Vaccine-induced T cell responses correlate with reduced risk of severe COVID-19 in a placebo-controlled efficacy trialResearch in context by Nina Hertoghs, Sanne Roels, Matthias Brückner, Jerald Sadoff, Barbara L. Banbury, Nicholas K. Akers, Bryan Howie, Harlan S. Robins, Griet A. van Roey, Jeroen T.B.M. Tolboom, Veronica V. Rezelj, Jenny Hendriks, Hanneke Schuitemaker, Daniel J. Stieh, Mathieu Le Gars

“…The purpose of this study is to investigate whether signatures of the T-cell response contribute to protection against (severe) COVID-19. Methods: T cell receptor (TCR) sequencing was conducted using pre-vaccination and 29 days post-vaccination PAXgene samples from 396 participants in the phase 3 efficacy trial, ENSEMBLE. …”
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Tacrolimus concentration/dose ratio as a therapeutic drug monitoring strategy: The influence of gender and comedication by Rančić Nemanja, Dragojević-Simić Viktorija, Vavić Neven, Kovačević Aleksandra, Šegrt Zoran, Drašković-Pavlović Biljana, Mikov Momir

“…Methods. This prospective case series study included 54 patients, in which the unit of monitoring was outpatient examination (1,872) of the renal transplant patients. …”
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Machine learning-based ultrasound radiomics for predicting risk of recurrence in breast cancer by Wei Fan, Hao Cui, Xiaoxue Liu, Xudong Zhang, Xinran Fang, Junjia Wang, Zihao Qin, Xiuhua Yang, Jiawei Tian, Lei Zhang

“…PurposeTo develop a radiomics model based on ultrasound images for predicting risk of recurrence in breast cancer patients.MethodsIn this retrospective study, 420 patients with pathologically confirmed breast cancer were included, randomly divided into training (70%) and test (30%) sets, with an independent external validation cohort of 90 patients. …”
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Evaluation of physicians’ opioid prescribing practices, attitudes, and interactions with other healthcare professionals in optimizing opioid prescribing in Pakistan by Hafsa Arshad, Hafsa Arshad, Hafsa Arshad, Ali Hassan Gillani, Ali Hassan Gillani, Ali Hassan Gillani, Muhammad Arshed, Yu Fang, Yu Fang, Yu Fang

“…More than half of the respondents were men, accounting for 58.8% of the total, and an equal proportion of respondents, 56.9%, were from government hospitals. …”
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Anti-SARS-CoV-2 antibody responses in convalescent plasma donors with varying severity of COVID-19 illness by Grujić Jasmina, Bujandrić Nevenka, Budakov-Obradović Zorana, Savić Nebojša, Dolinaj Vladimir

“…During the study, 651 apheresis plasma units were collected and divided into two equal doses. Plasma was donated by 311 COVID- 19 convalescents, including 208 (66.9%) men and 103 (33.1%) women. …”
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Association of preclinical blood glucose with hospitalization rate and in‐hospital mortality: A single‐center retrospective cohort study by Simon Kloock, Danilo Skudelny, Peter Kranke, Gülmisal Güder, Dirk Weismann, Martin Fassnacht, Christian G. Ziegler, Ulrich Dischinger

“…Patients with a PBG ≥140 mg/dL (G1, n = 394, equal to 7.8 mmol/L) were compared with patients with a PBG <140 mg/dL (G2, n = 576). …”
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Patient-reported outcomes three months after treatment of metacarpal and phalangeal fractures or dislocations: a multicentre snapshot study by Louise E. M. de Haas, Veronique A. P. van de Lücht, Bastiaan T. van Hoorn, Dorien A. Salentijn, Rolf H. H. Groenwold, Niels W. L. Schep, Mark van Heijl, Snapshot Hand Fractures Collaborative Study Group members

“…After nonoperative treatment, 104/398 patients (26%) reached a MHQ score equal to or better than the normative MHQ score, ranging between 11% (1/9) and 42% (13/31) among the nine most common injury types. …”
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Longitudinal study of family formation in 892 women and 193 men 8 years after visiting the Fertility Assessment and Counselling (FAC) clinic by Randi Sylvest, Ida Vittrup, Ditte Vassard, Marte Saupstad, Søren Ziebe, Elisabeth Larsen, Helene Westring Hvidman, Kathrine Birch Petersen, Henriette S. Nielsen, Lone Schmidt, Anja Pinborg

“…The mean age for the subgroup of 892 women who responded at 8 years follow‐up was 32.6 (±SD 4.4) years at baseline which was equal to the total cohort of 2635 women at baseline (32.7 (±SD 4.7) years). …”
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The impact of training on communication quality during interpreter‐mediated cognitive assessments: Study protocol for a randomized controlled trial by Bianca Brijnath, Erika Gonzalez, Jim Hlavac, Joanne Enticott, Robyn Woodward‐Kron, Dina LoGiudice, Lee‐Fay Low, Josefine Antoniades, Jenni White, Kerry Hwang, Xiaoping Lin, Andrew Simon Gilbert

“…We aim to enroll 150 interpreters, and allocate them to equal parallel groups. The intervention group will receive access to the MINDSET training, which comprises 4 hours of resources covering five domains: dementia knowledge, cross‐cultural communication, briefings and debriefings, interpreting skills, and interpreting ethics. …”
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Observation of the Effects of Infrapatellar Fat Pad Excision on the Inflammatory Progression of Knee Osteoarthritis in Mice by Li Y, Lu P, Yao H, Yang S, Tu B, Kong L, Ning R

