The Role of Applying Metagenomic Next-Generation Sequencing (mNGS) in Periprosthetic Joint Infection with Sinus Tract: A Retrospective Study by Yuan X, Wang Q, Ding H, Li H, Fang X, Zhang W, Huang Z

“…We evaluated mNGS’s role in diagnosing and guiding treatment for PJI with sinus tracts.Methods: This retrospective analysis included 52 PJI patients (2019– 2024). …”
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Development and Validation of the CHD-PEBBS: A Scale to Assess Perceived Exercise Benefits and Barriers in Coronary Heart Disease Patients by Liu Y, Feng L, Wang L, Li H, Tu H, Li X, Zhang X, Zhang L, Yang M, Sun X, Huang T, Xiong Y

“…There is a lack of validated tools to assess coronary heart disease (CHD) patients’ exercise perception.Purpose: The aim of this study is to develop a scale assessing CHD patients’ perceived exercise benefits and barriers (CHD-PEBBS) and test its reliability and validity.Methods: A total of 205 CHD patients were recruited for a cross-sectional survey. …”
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Perspectives on Enhanced Measurement-Based Care Among Healthcare Providers, Adults, Adolescent Patients with Major Depressive Disorder and Pediatric Family Members: A Multicenter O... by Zhang H, Sun P, Wang X, Yang X, He Y, Yang T, Su Y, Fu Y, Li Q, Sun J, Liu J, Murphy JK, Michalak EE, Lam RW, Chen J, Fang Y

“…This study aimed to identify the barriers and facilitators of enhanced MBC (eMBC) in the outpatient setting to clarify the eMBC utilization dilemma.Methods: Between September 2022 and June 2023, we collected the opinions of healthcare providers, adult and adolescent patients, and family members of adolescent patients via online surveys. …”
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СРАВНЕНИЕ ВЛИЯНИЯ ДЛИТЕЛЬНОЙ ТЕРАПИИ, ОСНОВАННОЙ НА КАРВЕДИЛОЛЕ И БИСОПРОЛОЛЕ, НА МЕТАБОЛИЧЕСКИЕ ПАРАМЕТРЫ И ЭРЕКТИЛЬНУЮ ФУНКЦИЮ У БОЛЬНЫХ АРТЕРИАЛЬНОЙ ГИПЕРТОНИЕЙ И ИЗБЫТОЧНОЙ МАС... by S. Y. Martsevich, S. N. Tolpygina

“…Aim — to compare the antihypertensive efficacy, effect on blood glucose, uric acid, index of insulin resistance levels, lipid profile and effect on erectile function of long-term therapy, based on carvedilol and bisoprolol in patients with AH 1−2 deg. and overweight/obesity.Materials and methods. Type of research: clinical, multicenter, randomized, open, comparative, stepped, in two parallel groups. …”
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Efficacy and Safety of Bushen Jiedu Tongluo Decoction in Active Rheumatoid Arthritis: Study Protocol for a Multi-Center, Randomized, Double-Blind, Controlled Trial by He Y, Shen J, Wu H, Chen L, Zhou Q, Wang Q, Guo Y, Wu F, Pan X

“…Therefore, we designed a multi-center, randomized, double-blind, placebo-controlled study, to scientifically evaluate the clinical efficacy and safety of BSJDTL for active RA.Methods: This was a multi-center, randomized, double-blind placebo-controlled trial. …”
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A New Strategy for the Treatment of Patients With Prolonged Impairment of Consciousness Using Xenon. Prospective Pilot Study by A. I. Shpichko, A. N. Kuzovlev, R. A. Cherpakov, N. P. Shpichko, O. A. Grebenchikov, A. K. Yevseyev, A. K. Shabanov, S. S. Petrikov

“…Patients were randomized into two equal groups. In group I (comparisons, n=15) (in addition to the standard treatment after a traumatic brain injury), each patient included in the study underwent 7 sessions of inhalation of an air-oxygen mixture with an oxygen content of at least 30 vol% for 30 minutes. …”
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COMPARATIVE EVALUATION OF THE LABORATORY STUDY RESULTS OF THE ADHESION STRENGTH OF A-SILICONE LINING MATERIAL IN THE PRODUCTION OF TWO-LAYER REMOVABLE PROSTHESES by I. Yanishen, P. Zapara, О. Fedotova

