VOPP1 as a Novel Susceptibility Gene in Rheumatoid Arthritis: Insights Into Its Mechanisms From Mendelian Randomization and Experimental Validation by Wu W, Cai H, Nan Y, Tang J, Wang Y

“…In this paper, we identified new susceptibility genes in RA and investigated their underlying mechanisms using integrated Mendelian randomization (MR) analysis.Methods: Two-sample MR analyses were used to determine the causative links among eQTLs, metabolites, and RA risk. …”
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Effects of pelvic obliquity and limb position on radiographic leg length discrepancy measurement: a Sawbones model by Mohammed Nazmy Hamad, Isaac Livshetz, Anshum Sood, Michael Patetta, Mark H. Gonzalez, Farid A. Amirouche

“…In the present study, we sought to characterize the effects of varying degrees of lateral pelvic obliquity (PO) and mediolateral limb movement in the coronal plane on LLD measurement error (ME). Methods A 3‐D sawbones model of the pelvis with bilateral femurs of equal‐length was assembled. …”
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Correlation Between Blood Pressure Variability and Serum Vascular Endothelial Growth Factor Concentration in Patients with Type I Cerebral Small Vessel Disease by Yang H, Wang Q, Li M, Yu J, Li H, Zhang S, Qian H

“…Hua Yang,1,2,* Qianyao Wang,3,* Min Li,1,* Jin Yu,1 Hua Li,1 Shufeng Zhang,1 Hairong Qian3 1Department of Neurology, The First Medical Centre, Chinese PLA General Hospital, Beijing, 100853, People’s Republic of China; 2Key Laboratory of Endocrine Glucose & Lipids Metabolism and Brain Aging, Ministry of Education; Department of Endocrinology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, 250021, People’s Republic of China; 3Navy Clinical College, The Fifth School of Clinical Medicine, Anhui Medical University, Hefei, Anhui, 230032, People’s Republic of China*These authors contributed equally to this workCorrespondence: Hairong Qian, Navy Clinical College, The Fifth School of Clinical Medicine, Anhui Medical University, Hefei, Anhui, 230032, People’s Republic of China, Email qianhairong_cn@163.comObjective: To investigate the relationship between blood pressure variability (BPV) and serum vascular endothelial growth factor (VEGF) levels in patients with type I cerebral small vessel disease (CSVD).Methods: 144 Patients admitted to the Neurology Department of our Hospital between December 2021 and December 2022 were included and categorized into 5 groups according to CSVD burden, which was evaluated based on MRI findings. …”
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Prognostic Role of SETDB2 in Clear Cell Renal Cell Carcinoma: Linking Immune Infiltration, Cuproptosis, and Tumor Suppression by Lu SH, Lui K, Qian Y, Zhou WY, Mu YY, Zhang W

“…SET domain bifurcated histone lysine methyltransferase 2 (SETDB2) belongs to the Su(var)3– 9 subfamily of methyltransferases and has been linked to various forms of cancer, but the role it plays in ccRCC remains to be fully established.Methods: Data on SETDB2 expression were downloaded from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) databases. …”
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Facemask-wearing behavior to prevent COVID-19 and associated factors among public and private bank workers in Ethiopia. by Seada Hassen, Metadel Adane

“…To address this gap and to consider intervention measures that encourage the wearing of facemasks, this study was conducted to identify behaviors of facemask wearing and associated factors among bank workers in Dessie City, Ethiopia.<h4>Materials and methods</h4>An institution-based cross-sectional study was conducted among 413 bank workers who were selected using a simple random sampling technique from January 1st to 30th, 2021 in Dessie City, Ethiopia. …”
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Rates of Multidrug-Resistant Gram-Negative Bacterial Infections in Hospitalized Non-Immunocompromised Pediatric Patients: A 9-Year Retrospective Study at a Lebanese Tertiary Medica... by Zakhour R, Khafaja S, Korman R, Boutros CF, El Zein Z, Chmaisse A, Haj M, Haddara A, El-Houry Z, Jbahi M, Chamseddine S, Bou Karroum S, Al Oweini D, Youssef YS, Youssef N, Nasser M, Fayad D, Abi Farraj F, El Nakib C, Isaac I, Lteif M, Araj GF, Dbaibo GS

“…The objectives of this study were to describe the epidemiology, potential contributing factors, and antimicrobial resistance patterns associated with infections caused by MDR Gram-negative bacteria (GNB) in non-immunocompromised children and adolescents.Methods: This was a retrospective observational study conducted at the American University of Beirut Medical Center (AUBMC) from 2009 to 2017. …”
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The Correlation Between Airborne Pollen and Sensitization in Children with Respiratory Allergic Diseases: A Cross-Sectional Study by Xu L, Dai Y, Luo W, Jiang W, Tan Q, Lu Y, Huang Z, Gu W, Li P, Wang P, Huang L, Sun H, Hao C, Sun B

