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Suggested Topics within your search.
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10001
Ductular reaction or hepatic reparative complex: immunohistochemical features in liver cirrhosis in patients with chronic hepatitis
Published 2018-04-01“…To characterize the pathomorphological features and significance of the ductular response in liver cirrhosis in patients with chronic non-alcoholic, alcoholic and viral hepatitis in hepatobioptats with the use of immunohistochemical (IHC) techniques. Material and methods of investigation. Histological, histochemical and IHC study of the ductular liver reaction in liver biopsies of 52 patients aged 24 to 66 years with cirrhosis of the liver on the background of non-alcoholic steatohepatitis (13 patients), and alcoholic steatohepatitis (13 patients) and on the background of chronic viral hepatitis C (10 patients, 26–47 years), as well as those suffering from severe biliostasis (8 patients) and focal nodular liver hyperplasia (8 patients). …”
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10002
The Hourly Apnea-Hypopnea Duration Better Correlates with OSA-Related Nocturnal Hypoxemia and Excessive Daytime Sleepiness Rather Than AHI
Published 2025-05-01“…This study evaluated whether hourly apnea-hypopnea duration (HAD) and mean apnea-hypopnea duration (MAD) could complement or outperform AHI.Methods: This study included 1069 OSA patients, of whom 754 completed the Epworth Sleepiness Scale (ESS). …”
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10003
Synthesis and properties of magnetically sensitive nanocomposites based on magnetite and gemcitabine
Published 2018-11-01“…It has been determined by the magnetic granulometry methods that the thickness of GC shell in the composition of Fe3O4/GC NC is (2.4±0.1) nm. …”
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10004
GALNT14 Genetic Variants Harbor Differential Prognostic Values Linking to Distinct Macrophage Cell Types in Hepatocellular Carcinoma
Published 2025-08-01“…This study aims to identify an SNP panel to improve prognosis prediction and explore its role in modulating tumor-infiltrating immune cells (TIICs).Patients and Methods: We included 345 HCC patients underwent surgical resection: 15 in the exploration cohort and 330 in the validation cohort. …”
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10005
Triglycerides and HDL Cholesterol Mediate the Association Between Waist Circumference and Hyperuricemia in Normal-Weight Men
Published 2024-12-01“…The aim of this research was to explore the mediating roles of TG and HDL-C in the association between WC and hyperuricemia in normal-weight men.Methods: A retrospective observational study was conducted among normal-weight men (18.5 ≤ BMI < 24 kg/m2) aged ≥ 18 years who underwent health checkups in Nanjing from 2021– 2023. …”
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10006
Epidemiology and Molecular Drug-Resistance Patterns of Tuberculosis in Non-Elderly Patients in Luoyang, China, 2019-2023
Published 2025-06-01“…This study aimed to analyze TB transmission and molecular resistance profiles among non-elderly patients (< 60 years) in Luoyang City.Patients and Methods: From 2019– 2023, 24,706 non-duplicate sputum samples from 10 TB-designated hospitals were tested for Mycobacterium tuberculosis complex (MTBC) via IS6110-targeted real-time PCR. …”
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10007
The study of the elemental composition of peppermint (Mentha piperita)
Published 2014-12-01“…Studying qualitative structure and quantitative content of macro - and microelements in leaf of 3 samples of peppermint became the purpose of our research. Materials and methods of research The peppermint leaves of 3 samples were the object of our research. …”
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10008
The Effects of M2 Macrophages-Derived Exosomes on Urethral Fibrosis and Stricture in Scar Formation
Published 2025-03-01“…This study aimed to investigate the possible effects of M-Exos on the initiation and development of urethral fibrosis and stricture after injury, and to elucidate the underlying mechanisms.Methods: In this study, we used time-tracking immunofluorescence staining for M1 and M2 macrophage markers to characterize sequential properties in the site of injured urethra. …”
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10009
Challenges to creating primary care teams in a public sector health centre: a co-operative inquiry
Published 2007-02-01“…The teams depended on effective collaboration between the doctors and the CNPs. Methods: A co-operative inquiry group, consisting of two facility managers, an administrator, and medical and nursing staff, met over a period of nine months and completed three cycles of planning, action, observation and reflection. …”
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10010
Association Between Systemic Immune-Inflammation Index in Early Pregnancy and Preeclampsia: A Multicenter Cohort Study
Published 2025-06-01“…The development of preeclampsia (PE) may be attributed to an excessive systemic inflammatory response in pregnant women, however, the relationship between SII and PE remains unclear.Methods: This study included 47,480 singleton pregnant women from three hospitals, comprising 2489 PE patients and 34,835 healthy controls. …”
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10011
