Mechanism of Mongolian Medicine Batri-7 on Salmonella Enteritis by Yang D, Chen S, Borijihan H, Aoqier A, Sarula S, Siqin S, Manda M, Temuqile T, Baigude H

“…Simultaneously, the Minimum Inhibitory Concentration of BT-7 was evaluated against bacterial by microbroth dilution method, BT-7 regulation of Salmonella typhimurium gene was performed by RNA-Seq methods and verified by qRT-PCR.Results: In the LC-MS/MS assay, negative and positive-ion modes are identified for 511 and 699 compounds from BT-7, respectively. …”
Get full text

Knowledge, Attitude and Practice towards Medical Research among Interns and Postgraduate Students of a Government Medical College: A Cross-sectional Study by Sukanya Badami, Vasundara S Gayakwad, Mahesh Baragundi, Srinivasa Arer

“…The latest information on skills of scientific principles and methods is essential for the conduct of research. …”
Get full text

Comparative Assessment of Microleakage in Nanohybrid Composite Using Two Different Layering Techniques for Class V Cavities: An In-vitro Study by R Aswathy Raj, Ida De Noronha De Ataide, Rajan Lambor

“…Introduction: Numerous methods for composite restoration have been developed to mitigate the impacts of polymerisation shrinkage. …”
Get full text

The Safety and Effectiveness of Multi-Segment Cortical Bone Trajectory Screws in Adult Degenerative Scoliosis with Stenosis Among the Elderly: Minimum 5-year Follow-up Study by Wang J, Ding Z, Liu Y, Hai Y

“…Jie Wang,1,* Zihao Ding,1,* Yuzeng Liu,1 Yong Hai1– 4 1Department of Orthopedic Surgery, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, 100020, People’s Republic of China; 2Joint Laboratory for Research & Treatment of Spinal Cord Injury in Spinal Deformity, Capital Medical University, Beijing, 100069, People’s Republic of China; 3Laboratory for Clinical Medicine, Capital Medical University, Beijing, 100069, People’s Republic of China; 4Clinical Center for Spinal Deformity, Capital Medical University, Beijing, 100069, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yuzeng Liu, Email beijingspine2010@163.com Yong Hai, Email yong.hai@ccmu.edu.cnPurpose: To evaluate the long-term efficacy and safety of multi-segment cortical bone trajectory screws for treating mild adult degenerative scoliosis with stenosis among the elderly.Patients and Methods: From January 2018 to December 2019, a total of 41 patients of mild adult degenerative scoliosis with stenosis underwent posterior lumbar decompression, bone graft fusion, and internal fixation, which were retrospectively divided into pedicle screw (PS) group and cortical bone trajectory (CBT) screw group according to different internal fixation methods. …”
Get full text

Recurrent Rhegmatogenous Retinal Detachment: Characteristics, Risk Factors, and Outcomes by Aleshawi A, Al-Dwairi R, Saleh OA, Adi S, Al Beiruti S, Alasheh A, Alsaadi MA, Ouda ZH, Allouh MZ

“…Using proper statistical methods, the results were generated.Results: The study comprised 348 patients with primary RRD, of whom 44.5% had a previous ocular surgical history. …”
Get full text

Implementation and Strategy in Developmental Care Practice in Infants with Congenital Heart Disease in Intensive Care Unit: Scoping Review by Rhamelani P, Rakhmawati W

“…The strategies in implementing the intervention include aspects of health workers (experience, training, and licensing); aspects of intervention protocols; and aspects of intervention methods and models (socialization, strict supervision, and the Plan-Do-Study-Act (PDSA) model). …”
Get full text

The influence of tactical models of team play on the dynamics of collective ball control indicators in football by Pavlo Perepelytsia, Volodymyr Perevoznyk, Volodymyr Paievskyi, Anatoliy Abdula, Irina Pomeshchikova, Betrix Yachsie

“…The total number of subjects was 22 players, who were distributed according to equal indicators of physical and technical fitness into two groups, control and experimental. …”
Get full text

Deep learning based bio-metric authentication system using a high temporal/frequency resolution transform by Sajjad Maleki Lonbar, Akram Beigi, Nasour Bagheri, Nasour Bagheri, Pedro Peris-Lopez, Carmen Camara

“…For the NSRDB dataset, the model achieved an accuracy of 99.3% and an Equal Error Rate (EER) of 0.8%. Similarly, for the MITDB dataset, the model demonstrated an accuracy of 99.004% and an EER of 0.8%. …”
Get full text

Professional-Facing Digital Health Technology for the Care of Patients With Chronic Pain: Scoping Review by Haruno McCartney, Ashleigh Main, Natalie McFayden Weir, Harleen Kaur Rai, Maryam Ibrar, Roma Maguire

“…MethodsDatabases, including MEDLINE, Embase, CINAHL, PsycINFO, and Inspec, were searched using comprehensive search strategies. …”
Get full text

