Assessing Sedation Depth with PSI in Elderly ERCP Patients: A Prospective Cohort Study by Huang L, Liu LL, Lu YD, Zhuang MY, Dou W, Liu H, Ji FH, Peng K

“…We aimed to assess the correlation between PSI and Modified Observer’s Assessment of Alertness/Sedation (MOAA/S) scores in elderly patients undergoing ERCP.Methods: This prospective cohort study included 57 elderly patients scheduled for ERCP procedures. …”
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Exploring the Potential Regulatory Mechanisms of Mitophagy in Ischemic Cardiomyopathy by Li Z, Kong J, Xi S, Jin Z, Yang F, Zhu Z, Liu L

“…However, it is still uncertain how mitophagy related genes (MRGs) may affect the diagnosis of ICM.Patients and Methods: Data were obtained from public databases. …”
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Bromocriptine for Idiopathic Intracranial Hypertension: A Retrospective Multicenter Cohort Study by Morsy MM, Azzam AY, Mirdad MT, Abadi AM, Alqahtani SAM, Abukhadijah HJ, Elamin O, Morsy MD, Altschul DJ

“…This study aims to evaluate the safety and efficacy of bromocriptine in IIH management through a retrospective cohort analysis.Methods: A retrospective analysis was conducted, focusing on patients with IIH. …”
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Efficacy and Safety of Kilohertz Frequency Alternating Current with Non-Invasive Electrodes for Treatment of Neuropathic Pain After Spinal Cord Injury: A Randomized, Single-Blind,... by Shuai N, Zhu Y, Xiao Y, Yu B

“…Niannian Shuai,1,* Yuyao Zhu,2,* Yao Xiao,3,* Bin Yu4 1Department of Anesthesiology, Ningbo University Affiliated People’s Hospital, Zhejiang, People’s Republic of China; 2Department of Anesthesiology, Shanghai Tongji Hospital, Shanghai, People’s Republic of China; 3Department of Rehabilitation, Shanghai Tongji Hospital, Shanghai, People’s Republic of China; 4Department of Pain Rehabilitation, Yangzhi Rehabilitation Hospital, Affiliated with Tongji University, Shanghai, People’s Republic of China*These authors contributed equally to this workCorrespondence: Bin Yu, Department of Pain Rehabilitation, Yangzhi Rehabilitation Hospital, Affiliated with Tongji University, 2209 Guangxing Road, Songjiang District, Shanghai, 201613, People’s Republic of China, Tel +86 139 1810 8880, Email yubin@tongji.edu.cnObjective: To evaluate the effectiveness and safety of noninvasive kilohertz frequency alternating current (KHFAC) therapy for neuropathic pain in patients following spinal cord injury.Methods: In this randomized, single-blind, sham-controlled trial conducted from June 1, 2023, to January 31, 2024, 50 patients suffering from neuropathic pain post-spinal cord injury were assigned to receive either KHFAC or sham stimulation for 7 days, complemented by twice-daily oral administration of 75 mg pregabalin. …”
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Hyodeoxycholic Acid Ameliorates Metabolic Syndrome Through Pathways of Primary Bile Acid Synthesis and Fatty Acid Degradation: Insights From a Rat Model by Chen M, Huang K, Luo W, Zhang F, Gan H, Yang Z

“…Hyodeoxycholic acid (HDCA) has shown potential effects in non-alcoholic fatty liver disease (NAFLD), yet its role in MS is unexplored.Aim: This study aims to assess whether HDCA is a characteristic BA of MS and to investigate its intervention effects and potential mechanisms.Methods: We employed 16S rDNA sequencing and UHPLC-MS/MS to investigate the dynamics of the gut microbiota and BA profiles in rats and conducted a correlation study between indices, identifying HDCA as the potential characteristic BA. …”
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Effect of aloe vera and coconut in the management of xerostomia in patients with Sjogren’s syndrome: a crossover randomized clinical trial by Alaa Mahmoud, Basma Elsaadany, Mervat Eissa, Wesam Abd Elmoneim, Sherifa Tarek, Mai Zakaria

“…Aim: This study aimed to evaluate the efficacy of carboxymethyl cellulose (CMC)-based natural mixture of aloe vera gel and coconut oil as a salivary substitute in comparison to the conventional CMC for the management of xerostomia in a sample of patients with Sjogren’s syndrome (SS). Methods: This crossover randomized clinical trial included 24 patients diagnosed with SS. …”
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Red Blood Cell Distribution Width/Hematocrit Ratio: A New Predictor of 28 Days All-Cause Mortality of AECOPD Patients in ICU by Long Z, Zeng Q, Ou Y, Liu Y, Hu J, Wang Y, Wang Y

