A Clinical Risk Score Based on Albumin and Electrolyte Levels for Predicting Death Risk in Hospitalized Elderly COVID-19 Patients by Wang C, Zheng X, Bi S, Shao M, Xie Z, Wei N, Zhou Q, Feng S

“…Patients were classified into low- and high-risk groups using optimal segmentation thresholds, with survival curves generated by the Kaplan–Meier method. An online risk calculator was developed to facilitate real-time risk assessment in clinical settings.Results: The cohort included 1413 hospitalized COVID-19 patients. …”
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Application of Intravoxel Incoherent Motion in the Prediction of Intra-Tumoral Tertiary Lymphoid Structures in Hepatocellular Carcinoma by Ma L, Liao S, Zhang X, Zhou F, Geng Z, Hu J, Zhang Y, Zhang C, Meng T, Wang S, Xie C

“…., Ltd, Beijing, People’s Republic of China; 4Central Research Institute, United Imaging Healthcare, Shanghai, People’s Republic of China; 5Center of Hepato-Pancreato-Biliary Surgery, the First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, 510080, People’s Republic of China*These authors contributed equally to this workCorrespondence: Chuanmiao Xie, Department of Radiology, Sun Yat-sen University Cancer Center, Guangzhou, 510060, People’s Republic of China, Email xchuanm@sysucc.org.cn Shutong Wang, Center of Hepato-Pancreato-Biliary Surgery, Center of Hepato-Pancreato-Biliary Surgery, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, 510080, People’s Republic of China, Email wangsht23@mail.sysu.edu.cnObjective: To explore the value of intravoxel incoherent motion (IVIM) sequences in predicting intra-tumoral tertiary lymphoid structures (TLSs).Materials and Methods: This prospective study pre-operatively enrolled hepatocellular carcinoma (HCC) patients who underwent magnetic resonance imaging including IVIM sequences, between January 2019 and April 2021. …”
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Identification and Validation of Epithelial Cell Centre Regulatory Transcription Factors in the Gastric Cancer Microenvironment by Su G, Wang J, Liu S, Fu X, Li Y, Pan G

“…Guomiao Su,1,* Juan Wang,2,* Shiyue Liu,1,* Xiaonan Fu,1 Yanxi Li,1 Guoqing Pan1 1Department of Pathology, The First Affiliated Hospital of Kunming Medical University, Kunming, Yun Nan, People’s Republic of China; 2Clinical Laboratory, Yunnan Province Third People’s Hospital, Kunming, Yun Nan, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yanxi Li; Guoqing Pan, Department of Pathology, The First Affiliated Hospital of Kunming Medical University, Kunming, Yun Nan, People’s Republic of China, Email liyanxicuhk@163.com; guoqing_pan@163.comPurpose: To identify the epithelial cell centre regulatory transcription factors in the gastric cancer (GC) microenvironment and provide a new strategy for the diagnosis and treatment of GC.Methods: The GC single-cell dataset was downloaded from the Gene Expression Omnibus (GEO) database. …”
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Mindfulness-based programmes for mental health promotion in adults in nonclinical settings: A systematic review and meta-analysis of randomised controlled trials. by Julieta Galante, Claire Friedrich, Anna F Dawson, Marta Modrego-Alarcón, Pia Gebbing, Irene Delgado-Suárez, Radhika Gupta, Lydia Dean, Tim Dalgleish, Ian R White, Peter B Jones

“…Other preventative interventions may be equally effective. Implementation of MBPs in nonclinical settings should be partnered with thorough research to confirm findings and learn which settings are most likely to benefit.…”
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Comparison of the Impact of tNGS with mNGS on Antimicrobial Management in Patients with LRTIs: A Multicenter Retrospective Cohort Study by Li D, Li Q, Huang Z, Wu W, Fan X, Liu J, Li R, Zhang Q, Su X

“…However, the impact of tNGS and mNGS on antimicrobial stewardship in patients with LRTIs remains unclear.Methods: Patients diagnosed with LRTIs who underwent tNGS or mNGS between June 2021 and January 2024 were included. …”
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Platelet Membrane-Coated Poly (Lactic-Co-Glycolic Acid) Nanoparticles as a Targeting Drug Delivery System for Multidrug-Resistant Breast Cancer by Song B, Na YG, Kim BJ, Jin M, Song YH, Kim DE, Hwang S, Baek JS, Lee HK, Cho CW

