Maltreatment and parenting in youth with primary and secondary callous‐unemotional traits: Anxiety matters by Jessica J. Todorov, Gregor Kohls, Ruth Pauli, Jack Rogers, Anka Bernhard, Katharina Ackermann, Nora M. Raschle, Jules R. Dugre, Aranzazu Fernandez‐Rivas, Miguel Angel Gonzalez‐Torres, Amaia Hervas, Areti Smaragdi, Karen Gonzalez, Ágnes Vetró, Dimitris Dikeos, Arne Popma, Christina Stadler, Kerstin Konrad, Christine M. Freitag, Graeme Fairchild, Rory T. Devine, Stephane A. De Brito

“…Youth with primary and secondary CU traits were equally high on levels of abuse, neglect, and maladaptive parenting (all p values >0.05). …”
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Impact of multidimensional assessment on anti-fracture treatment decisions in patients with fragility hip fractures within a Fracture Liaison Service by Chiara Ceolin, Stefania Sella, Cristina Simonato, Ester Bukli, Giulia Bano, Valentina Camozzi, Anna Bertocco, Marco Onofrio Torres, Alberta Cecchinato, Martin Diogo, Mor Peleg Falb, Francesca Guidolin, Maria Grazia Rodà, Michele Cannito, Antonio Berizzi, Andrea Venturin, Vito Cianci, Elisa Pala, Mariachiara Cerchiaro, Deris Gianni Boemo, Maria Vittoria Nesoti, Gaetano Paride Arcidiacono, Paolo Simioni, Pietro Ruggieri, Giuseppe Sergi, Sandro Giannini, Marina De Rui, on behalf of the Hip-POS working group

“…While FLS models effectively reduce refracture risk and maintain cost-effectiveness, it is unclear if these benefits apply equally to all patients, especially those with higher comorbidities and reduced functional capacity, who may face worse prognoses. …”
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A Multicenter Randomized Double-Blind Vehicle-Controlled Parallel Group Phase 2 Study Evaluating the Efficacy and Safety of GN-037 Cream in Patients with Mild-to-Moderate Plaque Ps... by Burhan Engin, Müge Güler Özden, Özge Sevil Karstarlı Bakay, Selda Pelin Kartal, İlkin Zindancı, Salih Levent Çınar, Recep Dursun, Gizem Pehlivan Ulutaş, Tuğba Özkök Özkök Akbulut, Fatma Aslı Hapa, Emel Bülbül Başkan, Mehmet Melikoğlu, Algün Polat Ekinci, Neslihan Demirel Öğüt, Pelin Hızlı, Zafer Türkoğlu, Özlem Su Küçük, Zeynep Topkarcı, Ümit Türsen, Filiz Canpolat, Hanife Uçgun, Şirin Yaşar, Selami Aykut Temiz, Asena Çiğdem Doğramacı, Sedat Altuğ, Serhat Kozlu, Nadir Ulu, Server Serdaroğlu

“…The present multicenter randomized double-blind vehicle-controlled parallel group phase 2 study aimed to investigate the efficacy and safety of GN-037 in patients with mild-to-moderate plaque psoriasis (MMPP). Methods Patients (n = 190) were randomized (2:2:1) to receive GN-037 or CP or vehicle (V) cream twice daily to a selected target body lesion for 4 weeks. …”
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Optimizing treatment for depression in primary care using psychotherapy versus antidepressant medication in a low-resource setting: protocol for the OptimizeD randomized controlled... by Julia R. Pozuelo, Anuja Lahiri, Rahul S. P. Singh, Arvind Kushwah, Mimansa Khanduri, Akanksha Shukla, Azaz Khan, Sruthi G., Varun Shende, Yashika Parashar, Yashwant K. Mehra, Anant Bhan, Ronald C. Kessler, Daisy R. Singla, John A. Naslund, Karmel W. Choi, Pim Cuijpers, Robert DeRubeis, Mohammad M. Herzallah, Chunling Lu, Jordan W. Smoller, Tyler J. VanderWeele, Abhijit R. Rozatkar, Tamonud Modak, Michelle Melwyn Joel, Debasis Biswas, Shubham Atal, Umay Kulsum, Steven D. Hollon, Vikram Patel

“…The Optimizing Depression (OptimizeD) trial aims to explore whether different patients respond differently to behavioral activation therapy versus antidepressant medication and if providing each patient with their optimal treatment improves outcomes in primary care. Methods We plan to randomize 1,500 patients with moderate to severe depression (defined as a Patient Health Questionnaire [PHQ-9] score ≥ 10) from primary healthcare settings in Bhopal, India, with equal allocation either to a culturally adapted behavioral activation therapy delivered by trained counselors (Healthy Activity Program) or to antidepressant medication (fluoxetine). …”
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Genomic analysis of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) causing infections in children—a Spanish multicenter study by Silvia García-Cobos, Silvia García-Cobos, Natalia Seco Alberca, Blanca Bravo-Queipo-de-Llano, Verónica Casquero-García, Eva Ramírez de Arellano, Eva Ramírez de Arellano, Cristina Calvo, Cristina Calvo, Guillermo Ruíz-Carrascoso, Guillermo Ruíz-Carrascoso, Iker Falces-Romero, Iker Falces-Romero, Nieves Larrosa Escartín, Nieves Larrosa Escartín, Nieves Larrosa Escartín, Belén Viñado-Perez, Belén Viñado-Perez, Miguel Ángel Martínez-López, Susana Melendo Pérez, Enrique Ruíz de Gopegui, Enrique Ruíz de Gopegui, Santiago Pérez Vázquez, Jaime Carrasco-Colom, Belén Aracil García, Belén Aracil García, María Pérez-Vázquez, María Pérez-Vázquez, Ana Méndez-Echevarría, Ana Méndez-Echevarría, Jesús Oteo Iglesias, Jesús Oteo Iglesias

