Predictive Scores for Identifying Chronic Opioid Dependence After General Anesthesia Surgery by Sun M, Chen WM, Lu Z, Lv S, Fu N, Yang Y, Wang Y, Miao M, Wu SY, Zhang J

“…Mingyang Sun,1,2,* Wan-Ming Chen,3,4,* Zhongyuan Lu,1,2 Shuang Lv,1,2 Ningning Fu,1,2 Yitian Yang,1,2 Yangyang Wang,1,2 Mengrong Miao,1,2 Szu-Yuan Wu,5– 11 Jiaqiang Zhang1,2 1Department of Anesthesiology and Perioperative Medicine, People’s Hospital of Zhengzhou University, Henan Provincial People’s Hospital, Zhengzhou, Henan, People’s Republic of China; 2Academy of Medical Sciences of Zhengzhou University, Zhengzhou, Henan, People’s Republic of China; 3Graduate Institute of Business Administration, College of Management, Fu Jen Catholic University, Taipei, Taiwan; 4Artificial Intelligence Development Center, Fu Jen Catholic University, Taipei, Taiwan; 5Department of Food Nutrition and Health Biotechnology, College of Medical and Health Science, Asia University, Taichung, Taiwan; 6Big Data Center, Lo-Hsu Medical Foundation, Lotung Poh-Ai Hospital, Yilan, Taiwan; 7Division of Radiation Oncology, Lo-Hsu Medical Foundation, Lotung Poh-Ai Hospital, Yilan, Taiwan; 8Department of Healthcare Administration, College of Medical and Health Science, Asia University, Taichung, Taiwan; 9Cancer Center, Lo-Hsu Medical Foundation, Lotung Poh-Ai Hospital, Yilan, Taiwan; 10Centers for Regional Anesthesia and Pain Medicine, Taipei Municipal Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan; 11Department of Management, College of Management, Fo Guang University, Yilan, Taiwan*These authors contributed equally to this workCorrespondence: Szu-Yuan Wu, College of Medical and Health Science, Asia University, Taichung, Taiwan; Director, Big Data Center, Lo-Hsu Medical Foundation, LotungPoh-Ai Hospital, No. 83, Nanchang St., Luodong Township, Yilan County, 265, Taiwan, Email szuyuanwu5399@gmail.com Jiaqiang Zhang, Department of Anesthesiology and Perioperative Medicine, Henan Provincial People’s Hospital, People’s Hospital of Zhengzhou University, No. 7 Weiwu Road, Jinshui District, Zhengzhou, Henan, 450003, People’s Republic of China, Email jiaqiang197628@163.comPurpose: To address the prevalence and risk factors of postoperative chronic opioid dependence, focusing on the development of a predictive scoring system to identify high-risk populations.Methods: We analyzed data from the Taiwan Health Insurance Research Database spanning January 2016 to December 2018, encompassing adults undergoing major elective surgeries with general anesthesia. …”
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Activation of TLR4/CCL2 in Intact Neurons Drives Radicular Injury-Induced Global Nerve Trunk Hypersensitivity in Radiculopathy Preclinical Models by Tong SH, Zhou J, Ye F, Ding P, Mei JL, Liao P, Lu YF, Zong Y, Gao CA, Zhang SY, Gao JJ, Liu DL, Huang YG

“…However, the underlying mechanisms remain unclear.Methods: An L5 spinal nerve compression rat model was established. …”
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The effects of normal and interrupted sleep combined with acute caffeine supplementation on some immune system indices and anaerobic power in male athletes by Mohammad hossein Hashemzadeh, Farhad Rahmaninia, Payam Saidie

“…Participants were randomly and equally assigned to 2 groups and 2 sessions: 1) normal sleep, caffeine/placebo (NSP/NSC) and 2) Interrupted sleep, caffeine/placebo (ISP/ISC). …”
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Exploring Autophagy-Related Gene Expression in Hepatocellular Carcinoma via TCGA, GEPIA2, and HPA Databases: Implications for Prognosis by Gu X, Chen Y, Hu X, Li Y, Zhu R, Li H, Yuan Z, Wang Y

