Research Status and Direction of Chronic Obstructive Pulmonary Disease Complicated with Coronary Heart Disease: A Bibliometric Analysis from 2005 to 2024 by Bian H, Zhu S, Xing W, Qi L, Xue J, Peng X, Jin Z, Zhao H

“…In this study, we provide valuable insights in the field by examining the evolution of the relationship between COPD and CHD over the past 20 years.Methods: A comprehensive computer search was conducted in the Web of Science (WOS) core dataset, covering literature on COPD combined with CHD from January 1, 2005, to August 20, 2024. …”
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DL-Tryptophan Alleviates Sepsis-Related Acute Liver Injury via AhR Activation by Li B, Wang Q, Hu L, Duan W, Chen Y, Wang Z, Liu C, Liao L

“…Baitian Li,1,* Qing Wang,2,3,* Lungui Hu,3 Wenying Duan,3 Yuxuan Chen,3 Zetian Wang,3 Chunzheng Liu,3 Lijun Liao3 1Department of Emergency Medicine, The Second Affiliated Hospital of Anhui Medical University, Hefei, Anhui, 230601, People’s Republic of China; 2Shanghai YangZhi Rehabilitation Hospital, Shanghai, 201619, People’s Republic of China; 3Department of Pain Management, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, 200433, People’s Republic of China*These authors contributed equally to this workCorrespondence: Lijun Liao, Department of Pain Management, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai, 200120, People’s Republic of China, Email liao@pan-support.com Chunzheng Liu, Department of Pain Management, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai, 200120, People’s Republic of China, Email lcz980712@163.comIntroduction: This research sought to elucidate the extent to which DL-tryptophan may confer protection against sepsis-induced acute liver damage (SALI) and to investigate the underlying mechanisms, particularly emphasizing aryl hydrocarbon receptor (AhR) activation.Methods: Cecal ligation and puncture (CLP) was utilized to create a murine sepsis model. …”
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Exploration of the relationships between the information and communication technology (ICT) and the education system in Morocco by Abdelkarim Taam, Amine Amar, Brahim Hmedna, Khalid Benabbes, El Menzhi Kaoutar, Rachid Daoudi, Adil El Makrani

“…Consequently, countries have adapted several methods of teaching and learning and made continuous reforms for a better quality of education. …”
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Systemic hormonal contraception and risk of venous thromboembolism by Oskari Heikinheimo, Elena Toffol, Timo Partonen, Anna But, Antti Latvala, Jari Haukka

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Exploring the Association Between Immune Cell Phenotypes and Osteoporosis Mediated by Inflammatory Cytokines: Insights from GWAS and Single-Cell Transcriptomics by Kuang S, Ma X, Sun L, Wang C, Li Y, Wang G, Sun J, Zhou F, Zhang C

“…Despite established links between immune cell phenotypes and inflammatory cytokines and osteoporosis, the exact mechanism involved remains unclear, and further understanding is needed for effective prevention and treatment.Methods: Here, we performed a two-sample Mendelian randomization (MR) study to estimate the causal effects between 731 immune cell types, 91 and 41 inflammatory factors (which may have some overlap), and 5 types of osteoporosis. …”
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Gold Nanoparticles Functionalized With 5-Amino-2-Mercaptobenzimidazole: A Promising Antimicrobial Strategy Against Carbapenem-Resistant Gram-Negative Bacteria by Zhang J, Zhang X, Yao Z, Pan J, Ye J, Xia P, Zhou T, Cao J

“…This study introduces 5-amino-2-mercaptobenzimidazole (5-A-2MBI) functionalized gold nanoparticles (5-A-2MBI_Au NPs) and evaluates their antibacterial activity against CR-GNB.Methods: The 5-A-2MBI_Au NPs was synthesized using a one-pot method. …”
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Mitophagy-Related Gene CHDH Predicts Prognosis and Immune Response and Inhibits Proliferation and Migration in vitro and in vivo of Oral Squamous Cell Carcinoma by Chen L, Zhou Z, Guo L, He Z, Luo W, Fu Y, Xiao Q, Liu B, Huang P

“…Mitophagy is a special type of cellular autophagy that plays an important role in tumors, but its role in OSCC is still unclear.Methods: Mitophagy-related genes (MRGs) were obtained from the GeneCards database. …”
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Injectable Nanocomposite Hydrogel for Accelerating Diabetic Wound Healing Through Inflammatory Microenvironment Regulation by Chen Y, Li Y, Song H, Liu X, Zhang H, Jiang J, Liu H, Zhuo R, Cheng G, Fang J, Xu L, Qi Y, Sun D