“…This study investigated the molecular traits of community-associated methicillin-resistant S. aureus (CA-MRSA) isolates causing infections in children in Spain.MethodsAntibiotic susceptibility testing and whole-genome sequencing were performed in 98 CA-MRSA isolates (4.2 median age, 52% males). …”
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A Program for Master of Science in Environment and Natural Resources (MENR) by Kabale University

“…Utilize their skills to analyse relationships between agricultural production, natural resource depletion, climate change, pollution and land degradation and develop innovative methods and mitigate their effects. iii. Promote professional development through multidisciplinary approaches to solve challenges in environment and natural resources.…”
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A review of the statistical analysis of randomised controlled trials conducted within OCTRU by Alexander Ooms, Caitlin Waldron, Daphne Kounali, Ioana R. Marian, M. Sofia Massa, Nicholas Peckham, Matthew Parkes, Elizabeth Conroy, Jonathan A. Cook

“…We found most RCTs adopted what could be considered a ‘standard’ design, using appropriate, but not complex, analysis methods. Consideration of variation in practice across other groups, both academic and commercial, through a larger review would allow systematic exploration of methodological differences, less common study design usage, and would enable a fuller understanding of practice, outcomes, and methods used in different clinical areas and contexts.…”
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Sleep, physical activity, sedentary behavior, and risk of cataract: a cross-sectional and prospective study from UK Biobank by Yu Peng, Yuzhou Zhang, Ka Wai Kam, Mary Ho, Sunny Au, Xiujuan Zhang, Mandy PH Ng, Patrick Ip, Alvin Young, Chi Pui Pang, Clement C. Tham, Li Jia Chen, Jason C. Yam

“…This study aimed to examine the independent and combined effects of sleep, PA, and SB on cataract risk using data from the UK Biobank. Methods The cross-sectional analyses included 440,645 participants from the UK Biobank with complete data on sleep, PA, and SB. …”
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Gantry-based pencil beam scanning proton therapy for uveal melanoma: IMPT versus proton arc therapy by Hang Qi, Lei Hu, Sheng Huang, Yen-Po Lee, Francis Yu, Qing Chen, Yunjie Yang, Minglei Kang, Huifang Zhai, Milo Vermeulen, Andy Shim, Peter Park, Xuanfeng Ding, Jun Zhou, David H. Abramson, Jasmine H. Francis, Charles B. Simone, Christopher A. Barker, Haibo Lin

“…Abstract Background This study reports the single-institution clinical experience of multifield pencil beam scanning (PBS) intensity-modulated proton therapy (IMPT) and dosimetric comparison to proton arc for uveal melanoma (UM) in a regular PBS gantry room. Methods Eleven consecutive UM patients were treated with IMPT to 50 Gy in 5 fractions. …”
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Labor induction at 41+0 gestational weeks or expectant management for the nulliparous woman: The Finnish randomized controlled multicenter trial by Katariina Place, Leena Rahkonen, Aydin Tekay, Kirsi Väyrynen, Maija‐Riitta Orden, Marja Vääräsmäki, Jukka Uotila, Kati Tihtonen, Kirsi Rinne, Kaarin Mäkikallio, Seppo Heinonen, Heidi Kruit

“…Management practices of late‐ and post‐term pregnancies vary, and the optimal time point for intervention by labor induction is yet to be determined. Material and methods This randomized controlled trial of 381 nulliparous women with unripe cervices compared labor induction at 41+0 gestational weeks (early induction) with expectant management and labor induction at 41+5 to 42+1 gestational weeks (expectant management). …”
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Analysis of HMGCS2 Expression and TG Lipidomics in the Perirenal Adipose Tissue of Obese Diabetic Nephropathy Mice by Yuhong Huang, Miao Zeng, Mengxue Yang, Xiaodi Zheng, Lulu Jin, Rui Zhang, Yueyue Wu, Fei Li, Bo Yang, Jun Liu

“…This study was designed to elucidate the contribution of Hmgcs2 in the pathogenesis of obese diabetic kidney disease mice. Methods 12‐week‐old db/db (diabetic) and db/m (control) mice were fed high‐fat or normal diets, respectively. …”
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How does dispersal shape the genetic patterns of animal populations in European cities? A simulation approach by Savary, Paul, Tannier, Cécile, Foltête, Jean-Christophe, Bourgeois, Marc, Vuidel, Gilles, Khimoun, Aurélie, Moal, Hervé, Garnier, Stéphane

