The Role of Circulating Fatty Acids in Mediating the Effect of Insomnia on Heart Failure: A Two-Step, Two-Sample Mendelian Randomization Study by Zuo B, Yu B, Wang P, Zhang C, Zhao C, Sun Y, Ai S

“…This study aims to investigate the mediating role of fatty acids in the association between insomnia and heart failure.Methods: We performed two-step, two-sample Mendelian randomization analysis by applying SNPs as genetic instruments for exposures, mediators and outcomes. …”
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European civil procedure: current status within the legal system of the European Union and its member states by V. Terekhov

“…In order to guarantee an equal level of judicial protection everywhere in the EU a procedural “bill of rights” is required, and it needs to be adopted at the “highest level” of the system.Conclusions. …”
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Competition Between Protein and DNA for Binding to Natural Sepiolite Nanofibers by Adame Brooks D, Piétrement O, Dardillac E, Castro Smirnov FA, Aranda P, Ruiz-Hitzky E, Lopez BS

“…In this study, we analyzed the adsorption of DNA and proteins to sepiolite by analyzing the competition among these biomolecules during the adsorption process.Methods: To determine the binding of sepiolite to proteins, we used BSA and a monoclonal antibody (mAb) against the CD4 membrane antigen as a model. …”
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Analysis of Risk Factors and Development of a Predictive Model for Delirium in ICU Patients: Construction, Validation, and Clinical Implications by Li X, Zhang W, Wang T, Qiu Z, Sun X, Qu W, Zhang G

“…Xia Li,1,* Weisong Zhang,2,3,* Tao Wang,4 Zhengfeng Qiu,1 Xuan Sun,1 Wenhao Qu,1 Guopei Zhang1 1Department of Intensive Care Unit, Affiliated Hospital 6 of Nantong University, Yancheng Third People’s Hospital, Yancheng, 224000, People’s Republic of China; 2Department of Thoracic Surgery, Affiliated Hospital 6 of Nantong University, Yancheng Third People’s Hospital, Yancheng, 224000, People’s Republic of China; 3Medical School of Nantong University, Nantong, 226007, People’s Republic of China; 4Department of Anesthesiology, Affiliated Hospital 6 of Nantong University, Yancheng Third People’s Hospital, Yancheng, 224000, People’s Republic of China*These authors contributed equally to this workCorrespondence: Guopei Zhang, Email zhangicu@163.comObjective: To analyze the influencing factors contributing to the occurrence of delirium in patients within the Intensive Care Unit (ICU) and to construct a prediction model for delirium in critically ill patients, subsequently verifying its predictive value.Methods: A prospective study was conducted involving 641 patients admitted between January 2023 and June 2024. …”
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Impact of IL-17A Inhibitors on Serum Uric Acid Levels in Psoriatic Patients with Hyperuricemia: A Prospective Observational Study by Wu C, He C, Wang H, Wang W, Jin H

“…It also explored the risk factors for hyperuricemia in psoriatic patients and the effectiveness of IL-17A inhibitors for the skin lesions of psoriatic patients with hyperuricemia.Methods: Patients aged ≥ 18 years with moderate to severe plaque psoriasis along with concomitant hyperuricemia (defined as an SUA level > 416 μmol/L in men and > 357 μmol/L in women) at baseline were treated with either secukinumab or ixekizumab. …”
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Cow’s Milk Allergy and Associated Factors Among Children in Abha City, Saudi Arabia – A Retrospective Case Control Study by Alqurashi NK, Mahmood SE, Alsabaani A, Ahmad A, Khan MS, Shati AA

“…Therefore, this study was undertaken to determine the factors associated with CMA among children in Abha city and to explore the knowledge and practice regarding CMA among parents in Abha city.Methods: This retrospective one-year case control study was conducted amongst children with CMA (cases) and healthy children without CMA (controls) and their parents attending Abha Maternity and Children Hospital, Saudi Arabia. …”
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Effects of Acupuncture Combined with Conventional Rehabilitation Training for Patients with Post-Stroke Dysphagia: A Randomized Controlled Trial by Xu F, Zhang Y, Su X, Dai F, Ye Y, Ling M, Hu P, Cheng H

“…This study aimed to examine the effects of acupuncture combined with conventional rehabilitation training (CRT) on swallowing function, neurotransmitter levels, nutritional status, and swallowing-related quality of life in patients with PSD.Methods: Following screening, 90 patients with PSD were randomly assigned to either the intervention group (receiving acupuncture combined with CRT) or the control group (receiving CRT only). …”
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Low Impact Development-Based Drainage Design in Residential Areas: A Case Study of Mastrip Housing by Yangga Purnagusti, Entin Hidayah, Audiananti Meganandi Kartini

“…Therefore, infiltration LID methods can be considered to improve the effectiveness of reduction. …”
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Integrated Multi-Omics Analyses Reveal Innovative Diagnostic and Therapeutic Targets Associated with Atopic Dermatitis by Chen X, Cao B, Tan Z, Li X, Xu W, Liu Y, Gong F