“…Xiangran Gu,1,* Yuan Chen,2,* Xinyue Hu,1,* Yunhui Li,3 Renlong Zhu,2 Hongxu Li,1 Zhengrong Yuan,1 Yajie Wang2,3 1College of Biological Sciences and Technology, Beijing Forestry University, Beijing, People’s Republic of China; 2Department of Clinical Laboratory, Peking University Ditan Teaching Hospital, Beijing, People’s Republic of China; 3Department of Clinical Laboratory, Beijing Ditan Hospital, Capital Medical University, Beijing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Zhengrong Yuan, College of Biological Sciences and Technology, Beijing Forestry University, No. 35 Tsinghua East Road, Haidian District, Beijing, 100083, People’s Republic of China, Email zryuan@bjfu.edu.cn Yajie Wang, Department of Clinical Laboratory, Beijing Ditan Hospital, Capital Medical University, Beijing, People’s Republic of China, Email wangyajie@ccmu.edu.cnObjective: This study aimed to identify autophagy-related genes (ARGs) with prognostic significance in hepatocellular carcinoma (HCC) using bioinformatics and survival analysis.Materials and Methods: ARGs were sourced from multiple references, including the Human Autophagy Database (HADb), relevant literatures, the Gene Set Enrichment Analysis (GSEA), and a final list was confirmed after eliminating duplicate entries. …”
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Safety, tolerability and immunogenicity of a condensed, multi-dose prime regimen of PfSPZ Vaccine for the prevention of Plasmodium falciparum malaria infection by Andrea A. Berry, Thomas L. Richie, L. W. Preston Church, Matthew B. Laurens, Colleen Boyce, Natasha KC, Sudhaunshu Joshi, Abra Rachida Koudjra, Lauryn Butler, Mei-Chun Chen, Yonas Abebe, Tooba Murshedkar, Eric R. James, Peter F. Billingsley, B. Kim Lee Sim, Stephen L. Hoffman, Kirsten E. Lyke

“…Solicited local and systemic adverse events recorded for 2 and 7 days after immunizations, respectively, occurred with equal frequency and severity in the 23 vaccinees and 7 controls receiving two immunizations, as did unsolicited adverse events recorded for 28 days and laboratory abnormalities 1 and 5 weeks after V2. …”
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Correlation of Novel Inflammation Index with Postoperative Acute Kidney Injury in Patients with Joint Arthroplasty: A Retrospective Cohort Study by Yan YT, Liu R, Liu J, Zhang WJ, Wang S, Tang TY, Lei YQ, Zhu XY, Liu KX, Zheng QJ, Liu HM

“…This study investigated the association between novel inflammation indices and postoperative AKI.Methods: This retrospective cohort study included 1434 patients who underwent hip or knee arthroplasty, with 1225 patients comprising the complete case analysis dataset. …”
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Real-World Assessment of the Association Between PCSK9i Adherence and LDL Reduction and Variability in a Chinese Clinical Practice by Ye X, Zhang S, Zhong X, Li M, Liu M, Zhuang X, Liao X