“…Furthermore, the utility of RDW/HCT in improving traditional ICU scoring systems remains unexplored.Patients and Methods: The optimal RDW/HCT ratio cutoff was identified via ROC curve analysis, guiding classification into high and low ratio groups. …”
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Establishment of a Novel in vitro Model of Sepsis-Induced Myocardial Injury Using Septic Serum: A Comprehensive Comparative Study by Yang H, Feng L, Jiang Z, Deng R, Wu X, Zeng K

“…This study aimed to systematically compare different in vitro models to determine the most appropriate model for studying the pathophysiological mechanisms of sepsis-induced myocardial injury.Materials and Methods: AC16 cardiomyocytes were treated with lipopolysaccharide (LPS), tumor necrosis factor-α (TNF-α), or septic serum for 24 hours to induce myocardial injury. …”
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Glomerular filtration rate dynamics in patients with diffuse large B-cell lymphoma during induction immunopolychemotherapy by A. S. Nozdricheva, I. B. Lysenko, N. K. Guskova, M. A. Konovalchik, A. A. Maslov, E. V. Shalashnaya

“…In group B, there were an equal number of patients with stages I–II and III–IV – 6 people. …”
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Availability and readiness of health facilities in Burkina Faso to provide antenatal care: trend analysis from 2012 to 2020 by Marie-Jeanne Offosse, Kadari Cissé, Désiré Somda, Anna Gage, Annie Haakenstad, Aduragbemi Banke-Thomas

“…Availability and readiness indices were calculated using the equal-weighted approach, and the domain-weighted approach was used for readiness only. …”
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Efficacy Assessment and Prognostic Value of Inflammatory Markers in Patients with Stage IV Acral and Cutaneous Melanoma Receiving PD-1 Inhibitors by Zhang Y, Qu Z, Xuan H, Lu L, Ding C, He Z, Gu K, Zhang Y

“…Few studies have examined the role of inflammatory markers in predicting the overall survival (OS) in stage IV acral melanoma (AM) and cutaneous melanoma (CM) patients receiving immunotherapy.Purpose: This study aimed to investigate the value of inflammatory markers in efficacy and prognosis for stage IV melanoma patients who underwent immunotherapy.Patients and Methods: This multicenter study reviewed the clinicopathological characteristics and inflammatory markers of 94 stage IV AM and CM patients receiving PD-1 inhibitors therapy. …”
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Predictive Value of TRUS and CEUS Parameters for Lymph Node Metastasis in Rectal Cancer: A Retrospective Study by Su S, Huang X, Li X, Meng J, Huang J

“…Shitao Su,* Xuanzhang Huang,* Xigui Li, Jun Meng, Jianyuan Huang Department of Medical Ultrasound, the First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi Zhuang Autonomous Region, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jianyuan Huang, Department of Medical Ultrasound, the First Affiliated Hospital of Guangxi Medical University, 6 Shuangyong Road, Nanning, Guangxi Zhuang Autonomous Region, 530001, People’s Republic of China, Tel +86 771 5356899, Email huangjianyuan@sr.gxmu.edu.cnPurpose: To assess the predictive value of transrectal ultrasound (TRUS) combined with qualitative and quantitative parameters of contrast-enhanced ultrasound (CEUS) for lymph node metastasis (LNM) in rectal cancer (RC).Patients and Methods: This retrospective study analyzed preoperative clinical data, qualitative and quantitative TRUS and CEUS parameters, and postoperative pathological data from 535 patients with RC confirmed by surgical pathology. …”
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Analyzing Influencing Factors of Uterine Rupture in Pregnant Women with Scarred Uterus Undergoing Repeat Delivery and Evaluating the Predictive Value of Lower Uterine Anterior Wall... by Zhang L, Li T, Zhang P, Li C