“…To overcome these challenges, we developed a triple-functionalized nanocarrier system incorporating poly(lactide-co-glycolide) (PLGA)-based nanoparticles (PNs), D-α-tocopheryl polyethylene glycol succinate (TPGS) for P-gp inhibition, and platelet membrane (PM) coating for targeted tumor delivery.Methods: The PM-coated TPGS-modified PNs with PTX (PTPNs) was characterized by particle size analysis, transmission electron microscopy (TEM), and protein assay to confirm PM coating. …”
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Integrating CEUS Imaging Features and LI-RADS Classification for Postoperative Early Recurrence Prediction in Solitary Hepatocellular Carcinoma: A Machine Learning-Based Prognostic... by Liang L, Pang J, Zhang B, Que Q, Gao R, Wu Y, Peng J, Zhang W, Bai X, Wen R, He Y, Yang H

“…Li Liang,1,2,* Jinshu Pang,1,* Bulin Zhang,2 Qiao Que,1 Ruizhi Gao,1 Yuquan Wu,1 Jinbo Peng,1 Wei Zhang,2 Xiumei Bai,1 Rong Wen,1 Yun He,1 Hong Yang1 1Department of Medical Ultrasound, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi Zhuang Autonomous Region, People’s Republic of China; 2Department of Medical Ultrasound, Liuzhou People’s Hospital, Liuzhou, Guangxi Zhuang Autonomous Region, People’s Republic of China*These authors contributed equally to this workCorrespondence: Hong Yang, Department of Medical Ultrasound, The First Affiliated Hospital of Guangxi Medical University, No. 6 Shuangyong Road, Nanning, Guangxi Zhuang Autonomous Region, People’s Republic of China, Tel +8607715356706, Email yanghong@gxmu.edu.cn Yun He, Department of Medical Ultrasound, The First Affiliated Hospital of Guangxi Medical University, No. 6 Shuangyong Road, Nanning, Guangxi Zhuang Autonomous Region, People’s Republic of China, Tel +8607715356706, Email heyun@gxmu.edu.cnPurpose: To develop and validate a machine learning (ML) model for predicting early postoperative recurrence in hepatocellular carcinoma (HCC) patients by integrating contrast-enhanced ultrasound (CEUS) features with Liver Imaging Reporting and Data System (LI-RADS) classification.Materials and Methods: A retrospective analysis was conducted on data from 279 patients who underwent surgical resection for HCC. …”
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APPLICABILITY OF SIMILARITY CONDITIONS TO ANALOGUE MODELLING OF TECTONIC STRUCTURES by Mikhail A. Goncharov

“…Belousov as a «realist» as he supported «the liberal point of view» [Methods of modelling…, 1988, p. 21–22], whereas M.V. …”
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The Correlation Between the Expression Levels of Serum miR-19b and SOCS-1 mRNA and Clinical Symptoms in Patients with Allergic Rhinitis by Kang Z, Di L, Liu Y, Qu W, Zeng Y, Lu X, Wang L

“…Zhaopeng Kang,1,* Lingling Di,2,* Yi Liu,3 Wei Qu,3 Yi Zeng,3 Xue Lu,3 Lixin Wang3 1Department of Andrology, Renmin Hospital, Hubei University of Medicine, Shiyan, Hubei, 442000, People’s Republic of China; 2Department of Otolaryngology Head and Neck Surgery, General Hospital of Ningxia Medical University, Yinchuan, Ningxia Hui Autonomous Region, 756099, People’s Republic of China; 3Department of Otolaryngology Head and Neck Surgery, Renmin Hospital, Hubei University of Medicine, Shiyan, Hubei, 442000, People’s Republic of China*These authors contributed equally to this workCorrespondence: Lixin Wang, Department of Otolaryngology Head and Neck Surgery, Renmin Hospital, Hubei University of Medicine, No. 39 Chaoyang Middle Road, Shiyan, Hubei, 442000, People’s Republic of China, Tel +86-719-8666352, Email 1043275363@qq.comObjective: To investigate the correlation between the expression levels of microRNA-19b (miR-19b) and suppressor of cytokine signaling 1 messenger RNA (SOCS-1 mRNA) in the serum of patients with allergic rhinitis (AR) and clinical symptoms.Methods: This prospective study included a total of 86 patients with allergic rhinitis who were admitted to the People’s Hospital Affiliated to Hubei University of Medicine from January 2022 to January 2023. …”
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The First Case of Antimicrobial-Resistant Salmonella Stanley ST29 Diagnosed Secondary to Acute Cholecystitis by Wang W, Liu S, Zhang M, Chen Y, Liang Y, You S, Lv P, Xu X, Zhang F