“…However, it was found that the index of the bond strength of the "PM-S" with the plastic "Pallopress" is equal to (5.5 ± 0.3) kgf / cm2, which is significantly (p <0,05) higher than the contact the material is "Villacryl H Plus" - (5.1 ± 0.2) kgf / cm2. …”
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Effect of Resistance Training on Hepatic Bile Acid, beta-Klotho Protein and Expression of Farnesoid X Receptor, Fibroblast Growth Factor 15 and Fibroblast Growth Factor Receptor 4... by Mehri Gholipour, Najme Rezaeian, Mohammad Karimi, Sadegh Cheragh-Birjandi

“…This research was carried out to study the effect of eight weeks of resistance training on liver bile acid (BA), beta klotho protein (KLB) and the expression of farnesoid X receptor (FXR), fibroblast growth factor 15 (FGF15) and fibroblast growth factor receptor 4 (FGFR4) in male rats with non-alcoholic fatty liver disease. Materials and Methods: In this study, 16 male Wistar rats (age, six-weeks and weight, 120-160 gr) after induction of NAFLD conditions, with six weeks of high-fat diet were randomly divided into two equal groups (n=8 in each group) of Control (C), and resistance training (R). …”
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Adenovirus Nanoparticles Displaying RBD Induce a Protective Immune Response Against BA.5 in Mice by Mo C, Wang Z, Liu D, Yang X, Zhang Q, Ye L, Yuan S, Deng S, Lai Z, Huang D, Yang Y, Xu D, Yuan J, Zhu Y, Liu H, Zhou C, Liao X, Li X, Liu W, Zhou R, Tian X

“…Hexon is the major capsid protein, and multiple hypervariable regions (HVRs) have been used for displaying exogenous antigens and inducing a strong antibody responses.Methods: We utilized SpyCatcher/SpyTag technology to incorporate SpyTag into HVR2, 4, and 7 of the hexon of the bivalent vaccine strain rAd3/7, respectively, to construct recombinant Ad, rAd3/7-SpyTag. …”
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Prognostic Implications of Red Blood Cell Distribution Width to Albumin Ratio in Myelofibrosis: A 10-Year Multicenter and Retrospective Study by Zeng T, Zheng Z, Qian H, Liu L, Shi X, Shao Y, Huang Z, Li R, Wen B, Han Q, Feng Q, Tu L, Bao X, Tong H, Jin J, Huang J

“…The red cell distribution width to albumin ratio (RAR), a novel biomarker indicative of inflammation, has emerged as a strong prognostic indicator in the general population but remains unexplored in MF.Methods: We retrospectively enrolled 504 consecutive MF patients from 7 hematological centers over a 10-year period. …”
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Abstract 062: N20 Potential And Imaging Biomarkers Of Functional Recovery In Acute Ischemic Stroke Patients And EVT by Alicia Martinez Piñeiro, Giuseppe Lucente, María Hernandez‐Perez, Jordi Cortés, Andrea Arbex, Meritxell Gomis Cortina, Laura Dorado Bouix, Natalia Pérez de la Ossa, Alba Ramos‐Fransi, Miriam Almendrote, Carlos Castaño, Sebastián Remollo, Maria Rosa García Sort, Patricia Cuadras Collsamata, Mónica Millán, Antoni Dávalos

“…This secondary study aims to describe the association between the N20 response and imaging biomarkers of ischemic penumbra, infarct volume and collateral flow. Methods Presence and amplitude of the N20 response was recorded before EVT. …”
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Establishing Sitafloxacin Epidemiological Cut-off Values (ECOFFs) for Clinical Bacterial Isolates by Zhang J, Li X, Jia X, Li Y, Zheng B, Yu Y, Hu F, Sun Z, Chen Z, Zhang G, Kang W, Wang T, Li J, Gao H, Yi Q, Yu W, Chu X, Xu Y, Yang Q

