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10121
APPLICABILITY OF SIMILARITY CONDITIONS TO ANALOGUE MODELLING OF TECTONIC STRUCTURES
Published 2015-09-01“…Belousov as a «realist» as he supported «the liberal point of view» [Methods of modelling…, 1988, p. 21–22], whereas M.V. …”
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10122
The Correlation Between the Expression Levels of Serum miR-19b and SOCS-1 mRNA and Clinical Symptoms in Patients with Allergic Rhinitis
Published 2025-04-01“…Zhaopeng Kang,1,* Lingling Di,2,* Yi Liu,3 Wei Qu,3 Yi Zeng,3 Xue Lu,3 Lixin Wang3 1Department of Andrology, Renmin Hospital, Hubei University of Medicine, Shiyan, Hubei, 442000, People’s Republic of China; 2Department of Otolaryngology Head and Neck Surgery, General Hospital of Ningxia Medical University, Yinchuan, Ningxia Hui Autonomous Region, 756099, People’s Republic of China; 3Department of Otolaryngology Head and Neck Surgery, Renmin Hospital, Hubei University of Medicine, Shiyan, Hubei, 442000, People’s Republic of China*These authors contributed equally to this workCorrespondence: Lixin Wang, Department of Otolaryngology Head and Neck Surgery, Renmin Hospital, Hubei University of Medicine, No. 39 Chaoyang Middle Road, Shiyan, Hubei, 442000, People’s Republic of China, Tel +86-719-8666352, Email 1043275363@qq.comObjective: To investigate the correlation between the expression levels of microRNA-19b (miR-19b) and suppressor of cytokine signaling 1 messenger RNA (SOCS-1 mRNA) in the serum of patients with allergic rhinitis (AR) and clinical symptoms.Methods: This prospective study included a total of 86 patients with allergic rhinitis who were admitted to the People’s Hospital Affiliated to Hubei University of Medicine from January 2022 to January 2023. …”
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10123
The First Case of Antimicrobial-Resistant Salmonella Stanley ST29 Diagnosed Secondary to Acute Cholecystitis
Published 2025-05-01“…Wenqing Wang,1,2,* Shufen Liu,3,* Minlan Zhang,3 Yan Chen,4 Yanru Liang,1,2 Shuqi You,1,2 Peijun Lv,4 Xuebin Xu,5 Fenghua Zhang3 1Department of Microbiology, Shanghai Pudong New Area Center for Disease Control and Prevention (Shanghai Pudong New Area Health Supervision Institute), Shanghai, People’s Republic of China; 2Fudan University Pudong Institute of Preventive Medicine, Shanghai, People’s Republic of China; 3Department of Laboratory Medicine, Zhoupu Hospital Affiliated to Shanghai University of Medicine and Health, Shanghai, People’s Republic of China; 4Department of Microbiology, Panzhihua City Center for Disease Control and Prevention, Panzhihua, People’s Republic of China; 5Division of Pathogen Testing and Analysis, Shanghai Center for Disease Control and Prevention, Shanghai, People’s Republic of China*These authors contributed equally to this workCorrespondence: Fenghua Zhang, Email zpyyzfh@163.comObjective: To analyze the phenotypic and genomic characteristics of a non-typhoidal Salmonella bile isolate from a patient with chronic diarrhoea secondary to acute cholecystitis.Methods: The patient presented with chronic diarrhoea lasting for two weeks, which was secondary to acute cholecystitis. …”
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10124
Digital Inclusion Pathways and Influencing Factors Among Older Adults in Outpatient Settings: A Grounded Theory Study
Published 2025-05-01“…This study aims to investigate the experiences, attitudes, and perceptions of older adults in outpatient regarding smart healthcare service in order to develop an explanatory digital inclusion pathway and construct a comprehensive path model for older adults.Patients and Methods: We conducted semi-structured interviews with 27 older adults in outpatients in Chongqing, China to understand their experiences, attitudes, and perceptions of attending smart healthcare services through theoretical sampling. …”
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10125
Integrating Deep Learning and Radiomics in Differentiating Papillary Thyroid Microcarcinoma from Papillary Thyroid Carcinoma with Ultrasound Images
Published 2025-07-01“…Bing Yu,1,2,* Huijuan He,3,* Qiao Zheng,2,* Yao Ai,2 Xianwen Yu,2 Sunjun Li,4 Ji Zhang,2 Juebin Jin,5 Xiance Jin,2,6 Wenliang Yu3 1Purchasing Center Department, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, 310020, People’s Republic of China; 2Radiation and Medical Oncology Department, Wenzhou Medical University First Affiliated Hospital, Wenzhou, 325000, People’s Republic of China; 3Radiation Oncology Department, Quzhou People’s Hospital, Quzhou, 324002, People’s Republic of China; 4Alberta College, Wenzhou Medical University, Wenzhou, 325000, People’s Republic of China; 5Medical Engineering Department, Wenzhou Medical University First Affiliated Hospital, Wenzhou, 325000, People’s Republic of China; 6School of Basic Medical Science, Wenzhou Medical University, Wenzhou, 325000, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xiance