“…Wenqing Wang,1,2,* Shufen Liu,3,* Minlan Zhang,3 Yan Chen,4 Yanru Liang,1,2 Shuqi You,1,2 Peijun Lv,4 Xuebin Xu,5 Fenghua Zhang3 1Department of Microbiology, Shanghai Pudong New Area Center for Disease Control and Prevention (Shanghai Pudong New Area Health Supervision Institute), Shanghai, People’s Republic of China; 2Fudan University Pudong Institute of Preventive Medicine, Shanghai, People’s Republic of China; 3Department of Laboratory Medicine, Zhoupu Hospital Affiliated to Shanghai University of Medicine and Health, Shanghai, People’s Republic of China; 4Department of Microbiology, Panzhihua City Center for Disease Control and Prevention, Panzhihua, People’s Republic of China; 5Division of Pathogen Testing and Analysis, Shanghai Center for Disease Control and Prevention, Shanghai, People’s Republic of China*These authors contributed equally to this workCorrespondence: Fenghua Zhang, Email zpyyzfh@163.comObjective: To analyze the phenotypic and genomic characteristics of a non-typhoidal Salmonella bile isolate from a patient with chronic diarrhoea secondary to acute cholecystitis.Methods: The patient presented with chronic diarrhoea lasting for two weeks, which was secondary to acute cholecystitis. …”
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Digital Inclusion Pathways and Influencing Factors Among Older Adults in Outpatient Settings: A Grounded Theory Study by Chen Y, Yin Q, Zhou T, Gu S, Xie L, Xiao M, Wang L, Zhao Q

“…This study aims to investigate the experiences, attitudes, and perceptions of older adults in outpatient regarding smart healthcare service in order to develop an explanatory digital inclusion pathway and construct a comprehensive path model for older adults.Patients and Methods: We conducted semi-structured interviews with 27 older adults in outpatients in Chongqing, China to understand their experiences, attitudes, and perceptions of attending smart healthcare services through theoretical sampling. …”
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Integrating Deep Learning and Radiomics in Differentiating Papillary Thyroid Microcarcinoma from Papillary Thyroid Carcinoma with Ultrasound Images by Yu B, He H, Zheng Q, Ai Y, Yu X, Li S, Zhang J, Jin J, Jin X, Yu W

“…Bing Yu,1,2,* Huijuan He,3,* Qiao Zheng,2,* Yao Ai,2 Xianwen Yu,2 Sunjun Li,4 Ji Zhang,2 Juebin Jin,5 Xiance Jin,2,6 Wenliang Yu3 1Purchasing Center Department, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, 310020, People’s Republic of China; 2Radiation and Medical Oncology Department, Wenzhou Medical University First Affiliated Hospital, Wenzhou, 325000, People’s Republic of China; 3Radiation Oncology Department, Quzhou People’s Hospital, Quzhou, 324002, People’s Republic of China; 4Alberta College, Wenzhou Medical University, Wenzhou, 325000, People’s Republic of China; 5Medical Engineering Department, Wenzhou Medical University First Affiliated Hospital, Wenzhou, 325000, People’s Republic of China; 6School of Basic Medical Science, Wenzhou Medical University, Wenzhou, 325000, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xiance Jin, Radiation and Medical Oncology Department, Wenzhou Medical University First Affiliated Hospital, Wenzhou, 325000, People’s Republic of China, Email jinxc1979@hotmail.com Wenliang Yu, Radiation Oncology Department, Quzhou People’s Hospital, Quzhou, 324002, People’s Republic of China, Email wlyu1982@aliyun.comPurpose: The feasibility and accuracy of ultrasound-based radiomics, deep learning, and combined deep learning radiomics models were investigated in the differentiation of papillary thyroid carcinoma and papillary thyroid microcarcinoma to decrease the risk of overtreatment of papillary thyroid microcarcinoma.Methods: A total of 549 patients with confirmed 180 papillary thyroid carcinoma and 436 papillary thyroid microcarcinoma nodules from Hospital One were enrolled and randomly divided into training and validation cohorts at a ratio of 8:2 with 56 patients left as independent testing set 1. …”
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Long Non-Coding RNA EPB41L4A-AS1 Serves as a Diagnostic Marker for Chronic Periodontitis and Regulates Periodontal Ligament Injury and Osteogenic Differentiation by Targeting miR-2... by Li R, Huang Z, Chen M

