Suggested Topics within your search.
Suggested Topics within your search.
-
6881
Apoptotic Vesicles Attenuate Acute Lung Injury via CD73-Mediated Inhibition of Platelet Activation and NETosis
Published 2025-01-01“…In this study, our aim was to investigate the therapeutic effects and underlying mechanisms of apoVs in ALI.Methods: ALI was induced in mice through intratracheal instillation of lipopolysaccharide (LPS). …”
Get full text
Article -
6882
Cholera in conflict: outbreak analysis and response lessons from Gadaref state, Sudan (2023–2024)
Published 2025-03-01“…The mean age was 16.8 (SD, 15.8) with an equal gender distribution. The case fatality ratio was 2.4% and the overall attack (AR) rate was 7.38 cases per 10,000 population, with the highest in Medeinat Gadaref locality (21.07/10,000). …”
Get full text
Article -
6883
Effect of a Narrative-Based Online Course Aimed at Reducing Stigma Toward Transgender Children and Adolescents: Longitudinal Observational Study
Published 2025-01-01“…ObjectiveThis study aims to evaluate the impact of an animated online course, rooted in authentic, personal narratives, on course participants’ stigma toward transgender youth. MethodsThe online course was offered free of charge on Coursera and contained 19 teaching videos (3-7 minutes each), intermittent practice quizzes, and discussion prompts. …”
Get full text
Article -
6884
Hsa_circ_0078767 Enhances Osteosarcoma Chemoresistance to Doxorubicin Through the Regulation of the miR-188-3p/GPX4 Axis
Published 2024-11-01“…This analysis sought to examine hsa_circ_0078767 as a mediator of doxorubicin (DOX) resistance in OS.Methods: Levels of hsa_circ_0078767, miR-188-3p, and glutathione peroxidase 4 (GPX4) in OS clinical tissue samples and cell lines were evaluated by quantitative polymerase chain reaction (qPCR) and Western blotting. …”
Get full text
Article -
6885
Evaluation of the Shear Bond Strength of Orthodontic Adhesive Incorporated with Titanium Dioxide Nanoparticle: An In-vitro Study
Published 2025-02-01“…Study included 60 samples of extracted human maxillary first premolar teeth. The samples were equally divided into two groups. In group 1, brackets were bonded with conventional composite, and in group 2, brackets were bonded with TiO2 nanocomposite. …”
Get full text
Article -
6886
A Mortality Risk Prediction Model for Septic Shock in Patients Aged ≥50: Role of Norepinephrine Index and Procalcitonin
Published 2025-06-01“…This study aimed to develop and validate a predictive model using norepinephrine index (NEI)—a novel biomarker defined as the norepinephrine dose administered within the first 24 hours of ICU admission divided by BMI and 24 hours—and procalcitonin (PCT) to improve risk stratification and clinical decision-making.Methods: A retrospective cohort of 94 patients aged ≥ 50 years with septic shock was analyzed. …”
Get full text
Article -
6887
Pregnancy in adolescence and adverse neonatal outcomes in Ecuadorian mestizo newborns
Published 2020-04-01“…Background: To establish the association between pregnancy in early and middle adolescence and adverse neonatal outcomes in Ecuadorian mestizo newborns. Methods: Study design: epidemiological, observational/descriptive, and cross-sectional. …”
Get full text
Article -
6888
Hyaluronic Acid is Associated with Severity and Prognosis in Patients with Community-Acquired Pneumonia
Published 2024-12-01“…This study investigated the association of HA with severity and prognosis in hospitalized patients with community-acquired pneumonia (CAP).Patients and Methods: We analyzed the differences of HA levels in different groups. …”
Get full text
Article -
6889
Effects of Specific RAMP Protocol Phase on Change of Direction Speed of Police Students
Published 2024-10-01“…., tactical athletes). <b>Methods:</b> A longitudinal design with two experimental and one control group was employed. …”
Get full text
Article -
6890
Characteristics of the microbiota in patients with various clinical phenotypes of occupational COPD and chronic bronchitis
Published 2025-03-01“…Antimicrobial susceptibility was determined by disk diffusion method. Results. The common characteristics of the microbiota in COPD patients with both phenotypes were: the predominance of the Firmicutes type, equal bacterial load (p = 0.48), the absence of protective commensals and microorganisms typical for COPD patients (Moraxella catarrhalis). …”
Get full text
Article -
6891
Micro-Electro Nanofibrous Dressings Based on PVDF-AgNPs as Wound Healing Materials to Promote Healing in Active Areas
Published 2025-01-01“…By designing a micro-electro-Nanofiber dressing composed of piezoelectric polyvinylidene fluoride (PVDF) integrated with antimicrobial silver nanoparticles (AgNPs), this research aims to address the dual challenges of promoting effective wound healing and maintaining joint mobility.Methods: Herein, we developed a novel micro-electro-Nanofiber dressing using electrospinning technology, incorporating polyvinylidene fluoride (PVDF) with silver nanoparticles (AgNPs). …”
Get full text
Article -
6892
Theranostic Applications of Taurine-Derived Carbon Dots in Colorectal Cancer: Ferroptosis Induction and Multifaceted Antitumor Mechanisms