“…The minimum inhibitory concentrations (MICs) and inhibition zone diameters of sitafloxacin for all isolates were determined by using the broth microdilution method (BMD) and the disk diffusion method according to European Committee on Antimicrobial Susceptibility Testing (EUCAST) guidelines. …”
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Clinical Characteristics of Auditory Mismatch Negativity in Patients with Chronic Disorders of Consciousness Following Intracerebral Haemorrhage: A Prognostic Prediction Study by Lv X, Yang N, Lv J, Li L, Gao Y, Xiang Z, Li Z, Lang X, Tao D, Zhao Y, Duan H, Li H

“…Xuehai Lv,1,&amp;ast; Nuan Yang,2,&amp;ast; Jingwei Lv,3 Linxi Li,4 Yuemin Gao,5 Zhengmao Xiang,6 Zhengfan Li,4 Xiaoguang Lang,5 Dan Tao,7 Yuqin Zhao,5 Haili Duan,5 Hongling Li1 1Second Department of Rehabilitation Medicine, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei Province, 050000, People’s Republic of China; 2Graduate School, Hebei Medical University, Shijiazhuang, Hebei Province, 050017, People’s Republic of China; 3School of Basic Medicine, Hebei Medical University, Shijiazhuang, Hebei Province, 050017, People’s Republic of China; 4Graduate school, Hebei North University, Zhangjiakou, Hebei Province, 075000, People’s Republic of China; 5Department of Clinical Rehabilitation Medicine, Handan Central Hospital, Handan, Hebei Province, 056001, People’s Republic of China; 6Graduate school, Chengde Medical University, Chengde, Hebei Province, 067000, People’s Republic of China; 7Academy of Geography, Sociology, and International Studies, Hong Kong Baptist University, Hong Kong, 519000, People’s Republic of China&amp;ast;These authors contributed equally to this workCorrespondence: Hongling Li, Second Department of Rehabilitation Medicine, The Second Hospital of Hebei Medical University, No. 215 of Hepingxi Road, Xinhua District, Shijiazhuang, Hebei Province, 050000, People’s Republic of China, Tel +86 15803210622, Email lihongling_lhl@163.comObjective: To examine the clinical features of auditory mismatch negativity (MMN) and its potential utility in prognostic prediction in patients with chronic disorders of consciousness (DOC) following intracerebral haemorrhage (ICH).Methods: Between September 2023 and July 2024, 24 patients with chronic DOC following ICH were recruited. …”
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Evaluation of Environmental Effects of Applied Pesticides on Canola (Brassica napus L.), Sugar Beet (Beta vulgaris L.), and Potato (Solanum tuberosum L.) Fields in Ali Abad Katool... by Zahra Deilam, Hossein Kazemi, Maral Niazmoradi, Javid Gherekhloo

“…The highest environmental effect of pesticides per hectare belongs to Mancozeb fungicide with EIQ-FUR equal to 61.72. This fungicide has an average EIQ (25.72) compared to pesticides such as Cyproconazole+Carbendazim, Chlorpyrifos and Diazinon, etc., but due to the high percentage of the effective substance and the amount used in the potato fields of the region (3 liters per hectare), causes the most damage and toxicity to the environment. …”
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Mechanism of magnesium sulfate suppressing vascular calcification in rats with chronic renal failure through TLR4/NF-κB pathway by Dong Li-ming, Li Yin-hui, Li Li

“…ObjectiveTo explore the effect of magnesium sulfate on vascular calcification （VC） in rats with chronic renal failure （CRF） through the pathway of Toll-like receptor 4 （TLR4）/nuclear transcription factor-κB （NF-κB）.MethodsA total of 50 Sprague-Dawley （SD） rats were randomized into five groups of control， model， magnesium sulfate-L （25% magnesium sulfate， 2 mL）， magnesium sulfate-H （25% magnesium sulfate， 4 mL） and magnesium sulfate-H+PDTC （25% magnesium sulfate， 4 mL+NF-κB inhibitor PDTC， 100 mg/kg） （<italic>n</italic>=10 each）. …”
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Specific features of cognitive skill development in athletes of situational sports by Vyacheslav Romanenko, Yrui Tropin, Leonid Podrigalo, Natalya Boychenko, Anatoly Abdula, Nataliia Sereda, Yaroslav Yatsiv