“…Rui Li,1,* Zhibin Huang,2,* Mengmeng Chen3 1Department of Stomatology, Affiliated Hospital of Nantong University, Nantong, People’s Republic of China; 2Medical Room, Nantong College of Science and Technology, Nantong, People’s Republic of China; 3Department of Stomatology, The Fourth Hospital of Harbin, Harbin, People’s Republic of China*These authors contributed equally to this workCorrespondence: Mengmeng Chen, Department of Stomatology, The Fourth Hospital of Harbin, No. 119, Jingyu Street, Daowai District, Harbin City, Heilongjiang Province, 150026, People’s Republic of China, Tel +86 0451-88029850, Email chenmengm74@163.comBackground: Several long non-coding RNAs (lncRNAs) are dysregulated in chronic periodontitis (CP).Purpose: The study aimed to elucidate the molecular mechanisms and clinical significance of lncRNA EPB41L4A antisense RNA 1 (EPB41L4A-AS1) in CP.Patients and Methods: This study enrolled 101 patients with CP and 90 subjects with healthy periodontal tissues. …”
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Pattern of changes in morpho-densitometric parameters of magnocellular neurons of the hypothalamic paraventricular nucleus under restraint stress of different duration by K. B. Romanova, O. V. Hancheva, Yu. M. Kolesnyk

“…In the nuclei of cells after 6 and 15 weeks of restriction, the content was decreased approximately equally by 37 % and 35 %, respectively, and long-term restriction (21 weeks) contributed to a 41 % decrease. …”
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Effect of perioperative ONS combined with intestinal microecology in patients with colorectal cancer: a randomized clinical trial by Xuanjun Liu, Weixu Mao, Guowei Zhao, Juan Liao, Qigang Li, Gan He

“…PurposeTo investigate the combined effects of oral nutritional supplement (ONS) and intestinal microecology on postoperative nutrition status, inflammatory response and intestinal flora regulation colorectal cancer (CRC) patients.MethodsThis prospective single-center randomized controlled trial (RCT) was conducted at Chongqing Yongchuan Hospital between December 2023 and December 2024. …”
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Enhancing adoptive cancer immunotherapy with Vγ2Vδ2 T cells through pulse zoledronate stimulation by Hong Wang, Mohanad H. Nada, Grefachew Workalemahu, Yoshimasa Tanaka, Craig T. Morita

“…Additionally, IL-15 increases the anti-tumor activity of murine αβ T cells in mice but its effect on the in vivo anti-tumor activity of human Vγ2Vδ2 cells has not been assessed.Methods Human Vγ2Vδ2 T cells were expanded by pulse or continuous zoledronate stimulation with IL-2 or IL-15. …”
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m6A-Methylated NUTM2B-AS1 Promotes Hepatocellular Carcinoma Stemness Feature via Epigenetically Activating BMPR1A Transcription by Li W, Zeng M, Ning Y, Lu R, Wei Y, Xu Z, Wei H, Pu J

“…However, whether m6A has oncofetal characteristics remains unknown.Methods: Gene expression in HCC tissues and cells was detected using qPCR. …”
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Comparative Genomic Analysis of Tigecycline Resistance Development in Clinical Acinetobacter baumannii Isolates by Li X, Liu J, Zhang X, Li J, Xuan L, Yuan S, Li J, Sun Y, Du X

“…The goal is to provide clinical insights into the development of tigecycline resistance in A. baumannii, with a focus on multidrug-resistant strains commonly associated with hospital-acquired infections.Methods: We conducted dynamic tracking of multidrug-resistant Acinetobacter baumannii (MDR-AB) infections in three patients to monitor changes in tigecycline sensitivity during antimicrobial therapy. …”
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Acute tonsillitis and pediatric functional gastrointestinal disorders: the first result of a possible association analysis by E. R. Meskina, L. A. Galkina, T. V. Stashko

“…The aim is to discover a possible relationship between acute exudative tonsillitis and FDDS in children in the context of clinical and medico-social assessment. Materials and Methods: An observational cross-sectional study was performed using the continuous sampling method. …”
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Effect of Uncertainty-Aware AI Models on Pharmacists’ Reaction Time and Decision-Making in a Web-Based Mock Medication Verification Task: Randomized Controlled Trial by Corey Lester, Brigid Rowell, Yifan Zheng, Zoe Co, Vincent Marshall, Jin Yong Kim, Qiyuan Chen, Raed Kontar, X Jessie Yang

“…ResultsA total of 30 participants provided complete datasets. An equal number of participants were in each AI condition. …”
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