“…Xiaomin Ye,1,2,* Shaozhao Zhang,1,2,* Xiangbin Zhong,1,2 Miaohong Li,1,2 Menghui Liu,1,2 Xiaodong Zhuang,1,2 Xinxue Liao1,2 1Cardiology Department, First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, People’s Republic of China; 2NHC Key Laboratory of Assisted Circulation, Sun Yat-Sen University, Guangzhou, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xinxue Liao, Cardiology Department, First Affiliated Hospital, Sun Yat-Sen University, 58 Zhongshan 2nd Road, Guangzhou, 510080, People’s Republic of China, Tel +86-13903063724, Fax +86-020-28823388, Email liaoxinx@mail.sysu.edu.cn Xiaodong Zhuang, Cardiology Department, First Affiliated Hospital, Sun Yat-Sen University, 58 Zhongshan 2nd Road, Guangzhou, 510080, People’s Republic of China, Tel +86-13760755035, Email zhuangxd3@mail.sysu.edu.cnBackground: Real-world evidence about adherence to proprotein convertase subtilisin/kexin type-9 inhibition (PCSK9i) is needed in Chinese population.Objective: We aimed to evaluate the adherence patterns using anti-PCSK9 monoclonal antibody in Chinese clinical practice and explored the association between adherence to PCSK9i and low-density lipoprotein cholesterol (LDL-C) reduction ratio and variability.Methods: A total of 5373 patients initiating PCSK9i in the First Affiliated Hospital of Sun Yat-sen University were included as sub-analysis of the RED-CARPET registry. …”
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Neoadjuvant sintilimab and chemotherapy followed by transoral surgery for HPV-positive resectable oropharyngeal cancer: a single-arm, two-centre, phase 2 trialResearch in context by Shida Yan, Xing Zhang, Fengjiao Li, Ankui Yang, Hui Li, Wanming Hu, Qiaohong Lin, Xiyuan Li, Mingyuan Du, Jingtao Chen, Guodong Man, Jianwei Zhang, Xuemei Fang, Li Ning, Shiting Zhang, Lili Han, Yanmei Ma, Jun Wang, Shuwei Chen, Ming Song

“…The primary endpoint was major pathological response (MPR), defined as the residual viable tumor of less than or equal to 10% in the primary lesion. The study is registered with Chinese Clinical Trial Registry (ChiCTR2200058650) and is ongoing. …”
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Acupuncture as adjunctive therapy for acute cerebral infarction: a randomized clinical trial by Jiang-Peng Cao, Jiang-Peng Cao, Jiang-Peng Cao, Xin-Yue Du, Xiao-Xi Liu, Xiao-Xi Liu, Meng-Han Li, Meng-Han Li, Man Zhang, Sheng-Xuan Guo, Sheng-Xuan Guo, Qiu-Han Cai, Qiu-Han Cai, Jia-Xin Zhang, Jia-Xin Zhang, Jia-Xin Zhang, Shan-Shan Sun, Shan-Shan Sun, Shan-Shan Sun, Jia-Wei Han, Lin-Ling Chen, Na Zheng, Lan-Yu Jia, Gui-Ping Li, Gui-Ping Li, Yuan-Hao Du, Yuan-Hao Du

“…We aimed to investigate the efficacy and safety of acupuncture as adjunctive therapy to improve neurological function in patients with ACI.MethodsThe multicenter, sham-controlled, patient- and assessor-blinded randomized controlled trial was conducted in 4 tertiary hospitals in China from January to September 2024. …”
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The ATLAS/NOA-29 study protocol: a phase III randomized controlled trial of anterior temporal lobectomy versus gross-total resection in newly-diagnosed temporal lobe glioblastoma by Matthias Schneider, Anna-Laura Potthoff, Yahya Ahmadipour, Valeri Borger, Hans Clusmann, Stephanie E. Combs, Marcus Czabanka, Lasse Dührsen, Nima Etminan, Thomas M. Freiman, Ruediger Gerlach, Florian Gessler, Frank A. Giordano, Eleni Gkika, Roland Goldbrunner, Erdem Güresir, Hussam Hamou, Peter Hau, Sebastian Ille, Max Jägersberg, Naureen Keric, Maryam Khaleghi-Ghadiri, Ralph König, Jürgen Konczalla, Harald Krenzlin, Sandro Krieg, Aaron Lawson McLean, Julian P. Layer, Jens Lehmberg, Vesna Malinova, Bernhard Meyer, Hanno S. Meyer, Dorothea Miller, Oliver Müller, Christian Musahl, Barbara E. F. Pregler, Ali Rashidi, Florian Ringel, Constantin Roder, Karl Rössler, Veit Rohde, I. Erol Sandalcioglu, Niklas Schäfer, Christina Schaub, Nils Ole Schmidt, Gerrit A. Schubert, Clemens Seidel, Corinna Seliger, Christian Senft, Julia Shawarba, Joachim Steinbach, Veit Stöcklein, Walter Stummer, Ulrich Sure, Ghazaleh Tabatabai, Marcos Tatagiba, Niklas Thon, Marco Timmer, Johannes Wach, Arthur Wagner, Christian Rainer Wirtz, Katharina Zeiler, Thomas Zeyen, Patrick Schuss, Rainer Surges, Christine Fuhrmann, Daniel Paech, Matthias Schmid, Yvonne Borck, Torsten Pietsch, Rafael Struck, Alexander Radbruch, Christoph Helmstaedter, Robert Németh, Ulrich Herrlinger, Hartmut Vatter