Published 2025-06-01“…Rongrong Zhang,1,&ast; Shuting Lan,1,&ast; Mengxuan Jia,1,&ast; Fangyuan Liu,1 Mengqi Wang,2 Qin Jin,3 Liya Su,1 Gang Liu1 1Clinical Medicine Research Center, Affiliated Hospital of Inner Mongolia Medical University, Hohhot, Inner Mongolia, People’s Republic of China; 2College of Life Science and Oceanography, Weifang University, Weifang, Shandong, People’s Republic of China; 3Department of Pathology, Affiliated Hospital of Nantong University, Nantong, Jiangsu, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Gang Liu, Email 20190043@immu.edu.cnIntroduction: The theranostic potential of taurine-derived carbon dots (Tau/CDs) in colorectal cancer (CRC) remains largely unexplored, despite their promising physicochemical and biological properties.Methods: In this study, Tau/CDs were synthesized via a microwave-assisted irradiation method, employing citric acid as the carbon source, urea as the nitrogen source, and taurine (Tau) as the dopant. …”
Get full text
Article -
6893
A Nomogram for Predicting the Risk of Death in Patients with Prolonged Hospital Stays in Internal Medicine Wards: A Retrospective Study
Published 2025-04-01“…This study aimed to investigate the relationship between PLOS and mortality among patients hospitalized in internal medicine wards and to develop a nomogram to predict the risk of death in this patient population.Methods: This retrospective study included patients hospitalized for more than 30 days in internal medicine wards between January 1, 2022, and December 31, 2022. …”
Get full text
Article -
6894
Radiological and Clinical Presentation of Interstitial Lung Disease in Patients with Concomitant Psoriasis: A Cross-sectional Study
Published 2025-04-01“…The median age was 51.5 years (range 25-65), males and females were equally affected. The median time for the development of respiratory symptoms from the diagnosis of psoriasis was 24.5 months (range 6-60). …”
Get full text
Article -
6895
Effects of pre-storage leukoreduction on erythrocyte concentrates and performance of newer generation leuko-filters at a tertiary care oncology hospital in Western India
Published 2025-06-01“…All EC units demonstrated a 99.99% leukocyte log reduction, with both filters showing equal efficacy. Post-leukoreduction haemoglobin concentrations were lower than the pre-leukoreduction for all units (p 0.001). …”
Get full text
Article -
6896
Utility of the ASPECT Score for Predicting Intracranial Hemorrhage Following Intravenous Thrombolysis in Patients with Suspected MCA Infarction: Insights from the Northern Thai Str...
Published 2024-11-01“…This study aimed to determine the relationship between ASPECTS and thrombolysis-associated outcomes, focusing on symptomatic (sICH) and asymptomatic (aICH) ICH.Patients and methods: AIS patients with middle cerebral artery (MCA) territory treated with thrombolysis were enrolled. …”
Get full text
Article -
6897
The Predictors of High Dietary Salt Intake among Hypertensive Patients in Iran
Published 2020-01-01“…In all 205 patients, 62.9% female, 40.5% aged over 60 years, and 53.7% with low or moderate socioeconomic status, 49.3% body mass index (BMI) 30 kg/m2 and above, 10.2% of the patients had systolic/diastolic equal and above (≥) 40/90 mmHg, participated in the study. …”
Get full text
Article -
6898
Effectiveness of Onosma dichroanthum Boiss Combined Ointment on Episiotomy Healing and Pain in Primiparous Women: A Randomized, Clinical Trial
Published 2025-06-01“…Equally, the control group received a placebo following the same schedule. …”
Get full text
Article -
6899
BODY MASS INDEX IN ISCHEMIC HEART DISEASE AND SHORT-TERM OUTCOMES OF CORONARY BYPASS GRAFTING
Published 2015-11-01“…The groups were equal by clinical data and anamnesis, laboratory and instrumental data. also we evaluated the prevalence of post operation complications and perioperational mortality. …”
Get full text
Article -
6900
A Bidirectional Mendelian Randomization Study of Causal Relationships Between Migraine and White-Matter Structural Connectivity
Published 2025-07-01“…Dan Tong,1,2,&ast; Xinyue Zhang,1,2,&ast; Zhiyong Xiao,1,3,&ast; Supattra Taothong,1,2 Prapawee Teeravarunyou,1,2 Wanxia Wu,1,2 Sai Wu,1,2 Nuo Chen,1,2 Siyuan Tao,1,2 Jun Zhou,1,2 Qian Song,4 Fanrong Liang,1,2 Zhengjie Li1,2,4 On behalf of International Headache Genetics Consortium (IHGC)1Acupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, People’s Republic of China; 2Key Laboratory of Acupuncture for Senile Disease (Chengdu University of TCM), Ministry of Education, Chengdu, Sichuan, People’s Republic of China; 3Sichuan Jinxin Xinan Women’s & Children’s Hospital (Bisheng), Chengdu, People’s Republic of China; 4National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, Tianjin, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Zhengjie Li, Email lzjbenjamin@163.comObjective: This study aims to investigate the potential causal relationship between migraine and white matter (WM) structural connectivity using genetic data and the Mendelian randomization (MR) analyses method.Methods: Genome-wide association study (GWAS) summary statistics for migraine (48,975 cases/540,381 controls) and 206 WM structural connectivity related imaging-derived phenotypes (IDPs) (26,333 samples) were collected. …”
Get full text
Article