“…Liying Zhang,1,* Ting Li,1,* Pengming Zhang,1 Chunjuan Li2 1Department of Ultrasound Medicine, Zhangjiakou First Hospital, Zhangjiakou, Hebei Province, 075000, People’s Republic of China; 2Department of Obstetrics and Gynecology, Chongli Hospital, Peking University Third Hospital, Beijing, 076350, People’s Republic of China*These authors contributed equally to this workCorrespondence: Ting Li, Email tgps643@163.comObjective: To analyze influencing factors of uterine rupture in pregnant women with a scarred uterus undergoing repeat delivery and to investigate the predictive value of transabdominal ultrasound measurement of lower uterine anterior wall thickness.Methods: A retrospective analysis of 159 pregnant women with scarred uterus (March 2022–May 2024) divided into rupture group (n=48) and non-rupture group (n=111). …”
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Nephroprotective effect of atorvastatin at a dose of 80 mg in patients with ST-segment elevation myocardial infarction with an invasive treatment strategy by A. D. Gavrilko, E. M. Mezhonov, S. V. Shalaev, D. V. Krasheninin

“…To study the effectiveness of atorvastatin 80 mg, prescribed immediately prior emergency endovascular intervention, in reducing the incidence of acute kidney injury (AKI) defined by сontrast-induced nephropathy (CIN) and by Kidney Disease: Improving Global Outcomes (KDIGO) criteria in patients with ST-segment elevation myocardial infarction (STEMI).Material and methods. The study included 386 patients with STEMI. …”
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Mental Health Status of Patients with Thyroid Nodules: A Cross-Sectional Study by Wang P, Yan J, He H, Che Y

“…Peng Wang,1,* Jing Yan,2,* Honghai He,1 Ying Che1 1Medical Examination Center, Peking University Third Hospital, Beijing, People’s Republic of China; 2Peking University Sixth Hospital, Peking University Institute of Mental Health, NHC Key Laboratory of Mental Health (Peking University), National Clinical Research Center for Mental Disorders (Peking University Sixth Hospital), Beijing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Ying Che, Medical Examination Center, Peking University Third Hospital, North Garden Road & 49, Beijing, People’s Republic of China, Email cheyinghappy@126.comPurpose: This study aims to investigate the mental health status of patients with high-risk and low-risk thyroid nodules (TNs), and the potential psychological risk factors that may exist in patients with high-risk nodules.Patients and Methods: In this cross-sectional study, a total of 7645 adults who participated in physical examinations from January 2021 to December 2023 were included. …”
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Women on Management Board and Firm Performance: Evidence from The Visegrad Group Countries by Elżbieta Bukalska, Tomasz Sosnowski, Anna Wawryszuk-Misztal

“…Research Design & Methods: The study focuses on 451 publicly traded companies in the V4 countries (i.e. …”
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Vitamin D and exercise improve VEGF-B production and IGF-1 levels in diabetic rats: insights the role of miR-1 suppression by Fatemeh Mazaheri, Rastegar Hoseini, Ahmad Gharzi

“…The effects of an eight-week AT program and Vit D on the expression of miR-1, IGF-1 genes, and VEGF-B in the cardiomyocytes of rats with T2DM. Methods This study was an experimental investigation. …”
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Effects of Parental Attitudes in Childhood on Depressive Symptoms Through Trait Anxiety and Negative Life Events in Adult Volunteers by Hayashida T, Kikkawa M, Masuya J, Ono M, Ito S, Nibuya R, Takashio O, Tamada Y, Hashimoto N, Inoue T

“…In this study, we investigated the associations among parental attitudes in childhood, TA, adult life events, and depressive symptoms to assess the mechanism of the development of depressive symptoms.Participants and Methods: This study was conducted between January and August 2014. …”
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Targeted Glioma Therapy via TMVP1 Peptide-Modified FLT4 Liposomes: A Novel Molecular Probe Strategy by Zhou Y, Chen L, Shang C, Hong Y, Zhang H

“…By functionalizing TMZ-loaded liposomes with TMVP1 (TMZ@Lip-TMVP1), we aimed to enhance glioma-specific targeting and therapeutic efficacy.Methods: FLT4 was validated as a therapeutic target for glioma by bioinformatics analysis, RT-qPCR, and immunofluorescence experiments. …”
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Drug therapy problems and associated factors among adult patients admitted to the surgical ward in a resource-limited setting by Taju Seid, Jemal Abdela, Mesay Dechasa, Shambel Nigussie, Shambel Nigussie

“…Therefore, this study aimed to assess the magnitude of DTPs and associated factors among adult surgical patients at study setting in Ethiopia.MethodsA hospital-based cross-sectional study was conducted at Wachemo University Comprehensive Specialized Hospital from January 1 to 30 March 2024. …”
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