“…Translating the ATL approach from epilepsy surgery to the neuro-oncological field may provide a model for investigating supramarginal resection in glioblastomas located in the anterior temporal lobe. Methods The ATLAS/NOA-29 trial is a prospective, multicenter, multinational, phase III randomized controlled trial designed to compare ATL with standard gross-total resection (GTR) in patients with newly-diagnosed anterior temporal lobe glioblastoma. …”
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The effects of surgeon handedness on the efficacy and safety of proximal femoral nail antirotation fixation for intertrochanteric femur fractures in elderly patients: A single Cent... by Xiao-Feng Liu, Xiao-Feng Liu, Xiao-Feng Liu, Xiao-Feng Liu, Yong-Qiang Zheng, Yong-Qiang Zheng, Liang Lin, Liang Lin, Zhen-Yu Lin, Zhen-Yu Lin, Hong-Peng Zhang, Hong-Peng Zhang, Xiao-Peng Huang, Xiao-Peng Huang, Ze-Feng Wang, Ze-Feng Wang, Yang-Zhen Fang, Yang-Zhen Fang, Wen-Ming Zhang, Wen-Ming Zhang, Wen-Ming Zhang, Wen-Ming Zhang, Xin-Yu Fang, Xin-Yu Fang, Xin-Yu Fang, Xin-Yu Fang, Jin-Shan Zhang, Jin-Shan Zhang

“…Equal numbers of left and right PFNA fixation were performed by four surgeons, two right-handed and two left-handed. …”
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Levels of total IgE versus specific IgE during childhood for defining and predicting T2-high asthma by Tamo Sultan, MD, Frederikke Skov, MD, Nicklas Brustad, MD, PhD, Nilo Vahman, MD, PhD, Jakob Stokholm, MD, PhD, Klaus Bønnelykke, MD, PhD, Ann-Marie Malby Schoos, MD, PhD, DMSc, Bo Chawes, MD, PhD, DMSc

“…Conclusion: Elevated tIgE and sIgE are equally useful stand-alone biomarkers for defining and predicting risk of T2-high asthma in childhood.…”
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Study on the risk factors for colorectal polyp recurrence: a cross-sectional retrospective cohort study by Fang Li, Fang Li, Mengge Lu, Mengge Lu, Bo Xu, Zheng Xiang, Zheng Xiang, Yuan Zhang, Yuan Zhang, Boran Cao, Xuewei Li, Xuewei Li, Yanan Wu, Yanan Wu, Rongrong Zheng, Rongrong Zheng, Qin Cai, Qin Cai, Jun Shen, Pengfei Xin, Pengfei Xin, Lianbo Xiao, Lianbo Xiao, Yanqin Bian, Yanqin Bian

“…Patients with a risk prediction model value greater than or equal to 0.44 have increased odds to experience postoperative recurrence.…”
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The EORTC QLQ-F17 as a shortened version of the EORTC QLQ-C30 to assess self-reported functioning in cancer patients: investigating equivalence and psychometric properties in a ran... by Florian Zeman, Johannes M. Giesinger, Tobias Pukrop, Morten Aa Petersen, Mogens Groenvold, Sandra Nolte, Dagmara Kuliś, Sunil Shrestha, Laurence Leysen, Kim Cocks, Corneel Coens, Georgios Ioannidis, Cecilia Pompili, Michael Koller