Heart Rate Variability in Young Adults with Bronchial Asthma with and without Previous COVID-19 Infection: A Cross-sectional Study
Published 2025-08-01“…Aim: To compare HRV parameters between young adult bronchial asthma patients with and without a history of COVID-19, and assess the extent of autonomic dysfunction attributable to COVID-19. Materials and Methods: This cross-sectional study included 100 bronchial asthma patients aged 20-40 years, equally divided into two groups based on COVID-19 history. …”
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10012
Comprehensive Bioinformatics Analyses and Experimental Validation of the Cell Cycle Related Protein SAPCD2 as a New Biomarker and Potential Therapeutic Target in Pancreatic Cancer
Published 2025-02-01“…However, no comprehensive study has explored its expression and regulation, discussed its role in tumor prognosis and immune modulation, along with therapy response in pan-cancer until now.Methods: SAPCD2 expression was analyzed using data from The Cancer Genome Atlas database (TCGA) and Human Protein Atlas (HPA) database. …”
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10013
Clinical Characteristics and Risk Factors for Blood Culture-Positive Klebsiella pneumoniae Liver Abscess: A Retrospective Study
Published 2025-05-01“…This study aimed to investigate the clinical characteristics of patients with blood culture-positive KPLA and identify potential predictive indicators.Methods: We performed a retrospective analysis of clinical data from 263 KPLA patients diagnosed at our hospital between January 2019 and December 2023. …”
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10014
Whole Transcriptome-Based ceRNA Regulatory Network Analysis of Radiation-Induced Esophageal Epithelial Cell Injury
Published 2025-04-01“…This study aimed to investigate the effects of ionizing radiation on human esophageal epithelial cells and explore the role of the ceRNA network in this injury.Methods: Cellular phenotype experiments assessed the effects of ionizing radiation on human esophageal epithelial cells. …”
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10015
Anatomical and morphological features of the heart of a domestic dog (Canis Lupus Familiaris L., 1758)
Published 2024-02-01“…For the work, complex morphological research methods were used: anatomical, histological, organo-, histo- and cytometric, statistical, thanks to which new data on the peculiarities of the macro-, histo- and cytomorphometric characteristics of the morphological structures of the heart in the studied animals were presented. …”
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10016
Biospeckle Optical Coherence Tomography in Visualizing the Heat Response of Skin: Age-Related Differences
Published 2024-11-01“…Currently, research related to the visualization of cutaneous vascular changes to heat stress depending on age and gender is limited to methods such as laser Doppler flowmetry and plethysmography, which do not provide any spatially resolved information at high resolution. …”
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10017
Effects of Prophylactic Infusion of Equivalent Doses of Norepinephrine and Phenylephrine in Preventing Spinal Anesthesia-Induced Hypotension During Cesarean Delivery on Fetal and M...
Published 2025-06-01“…We aimed to compare the effects of norepinephrine and phenylephrine at equivalent doses on fetal and maternal outcomes, and assess their efficacy at the 90% effective dose (ED90).Methods: A total of 100 parturients scheduled for cesarean delivery were randomly allocated to receive either 0.10&nbsp;&mu;g/kg/min norepinephrine (Group NE) or 0.60&nbsp;&mu;g/kg/min phenylephrine (Group PE) to prevent spinal anesthesia-induced hypotension. …”
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10018
A Nomogram Based on Fibrinogen-to-Neutrophil Ratio as a Novel Predictor of Lymph Node Metastasis in Patients with Cervical Cancer and Type 2 Diabetes Mellitus
Published 2025-05-01“…In this regard, we propose the fibrinogen-to-neutrophil ratio (FNR) as an innovative and promising biomarker for evaluating pelvic lymph node metastasis in cervical cancer patients with type 2 diabetes.Methods: The study was conducted on 141 patients diagnosed with cervical cancer and concomitant type 2 diabetes, who were treated at the First Affiliated Hospital of Xiamen University. …”
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10019
Gender-Related Characterization of Acne in Chinese: A Multiple-Center Cross-Sectional Survey on 13085 Cases
Published 2024-12-01“…Other gender-related characteristics of acne have not been well elucidated yet.Objective: We compared characteristics of skin lesions, severity and risk factors of acne between males and females in Chinese.Methods: Investigator-administered questionnaire was used to collect demographic data, clinical feature and risk factors of acne from May 2020 to August 2021. …”
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10020
A Pan-Cancer Analysis of Natriuretic Peptide Receptor 3 (NPR3) with Clinical Cohort and in vitro Validation
Published 2025-07-01“…This study aimed to comprehensively analyze NPR3’s role across multiple cancers, focusing on its potential as a prognostic biomarker, particularly in kidney cancer.Methods: A comprehensive pan-cancer study of NPR3 was conducted using 20 different databases and datasets. …”
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