“…Employing zeolitic imidazolate framework-8 (ZIF-8) as a drug delivery platform, integrated within a temperature-sensitive injectable hydrogel, presents an intriguing strategy for the closure of various irregular wounds, modulation of inflammatory responses, and promotion of angiogenesis.Methods: Herein, ZIF-8 loaded with curcumin (Cur) combined with methylcellulose/carboxymethyl chitosan (MCC) thermosensitive hydrogel was described. …”
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Xingxiao Pill Suppressed the Progression of Non-Small Cell Lung Cancer by Targeting SREBP1/FASN–Induced Fatty Acid Biosynthesis via PI3K/AKT/mTOR Signaling Pathway by Zhou X, Hu X, Zhang Z, Lin S, Lin X, Zhou T, Bai Y, Hu K

“…This study aimed to evaluate the potential efficacy of XXP in treating NSCLC and to investigate how XXP regulates fatty acid biosynthesis in NSCLC.Methods: A lung carcinoma mouse model was created by transplanting Lewis lung carcinoma (LLC) cells into male C57BL/6 mice. …”
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Effect of telemedicine-supported structured exercise program in patients with chronic low back pain: a randomized controlled trial. by Yuan Feng, Chuanmei Zhu, Huizhen Liu, Tianjie Bao, Chongyang Wang, Zezhang Wang, Xiaoyi Wang, Ruishi Zhang, Yujia Zhang, Shaojun Zhang, Lin Yang, Siyi Zhu, Chengqi He

“…Furthermore, the telemedicine program is equally effective as usual care therapy in enhancing mental health status, mental health dimensions of quality of life, walking ability, and exercise adherence. …”
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Impacts of Prior Anti-Osteoporosis Treatments on Sequential Denosumab Responses in BMD Changes Among Postmenopausal Osteoporosis Women in East China: Real-World Data Analysis by Guan G, Du Y, Tang W, Chen M, Yu W, Li H, Cheng Q

“…Guoyu Guan,1 Yanping Du,2,* Wenjing Tang,2 Minmin Chen,2 Weijia Yu,2 Huilin Li,2 Qun Cheng2,* 1Department of Geriatrics, Huadong Hospital, Fudan University, Shanghai, People’s Republic of China; 2Department of Osteoporosis and Bone Disease, Huadong Hospital, Fudan University, Shanghai, People’s Republic of China*These authors contributed equally to this workCorrespondence: Qun Cheng, Department of Osteoporosis and Bone Disease, Huadong Hospital, Fudan University, No. 221, Yan’an West Road, Shanghai, 200040, People’s Republic of China, Email chengqun@fudan.edu.cn Yanping Du, Department of Osteoporosis and Bone Disease, Huadong Hospital, Fudan University, No. 221, Yan’an West Road, Shanghai, 200040, People’s Republic of China, Email yanpingdu@fudan.edu.cnPurpose: This study aimed to investigate the impacts of prior anti-osteoporosis treatments on bone mineral density (BMD) changes in Chinese postmenopausal women with osteoporosis following 1-year Denosumab (Dmab) therapy.Patients and Methods: This retrospective cohort study enrolled 381 postmenopausal women, all receiving a 1-year Dmab treatment. …”
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Altered Structure-Function Coupling Associated with Attention Decline in Shift Work Disorder by Wu Z, Feng S, Li K, Dong L, Zhang L, Ning Y, Yin D

“…This study aimed to examine the role of changed SFC in abnormal attentional network function in SWD.Methods: Thirty-four patients with SWD and thirty-two healthy controls were recruited. …”
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Association Between Daytime Sleepiness and Quality of Life in Chinese Adolescents: A Moderated Mediation of Cognitive Dysfunction and Depressive Symptoms by Li W, Hu N, Yang X, Zheng W, Tong J, Song J, Song Y, Gao X, Wang Z, Liu W, Wang L, Tan Y, Wang C, Deng H

“…However, the interrelationships among these variables remain unclear, particularly regarding whether cognitive function moderates the association between daytime sleepiness and quality of life.Methods: A large-scale cross-sectional survey was conducted among 52,964 students (grades 7– 12) across five geographically diverse regions of China. …”
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Myocardium-to-cavity ratio derived from simultaneous 99mTc-PYP/201Tl dual-isotope SPECT imaging to differentially diagnose transthyretin cardiac amyloidosis by Shozo Yamashita, Kenichi Nakajima, Teppei Kitano, Hiromu Kato, Tatsuya Yoneyama, Haruki Yamamoto, Kunihiko Yokoyama