“…Excision of the IFP is considered a potential therapeutic approach to reduce inflammation and slow disease progression.Methods: A mouse model of KOA was used to evaluate the impact of IFP excision on inflammation. …”
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Risk Factors and Diagnostic Model Construction of Chronic Pain with Cognitive Impairment by Zhang C, Su Y, Zeng X, Zhu X, Gao R, Liu W, Du R, Chen C, Liu J

“…This study aimed to explore the correlation between complete blood count parameters and CP-related CI to establish a risk diagnostic model for the early detection of CP-related CI.Methods: This cross-sectional study was conducted at West China Hospital, Sichuan University. …”
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Effects of Suryanamaskara and Sheetali Pranayama on College Students Aggression: A Prospective Interventional Study by Youganjaly Mehra, Malika Sharma, Kalpana Sharma

“…A comparative analysis revealed equivalent changes in aggression levels between the two groups, indicating that both yogic interventions were equally effective in reducing aggression in college students.…”
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Challenges and inequalities in the management of financing the tasks of local government units: a critical analysis by Arkadiusz Ciach

“…Research methods 1. Analysis of empirical data: Examination of data from local government units (LGUs) between 2019 and 2023. 2. …”
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Alopecia Secondary to Hyaluronic Acid Injection: A Case Report and Literature Review by Jia L, Xiong J, Zhao C, Jiang H, Li Y

“…Lingling Jia,1,2,&amp;ast; Jiachao Xiong,1,2,&amp;ast; Changjiang Zhao,1,2 Hua Jiang,1,2 Yufei Li1,2 1Department of Plastic Surgery, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai, 200120, People’s Republic of China; 2Medical College, Tongji University, Shanghai, 200331, People’s Republic of China&amp;ast;These authors contributed equally to this workCorrespondence: Hua Jiang, Email dosjh@126.com Yufei Li, Email lufylee@hotmail.comBackground: Hyaluronic acid injections, commonly used for anti-aging purposes, carry potential risks, including transient or permanent alopecia, a complication not yet fully characterized. …”
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Analysis of Consistency Between Forensic Psychiatric Evaluation Diagnosis and Previous Clinical Psychiatric Diagnosis: A Retrospective Study by Li M, Cao Y, Wang X, Li L, Wu C, Yi X, Wang K, Zheng H, Liu Y, Xiong Z, Gong J, Ji Q

“…Therefore, the purpose of this study is to systematically analyze the consistency between forensic psychiatric identification diagnosis (referred to as identification diagnosis) and previous psychiatric diagnosis (referred to as previous diagnosis) in criminal cases.Methods: Using a retrospective study design, 78 criminal cases evaluated as having no mental illness by the Forensic Evaluation Department of Wuhan Mental Health Center in 2021– 2022 were selected as research subjects. …”
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Microscale bone interlocking enhances osseointegration strength on the rough surface of 3D-printed titanium implants: experimental and finite element analysis by Tianyu Shu, Haoyu Shi, Meng Li, Yu-Chia Lin, Ang Li, Dandan Pei

“…Histological osseointegration assessments revealed equal levels of SLM and CNC-SLA implants at weeks 1, 2, and 8. …”
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Predictive Value of Preoperative Hypersensitive C-Reactive Protein in the Incidence of Postoperative Cognitive Impairment in Valvular Disease Patients: A Retrospective Study by Zhao A, Peng Y, Lin L, Chen L, Lin Y

“…This study investigated the potential of pre-operative hypersensitive C-reactive protein (Hs-CRP) as a prognostic indicator of POCD in valvular disease (VHD).Methods: This study retrospectively analyzed 372 VHD patients admitted to the Department of Cardiac Surgery, Fujian Medical University Union Hospital from January 2024 to July 2024. …”
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Clinical Study on Prevention of Irinotecan-Induced Delayed-Onset Diarrhea by Hot Ironing with Moxa Salt Packet on Tianshu and Shangjuxu by Xianghong Lai, Anmei Wang

“…They were equally divided into study group (n = 60) and control group (n = 60) according to whether they were treated with hot ironing with moxa salt packs or not. …”
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Analyzing Pain Patterns in Stroke Survivors in Outpatient Clinics: A Retrospective, Cross-Sectional, Observational Study by Dishman D, Gonzalez C, Thomas TS, Indupuru HK, Kim S, Green C, Sharrief A, Savitz SI

“…Multivariable analysis was performed using the logistic regression method.Results: Of the 442 subjects, 58% (N=258) reported pain, with 56% experiencing multiple pain types. …”
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The Impact of Suboccipital Muscle Release on Pain and Range of Motion in the Cervical Spine of Young Adults by Tymoteusz Kaczmarek, Aleksandra Truszczyńska-Baszak

“…On average, the level equalled 4.25 0.76 (after 4 weeks). In the study group, the range of flexion motion was, on average, 3.24 1.00 cm, extension, mean 6.90 1.14 cm, lateral flexion to the left, on avg. 4.76 0.62, to the right on avg. 4.90 1.04 cm, left rotation on avg. 8.43 0.81, and right rotation on avg., 8.19 1.08 cm. …”
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