EVALUATION OF PERIODONTAL TISSUES CONDITION IN CHILDREN WITH BLOOD COAGULABILITY PATHOLOGY by M. A. Gavrilenko

“…Hygiene index value was determined according to Fedorov and Volodkina, PMA index (papillary-marginal-alveolar index) was determined by standard methods. Visual presence of inflammation clinical signs and periodontal tissue condition was determined in each group. …”
Get full text

Machine Learning and Interpretability Study for Predicting 30-Day Unplanned Readmission Risk of Schizophrenia: A Retrospective Study by Tan Y, Chen G, Wang S, Zhan X, Cheng R, Qiao L, Zhang Z, Liu Y

“…Yuting Tan,1,2,* Guiling Chen,1,3,* Shuge Wang,1 Xingxin Zhan,4 Rong Cheng,1,2 Linru Qiao,1 Zhixia Zhang,1 Yaping Liu1 1Department of Nursing, Tianyou Hospital Affiliated to Wuhan University of Science and Technology, Wuhan, Hubei, People’s Republic of China; 2Institute of Nursing Research, Hubei Province Key Laboratory of Occupational Hazard Identification and Control, School of Medicine,Wuhan University of Science and Technology, Wuhan, Hubei, People’s Republic of China; 3Department of Psychiatry, Tianyou Hospital Affiliated to Wuhan University of Science and Technology, Wuhan, Hubei, People’s Republic of China; 4School of Public Health, Xinyu University, Xinyu, Jiangxi, People’s Republic of China*These authors contributed equally to this workCorrespondence: Zhixia Zhang; Yaping Liu, Department of Nursing, Tianyou Hospital Affiliated to Wuhan University of Science and Technology, Wuhan, Hubei, People’s Republic of China, Tel +8613476805827, Email zzx13476805827@126.com; bzmulyp@126.comPurpose: To build a 30-day unplanned readmission (UPR) risk prediction model based on machine learning (ML) and SHapley Additive exPlanation (SHAP) with data obtained from the electronic medical records (EMRs) of patients with schizophrenia, so as to provide support for early intervention in clinical treatment.Patients and Methods: This retrospective study selected 1,123 patients with schizophrenia who were hospitalized at least once from January 1, 2021 to June 30, 2024 according to their EMRs. …”
Get full text

Emerging Implications of Serum Resolvin D2 as a Biochemical Marker for Severity Assessment and Prognosis Prediction Following Moderate-Severe Traumatic Brain Injury: A Prospective... by Zong H, Zong Y, Li J, Zhao S, Wu W, Chen R, Zhao G, Li Z

“…This study aimed to ascertain the potential of serum RvD2 level as a prognostic predictor of moderate-to-severe traumatic brain injury (msTBI).Methods: In this prospective cohort study, serum RvD2 levels were measured in 136 patients with msTBI and 100 healthy controls. …”
Get full text

Research Trends and Developments in Nanomaterials for Rheumatoid Arthritis: A Comprehensive Bibliometric Analysis by Jia X, He L, Chang Y, Li J, Wang J, Zhang X, Guo J

“…However, the existing diagnosis and treatment methods are limited by factors such as misdiagnosis, missed diagnosis, and toxic side effects. …”
Get full text

Factor Analysis of the Effect of Hepatitis B-Related Liver Cancer Treatment Efficacy by Liu SW, Zhou Y, Feng XY, Hai L, Ma WL, Ma LN, Ding XC, Luo X

“…This study analyzes the clinical factors related to the overall survival (OS) and progression-free survival (PFS) of patients with hepatitis B-related hepatocellular carcinoma (HCC) treated with DEB-TACE to provide reference data for individualized treatment.Methods: In this retrospective study, 128 patients with hepatitis B-related primary liver cancer who received DEB-TACE treatment and being followed up (range of follow-up: 4– 39 months) were included. …”
Get full text

Effect of two different digital construction techniques of mandibular implant-assisted overdentures on peri-implant bone loss and posterior ridge resorption: a 3-year prospective r... by Nermeen El Sayed El Khamisy, Radwa M.K. Emera, Thuraya Maher Elmanci, Marwa Ahmed Aboelez

“…So, this study aimed to investigate the effect of two different digital construction techniques of implant-assisted overdentures on peri-implant and posterior mandibular bone resorptions by CBCT. Materials and methods Twenty patients who received mandibular overdenture constructed by different construction techniques were classified equally and randomly into two groups (n = 10 per group): Group M: received milled mandibular overdenture opposed by maxillary complete denture. …”
Get full text

Evaluating the Potential of Prevalent New User Design as an Alternative When New User Design is Impractical by Koinuma T, Akazawa M

“…This approach helps researchers study real-world medication risks more effectively, offering an alternative to traditional methods.Keywords: propensity scores, claims data, observational study, pharmacoepidemiology…”
Get full text

Network Pharmacology and Experimental Validation of the Effects of Shenling Baizhu San, Quzhi Ruangan Fang and Gexia Zhuyu Tang on the Intestinal Flora of Rats with NAFLD by Guo J, Shi A, Sun Y, Zhang S, Feng X, Chen Y, Yao Z