“…Identifying novel, reliable biomarkers is crucial to enhance diagnostic accuracy, reduce healthcare costs, and aid in developing new treatments.Methods: Data from the Gene Expression Omnibus database were used to identify potential AD biomarkers through Weighted Gene Co-expression Network Analysis and machine-learning. …”
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Exploring the publication gap in pediatric randomized clinical trials: completed vs. uncompleted pediatric clinical trials by Katerina Nebeska, Katerina Nebeska, Lenka Souckova, Lenka Souckova, Lenka Souckova, Lenka Souckova, Radka Stepanova, Regina Demlova, Regina Demlova

“…The publication of RCTs’ results is equally crucial, yet not all completed RCTs share their findings, contributing to publication bias. …”
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Exploration of Epigenetic Mechanisms and Biomarkers Among Patients with Very-Late-Onset Schizophrenia-Like Psychosis by Gan Y, Yue W, Sun J, Yang D, Fang C, Zhou Z, Yin J, Zhou H

“…Yansha Gan,1,* Weihua Yue,2,* JiaoJiao Sun,1 DanTing Yang,1 ChunXia Fang,1 Zhenhe Zhou,1 JiaJun Yin,1 Hongliang Zhou3 1The Affiliated Mental Health Center of Jiangnan University, Wuxi, Jiangsu, 214151, People’s Republic of China; 2National Clinical Research Center for Mental Disorders, Peking University Sixth Hospital, Beijing, 100191, People’s Republic of China; 3Department of Psychology, The Affiliated Hospital of Jiangnan University, Wuxi City, Jiangsu, 214100, People’s Republic of China*These authors contributed equally to this workCorrespondence: JiaJun Yin, The Affiliated Mental Health Center of Jiangnan University, Wuxi, Jiangsu, 214151, People’s Republic of China, Email yinjiajun@jiangnan.edu.cn Hongliang Zhou, Department of Psychology, The Affiliated Hospital of Jiangnan University, No. 200, Huihe Road, Binhu District, Wuxi City, Jiangsu Province, People’s Republic of China, Email Hongliangzh2022@hotmail.comObjective: This study aimed to identify DNA methylation patterns associated with Very Late-Onset Schizophrenia-like Psychosis (VLOSLP) and to develop methylation-based biomarkers that differentiate VLOSLP from Schizophrenia (SCZ) and Alzheimer’s Disease (AD).Methods: We analyzed methylation microarray datasets (n = 1218) from SCZ and AD patients obtained from the GEO database. …”
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Association Between Vitamin A and D Status and the Risk of COVID-19 in the Elderly Population: A Single-Center Experience by Li T, Cui X, Li X, Yang J, Wang H, Yang J, Jin Z

“…Thus, the aim of this study was to explore the association between vitamin A and D status and the risk of COVID-19 in the elderly population.Methods: From April 1st to September 20th, 2023, 32 COVID-19 patients who tested positive for severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) infection through polymerase chain reaction (PCR) were enrolled in this study. …”
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The Effect of Eight Weeks of Motor Control Exercises and Myofascial Release on the Range of Motion of the Lumbar Spine and Disability in People with Non-Specific Chronic Low Back P... by S Jamali Brayjani, M.H Alizadeh, N Rahnama

“…Therefore, it is possible that both protocols can be suggested as a useful method for the rehabilitation of people with non-specific chronic low back pain.…”
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A Comparative Study of Esketamine-Propofol and Sufentanil-Propofol for Analgesia and Sedation During Breast Minimally Invasive Rotary Resection with Local Anesthesia: A Randomized... by Li N, Qi X, Bao J, Gu Y, Zhou X, Wang T, Jiang N, Wang Y, Ye Q

“…This study aims to compare the safety and efficacy of esketamine versus sufentanil as adjuncts to propofol for analgesia and sedation during breast MIRR.Patients and Methods: A total of 90 patients undergoing elective breast MIRR were randomly assigned to receive either sufentanil-propofol or esketamine-propofol for analgesia and sedation. …”
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The Mediating Effects of Self-Acceptance and Self-Evaluation on Mindfulness and Benefit -Finding in a Sample of Chinese Systemic Lupus Erythematous Patients by Xu F, Tong X, Niu Y, Lin Q, Yao A, Yang F, Li L

“…Through structural equation models, we examined the mediating role of self-acceptance and self-evaluation between mindfulness and benefit-finding.Patients and Methods: We used a convenient sampling method to investigate the demographics characteristics, mindfulness, self-acceptance, and benefit-finding of 319 SLE patients who were admitted to the rheumatology and immunology departments of tertiary, and Grade-A hospitals from December 2019 to December 2020.Results: Educational Levels, age, presence of other diseases besides SLE, medical expense payment method can affect mindfulness, and benefit-finding in SLE patients (p< 0.05), monthly salary can also influence mindfulness (p< 0.05), marital status also have impact on benefit-finding (p< 0.05). …”
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Impact of Echinococcus granulosus Cyst Fluid on the Phenotypic Dynamics and Degranulation of RBL-2H3 Mast Cells by Yue Z, Zhou JR, Wang CS, Pu XL, Parehati G, Cao LW, Bayina B, Ye JR

