: Data from 1,102 patients were collected retrospectively from the Department of Otorhinolaryngology—Head and Neck Surgery of the Second Affiliated Hospital of Xi’an Jiaotong University from 2012 to 2023. …”
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Investigation of Smoking Cessation Status and Its Influencing Factors in Patients with Chronic Obstructive Pulmonary Disease by Fan M, Fang YJ, Chen J, Zhong X, Zhang N, Zeng Z, Xiao D, Qi X, Liang W, Li X, Gao Y, Li S, Su Z

“…This study aimed to investigate the status quo and influencing factors of smoking cessation in patients with SAD or COPD, which is crucial for improving prevention and treatment of chronic airway diseases.Patients and Methods: In this multicenter, prospective cohort investigation, questionnaire survey and one-year follow-up study were conducted in SAD and COPD patients with smoking history. …”
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Antimicrobial efficacy of methylene blue-functionalized graphene oxide-mediated photodynamic therapy against Enterococcus faecalis in root canal disinfection by Rizwan Jouhar, FCPS, Mohamad S. Halim, M.Res.Dent, Sayed A. Quadri, MD, Muhammad A. Ahmed, PhD, Faheem Shah, PhD

“…Six experimental groups with equal numbers of samples (n = 15) were treated with 5 % NaOCl (groups 1 and 2), MB-based PDT (groups 3 and 4), or MB/rGO-based PDT (groups 5 and 6). …”
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Clinical Relevance of Elevated Serum Carcinoembryonic Antigen in Allergic Bronchopulmonary Aspergillosis/Mycosis: A Multicenter Retrospective Study by Ge H, Cai R, Chen X, Liu B, Hu X, Deng S, Li H, Dai L, Tang J, Tang H, Gong X, Wu C, Wang G, Li G, Liu B, Wang J, Tang Y, Li X, Feng J

“…Few studies on ABPA/M cases presenting with elevated serum CEA levels have been reported.Patients and Methods: A cohort of 115 patients diagnosed as ABPA/M were divided into two groups (CEA normal and CEA elevated). …”
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