“…Jia Guo,1,2,* Anhua Shi,1,3,4,* Yanhong Sun,1 Shunzhen Zhang,1 Xiaoyi Feng,1,3,4 Yifan Chen,1 Zheng Yao1,3,4 1School of Basic Medical Sciences, Yunnan University of Chinese Medicine, Kunming, Yunnan, 650500, People’s Republic of China; 2Dongtai Hospital of Traditional Chinese Medicine, Dongtai, Jiangsu, 224200, People’s Republic of China; 3The Key Laboratory of Microcosmic Syndrome Differentiation, Education Department of Yunnan, Yunnan University of Chinese Medicine, Kunming, Yunnan, 650500, People’s Republic of China; 4Yunnan Key Laboratory of Integrated Traditional Chinese and Western Medicine for Chronic Disease in Prevention and Treatment, Yunnan University of Chinese Medicine, Kunming, Yunnan, 650500, People’s Republic of China*These authors contributed equally to this workCorrespondence: Zheng Yao, School of Basic Medical Sciences, Yunnan University of Chinese Medicine, Kunming, Yunnan, 650500, People’s Republic of China, Tel +8618908719365, Email YaoYNUCM@163.comObjective: In this study, we investigated the effect of Shenling Baizhu San(SLBZS), Quzhi Ruangan Fang(QZRGF) and Gexia Zhuyu Tang(GXZYT) on the intestinal flora of NAFLD rats through network pharmacology and experimental validation.Materials and Methods: Protein-protein interaction, Gene Ontology (GO), and molecular docking were performed. …”
Get full text

EVALUATION OF PERIODONTAL TISSUES CONDITION IN CHILDREN WITH BLOOD COAGULABILITY PATHOLOGY by M. A. Gavrilenko

“…Hygiene index value was determined according to Fedorov and Volodkina, PMA index (papillary-marginal-alveolar index) was determined by standard methods. Visual presence of inflammation clinical signs and periodontal tissue condition was determined in each group. …”
Get full text

A Retrospective Machine Learning Analysis to Predict 3-Month Nonunion of Unstable Distal Clavicle Fracture Patients Treated with Open Reduction and Internal Fixation by Ma C, Lu W, Liang L, Huang K, Zou J

“…Changke Ma,1,* Wei Lu,2,3,* Limei Liang,4,* Kaizong Huang,3 Jianjun Zou3,5 1Department of Orthopaedics, Nanjing Luhe People’s Hospital, Yangzhou University, Nanjing, People’s Republic of China; 2School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, People’s Republic of China; 3Department of Pharmacology, Nanjing First Hospital, Nanjing Medical University, Nanjing, People’s Republic of China; 4Department of Rehabilitation, Nanjing Luhe People’s Hospital, Yangzhou University, Nanjing, People’s Republic of China; 5Department of Pharmacy, Nanjing First Hospital, China Pharmaceutical University, Nanjing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Kaizong Huang, Email kzhuang@nju.edu.cn Jianjun Zou, Email zoujianjun100@126.comBackground: This retrospective study aims to predict the risk of 3-month nonunion in patients with unstable distal clavicle fractures (UDCFs) treated with open reduction and internal fixation (ORIF) using machine learning (ML) methods. …”
Get full text

Rhein Mitigates Lung Injury in Severe Acute Pancreatitis Through the Inhibition of MARK4-Mediated Microtubule Destabilization by Sun Z, Liu J, Ge P, Cao Y, Liu J, Wen H, Luo X, Pei B, Jin Z, Li H, Xun L, Luo Y, Yang Q, Chen H

“…Zhenxuan Sun,1– 3,* Jie Liu,1– 3,* Peng Ge,1– 3,* Yinan Cao,4 Jin Liu,1– 3 Haiyun Wen,1– 3 Xinyu Luo,1– 3 Boliang Pei,1– 3 Zuocang Jin,1,3 Huijuan Li,3 Lu Xun,1– 3 Yalan Luo,5 Qi Yang,6 Hailong Chen1– 3 1Department of General Surgery, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, 116011, People’s Republic of China; 2Institute (College) of Integrative Medicine, Dalian Medical University, Dalian, Liaoning, 116011, People’s Republic of China; 3Laboratory of Integrative Medicine, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, 116011, People’s Republic of China; 4Day Surgery Center, Dalian Municipal Central Hospital, Dalian, Liaoning, 116033, People’s Republic of China; 5Department of Gastroenterology, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, 116011, People’s Republic of China; 6Department of Traditional Chinese Medicine, The Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, 116023, People’s Republic of China*These authors contributed equally to this workCorrespondence: Hailong Chen, Department of General Surgery, The First Affiliated Hospital of Dalian Medical University, Zhongshan Road 222, Dalian, Liaoning, 116011, People’s Republic of China, Tel +86 411 83635963, Fax +86 411 83622844, Email chenhailong@dmu.edu.cnPurpose: Explore the therapeutic effect and molecular mechanism of rhein on severe acute pancreatitis associated acute lung injury (SAP-ALI).Methods: The SAP-ALI rat model was constructed by retrograde injection of 5% sodium taurocholate into the pancreaticobiliary duct, and pulmonary microvascular endothelial cell (PMVEC) injury model was induced by LPS. …”
Get full text