“…Context and objectives: Although urbanization is a major driver of biodiversity erosion, it does not affect all species equally. The neutral genetic structure of populations in a given species is affected by both genetic drift and gene flow processes. …”
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Retinal progenitor cells (jCell) for retinitis pigmentosa by Jing Yang, Jing Yang, Baruch D. Kuppermann, David Liao, Mitul C. Mehta, Chinhui Hsiang, Chinhui Hsiang, Steven Menges, Steven Menges, David S. Boyer, Henry Klassen, Henry Klassen

“…Each dose group contained equal numbers of subjects from Cohorts 1 and 2.ResultsIntravitreal RPC injection was well tolerated and associated with mostly transient mild to moderate adverse events. …”
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Comparison of Mallampati test in supine and upright positions with and without phonation in predicting difficult laryngoscopy and intubation in age groups 3-10 years. by P. Awasthi, S. Gautam, A. Malik, V. Singh, M. Kohali, S. Jafa, J. Agarwal

“…Aims and Objectives are To evaluate the ef- fect of phonation on Mallampati test in supine and upright position and correlation of it with laryngoscopic view using Cormack and Lehane score and difficulty in endotracheal intubation. Material and methods In this prospective study, 100 patients aged 3-12 years were recruited. …”
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Renoprotective Effects of Hydroxychloroquine and Folinic Acid via ET-1 and NLRP3 Modulation in Reducing Tubular Injury in A Rabbit Model of Methanol-induced Acute Kidney Injury by Prayuda Prayuda, I Gde Raka Widiana, Ketut Suega, Yenny Kandarini, Ni Wayan Winarti, Bambang Purwanto

“…Expression of NLRP3 was lowest in combination group (58.94±1.05%), followed by folinic acid and hydroxychloroquine group, which showed equal values (60.57±1.38%), compared to control group (72.15±1.02%). …”
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Randomized Clinical Trial of Surgical vs. Percutaneous vs. Hybrid Revascularization in Multivessel Coronary Artery Disease: Residual Myocardial Ischemia and Clinical Outcomes at On... by Vladimir Ganyukov, Nikita Kochergin, Aleksandr Shilov, Roman Tarasov, Jan Skupien, Wojciech Szot, Aleksandr Kokov, Vadim Popov, Kirill Kozyrin, Olga Barbarash, Leonid Barbarash, Piotr Musialek

“…We evaluated, in a randomized clinical trial, residual myocardial ischemia (RI) and clinical outcomes of MV-CAD revascularization using coronary artery bypass grafting (CABG), hybrid coronary revascularization (HCR), or MV-PCI. Methods. Consecutive MV-CAD patients (n = 155) were randomized (1 : 1 : 1) to conventional CABG (LIMA-LAD plus venous grafts) or HCR (MIDCAB LIMA-LAD followed by PCI for remaining vessels) or MV-PCI (everolimus-eluting CoCr stents) under Heart Team agreement on equal technical and clinical feasibility of each strategy. …”
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Measurement invariance of HIV-related stigma scales among men who have sex with men (MSM) and non-MSM populations: implications for comparative studies in China by Tianyue Mi, Xueying Yang, Guanghua Lan, Shan Qiao, Zhiyong Shen, Yuejiao Zhou, Xiaoming Li

“…This study examines the measurement invariance of internalized, anticipated, and enacted HIV-related stigma scales between MSM and non-MSM populations in China.MethodsData were derived from two studies: a prospective cohort study with 193 MSM and 579 non-MSM, and a cross-sectional survey of 402 MSM. …”
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Impact of male peer‐led outreach on uptake of HIV testing among male partners of pregnant women in Uganda: a randomized trial by Faith Naddunga, Michelle A. Bulterys, Agnes Nakyanzi, Deborah Donnell, Juliet Kyomugisha, Juliet E. Birungi, Paul Ssendiwala, Rogers Nsubuga, Timothy R. Muwonge, Joshua Musinguzi, Sue Peacock, Connie L. Celum, Andrew Mujugira, Monisha Sharma

“…We evaluated the impact of male peer outreach to increase HIV testing among partners of pregnant women in Uganda. Methods We conducted a randomized trial in Kampala, Uganda, enrolling an equal number of pregnant women with and without HIV from public ANC clinics who were randomized 1:1 to intervention or standard‐of‐care (SOC) with delayed intervention after 1 month. …”
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Prevalence and risk factors for antenatal anxiety in the first trimester among Chinese pregnant women by Li Zhang, Yan Zhang, Jin Liu, Yan Yu, Junzhe Cheng, Yumeng Ju, Mi Wang, Bangshan Liu, Shuyin Xu, Mengqi Xu, Yilin Peng, Jintao Xiong, Xuemei Qin, Zhuo Peng, Weiguo Mao, Meiqun Xiao

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A Tunnel Lining Line Identification Algorithm Based on Supervised Heatmap by Heng SONG, Yisheng ZHANG, Tianbao GENG, Dongjie WANG

“…Methods The algorithm is divided into two stages: keypoint detection and curve fitting. …”
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