Use of serum long non-coding RNA expression panel as a marker for diabetic retinopathy by Eric Wang, Shali Chen, Anorin Ali, Biao Feng, Selina Liu, John Gonder, Tom Sheidow, Phil Hooper, Subrata Chakrabarti, Subrata Chakrabarti, Subrata Chakrabarti

“…However, due to a variety of factors, many patients can still fall through the cracks with the current screening methods.MethodsSeveral long non-coding RNAs (lncRNAs), essential regulators of physiological and pathological processes, were previously identified by us as potential markers for DR phenotypes. …”
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Validation of Automated Respiratory Event Scoring in Type 3 Home Sleep Apnea Testing by Shiroshita N, Obata R, Kawana F, Kato M, Sato A, Ishiwata S, Yatsu S, Matsumoto H, Shitara J, Murata A, Shimizu M, Kato T, Suda S, Tomita Y, Hiki M, Naito R, Kasai T

“…The REIs were calculated using these three methods and expressed as mREI, aREI, and sREI, respectively. …”
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Correlation of four-dimensional ultrasound strain analysis with computed tomography angiography wall stress simulations in abdominal aortic aneurysms by Wojciech Derwich, MD, MHBA, Manuel Schönborn, MEng, Christopher Blase, RNDr, Andreas Wittek, Dr-Ing, Kyriakos Oikonomou, MD, PhD, Dittmar Böckler, MD, PhD, MHBA, Philipp Erhart, MD, PhD, MHBA

“…At the current stage of development, the two methods are considered complementary and may optimize a more patient-specific rupture risk prediction in the future.…”
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The ICAO Council as a Dispute Settlement Body: Theoretical and Practical Issues by D. V. Ivanov, V. G. Donakanian

“…The methodological basis consists of general scientific and special research methods, including analysis, synthesis, systematisation, as well as formal-legal, formallogical and critical-legal methods.   …”
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Cost-Effectiveness of Single-Inhaler Versus Multiple-Inhaler Triple Therapy in COPD: A German Healthcare Perspective by Beeh KM, Claussen J, Shah D, Martin A, Kendall R, Dasari P, Ismaila AS, Noorduyn SG

“…Kai-Michael Beeh,1,* Jing Claussen,2,* Dhvani Shah,3 Alan Martin,4 Robyn Kendall,5 Priyadarsini Dasari,6 Afisi S Ismaila,7,8 Stephen G Noorduyn7,9 1Insaf Respiratory Research Institute, Taunusstein, Germany; 2Global Medical Affairs, GSK, Munich, Germany; 3Insights, Evidence and Value – Health Economics & Epidemiology, ICON Plc, NJ, USA; 4Value Evidence and Outcomes, GSK, Brentford, Middlesex, UK; 5ICON Health Economics, ICON Plc, Vancouver, Canada; 6Insights, Evidence and Value – Health Economics & Epidemiology, ICON Plc, Houston, TX, USA; 7Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada; 8Value Evidence and Outcomes, GSK, Collegeville, PA, USA; 9Value Evidence and Outcomes, GSK, Ontario, Canada*These authors contributed equally to this workCorrespondence: Jing Claussen, Global Medical Affairs, GSK, Munich, Germany, Tel +4915259965322, Email jing.x.claussen@gsk.comPurpose: The INTREPID trial showed that once-daily single-inhaler triple therapy (SITT) using fluticasone furoate, umeclidinium, and vilanterol (FF/UMEC/VI) offers clinical benefits versus non-ELLIPTA multiple-inhaler triple therapy (MITT) for the management of chronic obstructive pulmonary disease (COPD) in real-world clinical practice. …”
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Investigating the Impact of Circulating Immune Cells on Acne Using Mendelian Randomization by Wang X, Guan S, Xia Z, Zhang X, Bai Y, Li Q, Li H, Yang R

“…Rigorous instrumental variables selection was followed by causal inference using five complementary methods, including MR-Egger, weighted median, simple mode, inverse variance weighted (IVW), and weighted mode methods. …”
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Multiple Hub Genes as Diagnostic and Therapeutic Targets Inducing Inflammation and Angiogenesis in Retinopathy of Prematurity by Du C, Tian Y, Liu Y, Shi Y, Chen X, Chai H, Zhang Y, Shen H, Zhang L

“…Hub genes were screened by three machine learning methods and validated by nomograms, ROC curves and qRT-PCR. …”
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Study of malnutrition in patients with idiopathic pulmonary fibrosis by Aya A. Dayem, Esraa R. Knany, Dina Ruby