“…Lina Xu,1,&ast; Yinfang Dai,1,&ast; Wenting Luo,2,&ast; Wujun Jiang,1 Qianlei Tan,1 Yanhong Lu,1 Zhifeng Huang,2 Wenjing Gu,1 Pengyun Li,1 Pengli Wang,1 Li Huang,1 Huiquan Sun,1 Chuangli Hao,1 Baoqing Sun2 1Department of Respiratory Medicine, Children’s Hospital of Soochow University, Suzhou, Jiangsu, People’s Republic of China; 2Department of Allergy and Clinical Immunology, State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Chuangli Hao, Department of Respiratory Medicine, Children’s Hospital of Soochow University, Suzhou, 215003, People’s Republic of China, Email hcl_md@sina.com Baoqing Sun, Department of Allergy and Clinical Immunology, State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong, 510120, People’s Republic of China, Email sunbaoqing@vip.163.comBackground: Pollen is a significant contributor to respiratory allergies worldwide, underscoring the importance of understanding its association with childhood sensitization to enhance clinical management.Objective: This study focuses on investigating the prevalence of various airborne pollens and their correlation with clinical characteristics of childhood respiratory allergic diseases in southeastern China.Methods: From November 2020 to October 2021, this research employed Durham monitoring samplers to collect airborne pollen. …”
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Prevalence of Site-Specific Mycoplasma genitalium Infection and Macrolide and Fluoroquinolone-Associated Mutations in Men Who Have Sex with Men in Shenzhen, China by Leng X, Zhu R, Ao X, Zhou Y, Zhang K, Hu T, Wu J, Chen Z, Huang L, Huang N, Li X, Ahmed Alnour R, Xue Z, Zhang X, Liu H, Axirejiang T, Ke W, Zou H

“…We aimed to assess site-specific MG infection and its correlates and macrolide and fluoroquinolones mutations among men who have sex with men (MSM) in Shenzhen, China.Methods: Samples were obtained from different anatomic sites of MSM based on their sexual behavior. …”
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The Attractive and Deterring Factors for Medical Students Towards Pathology as a Specialty in Saudi Arabia by Samkari A, Qari TA, Abukhairat Jnr SM, AlQarni G, Assiri R, Boraie SA, Alghamdi KT

“…Descriptive statistics and Chi-square tests were used, with significance set at p &lt; 0.05.Results: A total of 612 valid responses were received, with an almost equal distribution of male (49.8%) and female (50.2%) participants. …”
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Factors Associated with Management of Workplace Violence Competence Among Chinese Nursing Interns by Meng L, He L, Ouyang L, Fu M, Li P, He Y

“…Therefore, this study investigated the current status of management of workplace violence competence (MWVC) and identify associated factors affecting their MWVC among nursing interns.Participants and Methods: A total of 817 nursing interns from six tertiary hospitals in Hunan Province, China, participated in this study in July 2023. …”
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Qingwen Hufei Granules Attenuate Lipopolysaccharide-Induced Acute Lung Injury by Suppressing NLRP3 Inflammasome-Dependent Pyroptosis by Long K, Yang Y, Wang Y, Wang B, Zhou H, Liu Y, Li Y, Yang S, Cao L, Huang T, Liu Y, Zhang H

“…However, the active components and mechanism of action of QHG remain unclear.Methods: Lipopolysaccharide (LPS) induced ALI mouse model. …”
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Viral Mimetic Bacterial Outer Membrane Vesicles for Targeting Angiotensin-Converting Enzyme 2 by Ahn G, Yoon HW, Jeong JH, Kim YH, Shin WR, Song MS, Ahn JY

“…To apply refined OMVs for human theranostic applications, we developed naturally exposed receptor-binding domain (RBD) OMVs grafted with antigen 43 as a minimal modular system targeting angiotensin-converting enzyme 2 (ACE2).Methods: We constructed E. coli-derived OMVs using the antigen 43 autotransporter system to display RBD referred to as viral mimetic Ag43β 700_RBD OMVs. …”
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Budget Impact and Cost&ndash;Benefit Analyses of Sodium-Glucose Cotransporter-2 Inhibitors for Patients With Heart Failure in Thailand by Arunmanakul P, Phodha T, Pinta-ay S, Nimworapan M, Phrommintikul A, Thammatacharee N, Dilokthornsakul P