“…Zhen Yue,1,2,* Jing-Ru Zhou,3,* Chun-Sheng Wang,1 Xue-Li Pu,1 Guligeiya Parehati,1 Li-Wei Cao,1 Batesurong Bayina,1 Jian-Rong Ye1 1Department of Anesthesiology, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, 830054, People’s Republic of China; 2Department of Anesthesiology, Changji People’s Hospital, Changji, 831100, People’s Republic of China; 3Department of Anesthesiology, The Sixth Affiliated Hospital of Xinjiang Medical University, Urumqi, 830063, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jian-Rong Ye, Department of Anesthesiology, The First Affiliated Hospital of Xinjiang Medical University, No. 137, Liyushan South Road, Urumqi, 830054, People’s Republic of China, Tel +86 18999938777, Email ywjianrongym@126.comObjective: This study aimed to evaluate the effects of Echinococcus granulosus cyst fluid (EgCF) on the phenotypic characteristics and degranulation activity of mast cells during echinococcosis-associated hypersensitivity reactions, using the RBL-2H3 rat basophilic leukemia cell line as an in vitro model.Methods: The cytotoxic effects of EgCF on RBL-2H3 cells were assessed using the Cell Counting Kit-8 assay. …”
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Prognostic Value of Apolipoprotein E in Predicting One-year Mortality in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease by Li Y, Wu Q, Li Z, Xiao Y, Wei L

“…This study sought to investigate the correlation between the levels of ApoE and all-cause mortality over one year in individuals who are diagnosed with acute exacerbations of chronic obstructive pulmonary disease (AECOPD).Methods: In this study, we checked serum ApoE concentrations of AECOPD patients on admission and collected the patients’ laboratory and clinical information. …”
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Evaluation of Streptococcus faecalis, Clostridium butyricum, Bacillus mesentericus, Lactobacillus sporogenes, Saccharomyces Boulardi multistrain probiotic formulation in acute gast... by Bhavna Darshan Patel, Girish Kulkarni, Swagata Chowdhuri, Animesh Arya, Kaithayil Mammen John, Ashwini Suyog Patki Doshi, Rathish Nair, Krishnaprasad Korukonda

“…Probiotics were prescribed to 99.07% of patients, with an equal proportion achieving diarrhea resolution. Stool frequency significantly decreased by 67.94% (p < 0.0001), and Oral Rehydration Solution (ORS) use declined from 54.21% at baseline to zero by Day 7. …”
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Exogenous GABA Alleviates Tourette Syndrome-Like Behavior in Sprague-Dawley Rats by Altering Gut Microbiota and Striatum Metabolism by Xu Y, Li LN, He XJ, Wang S, Li X, Feng H, Zhang HF, Song L, Shi HS, Tian XY

“…Ying Xu,1,2 Li-Na Li,1,2,&ast; Xiang-Jun He,1,2 Shuang Wang,2 Xincheng Li,2 Hao Feng,2 Hui-Feng Zhang,1 Li Song,2 Hai-Shui Shi,2– 4,&ast; Xiao-Yu Tian1,&ast; 1The Department of Pediatrics, The Second Hospital of Hebei Medical University, Shijiazhuang, 050000, People’s Republic of China; 2Neuroscience Research Center, Institute of Medical and Health Science, Hebei Medical University, Shijiazhuang, 050017, People’s Republic of China; 3Nursing School, Hebei Medical University, Shijiazhuang, 050031, People’s Republic of China; 4Hebei Key laboratory of Neurophysiology, Hebei Medicinal University, Shijiazhuang, 050017, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Xiao-Yu Tian, The Department of Pediatrics, The Second Hospital of Hebei Medical University, Shijiazhuang, 050000, People’s Republic of China, Email janetian@hebmu.edu.cnContext: Tourette syndrome (TS) is a common chronic neuropsychiatric disorder with a prevalence of approximately 1% in children and adolescents. …”
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Effectiveness and Safety of Acupuncture as an Adjunctive Therapy for Post-Stroke Depression: An Overview of Systematic Reviews by Liu X, Zhu F, Zhang JL, He ZX, Yin S, Wu RH, He YY, Zeng F

“…Acupuncture as an adjuvant therapy shows promise, though current systematic reviews exhibit significant discrepancies in effectiveness/safety evidence with insufficient methodological rigor.Purpose: To evaluate systematic reviews assessing acupuncture as an adjuvant therapy for PSD.Methods: Electronic searches were conducted across eight databases from their inception to March 2024. …”
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