Jin, Radiation and Medical Oncology Department, Wenzhou Medical University First Affiliated Hospital, Wenzhou, 325000, People’s Republic of China, Email jinxc1979@hotmail.com Wenliang Yu, Radiation Oncology Department, Quzhou People’s Hospital, Quzhou, 324002, People’s Republic of China, Email wlyu1982@aliyun.comPurpose: The feasibility and accuracy of ultrasound-based radiomics, deep learning, and combined deep learning radiomics models were investigated in the differentiation of papillary thyroid carcinoma and papillary thyroid microcarcinoma to decrease the risk of overtreatment of papillary thyroid microcarcinoma.Methods: A total of 549 patients with confirmed 180 papillary thyroid carcinoma and 436 papillary thyroid microcarcinoma nodules from Hospital One were enrolled and randomly divided into training and validation cohorts at a ratio of 8:2 with 56 patients left as independent testing set 1. …”
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10126
Long Non-Coding RNA EPB41L4A-AS1 Serves as a Diagnostic Marker for Chronic Periodontitis and Regulates Periodontal Ligament Injury and Osteogenic Differentiation by Targeting miR-2...
Published 2025-02-01“…Rui Li,1,* Zhibin Huang,2,* Mengmeng Chen3 1Department of Stomatology, Affiliated Hospital of Nantong University, Nantong, People’s Republic of China; 2Medical Room, Nantong College of Science and Technology, Nantong, People’s Republic of China; 3Department of Stomatology, The Fourth Hospital of Harbin, Harbin, People’s Republic of China*These authors contributed equally to this workCorrespondence: Mengmeng Chen, Department of Stomatology, The Fourth Hospital of Harbin, No. 119, Jingyu Street, Daowai District, Harbin City, Heilongjiang Province, 150026, People’s Republic of China, Tel +86 0451-88029850, Email chenmengm74@163.comBackground: Several long non-coding RNAs (lncRNAs) are dysregulated in chronic periodontitis (CP).Purpose: The study aimed to elucidate the molecular mechanisms and clinical significance of lncRNA EPB41L4A antisense RNA 1 (EPB41L4A-AS1) in CP.Patients and Methods: This study enrolled 101 patients with CP and 90 subjects with healthy periodontal tissues. …”
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10127
Pattern of changes in morpho-densitometric parameters of magnocellular neurons of the hypothalamic paraventricular nucleus under restraint stress of different duration
Published 2023-12-01“…The aim of the work was to define the nature of changes in morpho-densitometric parameters of magnocellular neurons of the hypothalamic paraventricular nucleus in rats at 6, 15 and 21 weeks of restricted living space. Materials and methods. A total of 55 male Wistar rats aged 6-10 months were used and divided into 4 groups (1 – intact control, 10 rats; 2, 3 and 4 – experimental groups of 15 rats each, which were in conditions of restricted environmental space for 6, 15 and 21 weeks, respectively). …”
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10128
Effect of perioperative ONS combined with intestinal microecology in patients with colorectal cancer: a randomized clinical trial
Published 2025-05-01“…PurposeTo investigate the combined effects of oral nutritional supplement (ONS) and intestinal microecology on postoperative nutrition status, inflammatory response and intestinal flora regulation colorectal cancer (CRC) patients.MethodsThis prospective single-center randomized controlled trial (RCT) was conducted at Chongqing Yongchuan Hospital between December 2023 and December 2024. …”
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10129
Enhancing adoptive cancer immunotherapy with Vγ2Vδ2 T cells through pulse zoledronate stimulation
Published 2017-11-01“…Additionally, IL-15 increases the anti-tumor activity of murine αβ T cells in mice but its effect on the in vivo anti-tumor activity of human Vγ2Vδ2 cells has not been assessed.Methods Human Vγ2Vδ2 T cells were expanded by pulse or continuous zoledronate stimulation with IL-2 or IL-15. …”
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10130
m6A-Methylated NUTM2B-AS1 Promotes Hepatocellular Carcinoma Stemness Feature via Epigenetically Activating BMPR1A Transcription
Published 2024-12-01“…However, whether m6A has oncofetal characteristics remains unknown.Methods: Gene expression in HCC tissues and cells was detected using qPCR. …”
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10131
Comparative Genomic Analysis of Tigecycline Resistance Development in Clinical Acinetobacter baumannii Isolates
Published 2025-08-01“…The goal is to provide clinical insights into the development of tigecycline resistance in A. baumannii, with a focus on multidrug-resistant strains commonly associated with hospital-acquired infections.Methods: We conducted dynamic tracking of multidrug-resistant Acinetobacter baumannii (MDR-AB) infections in three patients to monitor changes in tigecycline sensitivity during antimicrobial therapy. …”