“…The formation of cognitive skills in athletes engaged in situational sports follows specific patterns determined by the characteristics of gameplay or competitive activity, as well as by the influence of psychophysiological and individual traits. An equally important factor in the development of cognitive skills is the training process, which incorporates specialized exercises and techniques aimed at stimulating cognitive processes, situational analysis, spatial imagination, and adaptive behavior. …”
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Problematic Social Media Use, Self-Objectification, and Body Image Disturbance: The Moderating Roles of Physical Activity and Diet Intensity by Çınaroğlu M, Yılmazer E

“…It also explores the psychological outcomes of depression and anxiety.Methods: A cross-sectional study was conducted with 594 women aged 18– 65 in Istanbul, Türkiye. …”
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The Role of L-Sorbose Metabolism in Enhancing Fitness and Virulence in Escherichia coli Under Acidic Conditions by Qiu T, Chen X, Deng X, Zhang G, Wen S, Wu J, Sun D, Li T, Yan B, Dai M, Zhong LL, Tian GB

“…While metabolic flexibility is critical for E. coli fitness to host environments, the role of secondary carbon sources like L-Sorbose remains poorly characterized.Methods: The functional importance of L-Sorbose metabolism in E. coli CFT073 was investigated under acidic conditions simulating gastrointestinal and urinary tract environments. …”
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Transcriptomic Changes and Pathological Mechanisms in Familial and Sporadic Idiopathic Restless Legs Syndrome: Implications for Inflammation and Cell Adhesion Molecules by He XR, Song JM, Zhao JP, Zhang J, Feng JT, Chen SQ, Zhou ZY, Wang HM, Zhang Y, Feng Y, Wu YC, Zhu XY

“…The study aims to investigate transcriptomic changes and underlying pathological mechanisms in familial and sporadic idiopathic RLS to uncover potential contributors to its pathogenesis.Patients and Methods: This study included 37 RLS patients, 39 unrelated healthy controls and 19 healthy relatives of RLS patients with a positive family history. …”
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A Nomogram for Diagnosing Ventilator-Associated Pneumonia Using Circulating Inflammation Indicators in ICU Patients by Yang J, Bao W, Wang H, Zhou J, Hu Q, Wang Y, Li Y

“…Jiajia Yang,1,&ast; Weiyuan Bao,2,&ast; Hongmei Wang,1 Jie Zhou,3 Qiang Hu,4 Ying Wang,1 Yuancheng Li5 1Department of Infection Management, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, Suzhou, 215008, People’s Republic of China; 2Department of Logistics Support, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, Suzhou, 215008, People’s Republic of China; 3Intensive care unit, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, Suzhou, 215008, People’s Republic of China; 4Department of Respiratory and Critical Care Medicine, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, Suzhou, 215008, People’s Republic of China; 5Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Jiangsu Key Laboratory of Molecular Biology for Skin Diseases and STIs, Nanjing, 210042, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Ying Wang, Department of Infection Management, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, No. 242, Guangji Road, Suzhou, 215008, People’s Republic of China, Email wangy830224@sina.com Yuancheng Li, Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Jiangsu Key Laboratory of Molecular Biology for Skin Diseases and STIs, Nanjing, Jiangsu, 210042, People’s Republic of China, Email ycli@pumcderm.cams.cnPurpose: To construct a risk nomogram model of ventilator-associated pneumonia (VAP) patients with mechanical ventilation in the intensive care unit (ICU) based on peripheral blood inflammatory indicators and to evaluate its diagnostic value.Patients and Methods: A matched 1:2 case: control study was conducted. …”
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