“…Poukwan Arunmanakul,1,2 Tuangrat Phodha,3,&ast; Sakkarin Pinta-ay,1,4 Mantiwee Nimworapan,1,2 Arintaya Phrommintikul,5 Noppakun Thammatacharee,6 Piyameth Dilokthornsakul1,&ast; 1Center for Medical and Health Technology Assessment (CM-HTA), Department of Pharmaceutical Care, Faculty of Pharmacy, Chiang Mai University, Chiang Mai, Thailand; 2Pharmaceutical Care Training Center (PCTC), Department of Pharmaceutical Care, Faculty of Pharmacy, Chiang Mai University, Chiang Mai, Thailand; 3Drug Information and Consumer Protection Center, Center of Excellence in Pharmacy Practice and Management Research, Faculty of Pharmacy, Thammasat University, Rangsit Campus, Pathum Thani, Thailand; 4Department of Pharmacy, Maharaj Nakorn Chiang Mai Hospital, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand; 5Division of Cardiology, Department of Internal Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand; 6Health Systems Research Institute, Nonthaburi, Thailand&ast;These authors contributed equally to this workCorrespondence: Tuangrat Phodha, Drug Information and Consumer Protection Center, Center of Excellence in Pharmacy Practice and Management Research, Faculty of Pharmacy, Thammasat University, Rangsit Campus, Pathum Thani, 99 Paholyothin Road, Khlong Nueng, Khlong Luang District, Pathum Thani, 12120, Thailand, Tel +66 2 986 9214, Email tuangrat25@tu.ac.th Piyameth Dilokthornsakul, Center for Medical and Health Technology Assessment (CM-HTA), Department of Pharmaceutical Care, Faculty of Pharmacy, Chiang Mai University, 239 Suthep, Mueang, Chiang Mai, 50200, Thailand, Tel +66 53 944 342, Email piyameth.dilok@cmu.ac.thPurpose: To assess the budget impact and cost–benefit of incorporating sodium-glucose cotransporter-2 inhibitors (SGLT-2i) into the benefit package for patients with heart failure (HF) under the universal health coverage (UHC) in Thailand.Patients and Methods: A budget impact analysis and cost–benefit model were developed using a five-year time horizon from the payer perspective. …”
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Association Between the Circadian Rhythm of Arterial Blood Pressure and White Matter Lesions in Hospitalized Hypertensive Patients: A Cross-Sectional Study by Shen Y, Xiang W, Chen S, Hou Z, Hong D

“…However, little is known about the relationship between WMLs and altered circadian rhythms of blood pressure (BP) in patients with essential hypertension.Methods: This cross-sectional observational study enrolled patients diagnosed with essential hypertension. …”
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Impact of White Blood Cell Count After Percutaneous Coronary Intervention on Long-Term Prognosis in Patients with Unstable Angina Pectoris: A Single-Center Retrospective Observatio... by Zhang Z, Wang H, Wang R, She Z, Liang X, Liu H, Kou X, Wang S

“…However, the effect of WBC-C after PCI on the long-term prognosis of patients with unstable angina pectoris (UA) is unclear.Methods: A retrospective cohort study was conducted in 1811 consecutive patients with UA. …”
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The Mediating Role of Avoidant Personality Disorder Features in the Relationship Between Stressful Life Events and Depression Among First-Year University Students by Zhou H, Niu S, Guo Y, Qin Y, Sun H, Mu F, Duan X, Zheng Y, Zhang Y, Liu Y, Liu N

“…To explore whether the avoidant personality disorder (AVPD) features play a mediating role between stressful life events (SLEs) and depression among Chinese first-year university students.Methods: The cross-sectional study was conducted from April to October 2018. …”
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Pd Icosahedral Nanoparticles Promote Skin Wound Healing by Enhancing SP1-HBEGF Axis-Mediated Keratinocytes Proliferation by He F, Li M, Zhao H, Zhao H, Meng X, Zhang Y, Tang Y, Huang H, Li J, Xie H, Wang B

“…Thereinto, Pd icosahedra nanoparticles (Pd Icos NPs) and Pd octahedra nanoparticles (Pd Oct NPs) have superior catalytic activity compared to other shapes but the application in skin wound healing have not been studied and reported.Methods: Pd Oct NPs and Pd Icos NPs were synthesized by seed-mediated growth method and one-step synthesis method and characterized by series physical chemical assays. …”
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Population Pharmacokinetic/Pharmacodynamic Study of Linezolid in Hospital-Acquired Pneumonia Patients with Renal Insufficiency by Xu J, Chen X, Zhang Q, Zhuang Z, Yuan Y, Duan L, Shi L, Zhu C, Li J, Lu J, Yu Y, Tang L

“…The objective of this study was to compare the outcomes of linezolid versus teicoplanin in HAP patients with renal insufficiency and to explore optimal dosage strategy for linezolid.Methods: The retrospective study enrolled adult patients treated with intravenous linezolid or teicoplanin at Suzhou Municipal Hospital between July 2018 and August 2023. …”
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The Association Between Medication Adherence, Internalized Stigma and Social Support Among Outpatients with Major Depressive Disorder in a Malaysian Hospital: A Cross-Sectional Stu... by Halim R, Kaur M, Syed Mokhtar SS, Chemi N, Sajatovic M, Tan YK, Siau CS, Ng CG

“…This study aimed to investigate poor adherence prevalence and the demographic and clinical factors associated with poor medication adherence among patients with MDD.Methods: This cross-sectional survey recruited participants using universal sampling from a major hospital in Selangor, Malaysia. …”
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Factors Influencing Mechanical Ventilation and Inpatient Palliative Care Utilization in Patients With Chronic Obstructive Pulmonary Disease by Kao LT, Yang CC, Wu YC, Ko SC, Liang YS, Liao KM, Ho CH

“…In this study, we aimed to investigate inpatient palliative care utilization among hospitalized patients with COPD requiring mechanical ventilation and examine the associated risk factors and clinical outcomes.Patients and Methods: A retrospective nested case-control study was conducted using population-based claims datasets from 2017 to 2021. …”
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