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10132
Effect of Uncertainty-Aware AI Models on Pharmacists’ Reaction Time and Decision-Making in a Web-Based Mock Medication Verification Task: Randomized Controlled Trial
Published 2025-04-01“…ObjectiveThis study aimed to determine the effects of black-box and uncertainty-aware AI advice on pharmacist decision-making and reaction time. MethodsRecruitment emails were sent to pharmacists through professional listservs describing a web-based, crossover, randomized controlled trial. …”
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10133
Severe soft tissue injuries in multiple trauma patients—a challenge we can meet? A matched-pair analysis from the TraumaRegister DGU®
Published 2025-02-01“…Concomitant soft tissue injuries represent a particular challenge, as they can lead to complications at any time of trauma care, hold a high risk of infection and often require multiple surgical interventions and interdisciplinary collaboration.MethodsThis retrospective, multicentric study used the TraumaRegister DGU® to examine the effect of open fractures and severe soft tissue injuries on outcome of multiple trauma patients. …”
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10134
Quantitative Assessment of Psychological Stress Changes Before and After Ureteral Stent Placement: A Prospective Observational Study
Published 2025-07-01“…This study aimed to quantitatively evaluate psychological stress changes before and after ureteral stent placement in order to better understand patients’ psychological needs during this common urological procedure.Methods: This prospective observational study with paired before-after measurements was conducted at Yangjiang Hospital of Traditional Chinese Medicine between November 2024 and March 2025. …”
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10135
Study on the Regulated Cell Death of Hypertrophic H9c2 Cells Induced by Au:Ag Nanoparticles
Published 2025-02-01“…The main objective of this work is to explore the susceptibility of cells due to exposure to Au:Ag NPs in conditions representing cardiometabolic diseases.Methods: Au:Ag NPs were synthesized in different molar ratios (Au:Ag, 100:0, 75:25, 50:50, 25:75, 0:100) using starch as a capping and reducing agent. …”
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10136
Therapeutic Potential of PDA@CeO2 in Suppressing Hepatic Stellate Cell Activation and Preventing Liver Fibrosis
Published 2025-07-01“…This study tests the hepatoprotective effects of PDA@CeO2 nanoparticles in scavenging ROS, inhibiting HSC activation, and delaying fibrosis, using 2D-SWE to assess treatment efficacy.Methods: In vitro, flow cytometry evaluated ROS levels in HSCs, scratch assays assessed migration, and α-SMA expression confirmed activation. …”
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10137
Systemic Immune-Inflammation Index (SII) and Neutrophil-to-Lymphocyte Ratio (NLR): A Strong Predictor of Disease Severity in Large-Artery Atherosclerosis (LAA) Stroke Patients
Published 2025-01-01“…This study aimed to verify the predictive value of the clinical parameters such as systemic immune-inflammation index (SII) and neutrophil-to-lymphocyte ratio (NLR) for the severity in Large Artery Atherosclerosis (LAA) stroke patients.Methods: The SII is defined as platelet × (neutrophil count/lymphocyte count), the NLR is defined as neutrophil count/lymphocyte count. …”
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10138
Chaihuang Qingfu Pills Protect Against Acute Pancreatitis—Associated Acute Lung Injury Through MMP9-NLRP3-Pyroptosis Pathway
Published 2025-02-01“…However, its role in SAP-ALI and the underlying mechanisms remain unclear.Methods: 92 AP patients were enrolled to observe the protective effect of CHQF on AP-ALI. …”
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10139
Robot-assisted laparoscopic ureteropelvic junction plasty in children using the da Vinci Xi robotic system: a Russian first experience
Published 2025-06-01“…To conduct a comprehensive analysis of the experience in performing RALP in pediatric patients using the da Vinci Xi robotic platform. Materials & methods. Between July and October 2024, a total of 14 robot-assisted laparoscopic pyeloplasties (RALP) were successfully performed. …”
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10140
Liver Function Abnormalities in Patients with Chlamydia psittaci Pneumonia: A Multicenter Retrospective Study
Published 2025-06-01“…In this study, we aimed to elucidate the characteristics of liver function changes and the factors influencing liver injury in patients with Chlamydia psittaci pneumonia, providing a reference for clinical treatment.Methods: The clinical data of patients with Chlamydia psittaci pneumonia admitted to three tertiary Grade A hospitals in Guangdong Province, China, from January 2020 to February 2025 were retrospectively collected. …”
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