“…The QLQ-F17 is conceived an equivalent to the functional part of the QLQ-C30, but to date there is no empirical evidence to support this rationale. Methods: This randomized, cross-over, multi-national, questionnaire-based study investigates the equivalence and psychometric properties of the QLQ-F17 compared to the functional scales of the QLQ-C30. …”
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Dynamics of Clinical Manifestations and Social Functioning in Schizophrenia: A Non-interventional Observational Study of Paliperidone Palmitat Dosage Forms by Aleksandr M. Reznik, Olga A. Karpenko, Elena A. Shumakova, Aleksandr V. Mudrak, Andrey V. Sokolov, Svetlana V. Nazimova, Alina M. Saifulina, Anton M. Eliseenko, Tatjana K. Matvievskaya, Angelina N. Khannanova, Vladimir I. Revenko, Dmitriy V. Scherbakov, Yuriy L. Martynyuk, Aleksandr L. Arbuzov, Oleg A. Yacenko, Polina N. Alekseeva, Aleksandr B. Berdalin, Larisa A. Burygina

“…CONCLUSION: Treatment with different forms of paliperidone provides a roughly equal pace reduction in the severity of schizophrenia, including positive and negative symptoms. …”
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Wound Healing Properties of Plant-Based Hydrogel and Oleogel Formulations in a Rat Scald Burn Model by Oana Janina Roșca, Alexandru Nistor, Georgeta Hermina Coneac, Ioana Viorica Olariu, Ana-Maria Cotan, Roxana Racoviceanu, Elena Rodica Heredea, Adelin Ciudoiu, Gabriela Didea, Camelia Mihaela Lupou, Florin Borcan, Teodora Hoinoiu, Cristina Adriana Dehelean, Lavinia Lia Vlaia, Codruța Marinela Șoica

“…Post-burn, rats were divided into three equal subgroups, and topical formulations were applied daily. …”
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Decolonization Projects by Cornelius Ewuoso

“…International Journal of Qualitative Methods, 20, 16094069211014766. [10] Abimbola Seye 2023. …”
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The Effect of Postoperative Tranexamic Acid and Dexamethasone on Quality of Recovery After Arthroscopic Rotator Cuff Repair: a Double-Blinded, Randomized Controlled Trial by Jiang X, Xu C, Yuan C, Gao W, Liu W, Wang Y, Wang H, Yu W, He Y

“…Our goal is to relieve the acute postoperative pain and promote fast recovery and rapid discharge for ARCR patients.Patients and Methods: Ninety-six patients who underwent ARCR from December 2023 to March 2024 were enrolled in this double-blinded, randomized control trial (Registration number, ChiCTR2300078507). …”
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Comparative Analysis of ICS Combined with LABA versus Addition of Omalizumab on Transcriptomic Expression Profiles in Patients with Allergic Asthma by Liang YR, Chang CH, Huang SY, Wu YK, Yang MC, Huang KL, Tzeng IS, Hsieh PC, Lan CC

“…Therefore, this study aims to investigate the transcriptomic expression profiles and clinical outcomes between patients receiving ICS with LABA therapy and those adding omalizumab.Materials and Methods: This is a prospective, real-world study that enrolled 26 participants, divided into three groups: Group 1, ICS with LABA (n=10); Group 2, ICS with LABA plus omalizumab (n=12); and Group 3, healthy controls (n=4). …”
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PENURUNAN KADAR GULA DARAH AKIBAT PEMBERIAN EXTRA VIRGIN OLIVE OIL (Studi pada Tikus Galur Sprague Dawley yang Diinduksi Pakan Tinggi Lemak) by SH Bintari, K Nugraheni

“…It is caused by hyperglycemia induced by high-fat diet. Several alternative methods of treatment and prevention widely used is consuming olive oil. …”
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