“…Our findings also revealed that measuring BMI and being less than or equal to 22.1 kg/m2 and mid-arm circumference (MAC) less than or equal 28.5 cm is significantly related to low free fat mass index (malnutrition) and increases that risk by 31.63 folds. …”
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Non-Polynomial Spline for Singularly Perturbed Differential-Difference Equation with Mixed Shifts and Layer Behavior by Shilpa Malge, Ram Kishun Lodhi

“…Numerical examples are solved to support the method and check the validity of the findings. The numerical order of convergence is determined and presented in the tables, along with the comparison of the results with the other existing methods. …”
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Interest groups in Lithuania: dynamics of development and characteristics of institutionalization by Alvidas Lukošaitis

“…Second, there are no terms of equality and uniform competition among the interest groups themselves - decisions in public politics remind from time to time that some of the groups, due to some reasons, are more equal than others. …”
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Kształtowanie Belek Sprężonych przez Wyrównywanie Skrajnych Naprężne by A. Brandt

“…It is not maintained that the method of equalizing the stresses is the only possible for the determation of the shape of prestressed beams. …”
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Pedagogical and evaluative competencies for the 21st century in molecular biology education and their relationship with honors programs: a systematic literature review by Ricardo Pérez Zúñiga, Mario Martínez García, Marina Campos-Valdez, Laura V. Sánchez-Orozco

“…Literature suggests that teaching methods should assess both knowledge and disciplinary skills, as this approach is a prerequisite for student employability in biomolecular sciences.MethodsIn this systematic review, we conducted a search in Web of Science and Scopus, selecting 55 studies that met the inclusion criteria for the development of this research. …”
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Practical guidance to handle missing values in the 25-question Geriatric Locomotive Function Scale (GLFS-25): a simulation study by Sakae Tanaka, Keiko Yamada, Toru Ogata, Hirotaka Chikuda, Kozo Nakamura, Takuya Kawahara, Ryohei Terashima, Ikumi Takashima, Hiromasa Miura, Takashi Ohe

“…Complete case analysis showed the largest bias, and the performances of the single imputation were between those methods. The relative performances were similar across the three datasets. …”
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Diagnostic capabilities of the virtual bronchoscopy at advanced neoplastic process of esophagus with formation of tracheobronchial fistula: Description of a case by M. A. Mitev, N. Trajkova, D. Arabadzhiev, S. Valkanov, N. Georgieva, E. Obretenov

“…Conclusion: The VB is a successful method equally effective compared to the FB, to diagnose of advanced neoplastic processes.…”
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Patient stratification and choice of therapy based on blood gene expression profiles in rheumatoid arthritis by E. V. Chetina, G. A. Markova

“…Moreover, RA patients are an exclusively heterogeneous group, so not all of them respond equally well to treatment. In this regard, there is a need for personalized therapy. …”
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The Inequality of Material Living Conditions in EU Countries by Ona Gražina Rakauskienė, Lina Volodzkienė

“…The standard means of measuring these differences in equality include methods and aspects such as looking at inequalities in income and consumption, but these criteria do not reflect the actual level of inequality. …”
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Modelling of examinations of artery wall thickness changes by Tadeusz POWAŁOWSKI, Janusz WÓJCIK, Zbigniew TRAWIŃSKI

“…The internal radius of the artery model was equal 3 mm for the diastolic pressure and 3.3 mm for the systolic pressure. …”
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A New Framework to Evaluate Sustainable Higher Education: An Analysis of China by Yuqing Geng, Hongwei Zhu, Nan Zhao, Qinghua Zhai

“…This article selects regions of China and compares the development status and coupling coordination level of sustainable higher education both temporally and spatially from the aspects of expenditure, existence, efficiency, effectiveness, economy, equity, and equality based on the 7E framework with the combined method of information entropy weight analysis and technique for order preference by similarity to an ideal solution and coupling coordination degree model. …”
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Obstetric violence: reflection on reporting to achieve sustainable development goals by Emmanuele Mainart Ildefonso, Laura Christina Macedo, Tatiane Herreira Trigueiro, Isabele Melo Martins

“…ABSTRACT Objectives: to explain obstetric violence, its consequences, and the importance of mandatory reporting to achieve the Sustainable Development Goals. Methods: a reflective study based on references and the researchers’ expertise on the subject. …”
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Opinions on Amblyopia Treatment in Microtropia – A Questionnaire Study of Orthoptists in Scandinavia by Jannicke Røe, Gemma Arblaster

“…Background: Microtropia is a small angle strabismus of less than or equal to ten prism diopters. It often co-exists with anisometropia, and patients may require amblyopia treatment. …”
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