“…For M/C ratio calculation, circular regions of interest of equal diameter were set on the myocardium and left ventricular cavity using 201Tl images, then superimposed on 99mTc-PYP images. …”
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Exploring the Therapeutic and Gut Microbiota-Modulating Effects of Qingreliangxuefang on IMQ-Induced Psoriasis by Yu Z, Wang Y, Guo Y, Zhu R, Fang Y, Yao Q, Fu H, Zhou A, Ma L, Shou Q

“…Zhengyao Yu,1– 5,* Yingying Wang,2,3,6,* Yingxue Guo,2,3,6 Ruotong Zhu,1,4 Yimiao Fang,1 Qinghua Yao,7 Huiying Fu,2,3,5,6 Ang Zhou,8 Lili Ma,1 Qiyang Shou2,3,5,6 1The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Traditional Chinese Medicine), Hangzhou, Zhejiang, 310006, People’s Republic of China; 2The Second School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, 310053, People’s Republic of China; 3Jinhua Academy, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, 310053, People’s Republic of China; 4The First School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, 310053, People’s Republic of China; 5Yongkang Hospital of Traditional Chinese Medicine, Jinhua, Zhejiang, 321300, People’s Republic of China; 6School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, 310053, People’s Republic of China; 7The Second Affiliated Hospital of Zhejiang Chinese Medical University, Xinhua Hospital of Zhejiang Province, Hangzhou, Zhejiang, 310005, People’s Republic of China; 8Department of Dermatology, Yiwu Central Hospital Medical Community Choujiang Hospital District, Yiwu, Zhejiang, 322000, People’s Republic of China*These authors contributed equally to this workCorrespondence: Lili Ma, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Traditional Chinese Medicine), Hangzhou, Zhejiang, 310006, People’s Republic of China, Email lilyma163@163.com Qiyang Shou, The Second School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, 310053, People’s Republic of China, Email sqy133@126.comPurpose: To investigate the therapeutic and gut microbiota-modulating effects of Qingreliangxuefang (QRLXF) on psoriasis.Materials and Methods: We used network pharmacology, a computational approach, to identify key bioactive compounds and biological targets, and explored the molecular mechanisms of QRLXF. …”
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RESULTS OF TREATMENT OF EDENTULOUS PATIENTS WITH DENTURES MADE OF «FTORAX» by V.M. Dvornyk, H.M. Kuz, O.B. Tumakova, O.S. Shemetov, V.S. Kuz

“…As for the coefficient «K», its value decreased almost twofold compared with the results before prosthetics (2.44±0.14) and equals to 1.25±0.03, which is significantly closer to normal (1,02±0.01). …”
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The results of investigating the efficacy and safety of non-medical switching from the original rituximab to its biosimilar in rheumatoid arthritis patients (AMBIRA study) by M. A. Korolev, Yu. B. Ubshaeva, N. Y. Banshchikova, E. A. Letyagina, A. A. Mullagaliev

“…They were switched to equal-dose biosimilar (Acellbia®) by non-medical reasons and were observed throughout the year. …”
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Biomimetic Aggregation-Induced Emission Luminogens Mediated Effective Phototherapy and Immune Checkpoint Blockade for the Synergistic Treatment of Lung Cancer by Yang L, Wei M, Deng X, He L, Lin Y, Lin X, Zhou D, Li M, Qin A, Zhang L, Ouyang Z

“…However, the disadvantages including hydrophobicity, low specificity, and short circulation lifetime limited their efficacy on cancer therapy.Methods: We developed a biomimetic AIEgens constructed using CD8+ T cells membrane to camouflage the AIEgen C41H37N2O3S2 (named BITT) nanoparticles (termed TB). …”
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The Negative Regulatory Role of Transcriptional Regulator H-NS on the Type VI Secretion System in Acinetobacter baumannii by Zhang Y, Zhou H, Kong J, Hu P, Zhang Y, Cao J, Zhou B

“…We explored potential targets of H-NS mediated silencing or activation within the regulation of A. baumannii T6SS, along with the specific regulatory mechanisms involved, thereby providing a theoretical foundation for further research on A. baumannii invasive infections stemming from mixed infections and the development of therapeutic target.Methods: Using the plasmids pAT04 and pYMAb2-hyg, we constructed A. baumannii ATCC19606 strains with the hns gene knocked out (ABΔhns) and overexpressed (ABhns+). …”
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Using Human‐Centred Design to Codesign Patient Engagement Tools With a Patient Advisory Council: Successes and Challenges by Madelyn Knaub, Santiago Leon, Surakshya Pokharel, Veronika Kiryanova, Kim Giroux, Prachi Khanna, Anna Rychtera, D'Arcy Duquette, Pamela Mathura, Nancy Verdin, Anshula Ambasta

“…PAC members had participated equally in the conduct of a prior qualitative study to understand patient needs about bloodwork processes in hospitals. …”
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